CA1308948C - Topography measuring apparatus - Google Patents

Topography measuring apparatus

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Publication number
CA1308948C
CA1308948C CA000581517A CA581517A CA1308948C CA 1308948 C CA1308948 C CA 1308948C CA 000581517 A CA000581517 A CA 000581517A CA 581517 A CA581517 A CA 581517A CA 1308948 C CA1308948 C CA 1308948C
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CA
Canada
Prior art keywords
measured
photodetector
contour
optical
light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000581517A
Other languages
French (fr)
Inventor
Paul R. Yoder, Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AMO Manufacturing USA LLC
Original Assignee
Visx Inc
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Filing date
Publication date
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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B11/00Measuring arrangements characterised by the use of optical techniques
    • G01B11/24Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures
    • G01B11/255Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures for measuring radius of curvature
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/107Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining the shape or measuring the curvature of the cornea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14Arrangements specially adapted for eye photography
    • A61B3/15Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing
    • A61B3/152Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing for aligning

Abstract

ABSTRACT OF THE INVENTION

A contour measuring apparatus and method of using the apparatus is disclosed to measure the three-dimensional contour of a surface. A multi-point light source directs a plurality of light beams onto the surface to be measured. The light beams are reflected through a lens onto a photodetector to produce electro-optically measurable optical images. A structure is provided to determine the local radius of curvature of the surface at each desired point of incidence of individual light beams and the three-dimensional surface contour of the surface being measured. A
calibration device is provided to reduce instrument errors of the apparatus. The calibration device includes a calibration surface with a known contour to be positioned in substitution of the surface being measured. The apparatus includes a structure to sequentially determine and store a memory of the location of the calibration surface and to compare the reflection of the light from the calibration surface as well as the surface being measured to determine the contour of the surface being measured.

Description

u ~ 1 308~4~

While the invention is subject to a wide range of applications, it is particularly suited to measure the three-dimensional contour of a surface.
In particular, this invention relates to that aspect of ophthalmic diagnosis which is concerned with measurement of the three-dimensional contour of the anterior surface of the cornea. This measurement discloses abnormalities in the cornea which may have deleterious effects upon vision or quantifies progress of ophthalmic surgery, such as laser-aided radial keratotomy or laser ablation of the external surface of the cornea with penetration into the stroma and volumetric removal of tissue, whereby the external corneal surface is characterized by a sculptured, new curvature having improved optical properties.

Devices variously called corneascopes or keratometers have been developed for topographic analysis of the cornea. Such devices have found acceptance as means for measuring corneal curvature in preparation for prescribing a contact lens to be worn over the measured cornea to reduce certain visual defects, or for use in other ophthalmic applications. The prior art for these devices entails photographic (as in U.S. Patent 3,797,921, Kilmer, et al.) or electro-optical (see U.S. Patent 4,572,628, Nohda) recording of cornea-reflected ' ~ 2 1 3 0 ~ g images of illuminated objects comprising several concentric rings, or multiple discrete light sources arranged in the form of concentric rings, on a flat surface normal to the optical system axis or on a concave surface symmetrically disposed with respect to that axis. If the cornea is spherical, the reflected images of these ring-shaped objects are equally spaced, continuous or intermittent, concentric ring-shaped patterns. If the cornea surface is rotationally symmetrical but not spherical, the resultant ring images are less equally spaced; the inequality of spacing is thus a measure of nonsphericity of the cornea surface. If the cornea surface is astigmatic, as is frequently the case, the ring-shaped images reflected by that cornea will appear elliptical, and the eccentricity of the pattern is related to the change in curvature of the cornea surface between various sectional meridians. This eccentricity, and hence the 1 20 astigmatism of the surface, can be measured by careful analysis of an image of the ring pattern.
The orientation of the major and minor axes of the elliptical pattern relative to the eye indicates the orientation of the principal axes of the observed astigmatism. If the cornea has been warped or distorted by injury, by disease or by prior surgical procedures, such as radial keratotomy or imperfect closure of incisions made during cataract or other surgery, the magnitudes of these surface defects can also be measured.

~ ~ 3 1 3(~9~

In each of these described cases, the desired end result is (1) a tabular or graphic representation of the surface optical power (in units of diopters) at various points over the visually used, central portion of the cornea (typically 3 to 7 mm in diameter), and (2) computed average values for these parameters over the area of interest. Because of the tendency for the eye to - become astigmatic, or non-rotationally symmetrical, comparisons of surface radius or power are frequently made for various azimuthal meridians about the visual axis. Instrument errors introduced by the apparatus and systematic or random errors introduced by the method of use are preferably minimized in order to minimize the overall measurement error. Prior art devices for accomplishing these measurements have been found lacking in regard to one or more of the following attributes: accuracy, ease of use, and time required to obtain the desired tabular or graphical output. None of these devices is compatible with use in situ and in close temporal alignment with surgical laser sculpturing of the cornea to produce desired net curvature changes to improve vision.

1 3 ~!~ 3 ~ ~ ~

The present lnvention provides a method and means for improving the accuracy and speed with which the topography of the anterior surface of the cornea can be measured. The contour measuring apparatus described herein incorporates a self-calibration capability which ensures that the instrument error of the measurement is small.
The preferred apparatus disclosed herein has a simple means for achieving proper location and orientation of the eye under test with respect to the diagnostic apparatus.
Also, this apparatus makes possible the measurement of corneal radius, and thus optical power, at individual small, localized areas on the surface.
The contour measuring apparatus disclosed herein provides an in situ means for observing the exterior of the eye and for measuring the topography of the cornea surface at selected times before, during and after performance of surgical procedures such as are taught by pending L'Esperance, Jr. U.S. patent applications including Serial No. 691,923, Serial No. 748,358, Serial No. 891,169 and Serial No. 891,285. Those applications cover the ablation of the cornea with penetration into the stroma and volumetric removal of corneal tissue through controlled application of radiation from an ultraviolet laser, or similar procedures utilizing radiation of longer wavelength such as an infrared laser operating at about 2.9 micrometers.

1 3C~4~

The apparatus disclosed herein analyzes the pattern of images of an array of light points specularly reflected from the surface being measured such as the convex surface formed by a cornea being measured for diagnostic purposes or, for example, a spherical ball of known radius of curvature used for apparatus calibration purposes. In a preferred embodiment, the apparatus is capable of interfacing directly with apparatus as described by Telfair, et al, in pending patent applications serial No. 938,633 and serial No.
009,724, so as to permit diagnostic evaluation of a given cornea in conjunction with surgical sculpturing of the same cornea with laser radiation to improve its optical properties.
According to one aspect of the invention, a contour measuring apparatus for measuring the three-dimensional contour of a surface comprises a multi point light source to direct a plurality of individual light beams onto the surface being measured; a photodetector for producing electro-optically measurable optical images; lens means disposed between said surface being measured and said photodetector to focus the reflected beams of light from the surface being measured onto the photodetector to form the measurable optical images; a telecentric aperture stop positioned between said lens means and said photo-detector substantially at a focal point of said lens means; means in electrical communication with said photo-detector for 1 303~4~
- 5a determining both the local radius of curvature of the measured surface at each desired point of incidence of the individual light beams and the three-dimensional surface contours of the surface; calibration means for reducing instrument errors of the apparatus, said calibration means including a calibration surface with a known contour to be positioned in substitution of said surface being measured;
means to sequentially determine and store in memory the location on said calibration surface of each image of each individual light point; and means to determine the contour of the surface being measured from a differential evaluation of the reflection of each light point image from the surface being measured in comparison to the reflection of each light point image from the calibration surface with a known contour.
According to a further aspect of the invention, a method of measuring a three-dimensional contour of a surface comprises the steps of directing a plurality of individual light beams onto a surface being measured; focusing the reflected beams of light from the measured surface onto a photodetector to form measurable optical images; determining both the local radius of curvature of the measured surface at each desired point of incidence of the individual light beams and the three-dimensional surface contours of the surface; prior to the step of directing a plurality of individual light beams, reducing the instrument errors of - 5b - l 30 ~4~
the apparatus using the following steps: substituting the surface to be measured with a calibration surface having a known contour; sequentially determining and storing in memory the location on the calibration surface of each image of individual light points from the plurality of individual light beams directed onto the calibration surface; and determining the contour of the surface being measured from a differential evaluation of the reflection of each light point image from the surface being measured in comparison to the reflection of each light point image from the calibrated surface.
According to another aspect of the invention, a contour measuring apparatus to measure the three-dimensional contour of a surface comprises a contour measuring structure having a multi-point light source to direct a plurality of individual light beams each corresponding to individual light points of the multi-point light source onto the surface being measured; a photodetector receiving reflections of the individual light beams from said surface for generating electrical output signals corresponding to electro-optically measurable optical images, each of said images corresponding to one of said light points; means disposed between said surface being measured and said photodetector for focusing the reflected beams of light from the surface being measured onto the photodetector to form the measurable optical images; said focusing means 1 30~9~
- 5c comprising a lens centered on an optical axis extending through said contour measuring structure; means between the focusing means and said photodetector for limiting the cone angle of the rays of the individual light beams reflected from the surface whereby each of said reflected rays closely approximates a telecentric principal ray corresponding to a light point; said photodetector including a photodetector surface into which said reflected light beams are focused, said photodetector surface being disposed transverse to said optical axis; means receiving said electrical output signals from said photodetector for measuring the position of each optical image in the photodetector and for determining both the local radius of curvature of the measured surface at each point of incidence of the individual corresponding light beams and the average radius of curvature of the measured surface; and calibration means for reducing instrument errors of the apparatus, said calibration means including: a calibration surface with a known contour to be positioned in substitution of said surface being measured;
and means for determining the magnification of said lens whereby the curvature of the measured surface can be determined.
According to still another aspect of the invention, a method of measuring a surface comprises the steps of directing a plurality of individual light beams each corresponding to individual light points of a multi-point 1 3r)8~4~3 - 5d light source onto the surface being measured; providing a photodetector for generating electrical output signals corresponding to electro-optically measurable optical images; focusing the reflected beams of light from the measured surface onto the photodetector to form measurable optical images, each of said images corresponding to one of each,light points, said step of focusing the reflected beams of light including the steps of: disposing a lens transverse to an optical axis extending from said surface being measured to said photodetector; directing the beams of light through said lens; limiting the cone angle of the reflected beams of light whereby each individual beam closely approximates a telecentric principal ray of individual beam; measuring the position of each optical image on the photodetector from the electrical output signals of the photodetector for determining both the local radius of curvature of the measured surface at each point of incidence of the individual light beams and average radius of curvature of the measured surface; and prior to the step of determining the radius of curvature of the measured surface, reducing the instrument errors of the apparatus using the following steps: substituting the surface to be measured with a calibration surface having a known contour; and determining the magnification of the lens whereby the curvature of the measured surface can be determined.

