CA1310870C - Apparatus for hypodermic injection of liquids - Google Patents

Apparatus for hypodermic injection of liquids

Info

Publication number
CA1310870C
CA1310870C CA000583215A CA583215A CA1310870C CA 1310870 C CA1310870 C CA 1310870C CA 000583215 A CA000583215 A CA 000583215A CA 583215 A CA583215 A CA 583215A CA 1310870 C CA1310870 C CA 1310870C
Authority
CA
Canada
Prior art keywords
capsule
piston
actuator piston
liquid
reservoir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000583215A
Other languages
French (fr)
Inventor
Jack Newman
James A. Monroe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sy Quest International Ltd
Original Assignee
MEDHI-TEK INTERNATIONAL Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MEDHI-TEK INTERNATIONAL Ltd filed Critical MEDHI-TEK INTERNATIONAL Ltd
Application granted granted Critical
Publication of CA1310870C publication Critical patent/CA1310870C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/30Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053Media being expelled from injector by pressurised fluid or vacuum

Abstract

ABSTRACT
A device to introduce a liquid into the hypoderma, the device includes a reservoir which receives a gas under pressure the gas is delivered via a valve to an interacting piston and cylinder. When the gas is delivered to the piston the piston moves to eject a liquid from a capsule mounted within the device. The liquid contained in the capsule is then ejected through a nozzle located against the skin of the user.

Description

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This invention relates to gas operated apparatus to introduce liquid into the hypoderma. Such devices have use in the administration of for example local anaesthetlc and insulin and the like.
For many years it was the practlce to deposlt medicaments into the hypoderma by the use of a device including a tubular needle connected to a reservoir of medlcanlent lncorporatlng a piston. The needle was inserted through the epidermls into the hypoderma and the medicament was discharged by moving the piston along the reservoir. Such devices had several problems. Firstly the penetration of the needle was a possible cause for infection and there was the patient resistance to the dlscomfort associated with the insertion of the needle.
Gas operated devlces were devlsed as an alterndtlve to needle devlces. In the gas operated devlce llquld medlcament was discharged from a reservoir through a port as a spray by a plston moved along the reservoir by sub~ecting it to a force created by the sudden release of gas. Thls device has the obvlous advantage that there was no skin penetratlon and hence no dlscomfort and no possibillty of infection.
The common forms of gas devlce comprised a holder to whlch was coupled to a container of medicament in a manner alignlng lt wlth the plston to be gas operated and whlch provided means to hold a gas filled capsule ln the holder. By puncturlng the capsule the gas was released lnto : a cyllnder and the piston thereln was drlven lnto the contalner to dlscharge the medlcament through a port ~n the contalner.
; Such an arrangement has several dlsadvantages. For example theholder as provlded was a large member and was complex havlng to provlde securement means for the medlcament container and the gas capsule. It had to provlde a plston mountlng arrangement and means to releasably hold th~
gas capsule securely ln a gas tlght manner and puncture the gas capsule.
In short the devlce was large and complex and correspondlngly expenslve.
DG:0155W

