CA2040374A1 - Process for enhancing the resistance of aquatic animals to disease - Google Patents
Process for enhancing the resistance of aquatic animals to diseaseInfo
- Publication number
- CA2040374A1 CA2040374A1 CA2040374A CA2040374A CA2040374A1 CA 2040374 A1 CA2040374 A1 CA 2040374A1 CA 2040374 A CA2040374 A CA 2040374A CA 2040374 A CA2040374 A CA 2040374A CA 2040374 A1 CA2040374 A1 CA 2040374A1
- Authority
- CA
- Canada
- Prior art keywords
- aquatic animals
- provides
- enhancing
- disease
- resistance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/064—Saccharomycetales, e.g. baker's yeast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
Abstract
The present invention provides a process for stimulating the immune system of aquatic animals of the class Osteichthyes and subpbylum Crustacea comprising administering an effective amount of a yeast cell wall glucan composed of glucopyranose units linked by predominately beta-1,3 glycosidic bonds, having at least one branch therefrom of glucopyranose units linked by beta-1,6 glycosidic bonds. Additionally the invention provides a process for enhancing the effect of vaccines by administering an effective amount of the described yeast cell wall glucan along with vaccine antigens. Further this invention also provides a process for obtaining a glucan particularly effective for stimulating the immune system of aquatic animals of the class Osteichthyes and subphylum Crustacea.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54957590A | 1990-07-06 | 1990-07-06 | |
US07/549,575 | 1990-07-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2040374A1 true CA2040374A1 (en) | 1992-01-07 |
CA2040374C CA2040374C (en) | 1998-06-16 |
Family
ID=24193557
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002040374A Expired - Lifetime CA2040374C (en) | 1990-07-06 | 1991-04-12 | Process for enhancing the resistance of aquatic animals to disease |
Country Status (12)
Country | Link |
---|---|
US (1) | US5401727A (en) |
EP (1) | EP0466037B1 (en) |
JP (1) | JP2828799B2 (en) |
AT (1) | ATE160787T1 (en) |
AU (1) | AU628752B2 (en) |
CA (1) | CA2040374C (en) |
DE (1) | DE69128308T2 (en) |
DK (1) | DK0466037T3 (en) |
ES (1) | ES2109929T3 (en) |
FI (1) | FI104537B (en) |
GR (1) | GR3026130T3 (en) |
NO (1) | NO305705B1 (en) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0665649B2 (en) * | 1991-02-01 | 1994-08-24 | 台糖株式会社 | Crustacean biological defense enhancer, infectious disease preventive vaccine and feed |
JP3522772B2 (en) * | 1991-05-21 | 2004-04-26 | 台糖株式会社 | Vaccine immunopotentiator |
EP0640348A1 (en) * | 1993-07-26 | 1995-03-01 | Akzo Nobel N.V. | Oil-based and water-based adjuvant mixture |
DK0664671T3 (en) * | 1993-08-06 | 2003-01-06 | Biotec Pharmacon Asa | Animal feed comprising yeast glucan |
JPH08113539A (en) * | 1993-09-22 | 1996-05-07 | Nippon Paper Ind Co Ltd | Immunopotentiator, its production and feed for culturing crustaceans and fishes using the same |
NO300692B1 (en) * | 1994-04-29 | 1997-07-07 | Biotec Mackzymal As | Solubilized branched β-1,3-glucan and its use, as well as the use of unsolubilized branched β-1,3-glucan |
US5871751A (en) * | 1994-10-12 | 1999-02-16 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Renibacterium salmoninarum vaccine and method for its preparation |
JP3744020B2 (en) * | 1995-04-14 | 2006-02-08 | 日本製紙株式会社 | Immune enhancer and crustacean, fish and livestock feed containing the same |
ATE197225T1 (en) | 1995-09-05 | 2000-11-15 | Baensch Tetra Werke | ANTI-STRESS AGENTS FOR AQUATIC ANIMALS |
