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Nov 20, 2020 · Phylogenetic tree of JmjC domain-containing histone demethylases from G. hirsutum (Gh), G. arboreum (Ga), G. raimondii (Gr), Arabidopsis (At) ...
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Few inhibitors have been identified to target the JmjC domain-containing histone demethylases. N-oxalylglycine and its derivatives inhibit KDM2A, KDM2C and ...
Previous publications on characterization of other JmjC domain-containing histone demethylases have pointed to the critical role of the JmjC domain for ...
The majority of histone demethylation is carried out by the JmjC-domain containing histone demethylases, which belong to the family of oxygen- iron- and 2 ...
Feb 6, 2019 · Epigenetic Drug Discovery. Chapter 11. JmjC-domain-Containing Histone Demethylases. Christoffer Højrup,. Christoffer Højrup. University of ...
... JmjC domain-containing histone demethylases have been linked to cancer (14–16). However, the mechanisms of their oncogenic activities are not well ...
JmjC domain-containing histone demethylases bind methylated histone substrates and discriminate among the different methylation states on modified lysine ...
JmjC-domain-containing histone demethylases of the JMJD1B type as putative precursors of endogenous DSIP. Author links open overlay panelInessa I.Mikhaleva ...
Apr 1, 2019 · ... (JmjC domain-containing histone demethylases), the demethylases containing the JmjC domains, remove the methyl groups through hydroxylation ...
... JmjC domain-containing histone demethylases. Furthermore, only a small percentage of JmjC domain-containing proteins have been characterized. We believe ...