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Transgenics and Cloning

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	Mouse Genome Informatics - http://www.informatics.jax.org/ MGI (A Jackson laboratory resource) provides integrated access to data on the genetics, genomics, and biology of the laboratory mouse.
	Harwell Mutagenesis Programme - http://www.mut.har.mrc.ac.uk/ A large scale mouse genetics programme to identify new phenotypes of relevance to human disease through ENU mutagenesis.
	MMRRC: Mutant Mouse Regional Resource centers - http://www.mmrrc.org/index.html A repository of mouse stocks and ES cell line collections serving the world-wide genetics and biomedical research community for the benefit of human health.
	Herbert Irving Comprehensive Cancer Center :Transgenic Mouse Facility - http://cpmcnet.columbia.edu/research/equip/eq-cctrn.htm The Facility produces transgenic mice by microinjecting investigator-provided DNA into fertilized mouse eggs and chimeric mice by microinjecting embryonic stem (ES) cells into mouse blastocysts.
	Yale Transgenic Mouse and Gene Targeting Resource - http://info.med.yale.edu/transgen/ Produces transgenic and knock out mice for cancer center members and members of the Yale community.

	Deltagen and Lexicon Knockout Mice - http://www.informatics.jax.org/external/ko/ A database of select mutant mice and frozen embryo stocks created and characterized by Deltagen Incorporated and Lexicon Genetics Incorporated. Available for use without restrictions for academic and not-for-profit institutions.
	University of Michigan Transgenic Animal Model Core - http://www.med.umich.edu/tamc/ The Transgenic Core routinely prepares transgenic mice and mice with targeted mutations for University of Michigan investigators.
	CMHD ENU Mutagenesis - http://www.cmhd.ca/ Centre for Modeling Human Disease (CMHD) use genome-wide ENU based random mutagenesis in mice to discover new genes and create new mouse models.
	EMMA - the European Mouse Mutant Archive - http://www.emma.rm.cnr.it/ The European Mouse Mutant Archive (EMMA)is a non-profit repository for the collection, archiving (via cryopreservation) and distribution of relevant mutant strains essential for basic biomedical research.
	International Mouse Strain Resource - http://www.informatics.jax.org/imsr/IMSRSearchForm.jsp IMSR is a searchable online database of mouse strains and stocks available worldwide, including inbred, mutant, and genetically engineered mice.

	Trans-NIH Mouse Initiative - http://www.nih.gov/science/models/mouse/ This site will provide information on: follow-up meetings to the initial March meeting; funding opportunities for mouse genomics and genetics resources; major resources-producing grants funded in response to the initiative; progress toward meeting the goals of the initiative; major mouse genomics and genetics resources; courses and scientific meetings related to the mouse initiative; and selected reports and publications.
	Tennessee Mouse Genome Consortium - http://tnmouse.org The Consortium's purpose is to promote mouse models for human genetic diseases and as subjects for the study of gene function.
	Riken Large Scale Mutagenesis Program - http://www.gsc.riken.go.jp/Mouse/main.htm A large scale mouse ENU mutagenesis project at Riken GSC, Japan.
	UC-Davis Transgenic Mouse Research - http://tgmouse.compmed.ucdavis.edu/ Transgenic histopathology laboratory at the University of California-Davis providing comprehensive light and electron microscopic analysis of tissues submitted by interested investigators .
	Transgenic Animal Web - http://www.med.umich.edu/tamc/links.html Links to useful transgenic resources

	Gene Targeting and Transgenic Facility - http://www.healthsystem.virginia.edu/internet/transgenic-mouse/ GTTF, at the University of Virginia, produces and preserves genetically engineered mouse strains for animal model research.
	SUNY-Stony Brook Transgenic Mouse Facility - http://www.pharm.sunysb.edu/transgenic/ Consult and conduct transgenic (pronuclear DNA injection) and gene-targeting projects in mice.
	BCM Mouse Genome Project - http://www.mouse-genome.bcm.tmc.edu/ENU/MutagenesisProj.asp Large scale ENU based mouse mutagenesis for developmental defects
	Transgenic Mouse Facility - http://www.research.uci.edu/tmf/ This facility at UC Irvine provides services on a recharge basis for making, breeding, genotyping, importing and preserving genetically-modified mice.
	Upenn Transgenic and Chimeric Mouse Facility - http://www.med.upenn.edu/tcmf/ Provides a centralized service to efficiently produce transgenic mice for basic research. At the University of Pennyslyvania.

