CA2075966C - Implantable endocardial lead with retractable fixation apparatus - Google Patents
Implantable endocardial lead with retractable fixation apparatusInfo
- Publication number
- CA2075966C CA2075966C CA002075966A CA2075966A CA2075966C CA 2075966 C CA2075966 C CA 2075966C CA 002075966 A CA002075966 A CA 002075966A CA 2075966 A CA2075966 A CA 2075966A CA 2075966 C CA2075966 C CA 2075966C
- Authority
- CA
- Canada
- Prior art keywords
- lead
- tube
- electrode
- distal end
- assembly according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/056—Transvascular endocardial electrode systems
- A61N1/057—Anchoring means; Means for fixing the head inside the heart
- A61N1/0573—Anchoring means; Means for fixing the head inside the heart chacterised by means penetrating the heart tissue, e.g. helix needle or hook
Abstract
An implantable endocardial (10) lead with retractable sharpened helix (34). The piston (36) has a central bore (42) for re-ceiving a specialized stylet (44). The stylet comprises a flexible wire (56) having an enlarged distal end or tip (60). An elastomeric sliding tube (58) fits over the wire. When the proximal end of the stylet is inserted into the bore in the piston, the wire can be with-drawn slightly, pulling the enlarged tip into the tube, and wedging the tube against the walls of the bore. By manipulating the sty-let, the helix can be exposed outside of the lead, or retractable into the lead, as desired.
Description
- 2075~66 2 -1- PCr/US91/09306 IMPLANTABLE ENDOCARDIAL LEAD WITH
RETRACTABLE FIXATION APPARATUS
TECHNICAL FIELD
The present invention relates generally to cardiac stimulation, and more particularly to an implantable endocardial lead which stimulates or senses electrical activity of the heart and which employs a retractable fixation mechanism which can be repeatedly exposed to or shielded from tissue during the process of securing the 5 lead to cardiac tissue.
BACKGROUND ART
There are generally two types of body implantable leads used with cardiac pacemakers -- one which requires surgery to expose the myocardial tissue to which an electrode is affixed and another which can be inserted through a body vessel,10 such as a vein, into the heart where an electrode contacts the endocardial tissue.
In the latter type, the endocardial lead is often secured to the heart through the endothelial lining by a sharpened helix affixed to a distal end of the lead. When the end of the lead contacts the lining of the heart at a desired location, the lead may be secured in place by rotating the lead, thus screwing the helix into the heart1 5 tissue.
A helix system has been relatively effective in securing an endocardial lead once the initial location of the lead has been achieved. However, it is undesirable to expose the sharpened helix while the lead is being inserted through a blood vessel into the heart. Moreover, it is difficult to precisely place an endocardial lead 20 on the first attempt. It is common for a physician to repeatedly attempt to place an endocardial lead having a sharpened helix securing means. It is desireable, therefore, to be able to shield the sharpened helix during the insertion of the lead through the vein and between attempts to implant the lead on the heart lining. In WO92/11062 PCr/~'S91/0930, the prior art, various apparatus have been proposed for achieving the desired result.
For example, U.S.. Patent No. 3,974,834 to Lawrence M. Kane, discloses an implantable intervascular lead having an accordion-fold sleeve surrounding a helix.
The sleeve is retractable to expose the helix and re-expandable to cover the helix 5 in the event the helix is unscrewed and withdrawn. An object of the invention is to permit the lead to be inserted into and guided through a body vessel without snagging the body vessel.
Another attempt at solving these problems is disclosed in U.S. Patent No.
4,146,036 to Robert G. Dutcher and Albert S. Benjamin. This patent discloses a 10 body implantable, intervascular lead, having a helix fixation means. Apparatus for shielding the helix comprises a moveable piston or shaft located within the coils of the helix. The shaft is spring-loaded in a retracted position by the action of an elastomeric boot which also serves to seal off body fluids from the interior of the lead. A stylet passes through a lumen in the lead and acts against a proximal end 15 of the shaft to force the shaft forward through the helix thus forming a partial barrier and inhibiting the helix from coming in contact with tissue, at least in the axial direction.
