Apr 3, 2024 · The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome ...
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Apr 3, 2023 · XPC gene. XPC complex subunit, DNA damage recognition and repair factor. Email this page to a friend Facebook Twitter Pinterest Download PDF.
XPC, RAD4, XP3, XPCC, p125, xeroderma pigmentosum, complementation group C, XPC complex subunit, DNA damage recognition and repair factor. External IDs, OMIM ...
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Apr 21, 2022 · While the XPC complex is typically sufficient to identify NER-repaired DNA lesions, some minimally strand-distorting lesions, such as UV-induced ...
Jan 25, 2019 · Two-step recognition of DNA damage for mammalian nucleotide excision repair: directional binding of the XPC complex and DNA strand scanning.
The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide ...
The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or ...
The XPC complex is the initiator and main DNA damage sensor in global genome nucleotide excision repair (GG-NER), one of two branches of the nucleotide excision ...
Jan 6, 2015 · The xeroderma pigmentosum C (XPC) complex initiates nucleotide excision repair by recognizing DNA lesions before recruiting downstream factors.