Sep 1, 2018 · The WT1 gene provides instructions for making a protein that is necessary for the development of the kidneys and gonads.
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Apr 11, 2024 · This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding ...
Jul 4, 2023 · WT1 is a true chameleon, both acting as an oncogene and tumor suppressor. As its exact role in leukemogenesis is still ambiguous, research with ...
The WT1-related Wilms tumor (WT) syndromes are a group of hereditary disorders caused by alterations in a gene known as WT1.
Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533). Recognizes and binds to the DNA sequence ...
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the ...
WT1 is a transcription factor that through DNA binding regulates numerous genes. WT1 is crucial for development of the kidney and genitalia. In the mature ...