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Disclosed in PCT ~pplication US 86/02718 (publi~hed June 18, 1987 under PCT publication no. W087/03494) i3 a device with~n which a co~ventional syringe is mounted. Prior to mounting, the n~edle i~ r~ov~d and the d~vice employs gas under pressure to cause the piston in the d~vice to mcve ts ~pray from the syringe body a stream of medication directed at tha ~kin of the patient. This palticular device has the disadvantage that it is gen,~rally oo~plex to use and therefore t~me consuming. Firstly, the s~ringe i~ provided wi~l a needle and a liquid mRdication drawn into the syringe. The needle is then remcved and the sy-ringe mounted within the device. The d~vice i~ then applie~ to the ~in and operator.
~t ls the object of the present ~nvent~on to oYercomQ or substantially ameliorate the above disadvantages.
There is disclosed herein a device to introduce a liquld ~nto a patient sald liquld being contained ln a capsule wh~ch lncludes a hollow body with a nozzle end through which the liquid exits from within the capsule and a capsule piston movably mounted ~ithln the body and operable to push the liquid out through said nozzle end~ sald dev~ce comprising:
a body providing a reservoir to receive a gas under pressure;
an interactlng actuator piston and cyllnder pro~iding a variable volume space w~th sa~ cyl~nder be~ng f~xed to said body;
duct means extending from said reservoir to sald space;
operator manipulable valve means closing said duct and operable by a user to open satd duct to permit gas to pass from said reservoir to sald space to cause movement of sald actuator plston withln said cylinder;
a capsule mounting to rece~ve a capsule; and a pistqn rod extend~ng from sald actuator piston and extending there~rom towards sald mountlng and engageable wlth the capsule piston to cause movement thereof upon gas under pressure being dellvered to said space.
The present ~nvention in lts preferred form has beQn dev~sed to DG:0155W

~ 3 ~

overcome the above problems by providlng a simple unitary apparatus which is provided complete with medicament and pressurlsed gas supply. A single use renders it unsuitable for further use and lt must be thrown away. rhe design and the materlal of manufacture of the device proposed by the present invention makes it economlcally practlcal to throw the devlce away after a slngle usage.
To cater for the varylng amounts of a medlcament a user may require the present device ln lts preferred form to be adjustable so that a predetermlned amount of ~he med~cament can be d~scharged. Thls will mean that for some users there will be an amount of medlcament thrown away at each treatment. As will be understood the cost of a medlcament such as insulln for a diabetlc person is qulte small compared to the convenience of having a dosage adjustable lnexpenslve devlce that ls convenient to carry and store is economical to purchase and allows the admlnlstratlon of the ~nsulin ~n a qu~ck s~mple and convenient manner. For the above reason lt is proposed to provide a reservolr for the medlcament whlch will cater ;~ for a range of dosages most likely to be needed and thereby allow the user to select the amount th~t ls requlred to be admlnlstered.
A presently preferred embodlmen~ of the lnvention wlll now be descrlbed wlth reference to the accompanying drawlng. It ls presently intended that the dev~ce w~ll be made substantially completely fro~ clear polycarbonate ln an in~ectlon mouldlng process.
As lllustrated the devlce comprises a body 1 wlth a gas reservoir 2 at one end having a valve 3 of known type whereby gas can be lntroduce~
lnto the reservolr 2 of a fln~shed product. At the fore end of the reservolr there ls a tubular neck 4 wlth a weak ~one lndlcated 5 where the neck jolns the reservolr. As wlll be understood lf the neck ls broken off .-r ~ the reservoir the gas there~n wlll escape. The selected ~ater~al of manufacture allows the nQck to be readlly broken oPf.
DG:0155~

- ~3~ ~7~

The neck 4 extends lnto a tubular bore 6 in the body l whlch lncludes an annular shoulder 7. The shoulder 7 serves as a piston travel stop as will be descrlbed and a guide for a piston rod 8 hav~ng a plston head 9 sealingly slidably mounted ~n the bore 6. There is a gas escape vent 10 in the wall of the body 1 in communcation wlth the bore 6. The fore end of the bore 6 ls threaded at 11.
A llquld medicament capsule 12 is provided as a fitment for the devtce. The capsule is externally threaded at 13 enabling ~t to be screwed lnto the bore threads 11. The capsu~e has a port 14 at its fore end and the port 14 ls sealed by a seal that wlll yleld when pressure is applied to llquid medicament housed in the bore 15 of the capsule 12. Pressure ls applied to the medlcament by a plston 16 slldably housed in the bore 15.
The exter~or of the capsule 12 is marked ln any sultab~e manner to indicate fractions of the capacity of the bore 15. For example there may be external marklngs on the capsule to dlv~de the bore length into flve sectlons each of Y mls. By threading the capsule 12 into the body the marklngs on the capsule wlll pass by a datum mark on the body for example the end face 17 of the body 1 could be such a mark. Detent means ls preferably provlded whereby the detent ls releasably engaged each tlme a graduation on the capsule~l2 is allgned with the datum mark. In thls way the capsule can be releasably locked ln a des~red positlon.
By axially movlng the capsule 12 (as a result of rotatlng lt) the posltlon of the capsule 12 relative to the end 18 of the plston rod changes. When the eapsule is fully ln the maxlmum amount of medlcament ~ 25 will be dlspensed. By threadlng the capsule 12 out the amount of - medlcament dispensed can be reduced.
It wlll be noted that as lllustrated the plston 9 ~s ln lts zero posltlon agalnst the shoulder 19. The stroke of the plston 9 ls llmlted to the dlstance X and therefore when the capsule ls threaded fully lnto the ~G:0155W