	UC-Irvine Transgenic Mouse Facility - http://darwin.bio.uci.edu/~tjf/index.html Home Page of the Transgenic Mouse Facility at UC-Irvine. The TMF is a core facility serving the UCI community, other UC campuses, and outside collaborators of UC researchers.
	The Case Transgenic and Targeting Facility - http://ko.cwru.edu/ Provide transgenic, targeting, targeted point mutations, chimera, rederivation and cryopreservation services for the Cleveland Biomedical Research Community. Includes mouse breeding FAQs, costs, and protocols.
	The Cancer Center at Washington University (St. Louis) - ES Core - http://medicine.wustl.edu/~escore/ The Embryonic Stem Cell Core has been created to help create mutations in murine embryonic stem cells. The core has several missions, including development of state-of-the-art reagents for the production of targeted mutations in embryonic stem cells, the creation of quality-controlled embryonic stem cell lines, and the teaching of methods for embryonic stem cell culture and manipulation.
	KUMC :Transgenic and Gene-targeting Institutional Facility - http://www.kumc.edu/TGIF/ The Transgenic and Gene-targeting Institutional Facility (TGIF) at the University of Kansas Medical Center (KUMC) provides a centralized facility for production of transgenic mice.
	Medical College of Wisconsin : Transgenic Core Facility - http://hmgc.mcw.edu/platforms/Transgenic_Core_Facility/ Services include transgenic mouse production by microinjection of oocytes, gene targeting in ES cells, generation of ES cell chimeras, and embryo cryopreservation.

	Transgenic Mouse / Embryonic Stem Cell Shared Resource - http://www.vcscb.org/shared_resource/ Provides transgenic or gene knockout mice. At the Vanderbilt-Ingram Cancer Center.
	University of Texas Health Science Centre at Houston - http://www.uth.tmc.edu/uth_orgs/imm/centers/scheduleofservices.htm The Laboratory for Developmental Biology is a shared service support facility of the Institute in which embryonic stem cell lines, knock-out mice and transgenic mice are being produced.
	Transgenic Models of Skin Disease Core at Harvard - http://dermatology.bwh.harvard.edu/transgenic.html At the Harvard Skin Disease Research Center. Mainly provides services for the generation of mouse skin disease models.
	John Curtin School, ANU : Gene Targeting Laboratory Research, - http://jcsmr.anu.edu.au/dbmb/matthaei/genere.htm Gene targeting laboratory at The John Curtin School of medical research, Australian National University.
	German Gene Trap Consortium (GGTC) - http://tikus.gsf.de/ The German Genetrap Consortium (GGTC) generates a reference library of gene trap sequence tags (GTST) from insertional mutations generated in mouse embryonic stem (ES) cells.

	UF Shands Cancer Center-Transgenic Mouse Core Facility - http://transgenics.ufscc.ufl.edu/ University of Florida Shands Cancer Center. Transgenic Mouse Core Facility.
	McLaughlin Research Institute - http://www.montana.edu/wwwmri/index.html Not-for-profit mouse mutagenesis program.
	UCSD Transgenic Mouse Core - http://cancer.ucsd.edu/tgm/ The Transgenic Mouse and Embryonic Stem Cell Gene Targeting Core is a state-of-the-art facility that has an outstanding track record in the production of genetically altered mice.
	UTMB Transgenic Mouse Facility - http://www2.utmb.edu/scccb/mouse/default.asp This state-of-the art facility, supported by the Sealy Center for Cancer Cell Biology, is available for use by all UTMB scientists.
	University of Missouri-Columbia Transgenic Animal Core - http://www.biotech.missouri.edu/tac/ University of Missouri-Columbia Transgenic Animal Core