In U.S. Patent No. 4,649,938 to William A. McArthur, an endocardial lead with an extendible/retractable helix fixation means is described. The helix is mounted on 20 a bobbin carried within the electrode tip. The bobbin and helix are retracted into the electrode tip by the action of a spring and are extended out of the tip by pressure from the end of the istylet inserted through a lumen in the lead.
B i 5~oS~o,S/6 -- In U.S. Patent No. (~orial numb~r 07/~32,1~2) to Paul R. Spehr, one of us described an endocardial lead with a flexible, tubular lanyard. The lanyard passed 25 through a lumen from a proximal end of the lead to a distal end of the lead, where the lanyard was attached to a sliding member supporting a helix. When the helix was in an exposed position, torque could be transmitted from the proximal end ofthe lanyard to the distal end thereof through a piston and thence to the helix to screw the helix into the endocardial tissue. To stiffen the lead during implantation, 30 a stylet could be inserted into the lumen in the lanyard. The invention of this later WO 92/11062 PCl/US91/09306 patent has been assigned to the same assignee as our present invention. The patent was designated as an improvement on an invention of James 1. Bradshaw, assigned to our same assignee and disclosed in U.S. Patent No. 4,913,164.
DISCLOSURE OF INVENTION
The present invention provides an implantable endocardial lead with retractable fixation means. In the preferred embodiment, the fixation means comprises a sharpened helix which can be repeatedly both retracted within an electrode at a distal end of the lead and displnced outside the electrode. The lead defines an lumen from its proximal to its distal end. A specialized stylet can be inserted into the lumen at the proximal end and passed through the lead to the distal end. Located at the distal end of the lead is a piston supporting a sharpened helix. The piston can be either free to rotate with respect to the lead, or constrained to slide along the axis of the lead. The piston has a central bore for receiving the specialized stylet.
The stylet comprises a flexible wire having an enlarged distal end or tip. An elastomeric sliding sleeve, preferably of polyamide, fits over the wire. When the proximal end of the stylet is inserted into the bore in the piston, the wire can be - withdrawn slightly, pulling the enlarged tip into the tube, and wedging the tube against the walls of the bore. By manipulating the stylet, the helix can be exposed outside of the lead or retracted into the lead, as desired.
It is a principal object of our present invention to provide an implantable endocardial lead with retractable fixation means wherein the fixation means can be repeatably shielded and exposed during the implantation process.
A further object of our invention is to provide a lead wherein the fixation means is selectively shielded within an electrode located at the distal end of the lead and wherein the fixation means is selectively exposed and shielded by the action of a two-part, removable stylet.
207~966 These and other objects and features of our invention will be apparent from the detailed description taken with reference to the accompanying drawings.
BRIEF DESCRIPTION OF DRAWINGS
FIG. 1 is a prospective view of an implantable endocardial lead according to our invention.
FIG. 2 is a sectional view of a distal tip of the lead taken along line 2-2 of FIG.
1.
BEST MODE FOR CARRYING OUT THE INVENTION
Reference is now made to the drawings, wherein like numerals designate like parts throughout. FIG. 1 shows an endocardial lead, generally designated 10. Thelead 10 has a suture sleeve 12 which slides along the lead 10 and which can be attached at an entrance into a vein of a patient in a conventional manner. The lead 10 also has an electrode 14 located at a distal end 16 of the lead.
As shown in FIG. 2, the lead 10 comprises a silicon or polyurethane sheath 18 which defines a lumen 20 along a longitudinal axis of the lead 10. Within thelumen 20, there is a coil conductor 22 for transmitting electrical impulses between the electrode 14 and a proximal end 24 of the lead 10. In the illustrated embodiment, a tri-filar conductor is shown as the coil conductor 22. The coil conductor 22 wraps around a crimp slug 26 at the distal end 16 of the lead 10.
The electrode 14 comprises a ring contact 28 and a conductive sleeve 30.