~ 5e - l 3~4~
According to yet another aspect of the inventlon, a contour measuring apparatus to measure the three-dimensional contour of a surface comprises a multi-point light source to direct a plurality of individual light beams each corresponding to individual light points of the multi-point light source onto the surface being measured; a photodetector receiving reflections of the individual light beams from the measured surface for generating electrical output signals corresponding to electro-optically measurable optical images, each of said images corresponding to one of said light points; means disposed between said surface being measured and said photodetector for focusing the reflected beams of light from the surface being measured onto the photodetector to form the measurable optical images; means between the focusing means and said photodetector for controlling the size of the area on the measured surface from which the beams of light are reflected; means receiving said electrical output signals from said photodetector for measuring the position of each optical image in the photodetector and for determining both the local raaius of curvature of the measured surface at each point of incidence of the individual corresponding light beams and the average radius of curvature of the measured surface.
According to a further aspect of the invention, a method of measuring the three-dimensional contour of a surface comprises the steps of directing a plurality of individual _ 5f - l 30~9~
light beams each corresponding to individual light points of a multi-point light source onto the surface being measured;
reflecting the individual light beams from the measured surface onto a photodetector for generating electrical output signals corresponding to electro-optically measurable optical images, each of said images corresponding to one of said light points; focusing the reflected beams of light from the surface being measured onto the photodetector to form the measurable optical images; controlling the size of the area on the measured surface from which the beams of light are reflected; measuring the position of each optical image in the photodetector; and determining both the local radius of curvature of the measured surface at each point of incidence of the individual corresponding light beams and the average radius of curvature of the measured surface.

1 3 r' ~

The invention will be illustratively described for preferred and other embodiments, in conjunction with the accompanying drawings, in which:

FIGURE 1 is a simplified block diagram to show the functional relationships of generalized optical, mechanical and electrical components of topography-measuring apparatus of the invention;

FIGURE 2 is a diagram of principal optical components of FIGURE 1, including an array of multiple light sources;

FIGURE 3 is a diagram showing certain geometric relationships that are pertinent to the optical arrangement of FIGURE 2;

FIGURE 4A is a simplified optical diagram of apparatus of FIGURE 1, arranged in a calibrating mode, and FIGURE 4B is a similar but fragmentary diagram to illustrate a modification;

FIGURES 5A and 5B are respectively front-end and longitudinal-section views, to an enlarged scale, for a calibration element in FIGURE 4B, and FIGUR~ 5C is a modified calibration element.

' ' 7 1 30~q~

FIGURE 6 is a representation, in a radial-plane projection, for an illustrative distribution of multiple light sources in the array of FIGURE 2;

FIGURE 7 is a diagram to illustrate use of the invention in conjunction with apparatus for surgical sculpture of the cornea;

FIGURE 8 is an optical diagram to show another application of the invention;

FIGURE 9 is a further development of FIGURE 4A
incorporating means to measure alignment of the eye calibration device relative to the diagnostic apparatus;

FIGURE 10 shows the typical appearance of the visual field of the focus alignment sensing means in the calibration mode;

FIGURE 11 shows the typical appearance of the visual field of the focus alignment sensing means in the operational mode; and FIGURE 12 is a simplified diagram relating the focus alignment sensing means to a laser sculpturing apparatus.

8 1 3!~9ar3 ,J

A contour measuring apparatus 9 to measure the three-dimensional contour of a surface 13 is disclosed. The apparatus 9 includes a multi-point light source 11 to direct a plurality of individual light beams 10 onto the surface 13. A photodetector 19 produces electro-optically measurable optical images. A lens 15 is disposed between the surface 13 and the photodetector 19 to focus the reflected beams of light 14 from the surface being measured 13 onto the photodetector 19 to form the measurable optical images. A signal switch 21, a frame grabber 23, and computer means 24 are in electrical communication with said photo-detector 19 for determining both the local radius of curvature of the surface 13 at each desired point of incidence of the individual light beams and the three-dimensional contours of the surface 13. A calibration device 70 is provided to reduce instrument errors of the apparatus 9. The calibration device 70 includes a calibration surface 72 with a known contour to be positioned in substitution of the surface 13 being measured. Components 21 and 23 sequentially determine and store in memory the location on said calibration surface 71 of each image of individual light points. Means 24 further determine the contour of the surface 13 being measured from a differential evaluation of the reflection of each 9 1 30`3q48 light point image from the surface 13 being measured in comparison to the reflection of each light point image from the calibration surface 71 with a known contour.

In FIGURE 1, the invention is shown as an apparatus 9 for producing and interpreting images : reflected from a surface under test. An array 11 of light sources is activated by a power supply 12, and multiple diverging light beams 10 from the array are intercepted by a contoured surface 13 under test;
contoured surface 13 acts as a mirror to reflect light beams 14 into a lens 15 which, in turn, focuses those light beams 16 through an aperture or iris 17. The beams 18 emerging from aperture 17 are then focused onto the sensitive surface of a photo-detecting means 19. Electrical output signals 20 generated by means 19 are directed by a signal switch 21 to a frame grabber 23 which produces a time-sequenced series of electrical signals represent- ative of the spatial distribution of energy in the image formed by lens 15. These electrical signals can be displayed as a real time video image in a display apparatus 22.
Alternatively or in addition, the electrical signals can be stored in digital form by a frame grabber 23, for further analysis by a computer 24 and/or for supply to display means 22 or print-out means 25.
Special algorithms stored in computer 24 permit 1 3 ~J ~ t ~ ~

,!

computation of the radius of curvature, and hence of the optical power, of contoured surface 13 at the point of incidence on said surface of the beam from any one light source in the array 11. Means 26 allows the optical alignment o the surface 13 relative to the axis of lens 15 to be measured.

Further detail as to function of the involved optical system of the invention is shown in FIGURE
2, wherein the array 11 comprises a plurality of individual light emitting diodes (LEDS) disposed on a nominally spherical surface llA, of known contour, having its center Cl on the optical axis 27 of the system. Preferably, the surface llA is nominally spherical; however, it is within the terms of the invention for the surface llA to be of any desired shape. Although the array 11 of light sources preferably is comprised of LEDs, it is also within the terms of the present invention to construct the array 11 of any type of light sources, such as a plurality of fiber optics. The center C2 of a convex surface 28, equivalent to surface 13 in FIGURE 1, under test also lies on the axis 27 but does not necessarily coincide with Cl. One of the beams 10 is the divergent beam 29 from a typical LED
30 which is redirected, upon reflection from surface 28, as a more divergent beam 31 of the beams 14 into the aperture of a lens 32. The lens 32 is ~ !J ~3 (3 ~ ~

; preferably centered on axis 27 and located at an appropriate distance downstream from surface 28.
Through the image-forming properties of lens 32, an image of the typical LED 30 is produced at some point on the photocathode 33 of a conventional photo-detecting device 19 which may be a vidicon-type image tube; alternatively, device 19 may be an array of discrete detectors such as a charge coupled device (CCD). Typically, the photocathode of such an image tube or array would have usable aperture dimensions of about 6.6 x 8.8 mm and would be sensitive to the visible light emitted by the light source 11. Because of the inherent rotational : symmetry of the various optical and electro-optical components about the axis 27, the image of the entire array 11 typically lies within a circle inscribed within the rectangular usable aperture of the photocathode. It should be noted that the photodetector means 19 is in no way limited to the indicated light source or particular dimensions, in that larger or smaller devices of like or different nature may be accommodated by selection of the specific type of photodetector 19 and by appropriately scaling the size of the image.