	University of Hawaii - http://www.hawaii.edu/ur/News_Releases/NR_July98/cloning.html News release that was reported in the journal nature concerning the first reproducible cloning of mammals from adult cells.
	Transgenic Animal Service of Queensland - http://tasq.uq.edu.au/ Service run by the University of Queensland's Institute for Molecular Biosciences which provides transgenic mice and other related services for Australian Science.
	Purdue University Transgenic Mouse Core Facility - http://www.bio.purdue.edu/research/groups/tmcf/index.htm Serves as a centralized resource for the production of transgenic and gene-targeted mice for Purdue investigators.
	Boston University Knock Out Mouse Core Facility - http://www.bumc.bu.edu/Departments/HomeMain.asp?DepartmentID=439 Offers transgenic mouse services for the Boston University medical campus.
	CGDN Transgenic Core Facility - http://www.cmmt.ubc.ca/research/core_facilities/transgenic/ The CGDN Core Facility offers investigators with efficiency and quality in transgenic and knock-out mouse technologies.

	Mount Sinai School of Medicine: Mouse Genetics Shared Research Facility - http://www.mssm.edu/research/resources/mouse_genetics_notsinai.shtml The institutional Mouse Genetics Research Facility has been established to provide the Mount Sinai research community with access to state-of-the-art facilities for the production of transgenic and knockout mice.
	Mouse Genotyping Services - http://mousegenotype.com/ Biotechnology company providing affordable mouse genotyping services with no set up fees and quick turn around.
	University of Kentucky Transgenic Facility - http://www.uky.edu/OtherOrgs/Transgenic The facility provides state-of-the-art equipment and expertise essential for producing transgenics and maintains a mouse colony.
	UMass Medical School:Transgenic Knockout Animal Core Facility - http://www.umassmed.edu/tkomouse/ The mission of the Transgenic-Knockout Animal Core Facility is to produce genetically-altered mice for the UMASS Medical School Community.
	Cre-lox Plasmids - http://www.geocities.com/brian_sauer%40sbcglobal.net/ Cre-lox DNA recombination is used extensively for designing transgenic/knockout mice. This site provides short descriptions and technical information for various Cre-lox DNA vectors and links to relevant resources.

	UM SCCC --Gene Knockout and Transgene Facility - http://www.sylvester.org/Research/home.cfm?s=28&e=255 The University of Miami Transgenic and Targeted Mutant Mouse Core Facility is subsidized by the Sylvester Comprehensive Cancer Center. The primary objective of the facility is to efficiently produce transgenic mice and targeted-mutant mice
	Mouse Phenome Database - http://aretha.jax.org/pub-cgi/phenome/mpdcgi?rtn=docs/home MPD (A Jackson laboratory resource) provides a collection of phenotypic and genotypic data for the laboratory mouse.
	ORNL Mutant Mouse Database - http://bio.lsd.ornl.gov/mouse/ Collection of several hundred mouse stocks, most of which propagate mutations induced by radiations or chemicals in various stages of male or female gametogenesis.
	Wadsworth Center -Transgenics and Gene Knockout - http://www.wadsworth.org/cores/transgen.htm Transgenics and Gene Knockout - Wadsworth Center Core Facilities, New York State Department of Health.
	MCDB Transgenic Facility - http://mcdb.colorado.edu/facilities/transgenic-facility/ Provides a barrier environment for the housing of valuable strains of mice and a core facility for use in the generation of transgenic mice. University of Colorado, Boulder.

	Transgenic Core Facility - http://www.stjude.org/stjude/v/index.jsp?vgnextoid=d19d6f9523e70110VgnVCM1000001e0215acRCRD&vgnextchannel=5d58797030dd4110VgnVCM1000001e0215acRCRD Produces transgenic and knockout mice for the researchers at St. Jude Children's Research Hospital (SJCRH).
	Animal Models Core Facility - http://www.omrf.org/OMRF/Core/AnimalModels/ University of North Carolina at Chapel Hill. The Facility makes animal models of human disease for medical researchers by creating genetically modified mice. Transgenic and gene-targeted animals are generated from DNA constructs provided by clients.

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