CA2032592A1 - Dual subcoated simulated capsule-like medicament - Google Patents

Dual subcoated simulated capsule-like medicament

Info

Publication number
CA2032592A1
CA2032592A1 CA2032592A CA2032592A CA2032592A1 CA 2032592 A1 CA2032592 A1 CA 2032592A1 CA 2032592 A CA2032592 A CA 2032592A CA 2032592 A CA2032592 A CA 2032592A CA 2032592 A1 CA2032592 A1 CA 2032592A1
Authority
CA
Canada
Prior art keywords
medicament
dual
subcoating
capsule
simulated capsule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2032592A
Other languages
French (fr)
Other versions
CA2032592C (en
Inventor
Marli F. Batista
Thomas J. Markley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson Consumer Inc
Original Assignee
McNeil PPC Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McNeil PPC Inc filed Critical McNeil PPC Inc
Publication of CA2032592A1 publication Critical patent/CA2032592A1/en
Application granted granted Critical
Publication of CA2032592C publication Critical patent/CA2032592C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

Abstract

A simulated capsule-like medicament comprising a dual subcoating comprising an initial subcoating of a water soluble film forming polymer, e.g. povidone and a secondary subcoating of a mixture of two soluble film forming polymers, e.g. povidone and hydroxypropyl methylcellulose and a hydrophobic plasticizer, e.g. castor oil, which provides for a smooth uniform and substantially bubble free outer coating, e.g. gelatin, for the capsule-like medicament; and a process of making such medicaments.
CA002032592A 1990-01-22 1990-12-18 Dual subcoated simulated capsule-like medicament Expired - Lifetime CA2032592C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/468,434 US5198227A (en) 1990-01-22 1990-01-22 Dual subcoated simulated capsule medicament
US468,434 1990-01-22

Publications (2)

Publication Number Publication Date
CA2032592A1 true CA2032592A1 (en) 1991-07-23
CA2032592C CA2032592C (en) 1996-02-13

Family

ID=23859800

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002032592A Expired - Lifetime CA2032592C (en) 1990-01-22 1990-12-18 Dual subcoated simulated capsule-like medicament

Country Status (15)