The conductive sleeve 30 fits over the crimp slug 26 and the coil conductor 22 and the three elements just mentioned are secured together by a crimp 32 in the conductive sleeve 30. The sheath 18 encloses the conductive sleeve 30 of the electrode 14 to the ring contact 28.
207$966 WO 92/11062 PCr/~S91/09306 In the illustrated embodiment, a fixation means is illustrated by a sharpened helix 34. A piston 36 supports the helix 34 in relatively constant alignment along the longitudinal axis of the lead 10. The piston 36 comprises a sliding member 38 whictl slidably engages the conductive sleeve 30. On the distal side of the piston 36, the sliding member 38 forms an cylinder 40 on which the helix 34 is mounted.
In our preferred embodiment, the sliding member 38 has an hexagonal outer edge 39 which engages an hexagonal inner edge 41 of the electrode 14. This permits the helix 34 to be rotated by rotating the entire lead. However, it is equally possible to omit this feature and permit the piston to rotate inside the electrode.
Torque would be applied to the helFx through a stylet, to be described hereafter.
Such a configuration would be especially well adapted for use in atrial leads, which frequently have a "J" shape which prevents the entire lead from being turned. The piston further comprises an interior bore 42 for receiving a stylet 44. At the proximal B side of the piston 36 we have provided a chamfered edge 46 so that the lanysrd 44 can be repeatedly inserted into the piston.
The stylet 44 passes through the lumen 20 in the lead 10 from the proximal end 24 to the distal end 16 thereof. In our preferred embodiment, the stylet 44 comprises a flexible wire 56 within a tube 58 of elastomeric material Preferably the tube is comprised of a material such as polyamide which is relatively incompressible and inextensible but flexible. The wire 56 has an enlarged distal tip 60. In our- preferred embodiment, the enlarged tip 60 is formed by soldering additional metal onto the end of the wire. An enlarged tip could also be formed by other means, such as flattening the wire. The outer diameter of the flattened section should be comparable to the outer diameter of the tube 58 and both should be sized to fit relatively easily into the bore 42 in the piston 36. The enlarged tip 60 should taper to the diameter of the wire 56 on at least the proximal side of the tip so that the trp can be forced into the tube with a wedging action whereby the stylet can be madeto grip interior walls 62 of the bore 42.
During implantation, the sharpened helix 34 can be repeatedly moved into and out of the electrode 14 until proper placement has been achieved. Then tt~e WO 92/11062 2 0 7 ~ 9 ~ 6 PCr/US91/0930~
physician can withdraw the stylet 44. The stylet 44 can be replaced in the lead or withdrawn theref,~,", as often as desired. It can also be replaced in the lead after the lead has be implanted for a period of time, should it become necessary to reposition the lead and if it is desired to retract the sharpened helix within the lead.
Our invention may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The present embodiment is therefore co"siclered in all aspects as illustrative and not restrictive the scope of the invention being indicated by the appended claims rather than by the foregoing description and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
RETRACTABLE FIXATION APPARATUS
TECHNICAL FIELD
The present invention relates generally to cardiac stimulation, and more particularly to an implantable endocardial lead which stimulates or senses electrical activity of the heart and which employs a retractable fixation mechanism which can be repeatedly exposed to or shielded from tissue during the process of securing the 5 lead to cardiac tissue.
BACKGROUND ART
There are generally two types of body implantable leads used with cardiac pacemakers -- one which requires surgery to expose the myocardial tissue to which an electrode is affixed and another which can be inserted through a body vessel,10 such as a vein, into the heart where an electrode contacts the endocardial tissue.
In the latter type, the endocardial lead is often secured to the heart through the endothelial lining by a sharpened helix affixed to a distal end of the lead. When the end of the lead contacts the lining of the heart at a desired location, the lead may be secured in place by rotating the lead, thus screwing the helix into the heart1 5 tissue.