US5722346A (en) * | 1996-04-17 | 1998-03-03 | The Board Of Governors For Higher Education | Smolting feed |
US5786343A (en) * | 1997-03-05 | 1998-07-28 | Immudyne, Inc. | Phagocytosis activator compositions and their use |
WO1998047392A1 (en) * | 1997-04-18 | 1998-10-29 | Immudyne, Inc. | Gel delivery system for animal nutrition and health |
US7030101B2 (en) | 1998-09-14 | 2006-04-18 | Nabi Biopharmaceuticals | Compositions of β-glucans and specific antibodies |
EP1121135B1 (en) * | 1998-09-14 | 2009-01-28 | Nabi Biopharmaceuticals | Compositions of beta-glucans and specific immunoglobulins |
US20020009463A1 (en) * | 2000-02-23 | 2002-01-24 | Jan Raa | Novel, non-antigenic, mucosal adjuvant formulation which enhances the effects of substances, including vaccine antigens, in contact with mucosal body surfaces |
US20040127458A1 (en) * | 2000-11-06 | 2004-07-01 | Hunter Kenneth W. | Beta-glucan containing compositions, methods for manufacturing beta-glucans, and for manufacturing and using beta-glucans and conjugates thereof as vaccine adjuvants |
US8222232B2 (en) * | 2001-02-16 | 2012-07-17 | Cargill, Incorporated | Glucosamine and N-acetylglucosamine compositions and methods of making the same fungal biomass |
US7816514B2 (en) | 2001-02-16 | 2010-10-19 | Cargill, Incorporated | Glucosamine and method of making glucosamine from microbial biomass |
US7923437B2 (en) * | 2001-02-16 | 2011-04-12 | Cargill, Incorporated | Water soluble β-glucan, glucosamine, and N-acetylglucosamine compositions and methods for making the same |
US7323140B2 (en) * | 2001-03-28 | 2008-01-29 | Handylab, Inc. | Moving microdroplets in a microfluidic device |
US6939864B1 (en) | 2001-07-09 | 2005-09-06 | Purdue Research Foundation | Animal feed compositions and methods of using the same |
JPWO2003039567A1 (en) * | 2001-11-06 | 2005-02-24 | 株式会社オリエントキャンサーセラピー | Anticancer composition |
DE10222358A1 (en) * | 2002-05-21 | 2003-12-11 | Nutrinova Gmbh | ß-Glucan-containing sorbic acid preparation as a feed additive in livestock rearing |
US7018986B2 (en) * | 2002-09-20 | 2006-03-28 | Immudyne | Use of beta glucans for the treatment of osteoporosis and other diseases of bone resorption |
GB0225503D0 (en) * | 2002-11-01 | 2002-12-11 | Zoolife Internat Ltd | Gel feed |
GB0225502D0 (en) * | 2002-11-01 | 2002-12-11 | Zoolife Internat Ltd | Therapeutic and prophylactic preparations |
JP2004210895A (en) * | 2002-12-27 | 2004-07-29 | Immudyne Japan:Kk | METHOD FOR MANUFACTURING SOLUBLE beta-GLUCAN HAVING IMMUNE FUNCTION, AND ITS USE |
JP2007524354A (en) * | 2003-01-29 | 2007-08-30 | イミュダイン インコーポレーティッド | Immune enhancers for animals |
GB2399752A (en) * | 2003-03-26 | 2004-09-29 | Micap Plc | Pharmaceutical composition comprising a fungal cell or cell fragment as adjuvant |
SI1711058T1 (en) | 2004-01-23 | 2022-02-28 | Eden Research Plc, | Methods of killing nematodes comprising the application of a terpene component |
DK1753529T3 (en) | 2004-05-20 | 2013-11-11 | Eden Research Plc | Composition containing a hollow glucan particle or hollow cell wall particle encapsulating a terpene component, methods of preparing and using them |
US7740861B2 (en) * | 2004-06-16 | 2010-06-22 | University Of Massachusetts | Drug delivery product and methods |
WO2006032039A2 (en) | 2004-09-17 | 2006-03-23 | University Of Massachusetts | Compositions and their uses for lysosomal enzyme deficiencies |
US7306818B2 (en) * | 2005-01-03 | 2007-12-11 | Promd Biotech Co., Ltd. | Method for preventing and/or treating viral infection in aquatic animals |