A feature of the invention is the inclusion of an aperture such as iris 34 located on the axis 27, offset from lens 32 at a distance substantially equal to the back focal length (BFL) of the lens 32, 12 1 3!'"9~

thus placing iris 34 at the focal point of the lens.
The opening of iris 34 is constrained to always be small enough that it, rather than the aperture of lens 32, determines the angular size of the conical beam 31' of beam 18. The iris 34 acts as the aperture stop of the system and controls the cone angle of the individual beams 14, 16, 18, 31', 31 and 29 as well as the size of the area ~a" on test surface 28 which contributes light from the typical LED 30 to the corresponding image point on photodetecting means 19. Since iris 34 is located at the focal point of lens 32, light rays 31'A
passing centrally through the iris, at any angle "b" with respect to axis 27, must propagate parallel to axis 27 in the space between test surface 28 and lens 32. These rays 31'A, called principal rays, are then said to be telecentric in the object space of lens 32, and the aperture stop 34, i.e., the iris, is a telecentric stop. The opening in the iris 34 can be small since the LEDs are intrinsically very bright and the image sensor is very sensitive to incident light. All the rays in the beam from a given LED are therefore physically near each other and all closely approximate the path of the appropriate principal ray.

The fact that the principal rays from all LEDs in the array 11 travel parallel to axis 27, after reflecting from surface 28, allows use of a simple . 13 1 30~48 mathematical process to independently compute the average radius of surface 28 over each of the small localized areas of dimension ~a~ centered about the intercept points of the principal rays on surface 28.

FIGURE 3 illustrates the applicable geometrical condition. It may be noted that surface 28 is located at an axial distance dl from surface llA and that the principal ray 29 from a typical LED 30 (here assumed to be a point source of light at P2) intercepts surface 28 at a height Yl from the axis 27 and proceeds to lens 32 as ray 29' parallel to - said axis. Ray 29' becomes ray 29" beyond lens 32 and passes through focal point F en route to point P3 at the image plane within the image sensor 19.
The radial distance Y3 of P3 from the axis 27 is related to Yl by the lateral magnification ratio inherent in the lens 32. A method for determining this magnification ratio is described later in this description.
The law of reflection at an optical surface requires the path of ray 29 from P2 to Pl to be such that (a) its extension (dashed line) through surface 28 and (b) the extension (dashed line) of reflected ray 29' are both tangent (at P5 and P4~
. respectively) to a circle constructed concentric with surface 28. The perpendicular distance from tangent point P4 to center Cl thus equals the 1 30~948 perpendicular distance from tangent point Ps to that same center. For convenience, both of these distances will be referred to as ~r~, which may be expressed:
A Xc + B Yc + C
r = ; (1) ~/A2 + B2 where:
A = Yl - Y2' B = X2 ~ Xl~
and C = X2 Yl - Xl Y2 and Xc~ Yc are the coordinates of center Cl measured from X and Y axes through origin "0" at surface llA.
Since ray 29' is parallel to axis 27, as shown in FIGURE 3, r also equals Yl. In the nominal case, Yc = , since Cl lies on the X axis.

As mentioned in connection with FIGURE 1, the image on the photodetector 19 can be analyzed mathematically. A frame of multiple LED images can be stored digitally by frame grabber 23 for subsequent analysis in computer 24 and display at 22. The results of the analysis can be tabulated and various representa- tions of the surface contour printed by printer 25. The information needed to compute the radius of curvature of the surface 28 at various points comprises the radial distance Y3 for each of the images of the LEDs in array 11. Since 1 30~948 the magni-fication ratio of lens 32 can be determined, the corresponding heights Yl can be computed.

When the coordinates of P2 and of Cl and the Y
coordinate of Pl are known, the unique value of X
can be computed from the quadratic equation:
.
- E + ~ E2 - 4 D G

; Xl = ; (2) : 2 D
where:
D = A (2 Yl - A), E = 2 A (A Xc - Xc Yl ~ X2 Yl)~
and G A (yl2 - Xc2) + 2 A Xc X2 Yl Once Xl and Yl are known, the radius Rl at P
can be computed from the expression:
Rl = ~ yl2 + X12 (3) In general, the axial distance dl between the surfaces llA and 28 can be measured by standard means. Hence, Xc = dl + Rl 1 30p~q~r+~

Since radius Rl is initially unknown, an iterative procedure may be used wherein a reasonable : value for Rl is chosen and substitu~ed into Equation 4 to give a first approximation for Xc. Then, values of the coefficients A, D, E and G are determined, and a first approximation value for R
is computed from Equation 3. Successive computations give progressively more precise values : for Rl; the iterative process is stopped when the ; 10 desired precision is achieved.

This mathematical process is repeated for each LED image, and the local radius of the cornea is computed, for each of the various locations intercepted by narrow beams from the individual LEDs. The average radius of the surface, the extreme long and short radii of said surface, the dioptric equivalent of each of these radii, and the difference in average optical powers in the directions of the principal astigmatic meridians, as well as the azimuthal orientations of said meridians, can then be determined using methods of analytic geometry.

The location for each luminous point P2 must be known in order for the last described computational process to be used. These locations can be determined by directly measuring the coordinates of each LED source of the array 11. Alternatively, 1 303'`~4~

and preferably, this location can be determined with a calibration device 70. The calibration device includes a surface 71 of known contour. This surface 71 may comprise a spherical surface. A
preferred technique of performing the calibration of apparatus 35 is accomplished by inserting a substantially spherical member 72 having a spherical surface 28' of precisely known radius into the apparatus 36. The spherical member 72 is located with its center on axis 27 at distance dl from surface llA, as shown in FIGURE 4A. The spherical ; member 72 can be positioned in the axial direction and in two transverse directions with respect to topography measuring apparatus 35, using adjusting means 36 which may typically comprise a three-dimensional translation stage. Proper centering is indicated by equality of the dimensions Sl and S2 to each other in the plane of FIGURE 4A, as well as in the plane which includes axis 27 and is perpendicular to FIGURE 4A. Adjustments to locate surface 28' at the specified distance dl from the spherical LED locus (surface 11) can be accomplished by the linear adjustment means of fixture 36. Once initially aligned, a conical seat 37 and a spring-loaded clamping means 38 provide a convenient andreliable means for relocating the spherical member 72 at its prescribed location, whenever calibration is to be rechecked.

1 3~8~4~

In order to use the reflecting spherical member 72 as a calibration means, or to use the corneascope-type apparatus 35 to determine the topography of a cornea under test, the magnification of lens 32 must be known. This parameter can be measured as indicated in FIGURE 4B, where a fiducial target member 39 is inserted in the adjustable fixture means 36 against the seat 37 at an axial distance d3 from surface llA. Then, a determination is made of the size of the corresponding image of the surface of target 39 on photodetecting ~eans 19.
The ratio of the measured image dimension to the actual object dimension is the magnification of the optical system, or lens 32. Typically, the lS absolute value of said magnification is about 0.4 to 0.6 times.
-The ideal value of d3 is slightly greater thandl since target surface 41 should be located essentially at the same distance from lens 32 as the image of the LEDs reflected by convex surface 28.
The latter image is virtual and located at a distance behind said surface 28 given by the expression:

d2 = (Rl dl) / (2 dl + Rl) (5) Typically, for dl = 100 mm and Rl = 8 mm, d2 = 4.2 mm and d3 = dl + d2 = 104.2 mm. This location of 19 1 30~94~

the fiducial target surface 41 ensures that the images at the photodetector 19 of the LEDs and of the fiducial target will both be in focus.

By virtue of the telecentric nature of the optical system in object space of the lens 32, the magnification is essentially constant for moderate variations (of the order of a few millimeters) in the distance dl. Since the location of a given point on the photosensitive surface of photodetecting means 19 is generally derived by measuring the distance of the point in units of pixel (picture element) widths horizontally and pixel heights vertically from some reference (such as a corner of the rectangular raster), and since the dimensions of a typical pixel may be different in these directions, the linear magnifications in these two directions may differ from each other.
The measured values would generally be stored in computer memory for use at appropriate times during the subsequent computations.

The fiducial target 39 may be any of a variety of types such as two or more separated marks 73 so designed as to reflect or absorb light thereby becoming visible due to contrast against the background formed by the underlying surface of the target substrate. Since magnification can vary azimuthally about the axis 27 of an optical system, ~ 30~48 it is advisable to have dual fiducial marks on each of at least two mutually perpendicular intersecting diameters. In a preferred simple embodiment, a circular fiducial ring 40 is scribed or otherwise marked on the fiducial target substrate 39. The - ring 40 is then located so as to be concentric with the axis 27, as indicated in FIGURES 5A and 5B. The fiducial ring 40 may be generated on a flattened surface 41 of an otherwise spherical target body 72, e.g., a flat locally ground on a tooling or bearing ball. It can then easily be seated against the conical seat 37 of the adjusting means 36 of FIGURE
4B, thereby assuring proper centering with respect to the spherical LED locus 11 and to the axis 27.
The depth of material removed in generating the flattened surface of the fiducial target on a sphere of radius Rl is equal to the aforementioned dimension d2-As indicated in FIGURE 5C, the functions of the spherical reflecting calibration surface 28' and of the fiducial target 39 can be combined as at 39B by suitably machining a spherical ball.

In a calibrating use, the LED sources are illuminated and the corresponding locations of the images at the image sensor 19 determined in the same manner as for the corneal reflections previously described. After converting these images to ' ' 21 1 30~4~

corresponding heights Yl, the actual X and Y
coordinates of the points P2 for all the LEDs can be computed. This is the self-calibration process referred to as one object of the invention.

