Chromosome segregation—the partitioning of genetic material into two daughter cells—is one of the most crucial processes in cell division. In all Eukaryotes, chromosome segregation is driven by the spindle, a microtubule-based, self-organizing subcellular structure.
Feb 22, 2021
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Chromosome segregation
Chromosome segregation is the process in eukaryotes by which two sister chromatids formed as a consequence of DNA replication, or paired homologous chromosomes, separate from each other and migrate to opposite poles of the nucleus. This... Wikipedia
Feb 8, 2017 · Lastly, chromosome segregation errors during gamete formation in meiosis are a primary cause of human birth defects and infertility. This review ...
Apr 5, 2023 · Most chromosome segregation errors in mitosis and meiosis are avoided by the action of the spindle assembly checkpoint (SAC) that monitors the ...
Chromosome segregation begins with the alignment of chromosomes at the metaphase plate, and ends when chromosomes have completed movement to the spindle poles.
Aneuploidy is a direct consequence of chromosome segregation errors in mitosis, whereas structural aberrations are caused by improperly repaired DNA breaks.
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