A helix system has been relatively effective in securing an endocardial lead once the initial location of the lead has been achieved. However, it is undesirable to expose the sharpened helix while the lead is being inserted through a blood vessel into the heart. Moreover, it is difficult to precisely place an endocardial lead 20 on the first attempt. It is common for a physician to repeatedly attempt to place an endocardial lead having a sharpened helix securing means. It is desireable, therefore, to be able to shield the sharpened helix during the insertion of the lead through the vein and between attempts to implant the lead on the heart lining. In WO92/11062 PCr/~'S91/0930, the prior art, various apparatus have been proposed for achieving the desired result.
For example, U.S.. Patent No. 3,974,834 to Lawrence M. Kane, discloses an implantable intervascular lead having an accordion-fold sleeve surrounding a helix.
The sleeve is retractable to expose the helix and re-expandable to cover the helix 5 in the event the helix is unscrewed and withdrawn. An object of the invention is to permit the lead to be inserted into and guided through a body vessel without snagging the body vessel.
Another attempt at solving these problems is disclosed in U.S. Patent No.
4,146,036 to Robert G. Dutcher and Albert S. Benjamin. This patent discloses a 10 body implantable, intervascular lead, having a helix fixation means. Apparatus for shielding the helix comprises a moveable piston or shaft located within the coils of the helix. The shaft is spring-loaded in a retracted position by the action of an elastomeric boot which also serves to seal off body fluids from the interior of the lead. A stylet passes through a lumen in the lead and acts against a proximal end 15 of the shaft to force the shaft forward through the helix thus forming a partial barrier and inhibiting the helix from coming in contact with tissue, at least in the axial direction.
In U.S. Patent No. 4,649,938 to William A. McArthur, an endocardial lead with an extendible/retractable helix fixation means is described. The helix is mounted on 20 a bobbin carried within the electrode tip. The bobbin and helix are retracted into the electrode tip by the action of a spring and are extended out of the tip by pressure from the end of the istylet inserted through a lumen in the lead.
B i 5~oS~o,S/6 -- In U.S. Patent No. (~orial numb~r 07/~32,1~2) to Paul R. Spehr, one of us described an endocardial lead with a flexible, tubular lanyard. The lanyard passed 25 through a lumen from a proximal end of the lead to a distal end of the lead, where the lanyard was attached to a sliding member supporting a helix. When the helix was in an exposed position, torque could be transmitted from the proximal end ofthe lanyard to the distal end thereof through a piston and thence to the helix to screw the helix into the endocardial tissue. To stiffen the lead during implantation, 30 a stylet could be inserted into the lumen in the lanyard. The invention of this later WO 92/11062 PCl/US91/09306 patent has been assigned to the same assignee as our present invention. The patent was designated as an improvement on an invention of James 1. Bradshaw, assigned to our same assignee and disclosed in U.S. Patent No. 4,913,164.
DISCLOSURE OF INVENTION
The present invention provides an implantable endocardial lead with retractable fixation means. In the preferred embodiment, the fixation means comprises a sharpened helix which can be repeatedly both retracted within an electrode at a distal end of the lead and displnced outside the electrode. The lead defines an lumen from its proximal to its distal end. A specialized stylet can be inserted into the lumen at the proximal end and passed through the lead to the distal end. Located at the distal end of the lead is a piston supporting a sharpened helix. The piston can be either free to rotate with respect to the lead, or constrained to slide along the axis of the lead. The piston has a central bore for receiving the specialized stylet.
The stylet comprises a flexible wire having an enlarged distal end or tip. An elastomeric sliding sleeve, preferably of polyamide, fits over the wire. When the proximal end of the stylet is inserted into the bore in the piston, the wire can be - withdrawn slightly, pulling the enlarged tip into the tube, and wedging the tube against the walls of the bore. By manipulating the stylet, the helix can be exposed outside of the lead or retracted into the lead, as desired.
It is a principal object of our present invention to provide an implantable endocardial lead with retractable fixation means wherein the fixation means can be repeatably shielded and exposed during the implantation process.
