Tokai Pharmaceuticals, Inc. is a biopharmaceutical company. The Company is focused on developing therapies for the treatment of prostate cancer and other hormonally-driven diseases. The Company’s drug candidate, Galeterone, is a multi-targeted, oral small molecule drug candidate for the treatment of prostate cancer that disrupts androgen receptor signaling through three mechanisms of action. Galeterone acts by disrupting the androgen receptor signaling pathway, which is a pathway that drives prostate cancer growth. The Company has a drug discovery program, ARDA (Androgen Receptor Modulation Optimized for Response). ARDA is focused on the identification and evaluation of compounds with potent androgen receptor degradation activity targeted to patients with androgen receptor signaling diseases, including prostate cancer.