U5 snRNA is a small nuclear RNA (snRNA) that participates in RNA splicing as a component of the spliceosome. It forms the U5 snRNP (small nuclear ...
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Umen JG, Guthrie C. A novel role for a U5 snRNP protein in 3' splice site selection. ... The HeLa 200 kDa U5 snRNP-specific protein and its homologue in ...
The U5 snRNP is a large complex consisting of the U5 snRNA, a ring of seven Sm proteins and eight core protein factors (Table 1; Will and Luhrmann, 2011).
Mar 11, 2024 · U5 tri-snRNP, the major building block of the precatalytic spliceosome. CD2BP2 is a hallmark protein of the 20S U5 snRNP, absent from the mature ...
The role of U5 snRNP in pre-mRNA splicing. EMBO J. 1997 Oct 1;16(19):5797-800. doi: 10.1093/emboj/16.19.5797. Author. A J Newman. Affiliation. 1 MRC ...
Mar 11, 2024 · The human U5 snRNP is the ~1 MDa 'heart' of the spliceosome and is recycled through an unknown mechanism involving major architectural ...
This strongly suggests that U5 snRNP protein(s) may play a role in modulating or stabilizing RNA–RNA contacts between the U5 snRNA terminal loop and exon ...
U5 snRNP-specific 40 kDa protein; WD repeat-containing protein 57. Gene names ... Part of the U5 snRNP complex. Interacts with PRPF8. Component of the U4/U6-U5 ...
The human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6.U5 tri-snRNP bridging protein, but dissociates upon tri-snRNP formation.