A further object of our invention is to provide a lead wherein the fixation means is selectively shielded within an electrode located at the distal end of the lead and wherein the fixation means is selectively exposed and shielded by the action of a two-part, removable stylet.
207~966 These and other objects and features of our invention will be apparent from the detailed description taken with reference to the accompanying drawings.
BRIEF DESCRIPTION OF DRAWINGS
FIG. 1 is a prospective view of an implantable endocardial lead according to our invention.
FIG. 2 is a sectional view of a distal tip of the lead taken along line 2-2 of FIG.
1.
BEST MODE FOR CARRYING OUT THE INVENTION
Reference is now made to the drawings, wherein like numerals designate like parts throughout. FIG. 1 shows an endocardial lead, generally designated 10. Thelead 10 has a suture sleeve 12 which slides along the lead 10 and which can be attached at an entrance into a vein of a patient in a conventional manner. The lead 10 also has an electrode 14 located at a distal end 16 of the lead.
As shown in FIG. 2, the lead 10 comprises a silicon or polyurethane sheath 18 which defines a lumen 20 along a longitudinal axis of the lead 10. Within thelumen 20, there is a coil conductor 22 for transmitting electrical impulses between the electrode 14 and a proximal end 24 of the lead 10. In the illustrated embodiment, a tri-filar conductor is shown as the coil conductor 22. The coil conductor 22 wraps around a crimp slug 26 at the distal end 16 of the lead 10.
The electrode 14 comprises a ring contact 28 and a conductive sleeve 30.
The conductive sleeve 30 fits over the crimp slug 26 and the coil conductor 22 and the three elements just mentioned are secured together by a crimp 32 in the conductive sleeve 30. The sheath 18 encloses the conductive sleeve 30 of the electrode 14 to the ring contact 28.
207$966 WO 92/11062 PCr/~S91/09306 In the illustrated embodiment, a fixation means is illustrated by a sharpened helix 34. A piston 36 supports the helix 34 in relatively constant alignment along the longitudinal axis of the lead 10. The piston 36 comprises a sliding member 38 whictl slidably engages the conductive sleeve 30. On the distal side of the piston 36, the sliding member 38 forms an cylinder 40 on which the helix 34 is mounted.
In our preferred embodiment, the sliding member 38 has an hexagonal outer edge 39 which engages an hexagonal inner edge 41 of the electrode 14. This permits the helix 34 to be rotated by rotating the entire lead. However, it is equally possible to omit this feature and permit the piston to rotate inside the electrode.
Torque would be applied to the helFx through a stylet, to be described hereafter.
Such a configuration would be especially well adapted for use in atrial leads, which frequently have a "J" shape which prevents the entire lead from being turned. The piston further comprises an interior bore 42 for receiving a stylet 44. At the proximal B side of the piston 36 we have provided a chamfered edge 46 so that the lanysrd 44 can be repeatedly inserted into the piston.
The stylet 44 passes through the lumen 20 in the lead 10 from the proximal end 24 to the distal end 16 thereof. In our preferred embodiment, the stylet 44 comprises a flexible wire 56 within a tube 58 of elastomeric material Preferably the tube is comprised of a material such as polyamide which is relatively incompressible and inextensible but flexible. The wire 56 has an enlarged distal tip 60. In our- preferred embodiment, the enlarged tip 60 is formed by soldering additional metal onto the end of the wire. An enlarged tip could also be formed by other means, such as flattening the wire. The outer diameter of the flattened section should be comparable to the outer diameter of the tube 58 and both should be sized to fit relatively easily into the bore 42 in the piston 36. The enlarged tip 60 should taper to the diameter of the wire 56 on at least the proximal side of the tip so that the trp can be forced into the tube with a wedging action whereby the stylet can be madeto grip interior walls 62 of the bore 42.
During implantation, the sharpened helix 34 can be repeatedly moved into and out of the electrode 14 until proper placement has been achieved. Then tt~e WO 92/11062 2 0 7 ~ 9 ~ 6 PCr/US91/0930~
physician can withdraw the stylet 44. The stylet 44 can be replaced in the lead or withdrawn theref,~,", as often as desired. It can also be replaced in the lead after the lead has be implanted for a period of time, should it become necessary to reposition the lead and if it is desired to retract the sharpened helix within the lead.