The method for accomplishing this computation also relies upon the law of reflection at surface 28 and mathematical expressions derived from analytic geometry, as follows:
Y24 + I Y23 + J Y22 + L Y2 + M = 0; (6) where:
H = 4 K22 + K32 I = (4 K2 K3 R2 + 2 K3 K4 + 8 Kl K2) / H
J = (4 K12 + 4 Kl K3 R2 + 4 K2 K4 R2 + 2 K3 R5 + K42) / H
L = (4 Kl K4 R2 + 4 K2 Ks R2 + 2 K4 ~5) / H
M = (4 Kl Ks R2 + Ks2) / H
Kl = (XC - Xl) yl2 K2 = ( Xl - XC ) Yl K3 = yl2 - XC2 + 2 Xc Xl - X12 K4 = 2 (Xc2 Yl - Xc Xl Yl ~ Yl ) Ks = Y14 + X12 yl2 - Xc2 yl2 Once the Y2 values have been computed, it is a simple matter to compute the corresponding X2 values from the expression:
; X2 = ~R22 _ y22 (7 22 1 3'~-'`3~4~

where R2 is the known radius of curvature of the spherical locus of all the LED sources (i.e., points P2 ) -This feature of the present invention allows the corneascope to be calibrated thereby negating the deleterious effects of unavoidable manufacturing uncertainties in locations of the LED light sources used in calculating the corneal radius. By accomplishing this calibration periodically, instrument errors can be reduced to a minimum, and the resultant precision in measuring radius of curvature and dioptric power at a given point on the cornea is improved significantly over that achieved with prior art methods and apparatus.

In order to provide radius information at an adequate number of points over the circular area of interest on the cornea (typically of 5 to 7 millimeters diameter, centered on the optical axis of the eye) for ophthalmic diagnosis purposes, the light-source array 11 preferably includes many individual point light sources. FIGURE 6 illustrates such an array comprising 64 LEDs arranged as 4 rows of 16 LEDs each crossing the aperture of the array, along meridians oriented at 23 1 30~'~4~

45-degree intervals of azimuthal angle. The LEDs are located on a concave spherical surface to minimize the overall size of the apparatus while providing the required angular inclination of narrow beams from the individual sources to the subsequent optical elements in the system. It will be understood that additional light sources can be included along each meridian in the array, or additional meridians can be added in total or in part, if more information about the corneal contour is needed; conversely, fewer light sources may be used if less information is needed. In an alternate embodiment, a full complement of many light sources could be installed, but specific geometric groupings of sources could be selected by a suitable switching arrangement (not shown) to fit the need of a particular measurement to be accomplished at any time, thereby reducing the overall time required for processing and analysis of the data.

As was pointed out earlier in this description, the physical aperture diameter of the telecentric stop (iris) 34 can be quite small and yet allow sufficient light to pass through the system to produce detectable images on the photosensing means 19. Calculations pertinent to a particular embodiment of the invention indicate that, for image quality reasons, the image-forming beam should have ~ 3i~'`3~

an effective relative aperture no larger (i.e., no faster) than f/13. This has a secondary effect upon the performance of the image-forming system in that it significantly increases the depth of field for the LEDs and allows sharp images thereof to be formed at all points within the field of view. Some prior art systems used for this purpose have exhibited degraded image sharpness at edges of their field of view due to uncorrected aberrations related to the large effective relative aperture used therein.

The radial distance Y2 indicated for a typical LED in FIGURE 6 corresponds to the Y coordinate of point P2 in FIGURE 3, and it will be noted that radial separations ( Y2) between LEDs along any meridian are not constant. This circumstance reflects the preferred condition of equal radial separations ( Yl) of adjacent incidence points P
for the principal rays on surface 28. If the surface 28 is spherical, the corresponding radial separations of image points in the image plane at photo-detecting means 19 also are equal. While not essential to the function of the apparatus, this equality of image spacing facilitates detection of surface 28 irregularities, including astigmatism, when the composite image of the entire LED array is observed on the display 22 of FIGURE 1 or is shown in hard copy produced by printer 25.

25 1 3 C~J~

In FIGURE 7, the invention is shown in simplified form, interfacing directly (via a fold mirror 42) with laser-sculpturing apparatus 61 of the general type described by Telfair, et al., in patent applications Serial No. 938,633 and Serial No. 009,724. When the fold mirror 42 is removed from the beam, the present corneascope-type topography measuring device can be used to evaluate the contour of the cornea 28 located hear the center of curvature of the array 11. If a beamsplitter is used in lieu of the mirror 42, the diagnostic function can be accomplished in near-real time with laser sculpturing. In either of these events, a synchronizing connection 50 is shown between the sculpturing apparatus 61 and the photosensitive device 19 of the topography measuring apparatus, to assure at least an interlaced separation of sculpturing versus measuring functions in the course of a given surgical procedure.

Inasmuch as the image formed by lens 32 on photo-detecting means 19 is not limited to the specific 5 to 7 millimeter diameter area of interest in diagnostic evaluation of the topography of the cornea, the described apparatus can be used to observe a large portion of the exterior of the eye under magnification, as in a surgical microscope.

As depicted in FIGURE 8, the field of view of the optical system is determined by the angular subtense of the sensitive area 43 on photodetector 19, as measured from the center of the aperture stop 34. Typically, the extent 44 of said field of view at the eye under examination is 12 to 16 millimeters in diameter, depending upon the specific combination of parameters in the design.

The image of the eye is presented in real time to the observing ophthalmologist and to other interested parties via the video subsystem comprising the vidicon or CCD array 19, signal switch 21 and display 22. Illumination of the eye is provided by a light source 45 which will be understood to be a single lamp or a multiplicity of lamps, e.g., room lights. By use of appropriate video components, the display can be presented in monochrome (i.e., black and white) or in true or false color.

Inherent in successful functioning of the invention is establishment of the proper axial distance dl (see FIGURE 3) between the light source 11 and the surface under test 28. Mathematical analysis clearly shows that, in order to achieve +
1/4 diopter precision in corneal refractive power measurements, the dimension dl must be held constant within approximately + 0.25 mm of the design value during calibration and operation.

27 1 3~J~q 48 This level of distance measurement and control can be achieved in a variety of ways. For example, a simple mechanical probe of calibrated length can be extended from the topography measuring apparatus S to just touch the surface 28 at its axial vertex when said surface is at the proper location. The possibility of damaging the test surface with a probe precludes its application to ophthalmic applications. Non-contacting (optical or electro-optical) means such as ones functioning in arangefinding mode in cameras to establish focus or means using inclined projected light beams which superimpose when incident upon the test surface if said surface is located at the proper (precalibrated) axial distance or means which illuminate a multi-element detector array by reflected specular or scattered light can typically be applied here.

A simple, preferred, non-contacting means for focus sensing employs an optical microscope (commonly called a ~telemicroscope") with a long working distance, i.e. the clearance between object observed and the nearest surface of the microscope, so oriented as to allow the surface 28 to be seen in profile from a direction normal to the optical axis of the topography measuring apparatus. By attaching this telemicroscope to the topography measuring apparatus in stable fashion, so its line of sight 28 1 3 n~4 8 does not change location with time, it can be utilized as a fixed reference for focus distance measurement. The telemicroscope can also be used to establish the proper focus distance to either the calibration ball 70 or to the tested surface 28 to ensure applicability of the calibration to the specific test surface evaluation.

FIGURE 9 illustrates schematically one embodiment of the focus alignment sensing device 51, i.e. a telemicroscope, integrated into the corneal topography measuring apparatus 35. In this embodiment, means are provided for the user's eye 53 to observe a view along the axis 27 of the reflected pattern of LED images from surface 28' via beamsplitter 52, lens 54, mirror 55A, and eyepiece 56. Alignment reference is achieved by internal means such as a cross-hair reticle pattern 57 located at the image of the LED pattern. In use during calibration, this optical subsystem allows the surface 28' to be centered vertically and horizontally through action of adjustable fixture 36. In use during measurement of a cornea, this subsystem provides a reference for vertical and horizontal alignment of the vertex of the eye through action of appropriate mechanisms which adjust position of the subject's head and/or eye.

Another feature of the apparatus shown in 29 1 3 nQ~8 FIGURE 9 is the alternate telemicroscope path formed by movement of mirror 55A out of the above-described optical path to a position such as is shown at 55B.
An image of a side view of surface 28' or of the surface under test will then be accessed by means of mirror 58 and lens 59 used in conjunction with the remaining components of the basic telemicroscope.
The appearance of the field of view of said adapted telemicroscope in the focus~measurement mode during calibration is illustrated schematically in FIGURE
10. A similar view showing proper alignment of the eye cornea to the telemicroscope's crosshair pattern is shown in FIGURE 11. It should be noted that it is preferable, but not essential, that the image presented to the operator's eye be erect since this would facilitate use of the device.

FIGURE 12 represents one embodiment of an image-erecting focus alignment measuring telemicroscope means 60 incorporated by mechanical structure, not shown, into a laser sculpturing apparatus 61 which is equipped with a corneal topography measuring apparatus of the type described here.

While the present invention has been described primarily for use in measuring the contour of a cornea, it can also be used to measure the shape of any regular or irregular contoured surface. For - 30 - 13 `3~
example, the invention could be used to measure the contour of optical lenses, mirrors, ball bearings and precision machine parts, to name a few.
It is apparent that there has been provided in accordance with this invention a method and apparatus for measuring the topography of a contoured surface which satisfies the objects, means, and advantages set forth hereinabove. While the invention has been described in combination with the embodiments thereof, it is evident that many alternatives, modifications, and variations will be apparent to those skilled in the art in light of the foregoing description. Accordingly, it is intended to embrace all such alternatives, modifications, and variations as fall within the spirit and broad scope of the appended claims.

