Integra LifeSciences Holdings Corporation (Integra) is a medical technology company. The Company offers solutions, including regenerative technologies, specialty surgical solutions, orthopedics and tissue technologies, and spine hardware and orthobiologics. The Company through its technology platform is engaged in the repair and regeneration of tissue with engineered collagen devices. The Company has developed product lines for applications ranging from burn and deep tissue wounds to regeneration of dura mater in the brain and repair of nerve and tendon. The Company manufactures and sells its products in five business segments: U.S. Neurosurgery, U.S. Extremities, U.S. Instruments, U.S. Spine and Other, and International.