Our invention may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The present embodiment is therefore co"siclered in all aspects as illustrative and not restrictive the scope of the invention being indicated by the appended claims rather than by the foregoing description and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Claims (10)
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. A lead assembly for implantation in a patient, the assembly comprising:
an electrode adapted for insertion into a chamber of the patient's heart for electrical stimulation thereof and having a lumen extending through the electrode from a proximal end to a distal end thereof;
a lead connected to said proximal end of the electrode at a distal end of the lead and adapted to transmit electrical impulses between the electrode and a proximal end of the lead, the lead having a lumen extending through the lead from the proximal end to the distal end thereof;
fixation means for securing the electrode to the lining of the heart chamber, the fixation means being in the lumen of the electrode and having a bore at a proximal side of said fixation means; and a stylet having a flexible tube and a flexible wire with an enlarged tip at a distal end of the wire, the wire being slidingly received within said flexible tube, the distal end of said wire and a distal end of said tube being adapted to be placed within said bore and the enlarged tip being adapted to be pulled into said tube to wedge the distal end of the stylet within the bore.
an electrode adapted for insertion into a chamber of the patient's heart for electrical stimulation thereof and having a lumen extending through the electrode from a proximal end to a distal end thereof;
a lead connected to said proximal end of the electrode at a distal end of the lead and adapted to transmit electrical impulses between the electrode and a proximal end of the lead, the lead having a lumen extending through the lead from the proximal end to the distal end thereof;
fixation means for securing the electrode to the lining of the heart chamber, the fixation means being in the lumen of the electrode and having a bore at a proximal side of said fixation means; and a stylet having a flexible tube and a flexible wire with an enlarged tip at a distal end of the wire, the wire being slidingly received within said flexible tube, the distal end of said wire and a distal end of said tube being adapted to be placed within said bore and the enlarged tip being adapted to be pulled into said tube to wedge the distal end of the stylet within the bore.
2. The lead assembly according to claim 1 wherein the fixation means comprises a sharpened helix.
3. The lead assembly according to claim 2 further comprising means for preventing the sharpened helix from rotating with respect to the electrode.
4. The lead assembly according to claim 3 wherein the rotation preventing means comprise an hexagonal inner surface on the electrode and a mating hexagonal outer surface on the fixation means.
5. The lead assembly according to claim 1 wherein the flexible tube comprises a polyamide tube.
6. The lead assembly according to claim 1 wherein the enlarged tip comprises a soldered metal bulb.
7. The lead assembly according to claim 6 wherein the metal bulb has an outside diameter substantially equal to an outside diameter of said tube.
8. The lead assembly according to claim 7 wherein the metal bulb comprises a tapered proximal edge adapted to wedge into said tube.
9. The lead assembly according to claim 1 wherein the enlarged tip has an outside diameter substantially equal to an outside diameter of said tube.
