Proteostasis Therapeutics Inc  

(Public, NASDAQ:PTI)   Watch this stock  
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Feb 11 - Close
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Range     -
52 week     -
Open     -
Vol. 0.00
Mkt cap 110.96M
P/E     -
Div/yield     -
EPS -0.16
Shares 16.71M
Beta     -
Inst. own     -

Key stats and ratios

Q3 (Sep '15) 2014
Net profit margin -601.89% -306.25%
Operating margin -581.02% -304.52%
EBITD margin - -296.23%
Return on average assets -160.86% -166.05%
Return on average equity - -
Employees 42 -
CDP Score - -


200 Technology Sq
CAMBRIDGE, MA 02139-3578
United States - Map
+1-617-2250096 (Phone)
+1-302-6365454 (Fax)

External links

Analyst Estimates - MarketWatch
SEC Filings - EDGAR Online
Major Holders - MSN Money


Proteostasis Therapeutics, Inc. is a United States-based biopharmaceutical company developing small molecule therapeutics to treat diseases caused by defects in protein processing. The Company identifies selective drug candidates that modulate the proteostasis imbalance in the cell by combining the Disease-Relevant Translation, DRT platform, which is a phenotypic screening approach based on the use of functionally pertinent cellular assays and disease relevant models. It is focused on developing a triple combination therapy for cystic fibrosis. It is focused on researching therapeutic strategies for modulating the unfolded protein response. It is focused on researching Usp14 inhibitors to manage the clearance of aggregation-prone proteins, such as tau in Alzheimer's disease and others. The Proteostasis Network consists of over 1,000 proteins organized into pathways. Its DRT platform combines genomics, proteomics and functional assays with medicinal chemistry and systems biology.

Officers and directors

Christopher K Mirabelli Chairman of the Board
Age: 60
Bio & Compensation  - Reuters
Meenu Chhabra President, Chief Executive Officer, Director
Bio & Compensation  - Reuters
Po-Shun Lee M.D. Executive Vice President, Chief Medical Officer
Bio & Compensation  - Reuters
Benito Munoz Senior Vice President - Drug Discovery
Bio & Compensation  - Reuters
Janet L. Smart Vice President - Intellectual Property & Legal Affaris
Bio & Compensation  - Reuters