NxStage Medical, Inc. (NxStage) is a medical device company. The Company develops, manufactures and markets systems for the treatment of kidney failure, fluid overload and related blood treatments and procedures. The Company's primary product, the NxStage System One (System One), is a small, portable hemodialysis system designed to provide physicians and patients flexibility in the way hemodialysis therapy is prescribed and delivered. The System One is suited for home hemodialysis and a range of dialysis therapies, including more frequent, or daily, dialysis. The System One is cleared by the United States Food and Drug Administration (FDA) for home hemodialysis, as well as hospital and clinic-based dialysis. The Company also sells needles and blood tubing sets primarily to dialysis clinics for the treatment of end stage renal disease (ESRD).