10. The lead assembly according to claim 9 wherein the enlarged tip comprises a tapered proximal edge adapted to wedge into said tube.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US635,760 | 1990-12-21 | ||
| US07/635,760 US5129404A (en) | 1990-12-21 | 1990-12-21 | Implantable endocardial lead with retractable fixation apparatus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2075966A1 CA2075966A1 (en) | 1992-06-22 |
| CA2075966C true CA2075966C (en) | 1997-01-07 |
Family
ID=24549014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002075966A Expired - Fee Related CA2075966C (en) | 1990-12-21 | 1991-12-06 | Implantable endocardial lead with retractable fixation apparatus |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5129404A (en) |
| EP (1) | EP0516820B1 (en) |
| JP (1) | JPH05505756A (en) |
| CA (1) | CA2075966C (en) |
| DE (1) | DE69116866T2 (en) |
| ES (1) | ES2083155T3 (en) |
| WO (1) | WO1992011062A1 (en) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5228455A (en) * | 1991-05-20 | 1993-07-20 | Siemens Pacesetter, Inc. | Implant tool for extendable/retractable positive fixation lead |
| US5291896A (en) * | 1991-08-21 | 1994-03-08 | Baxter International Inc. | Cardiac output probe assembly |
| US5496362A (en) * | 1992-11-24 | 1996-03-05 | Cardiac Pacemakers, Inc. | Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation |
| US5300108A (en) * | 1993-01-05 | 1994-04-05 | Telectronics Pacing Systems, Inc. | Active fixation lead with a dual-pitch, free spinning compound screw |
| US5593433A (en) * | 1994-12-19 | 1997-01-14 | Intermedics, Inc. | Implantable endocardial lead with self-healing retractable fixation apparatus |
| US5571161A (en) * | 1995-04-12 | 1996-11-05 | Starksen; Niel F. | Apparatus and method for implanting electrical leads in the heart |
| US5716391A (en) * | 1995-08-23 | 1998-02-10 | Medtronic, Inc. | Medical electrical lead having temporarily rigid fixation |
| DE29603805U1 (en) * | 1996-03-01 | 1997-07-03 | Michel Ulrich Dipl Ing | Device for transvenous cardioversion of atrial fibrillation or atrial flutter |
| US5843153A (en) * | 1997-07-15 | 1998-12-01 | Sulzer Intermedics Inc. | Steerable endocardial lead using magnetostrictive material and a magnetic field |
| US5876431A (en) * | 1997-07-30 | 1999-03-02 | Sulzer Intermedics Inc. | Small cable endocardial lead with exposed guide tube |
| US6324415B1 (en) | 1997-07-30 | 2001-11-27 | Intermedics Inc. | Cardiac lead with minimized inside diameter of sleeve |
| US5851227A (en) * | 1997-07-30 | 1998-12-22 | Sulzer Intermedics Inc. | Cardiac pacemaker cable lead |
| US6321122B1 (en) | 1998-07-22 | 2001-11-20 | Cardiac Pacemakers, Inc. | Single pass defibrillation/pacing lead with passively attached electrode for pacing and sensing |
| US6085119A (en) * | 1998-07-22 | 2000-07-04 | Cardiac Pacemakers, Inc. | Single pass endocardial lead for multi-site atrial pacing |
| US6212434B1 (en) | 1998-07-22 | 2001-04-03 | Cardiac Pacemakers, Inc. | Single pass lead system |
| US6097986A (en) * | 1997-12-17 | 2000-08-01 | Cardiac Pacemakers, Inc. | Retractable lead with mesh screen |
| US6152954A (en) | 1998-07-22 | 2000-11-28 | Cardiac Pacemakers, Inc. | Single pass lead having retractable, actively attached electrode for pacing and sensing |
| US6501994B1 (en) | 1997-12-24 | 2002-12-31 | Cardiac Pacemakers, Inc. | High impedance electrode tip |
| US6047217A (en) * | 1998-01-15 | 2000-04-04 | Intermedics Inc. | Cardiac lead with improved polymer-to-metal joint |
| US5908447A (en) * | 1998-02-06 | 1999-06-01 | Intermedics Inc. | Breakaway structure for body implantable medical device |