Country Link
US (2) US5198227A (en)
EP (1) EP0439315B1 (en)
JP (1) JP3091770B2 (en)
KR (1) KR100195570B1 (en)
AT (1) ATE110263T1 (en)
AU (1) AU633394B2 (en)
CA (1) CA2032592C (en)
DE (1) DE69103538T2 (en)
ES (1) ES2057749T3 (en)
GR (1) GR1002293B (en)
IE (1) IE64295B1 (en)
IN (1) IN171949B (en)
NZ (1) NZ236798A (en)
PT (1) PT96533B (en)
ZA (1) ZA91426B (en)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2104684A1 (en) * 1991-03-04 1992-09-05 Mahdi B. Fawzi Salts/ion pairs of non-steroidal anti-inflammatory drugs in various dosage forms
US6764697B1 (en) 1991-06-27 2004-07-20 Alza Corporation System for delaying drug delivery up to seven hours
GR1002332B (en) * 1992-05-21 1996-05-16 Mcneil-Ppc Inc. Novel simethicone containing pharmaceutical compositions.
US5472714A (en) * 1993-09-08 1995-12-05 Ciba-Geigy Corporation Double-layered oxcarbazepine tablets
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
US6245350B1 (en) 1994-12-16 2001-06-12 Warner-Lambert Company Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process
EP0797424B1 (en) * 1994-12-16 2000-07-12 Warner-Lambert Company Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process
US5776490A (en) * 1996-01-26 1998-07-07 The Center For Innovative Technology Complex protein-walled microcapsules containing lipid-walled microcapsules and method for producing same
JP3001440B2 (en) * 1996-11-25 2000-01-24 日本電気通信システム株式会社 Virtual LAN method
US5788987A (en) * 1997-01-29 1998-08-04 Poli Industria Chimica Spa Methods for treating early morning pathologies
US5891474A (en) 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
US8563522B2 (en) 1997-07-08 2013-10-22 The Iams Company Method of maintaining and/or attenuating a decline in quality of life
DE19849848A1 (en) * 1998-10-29 2000-05-04 Lohmann Therapie Syst Lts Oral application, spontaneous disintegration with liquid and dosage form and process for its preparation
US6211246B1 (en) 1999-06-10 2001-04-03 Mcneil-Ppc, Inc. Rapidly absorbed liquid compositions
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
US6656501B1 (en) 1999-09-01 2003-12-02 John T. Cooker Oral delivery system and method for making same
US20050079214A1 (en) * 1999-09-01 2005-04-14 John Cooker Oral delivery system and method for making same
US6254888B1 (en) 2000-01-28 2001-07-03 Boehringer Ingelheim Pharmaceuticals, Inc. Method for coating pharmaceutical dosage forms
US20070059367A1 (en) * 2000-06-06 2007-03-15 Cherukuri S R Drug Delivery System and Associated Methods
US7678387B2 (en) * 2000-06-06 2010-03-16 Capricorn Pharma, Inc. Drug delivery systems
US20100196466A1 (en) * 2000-06-06 2010-08-05 Capricorn Pharma Inc. Drug delivery system
AU2002220248A1 (en) * 2000-11-06 2002-05-15 Andrx Pharmaceuticals, Inc. Once a day antihistamine and decongestant formulation
JP2004529902A (en) * 2001-03-13 2004-09-30 ペンウェスト ファーマシューティカルズ カンパニー Chronotherapeutic dosage forms containing glucocorticosteroids
AU4061702A (en) * 2001-05-15 2003-04-03 Mcneil-Ppc, Inc. Dip coating compositions containing starch or dextrin
US20030072729A1 (en) * 2001-05-15 2003-04-17 Christopher Szymczak Simethicone as weight gain enhancer
US20030070584A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
US8309118B2 (en) * 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
US7169450B2 (en) * 2002-05-15 2007-01-30 Mcneil-Ppc, Inc. Enrobed core
US6946156B2 (en) * 2002-05-15 2005-09-20 Mcneil-Ppc, Inc. Process for enrobing a core
US7429619B2 (en) * 2002-08-02 2008-09-30 Mcneil Consumer Healthcare Polyacrylic film forming compositions
US8168170B2 (en) 2002-10-03 2012-05-01 The Procter And Gamble Company Compositions having an inner core and at least three surrounding layers
US8092831B2 (en) * 2002-11-08 2012-01-10 Andrx Pharmaceuticals, Llc Antihistamine and decongestant system
US20050118267A1 (en) * 2003-09-19 2005-06-02 Penwest Pharmaceuticals Co. Chronotherapeutic dosage forms
CN1882316A (en) * 2003-09-19 2006-12-20 宾韦斯特医药公司 Delayed release dosage forms
US7785635B1 (en) 2003-12-19 2010-08-31 The Procter & Gamble Company Methods of use of probiotic lactobacilli for companion animals
US8877178B2 (en) 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
US8894991B2 (en) 2003-12-19 2014-11-25 The Iams Company Canine probiotic Lactobacilli
US20050152884A1 (en) 2003-12-19 2005-07-14 The Procter & Gamble Company Canine probiotic Bifidobacteria globosum
US20050158294A1 (en) 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
WO2006130187A1 (en) 2005-05-31 2006-12-07 The Iams Company Feline probiotic lactobacilli
PL1885383T3 (en) 2005-05-31 2017-06-30 Iams Europe B.V. Feline probiotic bifidobacteria
UA95093C2 (en) 2005-12-07 2011-07-11 Нікомед Фарма Ас Method for the preparation of calcium-containing compound
JP5799299B2 (en) 2007-02-01 2015-10-21 ザ・アイムス・カンパニーＴｈｅ Ｉａｍｓ Ｃｏｍｐａｎｙ Method for reducing inflammation and stress in mammals using glucose antimetabolite, avocado or avocado extract
DE102007026037A1 (en) 2007-06-04 2008-12-11 Lts Lohmann Therapie-Systeme Ag Gastroretentive system with alginate body
KR20100087287A (en) * 2007-09-17 2010-08-04 맥네일-피피씨, 인코포레이티드 Dip coated compositions containing copolymer of polyvinyl alcohol and polyethylene glycol and a gum
BRPI0907832B8 (en) * 2008-02-19 2021-05-25 Mcneil Ppc Inc dip coated tablets containing a starch that has a high amylose content and its manufacturing process
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
WO2010071964A1 (en) * 2008-12-23 2010-07-01 Harmonium International Inc. Turbine coating apparatus and spray gun assembly therefor
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
JP6086857B2 (en) * 2013-11-15 2017-03-01 ティーエスフーズ株式会社 Frozen dumplings and method for producing frozen dumplings