~3~7~

body so the shoulder 20 engages the end of the body the piston 16 witl be adjacent the end 18 of the piston rod. The maximum stroke of ~he piston 16 is slightly greater than X. It follows that when the piston 9 moves the distance X the piston 16 will move the same distance and substantially the whole of the med~cament in the capsule 12 wlll be ejected. If the capsule is moved out of the body 1 the piston rod 18 will be spaced from the piston 16 and although the piston 9 will move X the piston 16 will move less than X.
In order to release the gas ~n the capsule 2 there ~s a nec~ breaker in the form of a plunger 21. Pressure ls applied to the plung~r 21 by a flexible arm 22 through a lu~ 23 thereon. The arm 22 has a ring end 24 rotatably mounted on the body part 2 between shoulders 25. There is a detent 26 on the ring 24 shown engaged in a depression 27 ~n the body part 2 to align the lug 23 with the plunger 21. In the inoperative position the 15 rtng 24 would be rotated until the detent 26 angages in the recess 28 ln the body part 2.
In an operatlonal sequence a capsule 12 would be fitted to the devlce and the amount of medlcament to be dlspensed would be chosen by the degree to which the capsule 12 ls threaded ~nto the body 1. The lug 23 would be placed over~the plunger 21. The devlce would be posltioned with the port 14 over the part o? the user where the ~l~nject~on~ ls to take place. The arm 22 would be depressed and the plunger 21 would be depressed and the neck 4 would be broken of~ the capsule 2. The gas would escape and drlve the piston 9 the dlstance X untll lt engages the shoulder 7 at th~s tlme the port 10 would be uncovered and the gas behlnd the plston 9 would escape to atmosphere. ~hllst the p~ston 9 ls advanc~ng the end 18 of the plston rod 8 woutd be dr~v~ng the piston 16 ~n the capsule bore 15 causlng . r ~ the med~cament there~n tu e~ect from the port 14. Depend1ng upon the , . ~
amount the capsule 12 ls thread~d ~nto the body 1 the p~ston 16 w~ll move 13~$70 the distance X or a fract~on of that dlstance and the amount of medicament ejected will vary accordingly.
Whilst a presently preferred embodiment of the invention has been described hereinbefore it is to be understood that variations can be made to the specific embodiment described without departlng from the inventive concept. By way of example only, the manner in which the piston 9 is regulated in its travel can be other than as disclosed. The manner in which the neck 4 is caused to be broken can be other than as described.
The arm 22 may not be connected to the rotatable band 24 and may be a fixture on the body and merely be flexible up and down.

