Activation of glucagon receptor (Gcgr) signaling promotes glycogenolysis and enhanced gluconeogenesis, and regulates pathways controlling hepatic lipid oxidation and lipid secretion.
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Administration of this bicyclic 19-residue peptide BI-32169 showed a strong reduction in human glucagon receptor activity in a cell-based experiment [43].
G protein-coupled receptor activity · guanyl-nucleotide exchange factor activity · signal transducer activity · peptide hormone binding · glucagon receptor activity ...
glucagon receptor activity. Source:UniProtKB. 2 publications. Molecular Function, guanyl-nucleotide exchange factor activity. Source:Reactome. Molecular ...
2010-06-08, Updated, TERM, glucagon receptor activity ; 2008-10-10, Added, RELATION, is a GO:0004930 (G protein-coupled receptor activity).
glucagon receptor activity. Definition: Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein ...
Disruption of glucagon receptor activity has also been described in the Gcgr-/- mouse. Gcgr-/- mice exhibit a number of unexpected and striking phenotypes ...