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US599865A (en) * 1898-03-01 Emanuel l
US3185626A (en) * 1963-03-06 1965-05-25 Sterling Drug Inc Tablet coating method
DE2340060A1 (en) * 1973-08-08 1975-02-20 Scherer Gmbh R P GELATINE RESISTANT CAPSULES AND METHOD FOR MANUFACTURING THEREOF
IT1144911B (en) * 1981-03-19 1986-10-29 Pharmatec Spa CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION CONTAINING IBUPROFEN
IL70071A (en) * 1982-11-01 1987-12-31 Merrell Dow Pharma Multilayered sustained release pharmaceutical tablets having non-uniform distribution of active ingredient
CA1223209A (en) * 1983-04-07 1987-06-23 Thomas M. Tencza Capsule shaped tablets
US4571333A (en) * 1983-06-14 1986-02-18 Syntex (U.S.A.) Inc. Controlled release naproxen and naproxen sodium tablets
CA1217140A (en) * 1983-06-22 1987-01-27 Thomas M. Tencza Thin film coated tablets
EP0212746B1 (en) * 1985-08-16 1991-04-10 The Procter & Gamble Company Drug particles having constant release
US4928840A (en) * 1986-02-25 1990-05-29 American Home Products Corporation Tamper proof encapsulated medicaments
IT1200178B (en) * 1986-07-23 1989-01-05 Alfa Farmaceutici Spa GALENIC FORMULATIONS WITH SCHEDULED SALE CONTAINING DRUGS WITH ANTI-FLOGISTIC ACTIVITY
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
IT1201136B (en) * 1987-01-13 1989-01-27 Resa Farma TABLET FOR PHARMACEUTICAL USE SUITABLE FOR THE RELEASE OF SUBSTANCES OF ACTIVE SUBSTANCES
US4816259A (en) * 1987-02-12 1989-03-28 Chase Chemical Company, L.P. Process for coating gelatin capsules
US4966771A (en) * 1987-02-20 1990-10-30 Mcneilab, Inc. Gelatin coated caplets and process for making same
US4820524A (en) * 1987-02-20 1989-04-11 Mcneilab, Inc. Gelatin coated caplets and process for making same
GB8705083D0 (en) * 1987-03-04 1987-04-08 Euro Celtique Sa Spheroids
US4951230A (en) * 1987-10-26 1990-08-21 Tektronix, Inc. Method and apparatus for tiling an image
US4857337A (en) * 1988-05-24 1989-08-15 American Home Products Corp. (Del) Enteric coated aspirin tablets
ES2063317T3 (en) * 1989-12-29 1995-01-01 Bristol Myers Squibb Co COMBINATION OF CAPSULE AND LONG PILL.
US5089270A (en) * 1990-05-15 1992-02-18 L. Perrigo Company Capsule-shaped tablet
US5188688A (en) * 1990-07-20 1993-02-23 Minnesota Mining And Manufacturing Company Method of sealing a gelatin capsule
US5114720A (en) * 1990-12-27 1992-05-19 American Cyanamid Company Gelatin coated tablets and method for producing same

