Fatty acid elongation occurs in three cellular compartments: the cytosol, mitochondria, and endoplasmic reticulum (microsomes). In the cytosol, fatty acid elongation is part of de novo lipogenesis and involves acetyl-CoA carboxylase and fatty acid synthase.
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Jun 10, 2021 · The first step in the fatty acid elongation cycle is catalyzed by the 3-keto acyl-coenzyme A (CoA) synthases (in mammals, ELOVL elongases).
Jun 10, 2021 · The first step in the fatty acid elongation cycle is catalysed by the 3-keto acyl-CoA synthases (in mammals, ELOVL elongases). Although ELOVLs ...
VLCFAs are elongated by an endoplasmic reticulum-localized fatty acid elongation complex of four core enzymes, which sequentially add two carbon units to a ...
Jun 10, 2021 · Fatty acid elongation is initiated by a condensation reaction (1) catalyzed by one of two condensing enzymes (ELO or KCS) with acyl-CoA (n = 14– ...
Elongation: Mitochondrial Fatty Acid Elongation, a Minor Pathway · Desaturation: The Overall Reaction · Desaturation: Specificity · Previous Page ...
Sep 14, 2012 · Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae. ,.
Mitochondrial fatty acid elongation acts primarily on fatty acyl CoA substrates shorter than 16 carbons. Notice that here acetyl CoA is the source of the added ...
Fatty acid elongation pathway adds two carbon units to a typically much longer starter molecule. FAE pathway operates using single monofunctional ...
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