^~

OG:0155hi

Claims (9)

1. A device for introducing a liquid into a patient, including:
a capsule for containing the liquid, the capsule including a hollow body with a nozzle end through which the liquid exits from within the capsule, and a capsule piston movably mounted within the body and operable to push the liquid out through said nozzle end;
a body providing a reservoir for receiving a quantity of gas under pressure from a gas source;
an interacting actuator piston and cylinder assembly, within the body, providing a variable volume space behind the actuator piston;
a neck, having a closed end, extending from said reservoir to said space behind the actuator piston;
means operable by a user to open said closed end to permit said quantity of gas to pass from said reservoir to said space behind the actuator piston to cause movement of said actuator piston within said cylinder;
a piston rod extending from said actuator piston towards an anterior end of the body and engageable with the said capsule piston to cause movement thereof upon said quantity of gas under pressure being delivered to said space behind the actuator piston;
a capsule mounting means, at the anterior end of the body, to connect the capsule to the body while allowing the capsule to be axially moveable along the anterior end so that the distance between the capsule piston and a front end of the piston rod can be varied so that the amount of penetration of the piston rod into the capsule, upon movement of the actuator piston, may be adjusted to vary the amount of liquid expelled from the capsule.
2. The device of claim 1 wherein said mounting means includes a threaded recess at the anterior end of the body, and external threads on the capsule that are received within said recess, so that rotation of the capsule axially moves the capsule along the anterior end of the body to adjust the position of he capsule.
3. The device of claim 2 wherein the mounting means further comprises detent means for engaging the capsule.
4. A device for introducing a liquid into a patient, including:
a capsule for containing the liquid, the capsule includes a hollow body with a nozzle end through which the liquid exits from the capsule, and a capsule piston movably mounted within the body and operable to push the liquid out through said nozzle end;
a body providing a reservoir for receiving a quantity of gas under pressure;
an interacting actuator piston and cylinder assembly, within the body, providing a variable volume space behind the actuator piston;
a frangible neck extending from said reservoir into said space behind the actuator piston;
means operable by a user to break said frangible neck to permit sad gas to pass from said reservoir to said space behind the actuator piston to cause movement of said actuator piston within said cylinder;
a piston rod extending from said actuator piston towards an anterior end of the body and engageable with the said capsule piston to cause movement thereof upon said quantity of gas under pressure being delivered to said space behind the actuator piston; and a capsule mounting means, at the anterior end of the body, to connect the capsule to the body while allowing the capsule to be axially moveable along the anterior end so that the distance between the capsule piston and a front end of the piston rod can be varied so that the amount of penetration of the piston rod into the capsule, upon movement of the actuator piston, may be adjusted to vary the amount of liquid expelled from the capsule.
5. The device of claim 4 wherein said neck includes a weak section, said neck being fracturable and wherein said device further includes trigger means operable by a user to fracture sand neck.
6. The device of claim 4 wherein said cylinder and mounting means are integrally formed, said mounting means is internally threaded at the anterior end of the body, and wherein external threads on the capsule are received within said recess so that notation of the capsule axially moves the capsule along the anterior end of the body to adjust the position of the capsule.
7. The device of claim 6 wherein said mounting means includes detent means for engaging the capsule.
8. The device of claim 4, wherein the means openable by a user to break said frangible neck further comprises a plunger which extends radially through the body adjacent the frangible neck.
9. The device of claim 8 further comprising a ring rotatably mounted on the body, the ring supporting an arm which is positionable over the plunder for facilitating activation of the plunger.
CA000583215A 1987-11-16 1988-11-16 Apparatus for hypodermic injection of liquids Expired - Lifetime CA1310870C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPI5441 1987-11-16
AUPI544187 1987-11-16

Publications (1)

Publication Number Publication Date
CA1310870C true CA1310870C (en) 1992-12-01

Family

ID=3772580

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000583215A Expired - Lifetime CA1310870C (en) 1987-11-16 1988-11-16 Apparatus for hypodermic injection of liquids

Country Status (3)

Country Link
US (1) US5009637A (en)
AU (1) AU628029B2 (en)
CA (1) CA1310870C (en)

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Also Published As

Publication number Publication date
AU2563988A (en) 1989-05-18
AU628029B2 (en) 1992-09-10
US5009637A (en) 1991-04-23

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