Also Published As

Publication number Publication date
AU633394B2 (en) 1993-01-28
DE69103538T2 (en) 1994-12-22
ES2057749T3 (en) 1994-10-16
US5296233A (en) 1994-03-22
NZ236798A (en) 1993-03-26
AU6989291A (en) 1991-07-25
IE64295B1 (en) 1995-07-26
JPH04210913A (en) 1992-08-03
US5198227A (en) 1993-03-30
PT96533B (en) 1998-07-31
ZA91426B (en) 1992-09-30
EP0439315B1 (en) 1994-08-24
GR910100028A (en) 1992-06-25
ATE110263T1 (en) 1994-09-15
IN171949B (en) 1993-02-13
PT96533A (en) 1991-10-15
CA2032592C (en) 1996-02-13
KR100195570B1 (en) 1999-06-15
IE910190A1 (en) 1991-07-31
KR910014110A (en) 1991-08-31
DE69103538D1 (en) 1994-09-29
EP0439315A1 (en) 1991-07-31
JP3091770B2 (en) 2000-09-25
GR1002293B (en) 1996-05-03

Similar Documents

Publication Publication Date Title
AU6989291A (en) Dual subcoated simulated capsule-like medicament
AU646399B2 (en) Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
IT1271122B (en) PHARMACEUTICAL COMPOSITIONS WITH OSMOTIC CONTROLLED RELEASE AND FOR DISSEMINATION OF THE DRUG AND PROCEDURE FOR THEIR PREPARATION
US5830503A (en) Enteric coated diltiazem once-a-day formulation
NZ336251A (en) Composition comprising a core layer (active ingredient, hydroxypropyl cellulose and microcrystalline cellulose), an inner layer (such as hydroxypropylmethyl cellulose, polyvinyl pyrolidore and lubricants; magnesium stearate or talc), an outer layer (hydroxypropylmethyl and hydroxypropyl cellulose)
ATE184196T1 (en) DELAYED-RELEASE MEDICINAL PRODUCTS CONTAINING DILTIAZEM
ID17428A (en) PHARMACEUTICAL PROPERTIES IN LAM SHAPE OF SHAPED CAPSULTURE, WHICH CAN BE REMOVED ON THE UNDERWATER CHANNEL OF DIGESTION
CA2208230A1 (en) Controlled release formulation (albuterol)
NO891052D0 (en) PHARMACEUTICAL PRODUCT FOR CONTROLLED RELEASE.
IT9019571A0 (en) THERAPEUTIC COMPOSITIONS WITH CONTROLLED RELEASE OF DRUGS SUPPORTED ON CROSS-LINKED POLYMERS AND COATED WITH POLYMER FILM, AND THEIR PREPARATION PROCESSES
SE8007639L (en) NEW TABLETS FOR DISSOLUTION IN THE BACKGROUND AND KITS FOR PRODUCING THEREOF
CA2068402A1 (en) Taste mask coatings for preparation of chewable pharmaceutical tablets
MX9707554A (en) Polysiloxane-comprising perfluoroalkyl ethers, and the preparation and use thereof.
EE03157B1 (en) Enantiomers of omeprazole, process for their preparation and pharmaceutical preparations containing them
NZ512683A (en) Taste-masked pharmaceutical particles that are suitable for making chewable tablets
HK1039070A1 (en) Pharmaceutical formulation comprising omeprazole
CA2170748A1 (en) Pharmaceutical preparations for the targeted treatment of crohn's disease and ulcerative colitis
ES8206179A1 (en) A process for producing a pharmaceutical capsule having enteric properties.
IE44540L (en) Controlled release tablet
CA2079934A1 (en) Taste mask coatings for preparing chewable pharmaceutical tablets
AU7267191A (en) Method for coating active principles with a ph-sensitive polymer
IT1230167B (en) PROCEDURE FOR FILM COATING OF PHARMACEUTICAL COMPOSITIONS WITH POLYMER DISPERSIONS.

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry