BELLUS Health Inc. (BELLUS Health) is focused on developing drugs for rare diseases, starting with conditions that affect the kidneys. The lead program is KIACTA, a drug candidate in a Phase III Confirmatory Study for the treatment of AA amyloidosis, a rare disease resulting in renal dysfunction that often leads to dialysis and death. KIACTA is also being developed as a treatment in a second indication called sarcoidosis, a rare inflammatory condition that affects the lungs. In addition, BELLUS Health is developing Shigamab, an antibody treatment for hemolytic uremic syndrome caused by Shiga toxin-producing E. coli (sHUS). BELLUS Health�s pipeline also includes a research-stage project for the treatment of AL amyloidosis, a rare disease in which amyloid protein builds up and causes dysfunction in various parts of the body, including the kidneys, heart, liver and peripheral nerves.