Feb 27, 2024 · Study identified Unpaired 2 (Upd2), a protein with similarities to type I cytokines, as a secreted factor produced by the fat body in the fed ...
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What is the unpaired 2 gene in Drosophila?
Nov 3, 2020 · Upd2 shares several features with its vertebrate counterpart, leptin: both measure adiposity, respond to nutritional surplus or scarcity, and ...
Upd2 activates JAK/STAT signaling in a population of GABAergic neurons that project onto the IPCs. This activation relieves the inhibitory tone of the GABAergic ...
Here, we describe our analysis of the only invertebrate JAK/STAT pathway ligands identified to date, the Drosophila unpaired-like family. We show that upd2 is ...
May 26, 2021 · Accurate and continuous monitoring of energy stores maintains neural tone and drives behavioral decisions critical for survival in both ...
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The UPD Series universal pulse divider accepts pulse signals from devices such as electric meters and flow sensors, rescales these pulses, and provides an ...
Enables cytokine activity. Involved in several processes, including cell surface receptor signaling pathway via JAK-STAT; intestinal epithelial structure ...
Maternal uniparental disomy of chromosome 2 is an uniparental disomy of maternal origin that most likely does not have any phenotypic expression except from ...
Feb 18, 2022 · We illustrate that Upd2's nuclear retention is critical to fat mobilization and increased starvation resilience. Furthermore, nuclear Upd2 ...
Dec 12, 2023 · A third gene, outstretched or unpaired (upd), with the distinctive embryonic mutant phenotype of hop and stat92E, has now been cloned. It is ...