Helicos Biosciences Corporation is a United States-based life science company. The Company develops genetic technologies for the research, drug discovery and clinical diagnostics markets. The Company's True Single Molecule Sequencing (tSMS(TM)) technology allows the direct measurement of natural DNA without the confounding steps of sample manipulation or nucleic acid amplification. It offers a Helicos Genetic Analysis System, is comprised of the HeliScope Sequencer, HeliScope Sequencer Operation, HeliScope Analysis Engine, HeliScope Sample Loader, and HeliScope Control Center