Claims (87)

1. A contour measuring apparatus to measure the three-dimensional contour of a surface, comprising:
a multi point light source to direct a plurality of individual light beams onto the surface being measured;
a photodetector for producing electro-optically measurable optical images;
lens means disposed between said surface being measured and said photodetector to focus the reflected beams of light from the surface being measured onto the photodetector to form the measurable optical images;
a telecentric aperture stop positioned between said lens means and said photodetector substantially at a focal point of said lens means;
means in electrical communication with said photodetector for determining both the local radius of curvature of the measured surface at each desired point of incidence of the individual light beams and the three-dimensional surface contours of the surface;
calibration means for reducing instrument errors of the apparatus, said calibration means including a calibration surface with a known contour to be positioned in substitution of said surface being measured;
means to sequentially determine and store in memory the location on said calibration surface of each image of each individual light point; and means to determine the contour of the surface being measured from a differential evaluation of the reflection of each light point image from the surface being measured in comparison to the reflection of each light point image from the calibration surface with a known contour.
2. The apparatus of claim 1 wherein said lens means has an optical axis extending therethrough and said photodetector has a photodetector surface into which said reflected light beams are focused, said photodetector surface being disposed transverse to said optical axis.
3. The apparatus of claim 2 wherein said means to sequentially determine and store include a frame grabber.
4. The apparatus of claim 3 wherein said means to determine the contour includes computer means.
5. The apparatus of claim 4 in which the telecentric stop has a small physical aperture which limits the size of light beams reflected from the surface being measured to produce uniformly sharp images of the reflected beams on the photodetector surface.
6. The apparatus of claim 5 wherein said individual light points comprise an array of individual LEDs.
7. The apparatus of claim 6 wherein said calibration surface is substantially spherical.
8. The apparatus of claim 7 wherein the spherical calibration surface is polished.
9. The apparatus of claim 1 wherein said calibration means includes means for independently adjusting the position of the calibration surface in each of three orthogonally related axes of displacement to facilitate mutual alignment of the calibration and contour measuring components of the apparatus.
10. The apparatus of claim 7 wherein said calibration means includes means for independently adjusting the position of the calibration surface in each of three orthogonally related axes of displacement to facilitate mutual alignment of the calibrating and contour measuring components of the apparatus.
11. The apparatus of claim 10 further including means to support a spherical surface.
12. The apparatus of claim 6 further including selectively operable means associated with said computer means to select a particular group of LED images for analysis and evaluation to the exclusion of other groups of images at the photodetector surface.
13. The apparatus of claim 6 further including means to select the number of discrete LED sources employed in a given measurement whereby selection may be made to a minimum number, consistent with specific requirements for accuracy and spatial distribution of data on the measured surface thereby reducing the elapsed time required for data analysis.
14. The apparatus of claim 4 further including a video monitor connected to said photodetector for display of images on the photodetector surface, said video monitor including means for image-display expansion whereby an enlarged image of the illuminated exterior of measured surface can be presented in monochrome or color on the video monitor.
15. The apparatus of claim 1 further including optical means to provide a measurable reference when setting the axial focus position of the surface being measured with respect to said lens means.
16. The apparatus of claim 15 wherein said optical means is a telemicroscope delivering an image of the surface being measured to the operator's eye.
17. The apparatus of claim 15 wherein said optical means is a video camera producing an image of the surface being measured on a monitor where it can be observed by the operator.
18. The apparatus of claim 16 wherein said telemicroscope includes a first mirror means to access an image of the surface being measured and a second mirror means to access an image of the light beams reflected from the surface being measured.
19. The apparatus of claim 2 wherein said calibration means further includes fiducial target means on the calibration surface being reflected as a fiducial target image onto the photodetector whereby comparison of the size of the reflected fiducial target image with the actual fiducial target images enable the magnification of said lens means to be determined.
20. The apparatus of claim 19 wherein said fiducial calibration means comprises a primarily spherical calibration means having a flat surface with at least two separated marks thereon.
21. The apparatus of claim 20 wherein at least two separated marks are disposed on at least two mutually perpendicular intersecting diameters.
22. The apparatus of claim 19 wherein said fiducial calibration means comprises a circular ring marked onto a flat calibration surface, said ring being concentric with the optical axis.
23. The apparatus of claim 1 wherein said contoured surface is the anterior surface of a cornea.
24. The apparatus of claim 23 including laser-sculpturing apparatus having an axis of sculpturing laser-beam delivery wherein an optical element places the axis of laser beam delivery in coincidence with the axis of the contour-measuring apparatus, and synchronizing means interconnecting said laser-sculpturing apparatus and said contour-measuring apparatus for combined individual laser-sculpting and cornea-evaluation operations.
25. The apparatus of claim 24 in which the optical element is a beam-splitter whereby analysis of the unknown corneal surface contour and laser-sculpting operation may be accomplished in near-real time.
26. The apparatus of claim 15 including laser-sculpturing apparatus having an axis of sculpturing laser-beam delivery wherein an optical element places the axis of laser-beam delivery in coincidence with the axis of the contour-measuring apparatus, and synchronizing means interconnecting said laser-sculpturing apparatus and said contour-measuring apparatus for combined individual laser-sculpting and cornea-evaluation operations.
27. The method of measuring a three-dimensional contour of a surface, comprising the steps of:
directing a plurality of individual light beams onto a surface being measured;
focusing the reflected beams of light from the measured surface onto a photodetector to form measurable optical images;
determining both the local radius of curvature of the measured surface at each desired point of incidence of the individual light beams and the three-dimensional surface contours of the surface;
prior to the step of directing a plurality of individual light beams, reducing the instrument errors of the apparatus using the following steps:

substituting the surface to be measured with a calibration surface having a known contour;
sequentially determining and storing in memory the location on the calibration surface of each image of individual light points from the plurality of individual light beams directed onto the calibration surface; and determining the contour of the surface being measured from a differential evaluation of the reflection of each light point image from the surface being measured in comparison to the reflection of each light point image from the calibrated surface.
28. The method of claim 27 wherein said step of focusing the reflected beams of light includes the steps of:
disposing a lens transverse to an optical axis extending from said surface being measured to said photodetector; and directing the beams of light through a lens.
29. The method of claim 28 further including directing the focus beams of light through a telecentric aperture stop positioned on said optical axis between the lens and photodetector at the focal point of the lens.
30. The method of claim 29 including the step of independently adjusting the position of the calibration surface in each of three orthogonally related axes of displacement.
31. The method of claim 30 including setting the axial focus position of the surface being measured with respect to the lens.
32. The method of claim 31 including the steps of:
providing a laser-sculpturing apparatus having an axis of sculpturing laser-beam delivery;
placing said axis of laser-beam delivery in coincidence with the optical axis of the contour-measuring apparatus; and interconnecting the laser-sculpturing apparatus and the contour-measuring apparatus for combined individual laser-sculpturing and cornea-evaluation operations.
33. The method of claim 27 further comprising the step of measuring the contour of surface from the group consisting of corneas, optical lenses, mirrors, ball bearings and precision machine parts.
34. A contour measuring apparatus to measure the three-dimensional contour of a surface, comprising:
a contour measuring structure having a multi-point light source to direct a plurality of individual light beams each corresponding to individual light points of the multi-point light source onto the surface being measured;
a photodetector receiving reflections of the individual light beams from said surface for generating electrical output signals corresponding to electro-optically measurable optical images, each of said images corresponding to one of said light points;
means disposed between said surface being measured and said photodetector for focusing the reflected beams of light from the surface being measured onto the photodetector to form the measurable optical images;
means between the focusing means and said photodetector for limiting the cone angle of the rays of the individual light beams reflected from the surface whereby each of said reflected rays closely approximates a telecentric principal ray corresponding to a light point;
said focusing means comprising a lens having an optical axis extending through said contour measuring structure;
said photodetector including a photodetector surface into which said reflected light beams are focused, said photodetector surface being disposed transverse to said optical axis;
means receiving said electrical output signals from said photodetector for measuring the position of each optical image in the photodetector and for determining both the local radius of curvature of the measured surface at each point of incidence of the individual corresponding light beams and the average radius of curvature of the measured surface;
calibration means for reducing instrument errors of the apparatus, said calibration means including:
a calibration surface with a known contour to be positioned in substitution of said surface being measured;
means for determining the magnification of said lens; and fiducial target means on the calibration surface being reflected as a fiducial target image onto the photodetector whereby comparison of the size of the reflected fiducial target image with the actual fiducial target image enables the magnification of said lens to be determined.
35. The apparatus of claim 34 in which said means for limiting the cone angle comprises a telecentric aperture stop positioned between said lens and said photodetector substantially at the focal point of said lens.
36. The apparatus of claim 35 in which the telecentric aperture stop limits the cone angle of the light beams reflected from the surface being measured to produce uniformly sharp images of the reflected beams on the photodetector surface.
37. The apparatus of claim 36 further including a video monitor connected to said photodetector for display of the images of the reflected beams on the photodetector surface, said video monitor including means for image-display expansion whereby an enlarged image of the illuminated exterior of the measured surface can be presented in monochrome or color on the video monitor.
38. The apparatus of claim 35 further including means to determine and store in memory the location of each individual light point on said multi-point light source.
39. The apparatus of claim 38 wherein said means to determine and store include a frame grabber.
40. The apparatus of claim 39 wherein said means to determine both the local radius of curvature and the average radius of curvature includes computer means.
41. The apparatus of claim 40 wherein said individual light points comprise an array of individual LEDs.
42. The apparatus of claim 41 further including selectively operable means associated with said computer means to select a particular group of LED images for analysis and evaluation to the exclusion of other groups of images at the photodetector surface.
43. The apparatus of claim 41 further including means to select the number of discrete LED sources employed in a given measurement whereby selection may be made to a minimum number, consistent with specific requirements for accuracy and spatial distribution of data on the measured surface thereby reducing the elapsed time required for data analysis.
44. The apparatus of claim 43 wherein said calibration surface is substantially spherical.
45. The apparatus of claim 44 wherein the spherical calibration surface is polished.
46. The apparatus of claim 44 wherein said calibration means includes means for independently adjusting the position of the calibration surface in each of three orthogonally related axes of displacement to facilitate mutual alignment of the calibration surface with the optical axis through the apparatus and to set the axial focus position of the calibration surface with respect to the focusing means.
47. The apparatus of claim 46 further including means to support a spherical surface.
48. The apparatus of claim 47 wherein said calibration means includes means for independently adjusting the position of the calibration surface in each of three orthogonally related axes of displacement to facilitate mutual alignment of the calibration surface with the optical axis through the apparatus and to set the axial focus position of the calibration surface with respect to the focusing means.
49. The apparatus of claim 34 further including optical means to provide a measurable reference when setting the axial focus position of the surface being measured with respect to the focusing means.
50. The apparatus of claim 49 wherein said optical means includes a video camera producing an image of the surface being measured on a monitor where it can be observed by the operator.
51. The apparatus of claim 50 wherein said optical means further includes mirror means to access an image of the surface being measured.
52. The apparatus of claim 49 wherein said optical means is a telemicroscope delivering an image of the surface being measured to the operator's eye.
53. The apparatus of claim 52 wherein said optical means further includes mirror means to access an image of the surface being measured.
54. The apparatus of claim 49 including:
laser-sculpturing apparatus having an axis of sculpturing laser-beam delivery;
an optical element disposed so as to place the axis of laser beam delivery in coincidence with the optical axis of the contour-measuring structure whereby said laser-sculpturing apparatus and said contour-measuring structure are interconnected for combined individual laser-sculpting and cornea-evaluation operation.
55. The contour measuring apparatus of claim 54 wherein said means for determining includes means for computing and storing in memory the location of each individual light point.
56. The contour measuring apparatus of claim 55 including means for determining the average radius of curvature of the measured surface, the extreme long and short radii of said measured surface, the dioptric equivalent of each of said radii, the difference in the average optical powers on the directions of the principal astigmatic meridians, and the azimuthal orientations of said meridians.
57. A contour measuring apparatus to measure the three-dimensional contour of a surface, comprising:
a contour measuring structure having a multi-point light source to direct a plurality of individual light beams each corresponding to individual light points of the multi-point light source onto the surface being measured;
a photodetector receiving reflections of the individual light beams from said surface for generating electrical output signals corresponding to electro-optically measurable optical images, each of said images corresponding to one of said light points;
means disposed between said surface being measured and said photodetector for focusing the reflected beams of light from the surface being measured onto the photodetector to form the measurable optical images; said focusing means comprising a lens centered on an optical axis extending through said contour measuring structure;

