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Aug 16, 2022 · Abstract. Antisense oligonucleotides (ASOs) are single-stranded nucleic acid strings that can be used to selectively modify protein synthesis by ...
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What is an allele-specific oligonucleotide probe?
What is ASO oligo?
What is the allele specificity?
What is the ASO PCR method?
An allele-specific oligonucleotide (ASO) is a short piece of synthetic DNA complementary to the sequence of a variable target DNA. It acts as a probe for ...
Aug 16, 2022 · Here, we provide an overview of current strategies to develop personalized, allele-specific ASO therapies for the treatment of neurodegenerative ...
The ASO probe (allele-specific oligonucleotide) is used to detect the presence of a specific DNA sequence or to visualize a specific polymerase chain reaction ( ...
Study of SNP-Selective Knockdown in Mice. (A) Allele-specific mRNA quantitation from mouse left ventricle (LV; 8-week-old males) 1 week following ASO dosing (*p ...