Allegra Orthopaedics Limited, formerly Advanced Surgical Design & Manufacture Limited, is an Australia-based company engaged in the sale, manufacture and design of surgical implants. Its principal product, the Active Knee, is a total knee replacement prosthesis. It is a cementless, metal/polyethylene, cruciate retaining design. The Company manufactures a range of surgical screws, saw blades and kirschner wires (special wires used to secure bone fragments). These supplement its knee products and provide essential components to orthopaedic surgeons. The Company has developed and markets a carpal plate design, used to treat wrist fractures and for the fusion of arthritic and osteoporotic carpal bones. In addition, it has the exclusive license for an electropolishing process on medical cobalt alloy implants which removes embedded polishing particles and surface carbides, improves friction against polyethylene and improves surface tension.