Proteostasis Therapeutics Inc  

(Public, NASDAQ:PTI)   Watch this stock  
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-1.49 (-9.14%)
Real-time:   2:51PM EST
NASDAQ real-time data - Disclaimer
Currency in USD
Range 14.76 - 16.67
52 week 5.35 - 20.63
Open 16.53
Vol / Avg. 79,139.00/90,832.00
Mkt cap 378.73M
P/E     -
Div/yield     -
EPS -2.30
Shares 24.96M
Beta     -
Inst. own 78%

Key stats and ratios

Q3 (Sep '16) 2015
Net profit margin -628.05% -580.71%
Operating margin -627.93% -568.97%
EBITD margin - -562.66%
Return on average assets -58.17% -164.35%
Return on average equity -71.65% -
Employees 42 -
CDP Score - -


200 Technology Sq Fl 4
CAMBRIDGE, MA 02139-3578
United States - Map
+1-617-2250096 (Phone)
+1-302-6365454 (Fax)

Website links

External links

Analyst Estimates - MarketWatch
SEC Filings - EDGAR Online
Major Holders - MSN Money


Proteostasis Therapeutics, Inc. is a biopharmaceutical company. The Company is engaged in discovery and development of therapeutics that treat diseases caused by an imbalance in the proteostasis network, a set of pathways that control protein biosynthesis, folding, trafficking and clearance. It has developed the Disease Relevant Translation (DRT) technology platform, a drug screening approach for identifying highly translatable therapeutics based on predictive and functionally pertinent phenotypic assays and disease relevant models. Using this platform, it has identified a new class of small molecules, amplifiers that modulate proteins in the proteostasis network. It is developing and intend to commercialize its lead amplifier of CFTR protein, PTI-428, to improve CFTR protein function. It also focuses on developing PTI-NC-733, PTI-130, Usp14 program and unfolded protein response (UPR) program. PTI-130 is a small molecule amplifier.

Officers and directors

M. James Barrett Ph.D. Chairman of the Board
Bio & Compensation  - Reuters
Meenu Chhabra President, Chief Executive Officer, Director
Bio & Compensation  - Reuters
Po-Shun Lee M.D. Executive Vice President, Chief Medical Officer
Bio & Compensation  - Reuters
Brett R. Hagen Principal Accounting Officer, Controller
Age: 43
Bio & Compensation  - Reuters
Janet L. Smart Vice President - Intellectual Property & Legal Affaris
Bio & Compensation  - Reuters