Mighty oaks from little acorns grow; so, too, Oak Ridge National Laboratory (ORNL) nurtures scientific breakthroughs from small ideas. The US center supports basic and applied research in six areas: neutron science, energy, supercomputing, biological systems, advanced materials, and national security. Among its initiatives, ORNL hosts development of advanced materials for energy, sustainable transportation, understanding of climate change, and the ITER international fusion experiment. The lab was established in 1943 as part of the Manhattan Project, known for the atomic bomb. It is funded by the US DOE and operated by UT-Battelle, an alliance between the University of Tennessee and Battelle Memorial Institute.