WO2006121803A1 (en) | 2005-05-05 | 2006-11-16 | Sensient Flavors Inc. | Production of beta-glucans and mannans |
EP1948245B1 (en) * | 2005-10-24 | 2011-10-05 | University of Massachusetts | Compositions and their uses for gene therapy of bone conditions |
EP1954130B1 (en) | 2005-11-30 | 2018-06-13 | Eden Research Plc | Methods comprising terpene mixtures comprising thymol and citral |
BRPI0619219B8 (en) | 2005-11-30 | 2021-11-16 | Cornell Univ | Method for killing mites, method for treating or preventing infestation by a mite on a plant and use of a composition |
WO2008102151A1 (en) * | 2007-02-21 | 2008-08-28 | Biotec Pharmacon Asa | Medical uses of glucans |
JP5153188B2 (en) * | 2007-03-30 | 2013-02-27 | 小林製薬株式会社 | Th1 / Th2 balance improver |
US20090061049A1 (en) * | 2007-08-28 | 2009-03-05 | Vadood Azarm | Feed compositions for aquatic animals and methods of making the same |
EP2222283A2 (en) * | 2007-10-29 | 2010-09-01 | University of Massachusetts | Yeast cell wall protein (ycwp) encapsulated multilayered nanoparticles for nucleic acid delivery (sirna) |
CA2705642A1 (en) * | 2007-11-13 | 2009-05-22 | Biotec Pharmacon Asa | Methods of treating or preventing inflammatory diseases of the intestinal tract |
WO2009067020A1 (en) | 2007-11-19 | 2009-05-28 | Calanus As | Bioactive copepod-compositions, processes for the production thereof, and use thereof to prevent or treat hosts infested by phylogenetically similar ectoparasites |
US8815818B2 (en) | 2008-07-18 | 2014-08-26 | Rxi Pharmaceuticals Corporation | Phagocytic cell delivery of RNAI |
US9493774B2 (en) | 2009-01-05 | 2016-11-15 | Rxi Pharmaceuticals Corporation | Inhibition of PCSK9 through RNAi |
US20100267661A1 (en) * | 2009-03-17 | 2010-10-21 | Immudyne, Inc. | Beta glucans and methods of use thereof |
EP2550002B1 (en) | 2010-03-24 | 2019-05-08 | Phio Pharmaceuticals Corp. | Rna interference in dermal and fibrotic indications |
WO2011119871A1 (en) | 2010-03-24 | 2011-09-29 | Rxi Phrmaceuticals Corporation | Rna interference in ocular indications |
WO2012024229A1 (en) | 2010-08-14 | 2012-02-23 | University Of Massachusetts | Yeast cell wall particle for receptor-targeted nanoparticle delivery |
EP2694030A2 (en) | 2011-03-04 | 2014-02-12 | Sana Pharma AS | Cosmetic formulations |
GB201220940D0 (en) | 2012-11-21 | 2013-01-02 | Eden Research Plc | Method P |
EP3071031A1 (en) | 2013-11-21 | 2016-09-28 | Eden Research Plc | Pesticidal composition |
KR20160110370A (en) | 2013-12-04 | 2016-09-21 | 알엑스아이 파마슈티칼스 코포레이션 | Methods for treatment of wound healing utilizing chemically modified oligonucleotides |
US11279934B2 (en) | 2014-04-28 | 2022-03-22 | Phio Pharmaceuticals Corp. | Methods for treating cancer using nucleic acids targeting MDM2 or MYCN |
CA2947619A1 (en) | 2014-05-01 | 2015-11-05 | Rxi Pharmaceuticals Corporation | Methods for treatment of disorders in the front of the eye utilizing nucleic acid molecules |
CN107073294A (en) | 2014-09-05 | 2017-08-18 | 阿克赛医药公司 | Use the method for targeting TYR or MMP1 exonuclease treatment aging and skin disorder |
CA2970795A1 (en) | 2014-12-18 | 2016-06-23 | Alnylam Pharmaceuticals, Inc. | Reversir compounds |
GB201501793D0 (en) | 2015-02-03 | 2015-03-18 | Eden Research Plc | Encapsulation of high potency active agents |
US10808247B2 (en) | 2015-07-06 | 2020-10-20 | Phio Pharmaceuticals Corp. | Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach |
CA2991598A1 (en) | 2015-07-06 | 2017-01-12 | Rxi Pharmaceuticals Corporation | Nucleic acid molecules targeting superoxide dismutase 1 (sod1) |