means between the focusing means and said photodetector for limiting the cone angle of the rays of the individual light beams reflected from the surface whereby each of said reflected rays closely approximates a telecentric principal ray corresponding to a light point;
said photodetector including a photodetector surface into which said reflected light beams are focused, said photodetector surface being disposed transverse to said optical axis;
means receiving said electrical output signals from said photodetector for measuring the position of each optical image in the photodetector and for determining both the local radius of curvature of the measured surface at each point of incidence of the individual corresponding light beams and the average radius of curvature of the measured surface; and calibration means for reducing instrument errors of the apparatus, said calibration means including:
a calibration surface with a known contour to be positioned in substitution of said surface being measured;
and means for determining the magnification of said lens whereby the curvature of the measured surface can be determined.
58. The apparatus of claim 34 wherein said fiducial target means comprises a primary spherical calibration means having a flat surface with at least two separated marks thereon.
59. The apparatus of claim 58 wherein said at least two separated marks are disposed on at least two mutually perpendicular intersecting diameters.
60. The apparatus of claim 34 wherein said fiducial target means comprises a circular ring marked onto a flat calibration surface, said ring being concentric with optical axis.
61. The contour measuring apparatus to measure the three-dimensional contour of a surface, comprising:
a contour measuring structure having a multi-point light source to direct a plurality of individual light beams each corresponding to individual light points of the multi-point light source onto the surface being measured, said surface being the anterior surface of a cornea;
a photodetector receiving reflections of the individual light beams from said surface for generating electrical output signals corresponding to electro-optically measurable optical images, each of said images corresponding to one of said light points;

means disposed between said surface being measured and said photodetector for focusing the reflected beams of light from the surface being measured onto the photodetector to form the measurable optical images, said focusing means comprising a lens centered on an optical axis extending through said contour measuring structure;
means between the focusing means and said photodetector for limiting the cone angle of the rays of the individual light beams reflected from the surface whereby each of said reflected rays closely approximates a telecentric principal ray corresponding to a light point;
means receiving said electrical output signals from said photodetector for measuring the position of each optical image in the photodetector and for determining both the local radius of curvature of the measured surface at each point of incidence of the individual corresponding light beams and the average radius of curvature of the measured surface;
a laser-sculpturing apparatus having an axis of sculpturing laser-beam delivery;
a beam splitter disposed so as to place the axis of laser-beam delivery in coincidence with the optical axis through said contour measuring structure so that said laser-sculpturing apparatus and said contour-measuring structure are interconnected for combined individual laser-sculpting and cornea-evaluation operations.
62. The method of measuring a surface, comprising the steps of:
directing a plurality of individual light beams each corresponding to individual light points of a multi-point light source onto the surface being measured;
providing a photodetector for generating electrical output signals corresponding to electro-optically measurable optical images;
focusing the reflected beams of light from the measured surface onto the photodetector to form measurable optical images, each of said images corresponding to one of each light points, said step of focusing the reflected beams of light including the steps of:
disposing a lens transverse to an optical axis extending from said surface being measured to said photodetector;
directing the beams of light through said lens;
limiting the cone angle of the reflected beams of light whereby each individual beam closely approximates a telecentric principal ray of individual beam;
measuring the position of each optical image on the photodetector from the electrical output signals of the photodetector for determining both the local radius of curvature of the measured surface at each point of incidence of the individual light beams and average radius of curvature of the measured surface; and prior to the step of determining the radius of curvature of the measured surface, reducing the instrument errors of the apparatus using the following steps:
substituting the surface to be measured with a calibration surface having a known contour; and determining the magnification of the lens whereby the curvature of the measured surface can be determined.
63. The method of claim 62 further wherein the step of limiting the cone angle of the reflected beams further includes the step of directing the focused reflected beams of light through a telecentric aperture stop positioned on said optical axis between the lens and the photodetector at the focal point of the lens.
64. The method of claim 62 further comprising the step of measuring the contour of a surface selected from the group comprising corneas, optical lenses, mirrors, ball bearings and precision machine parts.
65. The method of claim 62 further including the step of determining and storing in memory the location of each individual light point.
66. The method of claim 62 wherein the step of determining the local radius of curvature includes the step of:
computing the local radius of curvature of the measured surface at each point of coincidence of the individual light beams, as a function of the height from the optical axis through the apparatus to the point at which a beam intercepts the measured surface Y1 and the distance from the origin "O" of the individual light points to the measured surface X1, the radius of curvature at the interception point of the beam with measured surface R1 substantially according to the formula R1 =
67. The method of claim 66 including the steps of computing the average radius of curvature of the measured surface, the extreme long and short radii of said measured surface, the dioptric equivalent of each of said radii, the difference in the average optical powers of the directions of the principal astigmatic meridians, and the azimuthal orientations of said meridians.
68. The method of measuring the three-dimensional contour of the surface of a cornea, comprising the steps of:
providing a multi-point light source;
directing a plurality of individual light beams each corresponding to individual light points of a multi-point light source onto the corneal surface being measured, said surface being the anterior surface of a cornea;
providing a photodetector for generating electrical output signals corresponding to electro-optically measurable optical images;
focusing the reflected beams of light from the corneal surface being measured onto the photodetector along an optical axis extending from the measured surface to the photodetector to form the measurable optical images, each of said images corresponding to one of said light points;
limiting the cone angle of the rays of the individual light beams reflected from the surface whereby each of said reflected rays closely approximates a telecentric principal ray corresponding to a light point measuring the position of each optical image on the photodetector from the electrical output signals of said photodetector for determining both the local radius of curvature of the measured corneal surface at each point of incidence of the individual corresponding light beams and the average radius of curvature of the measured surface;
providing a laser-sculpturing apparatus having an axis of sculpturing laser-beam delivery for laser sculpturing of corneas;
disposing a beam splitter so as to place the axis of laser-beam delivery in coincidence with the optical axis from the measured surface to the photodetector for combined individual laser-sculpting and cornea-evaluation operations.
69. A contour measuring apparatus to measure the three-dimensional contour of a surface, comprising:
a multi-point light source to direct a plurality of individual light beams each corresponding to individual light points of the multi-point light source onto the surface being measured;
a photodetector receiving reflections of the individual light beams from the measured surface for generating electrical output signals corresponding to electro-optically measurable optical images, each of said images corresponding to one of said light points;
means disposed between said surface being measured and said photodetector for focusing the reflected beams of light from the surface being measured onto the photodetector to form the measurable optical images;
means between the focusing means and said photodetector for controlling the size of the area on the measured surface from which the beams of light are reflected;
means receiving said electrical output signals from said photodetector for measuring the position of each optical image in the photodetector and for determining both the local radius of curvature of the measured surface at each point of incidence of the individual corresponding light beams and the average radius of curvature of the measured surface.
70. The contour measuring apparatus of claim 69 wherein said means for controlling the size of the area further comprises means for limiting the cone angle of the rays of the individual light beams reflected from the measured surface whereby each of said reflected rays closely approximates a telecentric principal ray corresponding to a light point.
71. The contour measuring apparatus of claim 70 wherein said means for controlling the size of the area comprises a telecentric aperture stop having an effective aperture of no larger than f/13.
72. The apparatus of claim 71 in which said telecentric aperture stop is positioned between said lens and said photodetector substantially at the focal point of said lens.
73. The apparatus of claim 72 wherein the focusing means comprises a lens having an optical axis extending therethrough; and said photodetector includes a photodetector surface into which said reflected light beams are focused, said photodetector surface being disposed transverse to said optical axis.
74. The apparatus of claim 73 further including means to determine and store in memory the location of each individual light point on said multi-point light source.
75. The apparatus of claim 74 wherein said means to determine and store include a frame grabber.
76. The apparatus of claim 75 wherein said means to determine both the local radius of curvature and the average radius of curvature comprises a computer.
77. The method of measuring the three-dimensional contour of the surface, comprising the steps of:
directing a plurality of individual light beams each corresponding to individual light points of a multi-point light source onto the surface being measured;
reflecting the individual light beams from the measured surface onto a photodetector for generating electrical output signals corresponding to electro-optically measurable optical images, each of said images corresponding to one of said light points;
focusing the reflected beams of light from the surface being measured onto the photodetector to form the measurable optical images;
controlling the size of the area on the measured surface from which the beams of light are reflected;
measuring the position of each optical image in the photodetector; and determining both the local radius of curvature of the measured surface at each point of incidence of the individual corresponding light beams and the average radius of curvature of the measured surface.
78. The method of claim 77 wherein the step of controlling the size of the area further includes the step of limiting the cone angle of the rays of the individual light beams reflected from the measured surface whereby each of said reflected rays closely approximates a telecentric principal ray corresponding to a light point.
79. The method of claim 78 wherein the step of controlling the size further includes the step of directing the reflected rays of the individual light beams through a telecentric aperture stop having an effective aperture of no larger than f/13.
80. The method of measuring the local radii of curvature (R1)1 and optical powers (P1)1 at i points with coordinates (X1,Y1)1 of a three-dimensional contour on a surface being measured, including the steps of:
locating the center of curvature of the surface substantially on the optical axis of a contour measuring apparatus;
directing a plurality of individual light beams, each corresponding to individual light points of a multi-point light source on a concave, substantially spherical surface onto the convex surface being measured;
receiving reflections of the individual light beams from said surface on a photodetector;
generating electrical output signals corresponding to positional relationships of optical images of said light points;
determining the radial distances (Y1)1 from said optical axis to each of the i images of the array of i light points located at points with known coordinates (X2, Y2)1 on the concave, substantially spherical surface of radius R2 centered on said optical axis and located at a known distance d1 measured along the optical axis in front of the convex surface;
measuring the (X1)1 coordinates of these same i images from the equation:
(X1) 1 = where:

