pro-B cell differentiation Gene Ontology Term (GO:0002328) Definition: The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
People also ask
What is meant by B cell differentiation?
What is the difference between pro-B cells and pre-B cells?
What activates proliferation and differentiation of B cells?
What do pro-B cells express?
... pro-B cell differentiation is dependent on pre-B cell receptor expression. J. Immunol. 1998;161:6038–6045 . [PubMed] [Google Scholar]; Ray R.J., Stoddart A ...
Jun 13, 2011 · Pro-B Cell Differentiation Is Impaired by Stable Noncoding μH mRNA. ... Nevertheless, we ruled out some explanations for the impairment in pro-B ...
Sep 1, 2019 · Fahl SP, Crittenden RB, Allman D, Bender TP. C-Myb is required for pro-B cell differentiation. J Immunol. 2009;183(9):5582–92. Article CAS ...
Oct 1, 2014 · We recommend. c-Myb Is Required for Pro-B Cell Differentiation. Shawn P. Fahl et al., J Immunol, 2009. Focal Adhesion Kinase Regulates the ...
Pro-B cell differentiation into pre-BI cells is characterized by loss of CD34 and TdT, and acquisition of cytoplasmic μHC in more than 95% of the cells.22 ...
Our results provide clear evidence that responses through the IL-7R are modulated during pro-B cell differentiation in a pre-BCR-dependent fashion. Our results ...
GO:0002328 JSON. pro-B cell differentiation. Biological Process. Definition (GO:0002328 GONUTS page). The process in which a precursor cell type acquires ...
Dec 2, 2016 · ... Pro-B cell differentiation into osteoclasts by 70% (p<0.05) (Figure 1D). Conceivably, in other scenarios, e.g., sex hormone deficiency ...
We find that Ebf+/−E2a+/− mice display a marked defect in pro-B cell differentiation at a stage later than observed in the single homozygous mutant mice.