EP3138573A1 (en) * | 2015-07-09 | 2017-03-08 | Danstar Ferment AG | Compositions and methods for stimulating immune responses in human and/or animal |
US11021707B2 (en) | 2015-10-19 | 2021-06-01 | Phio Pharmaceuticals Corp. | Reduced size self-delivering nucleic acid compounds targeting long non-coding RNA |
CN106719136A (en) * | 2016-11-30 | 2017-05-31 | 蚌埠市渔歌农业科技有限公司 | A kind of cultural method for preventing and treating catfish disease |
JP6530846B1 (en) * | 2018-10-09 | 2019-06-12 | アサヒグループホールディングス株式会社 | Immunostimulatory agent and method for preventing infection |
US20230002766A1 (en) | 2019-11-08 | 2023-01-05 | Phio Pharmaceuticals Corp. | Chemically modified oligonucleotides targeting bromodomain containing protein 4 (brd4) for immunotherapy |
CN117295502A (en) * | 2021-05-21 | 2023-12-26 | 朝日集团控股株式会社 | Immunostimulant and dextran compositions |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3301848A (en) * | 1962-10-30 | 1967-01-31 | Pillsbury Co | Polysaccharides and methods for production thereof |
GB2076418A (en) * | 1980-05-22 | 1981-12-02 | Sankyo Co | Hydrolyzed polysaccharide |
SE456911B (en) * | 1983-12-19 | 1988-11-14 | Olle Larm | WATER-SOLUBLE, AMINATED BETA-1,3-BUNDLE D-GLUCAN AND MACROPHAG STIMULATING COMPOSITION CONTAINING ITS SAME |
JPS6120561A (en) * | 1984-07-09 | 1986-01-29 | 住友ベークライト株式会社 | Medical adsorbent |
US4810646A (en) * | 1984-11-28 | 1989-03-07 | Massachusetts Institute Of Technology | Glucan compositions and process for preparation thereof |
US4739046A (en) * | 1985-08-19 | 1988-04-19 | Luzio Nicholas R Di | Soluble phosphorylated glucan |
JPS6337801A (en) * | 1986-07-31 | 1988-02-18 | Matsushita Electric Ind Co Ltd | Turn table |
CA1330303C (en) * | 1989-02-20 | 1994-06-21 | Libor Henry Nikl | Composition and process to enhance the efficacy of a fish vaccine |
-
1991
- 1991-04-12 CA CA002040374A patent/CA2040374C/en not_active Expired - Lifetime
- 1991-06-26 AU AU79338/91A patent/AU628752B2/en not_active Expired
- 1991-07-04 DE DE69128308T patent/DE69128308T2/en not_active Expired - Lifetime
- 1991-07-04 ES ES91111143T patent/ES2109929T3/en not_active Expired - Lifetime
- 1991-07-04 EP EP91111143A patent/EP0466037B1/en not_active Expired - Lifetime
- 1991-07-04 AT AT91111143T patent/ATE160787T1/en not_active IP Right Cessation
- 1991-07-04 JP JP3164603A patent/JP2828799B2/en not_active Expired - Lifetime
- 1991-07-04 DK DK91111143T patent/DK0466037T3/en active
- 1991-07-05 FI FI913275A patent/FI104537B/en not_active IP Right Cessation
- 1991-07-05 NO NO19912645A patent/NO305705B1/en not_active IP Right Cessation
-
1994
- 1994-02-02 US US08/190,435 patent/US5401727A/en not_active Expired - Lifetime
-
1998
- 1998-02-12 GR GR980400302T patent/GR3026130T3/en unknown
Also Published As
Publication number | Publication date |
---|---|
ATE160787T1 (en) | 1997-12-15 |
EP0466037A2 (en) | 1992-01-15 |
JP2828799B2 (en) | 1998-11-25 |
DE69128308T2 (en) | 1998-03-26 |
DE69128308D1 (en) | 1998-01-15 |
DK0466037T3 (en) | 1998-08-10 |
FI913275A0 (en) | 1991-07-05 |
EP0466037A3 (en) | 1992-10-28 |
ES2109929T3 (en) | 1998-02-01 |
NO305705B1 (en) | 1999-07-12 |
JPH04253703A (en) | 1992-09-09 |
AU628752B2 (en) | 1992-09-17 |
AU7933891A (en) | 1992-01-23 |
US5401727A (en) | 1995-03-28 |
CA2040374C (en) | 1998-06-16 |
FI104537B (en) | 2000-02-29 |
GR3026130T3 (en) | 1998-05-29 |
EP0466037B1 (en) | 1997-12-03 |
NO912645D0 (en) | 1991-07-05 |
FI913275A (en) | 1992-01-07 |
NO912645L (en) | 1992-01-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry | ||
MKEX | Expiry |
Effective date: 20110412 |