A = (Y1)1 - (Y2)1 B = (X2)1 - (X1)l1 D = A [2(Y1)1 - A]
E = 2A[AXC - XC(Y2)1 - (X2)1(Y1)1]
G = A2[(Y1)12 - XC2] + 2AXCX2Y1 XC = d1 + (R1) 1 (R1)1' = assumed approximate value for this parameter; and measuring by successive approximations, the local radius (R1)1 from the equation:

(R1) 1 =
81. The method of claim 80 including the step of measuring by successive approximations, the local optical power (P1)1 (in diopters) from the equation:
(P1)1 = 1000 (N-1)/(R1)1 where: N = index of refraction of the material on which the surface under evaluation is located.
82. The method of claim 80 further including the step of limiting the cone angle of the rays within the individual light beams reflected from the convex surface to be measured whereby these rays closely approximate a telecentric principal ray corresponding to an individual light point and limit the area intercepted on said surface to a small localized area.
83. The method of claim 81 further including the step of focusing the reflected light beams from said surface onto the photodetector to form measurable optical images.
84. The method of claim 83 further including the step of measuring the position of each optical image formed on the photodetector.
85. The method of measuring the coordinates (X2)1, (Y1)1 of each light point of the contour measuring apparatus used in the method of claim 80, including the steps of:
substituting a generally spherical calibration surface of known radius of curvature R2 in lieu of the surface being measured;
measuring the radial distance (Y1)1 from the optical axis to each of the i images of said array of i point light points using the following equations:

K1 = (XC - X1)Y12 K2 = (X1 - XC) Y1 K3 = Y12 - XC2 + 2XCX1 - X12 K4 = 2(XC2Y1 - XcX1Y1 - Y13 K5 = Y14 + X12Y12 - XCC2Y12 H = 4K22 + K32 I = (4K2K3R2 + 2K3K4 + 8 K1K2) / H
J = (4K12 + 4K1K3R2 + 4K2K4R2 + 2K3K5 + K42) / H
L = (4K1K4R2 + 4K2K5R2 + 2K4K5) / H

M = (4K1K5R2 + K52) / H
Y24 + IY23 + JY22 + LY2 + M = 0 X2 =
86. An apparatus to measure the three-dimensional contour of a surface, comprising:
a contour measuring device having an optical axis extending therethrough, said contour measuring device comprising:
means to direct light beams onto the surface being measured;
means for receiving reflections of said light beams from the surface being measured; and means connected to the reflection receiving means for measuring the contour of said surface;
means for positioning the surface being measured with respect to the reflection receiving means to establish a desired axial distance therebetween; and said means for positioning comprising an optical microscope attached to said contour measuring device.
87. The apparatus of claim 86 wherein said optical microscope is attached to said contour measuring device so that a line of sight extending through said optical microscope is parallel to the axis through said contour measuring device.
CA000581517A 1987-11-25 1988-10-27 Topography measuring apparatus Expired - Lifetime CA1308948C (en)

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Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4993826A (en) * 1987-11-25 1991-02-19 Taunton Technologies, Inc. Topography measuring apparatus
US4998819A (en) * 1987-11-25 1991-03-12 Taunton Technologies, Inc. Topography measuring apparatus
JPH01195839A (en) * 1988-02-01 1989-08-07 Topcon Corp Ophthalmologic instrument
US5062702A (en) * 1990-03-16 1991-11-05 Intelligent Surgical Lasers, Inc. Device for mapping corneal topography
DE4030002A1 (en) * 1990-09-21 1992-03-26 Rth Electronic Gmbh Cornea unevenness measurement and display - by computer graphics using digital reflected image data input
US5289267A (en) * 1991-10-04 1994-02-22 Kms Fusion, Inc. Electro-optical system for gauging surface profile deviations
GB9205655D0 (en) * 1992-03-14 1992-04-29 Roke Manor Research Improvements in or relating to surface curvature measurement
EP0561178B1 (en) * 1992-03-14 1997-10-29 Roke Manor Research Limited Improvements in or relating to surface curvature measurement
JP3298185B2 (en) * 1992-11-05 2002-07-02 株式会社ニコン Ophthalmic equipment
US5477332A (en) * 1992-12-17 1995-12-19 Mcdonnell Douglas Corporation Digital image system and method for determining surface reflective and refractive characteristics of objects
US5526072A (en) * 1993-04-14 1996-06-11 Alcon Laboratories, Inc. Apparatus and technique for automatic centering and focusing a corneal topographer
DE69535172T2 (en) * 1994-02-28 2007-07-05 Menicon Co., Ltd., Nagoya OPHTHALMOLOGICAL MEASUREMENT AND INSPECTION DEVICE
GB2289943B (en) * 1994-05-28 1998-05-13 Roke Manor Research Improvements in or relating to apparatus for the measurement of curvature of a surface
EP0714193A3 (en) * 1994-11-24 2000-11-22 Marconi Communications Limited Improved telecommunication system through mains electricity conductors
US5517261A (en) * 1994-12-13 1996-05-14 Alcon Laboratories, Inc. Focusing method for a corneal topographer
JP3448795B2 (en) * 1996-04-11 2003-09-22 株式会社ニコン Ophthalmic equipment
US5891132A (en) * 1996-05-30 1999-04-06 Chiron Technolas Gmbh Opthalmologische Systeme Distributed excimer laser surgery system
ES2215229T3 (en) * 1996-05-30 2004-10-01 Technolas Gmbh Ophthalmologische Systeme LASER SYSTEM EXCIMERO FOR EYE SURGERY.
US5941874A (en) * 1997-03-10 1999-08-24 Chiron Technolas Gmbh Opthalmologische Systeme Simulating a laser treatment on the eye by pretreating a contact lens
US6302876B1 (en) 1997-05-27 2001-10-16 Visx Corporation Systems and methods for imaging corneal profiles
US6194697B1 (en) * 1999-04-13 2001-02-27 Hewlett-Packard Company Calibration system for an imaging apparatus and method
US20020159621A1 (en) * 2001-04-26 2002-10-31 Memphis Eye & Cataract Associates Ambulatory Surgery Center (Dba Meca Laser And Surgery Center) System for automatically detecting eye corneal striae using projected and reflected shapes
US7513621B2 (en) * 2003-10-24 2009-04-07 Nevyas Herbert J Ophthalmic operative keratometer with movable fixation/centration device
CA2612237C (en) * 2005-06-30 2013-05-21 Wavefront Sciences, Inc. Method and system for measuring the curvature of an optical surface
US7859677B2 (en) * 2006-12-13 2010-12-28 Bausch & Lomb Incorporated Optical calibration system and method
AU2008251316B2 (en) 2007-05-11 2014-05-29 Amo Development, Llc Combined wavefront and topography systems and methods
US7976163B2 (en) 2007-06-27 2011-07-12 Amo Wavefront Sciences Llc System and method for measuring corneal topography
US7988290B2 (en) * 2007-06-27 2011-08-02 AMO Wavefront Sciences LLC. Systems and methods for measuring the shape and location of an object
US7988293B2 (en) * 2008-11-14 2011-08-02 AMO Wavefront Sciences LLC. Method of qualifying light spots for optical measurements and measurement instrument employing method of qualifying light spots
US8817090B2 (en) * 2009-04-02 2014-08-26 GM Global Technology Operations LLC Luminance uniformity compensation of vector projection display
CN101788274B (en) * 2010-03-15 2012-08-08 电子科技大学 Method for 3D shape measurement of colourful composite grating
US8780362B2 (en) 2011-05-19 2014-07-15 Covidien Lp Methods utilizing triangulation in metrology systems for in-situ surgical applications
US8622546B2 (en) 2011-06-08 2014-01-07 Amo Wavefront Sciences, Llc Method of locating valid light spots for optical measurement and optical measurement instrument employing method of locating valid light spots
US9113822B2 (en) 2011-10-27 2015-08-25 Covidien Lp Collimated beam metrology systems for in-situ surgical applications
DE102012019474A1 (en) * 2012-09-28 2014-04-03 Carl Zeiss Meditec Ag Device for the reliable determination of biometric measurements of the entire eye
JP6067407B2 (en) * 2013-02-20 2017-01-25 第一実業ビスウィル株式会社 Inspection device
US9351643B2 (en) 2013-03-12 2016-05-31 Covidien Lp Systems and methods for optical measurement for in-situ surgical applications
NL2018712B1 (en) 2017-04-13 2018-10-24 Cassini B V Eye measuring apparatus
CN107883895B (en) * 2017-11-21 2024-02-13 苏州睿牛机器人技术有限公司 Multi-light source laser detection sensor and detection method thereof
GB201805561D0 (en) * 2018-04-04 2018-05-16 Univ Aston Ophthalmic device

