CA2060474A1 - Pharmaceutical use - Google Patents

Pharmaceutical use

Info

Publication number
CA2060474A1
CA2060474A1 CA2060474A CA2060474A CA2060474A1 CA 2060474 A1 CA2060474 A1 CA 2060474A1 CA 2060474 A CA2060474 A CA 2060474A CA 2060474 A CA2060474 A CA 2060474A CA 2060474 A1 CA2060474 A1 CA 2060474A1
Authority
CA
Canada
Prior art keywords
pharmaceutical use
methods
present
medical conditions
atherosclerosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2060474A
Other languages
French (fr)
Other versions
CA2060474C (en
Inventor
Lynette J. Dumble
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2060474A1 publication Critical patent/CA2060474A1/en
Application granted granted Critical
Publication of CA2060474C publication Critical patent/CA2060474C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins

Abstract

The present invention is concerned with methods for the treatment of medical conditions with benzindene prostaglandins. Medical conditions which may be treated by the methods of the present invention include transplant rejection and atherosclerosis.
CA002060474A 1992-01-27 1992-01-31 Pharmaceutical use Expired - Fee Related CA2060474C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US825,669 1992-01-27
US07/825,669 US5190972A (en) 1992-01-27 1992-01-27 Method of combatting cyclosporine organ toxicity with prostaglandin analogs

Publications (2)

Publication Number Publication Date
CA2060474A1 true CA2060474A1 (en) 1993-07-28
CA2060474C CA2060474C (en) 1998-04-28

Family

ID=25244639

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002060474A Expired - Fee Related CA2060474C (en) 1992-01-27 1992-01-31 Pharmaceutical use

Country Status (2)

Country Link
US (2) US5190972A (en)
CA (1) CA2060474C (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4430128A1 (en) * 1994-08-25 1996-02-29 Hoechst Ag Combination preparation with immunosuppressive, cardiovascular and cerebral effects
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
US20020006901A1 (en) * 1999-02-05 2002-01-17 Aldo T. Iacono Use of aerosolized cyclosporine for prevention and treatment of pulmonary disease
US6521212B1 (en) * 1999-03-18 2003-02-18 United Therapeutics Corporation Method for treating peripheral vascular disease by administering benzindene prostaglandins by inhalation
NZ531944A (en) * 2001-10-19 2006-03-31 Isotechnika Inc Synthesis of cyclosporin analogs
EP1499296B1 (en) * 2002-04-15 2012-04-04 MAP Pharmaceuticals Inc Formulation of fine particles using liquefied or dense gases
AR041089A1 (en) * 2003-05-15 2005-05-04 Merck & Co Inc PROCEDURE AND PHARMACEUTICAL COMPOSITIONS TO TREAT ATEROSCLEROSIS, DYSLIPIDEMIAS AND RELATED AFFECTIONS
US7417070B2 (en) 2003-05-22 2008-08-26 United Therapeutics Corporation Compounds and methods for delivery of prostacyclin analogs
US20090124697A1 (en) 2003-12-16 2009-05-14 United Therapeutics Corporation Inhalation formulations of treprostinil
ATE473736T1 (en) * 2003-12-16 2010-07-15 United Therapeutics Corp USE OF TREPROSTINIL FOR THE TREATMENT OF ISCHEMIC LESIONS
WO2015061720A2 (en) 2013-10-25 2015-04-30 Insmed Incorporated Prostacyclin compounds, compositions and methods of use thereof
US10343979B2 (en) 2014-11-18 2019-07-09 Insmed Incorporated Methods of manufacturing treprostinil and treprostinil derivative prodrugs
CN114072136A (en) 2019-04-29 2022-02-18 英斯梅德股份有限公司 Dry powder compositions of treprostinil prodrugs and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4100355A (en) * 1972-09-15 1978-07-11 The Upjohn Company 8β,12α-PGE2 -type compounds
US4205178A (en) * 1976-12-30 1980-05-27 The Upjohn Company 6-Keto prostaglandin E-type compounds
US4239778A (en) * 1978-09-12 1980-12-16 The University Of Illinois Foundation Azaprostanoic acid analogs and their use as inhibitors of platelet aggregation
US4306075A (en) * 1980-03-28 1981-12-15 The Upjohn Company Composition and process
JPH0240325A (en) * 1988-06-17 1990-02-09 Wellcome Found Ltd:The Pharmaceutical compound
US4977174A (en) * 1989-06-12 1990-12-11 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease

Also Published As

Publication number Publication date
US5321043A (en) 1994-06-14
US5190972A (en) 1993-03-02
CA2060474C (en) 1998-04-28

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Legal Events

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