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3937566A (en) * 1972-03-06 1976-02-10 Wesley-Jessen Inc. Process for producing contact lenses
US4019813A (en) * 1976-01-19 1977-04-26 Baylor College Of Medicine Optical apparatus for obtaining measurements of portions of the eye
DE2641004C2 (en) * 1976-09-11 1981-12-17 Battelle-Institut E.V., 6000 Frankfurt Device for measuring the corneal curvature
JPS5843090B2 (en) * 1977-04-12 1983-09-24 キヤノン株式会社 Ophthalmological device with adjustment system
US4253743A (en) * 1977-05-17 1981-03-03 Canon Kabushiki Kaisha Eye testing instrument
JPS53144193A (en) * 1977-05-20 1978-12-15 Canon Kk Ophthalmologic machine having operating distance detector
US4157859A (en) * 1977-05-26 1979-06-12 Clifford Terry Surgical microscope system
US4265518A (en) * 1977-06-30 1981-05-05 Canon Kabushiki Kaisha Variable magnification apparatus having illumination compensating ability
US4180325A (en) * 1977-07-05 1979-12-25 Humphrey Instruments, Inc. Lens meter with automated readout
US4182572A (en) * 1977-07-05 1980-01-08 Humphrey Instruments Inc. Lensmeter utilizing non-parallel light
US4213678A (en) * 1977-09-29 1980-07-22 Retina Foundation Scanning ophthalmoscope for examining the fundus of the eye
DE2805084C3 (en) * 1978-02-07 1980-10-16 Optische Werke G. Rodenstock, 8000 Muenchen Photopometer
US4272190A (en) * 1978-08-14 1981-06-09 Typalogics Optical measuring system
JPS5542624A (en) * 1978-09-20 1980-03-26 Canon Kk Automatic eye refraction measuring system
US4259589A (en) * 1979-07-20 1981-03-31 Solid Photography, Inc. Generation of contiguous data files of three-dimensional information
US4256384A (en) * 1979-10-15 1981-03-17 Konan Camera Research Institute Eyeball examining device
US4407572A (en) * 1980-06-12 1983-10-04 Humphrey Instruments, Inc. Keratometer
US4355871A (en) * 1980-07-14 1982-10-26 Diversitronics, Inc. Keratometer
NL8005259A (en) * 1980-09-22 1982-04-16 Philips Nv DEVICE FOR MEASURING THE SURFACE OF AN OBJECT.
US4429960A (en) * 1980-10-31 1984-02-07 Mocilac Joseph P Keratometric device
US4469416A (en) * 1981-04-24 1984-09-04 Tokyo Kogaku Kikai Kabushiki Kaisha Automatic focusing means for an ophthalmoscopic instrument
US4572628A (en) * 1981-05-29 1986-02-25 Nippon Kogaku K.K. Method of and apparatus for measuring radius
US4439025A (en) * 1981-08-13 1984-03-27 Smirmaul Heinz J Variable circular dual image corneal radius measurement instrument
US4660946A (en) * 1981-09-21 1987-04-28 Canon Kabushiki Kaisha Cornea shape measuring method and apparatus
JPS5875531A (en) * 1981-10-28 1983-05-07 株式会社トプコン Apparatus for measuring curvature
US4440477A (en) * 1981-10-30 1984-04-03 Schachar Ronald A Method and device for measuring the optical power of the cornea
DE3150124C2 (en) * 1981-12-18 1985-01-31 Fa. Carl Zeiss, 7920 Heidenheim Device for examining the anterior segments of the eye
US4490022A (en) * 1982-01-04 1984-12-25 Reynolds Alvin E Apparatus for corneal corrective techniques
JPS5938A (en) * 1982-06-23 1984-01-05 有限会社 宇津木光学研究所 Intraocular observing and inspecting apparatus
US4494838A (en) * 1982-07-14 1985-01-22 The United States Of America As Represented By The Secretary Of The Air Force Retinal information mapping system
US4666269A (en) * 1982-08-09 1987-05-19 Canon Kabushiki Kaisha Ophthalmologic apparatus
US4569576A (en) * 1982-08-31 1986-02-11 Moskovsky Nauchno-Issledovatelsky Institut Glaznykh Boleznei Imeni Gelmgoltsa Method and device for determining cornea surface topography
US4710003A (en) * 1982-10-21 1987-12-01 Canon Kabushiki Kaisha Cornea shape measuring apparatus
US4540254A (en) * 1982-10-26 1985-09-10 Humphrey Instruments, Inc. Keratometer having peripheral light entrance and exit paths
DE3245939C2 (en) * 1982-12-11 1985-12-19 Fa. Carl Zeiss, 7920 Heidenheim Device for generating an image of the fundus
JPS59151935A (en) * 1983-02-18 1984-08-30 株式会社トプコン Eye bottom camera
JPS59156324A (en) * 1983-02-25 1984-09-05 株式会社トプコン Signal detector of ophthalmic machine
JPS59174144A (en) * 1983-03-22 1984-10-02 キヤノン株式会社 Ophthalmic photographing apparatus
JPS59183727A (en) * 1983-04-02 1984-10-18 株式会社トプコン Focus alignment detector of ophthalmic machine
EP0151627A1 (en) * 1983-08-11 1985-08-21 AMOILS, Selig Percy Method and apparatus for use in ocular surgery
US4692003A (en) * 1983-11-07 1987-09-08 Adachi Iwao P Real-time analysis keratometer
US4718418A (en) * 1983-11-17 1988-01-12 Lri L.P. Apparatus for ophthalmological surgery
US4665913A (en) * 1983-11-17 1987-05-19 Lri L.P. Method for ophthalmological surgery
US4685140A (en) * 1984-06-26 1987-08-04 Kera Corporation Keratograph autoscanner system
US4582404A (en) * 1984-07-16 1986-04-15 Hamilton C B Sagometer
JPS6185917A (en) * 1984-10-02 1986-05-01 株式会社トプコン Self-awakening eye examination apparatus
US4662730A (en) * 1984-10-18 1987-05-05 Kerascan, Inc. Scanning keratometers
US4761071A (en) * 1984-11-06 1988-08-02 Baron William S Apparatus and method for determining corneal and scleral topography
US4669466A (en) * 1985-01-16 1987-06-02 Lri L.P. Method and apparatus for analysis and correction of abnormal refractive errors of the eye
US4641349A (en) * 1985-02-20 1987-02-03 Leonard Flom Iris recognition system
US4747683A (en) * 1986-01-17 1988-05-31 Eye Research Institute Of Retina Foundation Method and device for in vivo wetting determinations
US4743107A (en) * 1986-02-25 1988-05-10 Kowa Company Ltd. Ophthalmological diagnosis method and apparatus

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