| US6148237A (en) * | 1998-03-06 | 2000-11-14 | Intermedics Inc. | Cardiac pacemaker lead with swaged distal electrode |
| US6167314A (en) * | 1998-04-14 | 2000-12-26 | Intermedics Inc. | Cardiac pacemaker lead with pacemaker connector |
| US6108582A (en) * | 1998-07-02 | 2000-08-22 | Intermedics Inc. | Cardiac pacemaker lead with extendable/retractable fixation |
| US6463334B1 (en) | 1998-11-02 | 2002-10-08 | Cardiac Pacemakers, Inc. | Extendable and retractable lead |
| US6501990B1 (en) | 1999-12-23 | 2002-12-31 | Cardiac Pacemakers, Inc. | Extendable and retractable lead having a snap-fit terminal connector |
| US6129751A (en) * | 1998-07-28 | 2000-10-10 | Intermedics Inc. | Cardiac lead with active fixation and biocompatible lubricant |
| US6002969A (en) * | 1998-08-05 | 1999-12-14 | Intermedics Inc. | Cardiac lead with shape-memory structure |
| US6083216A (en) * | 1999-01-05 | 2000-07-04 | Intermedics Inc. | Bent cardiac lead with shape memory torque coil |
| US7013182B1 (en) | 2000-05-04 | 2006-03-14 | Cardiac Pacemakers, Inc. | Conductive polymer sheath on defibrillator shocking coils |
| EP1188762A1 (en) * | 2000-09-14 | 2002-03-20 | Solvay Polyolefins Europe-Belgium (Société Anonyme) | Chromium complexes and their use for the polymerization of alpha-olefins |
| US6512959B1 (en) | 2000-11-28 | 2003-01-28 | Pacesetter, Inc. | Double threaded stylet for extraction of leads with a threaded electrode |
| US6611710B2 (en) | 2000-11-29 | 2003-08-26 | Pacesetter, Inc. | Double threaded stylet for extraction of leads with a threaded electrode |
| US6763270B1 (en) | 2001-08-07 | 2004-07-13 | Pacesetter, Inc. | Lead extraction mechanism for active fixation leads |
| US6842649B2 (en) | 2001-12-14 | 2005-01-11 | Cardiac Pacemakers, Inc. | Snap-spin lead assembly and method therefor |
| FR2835189B1 (en) | 2002-01-25 | 2004-03-19 | Ela Medical Sa | NECESSARY TO SET UP AN INTRACARDIAC STIMULATION OR DEFIBRILLATION PROBE OF THE RETRACTABLE SCREW TYPE |
| US6970748B2 (en) | 2002-04-04 | 2005-11-29 | Cardiac Pacemakers, Inc. | Method of using finishing wire with large ball-nose tip |
| US7509172B2 (en) * | 2003-04-23 | 2009-03-24 | Cardiac Pacemakers, Inc. | Stabilizing guide wire apparatus for use with implantable device |
| US20040260371A1 (en) * | 2003-06-19 | 2004-12-23 | John Greenland | Stabilizing apparatus for use with implantable leads |
| US7245973B2 (en) | 2003-12-23 | 2007-07-17 | Cardiac Pacemakers, Inc. | His bundle mapping, pacing, and injection lead |
| US7181290B2 (en) * | 2004-03-12 | 2007-02-20 | Pacesetter, Inc. | Convertible stylet to abet in the implant of a left heart lead |
| US8326423B2 (en) | 2004-12-20 | 2012-12-04 | Cardiac Pacemakers, Inc. | Devices and methods for steering electrical stimulation in cardiac rhythm management |
| US8010191B2 (en) | 2004-12-20 | 2011-08-30 | Cardiac Pacemakers, Inc. | Systems, devices and methods for monitoring efficiency of pacing |
| US8010192B2 (en) | 2004-12-20 | 2011-08-30 | Cardiac Pacemakers, Inc. | Endocardial pacing relating to conduction abnormalities |
| US8423139B2 (en) | 2004-12-20 | 2013-04-16 | Cardiac Pacemakers, Inc. | Methods, devices and systems for cardiac rhythm management using an electrode arrangement |
| US8005544B2 (en) | 2004-12-20 | 2011-08-23 | Cardiac Pacemakers, Inc. | Endocardial pacing devices and methods useful for resynchronization and defibrillation |
| AR047851A1 (en) | 2004-12-20 | 2006-03-01 | Giniger Alberto German | A NEW MARCAPASOS THAT RESTORES OR PRESERVES THE PHYSIOLOGICAL ELECTRIC DRIVING OF THE HEART AND A METHOD OF APPLICATION |
| US8290586B2 (en) | 2004-12-20 | 2012-10-16 | Cardiac Pacemakers, Inc. | Methods, devices and systems for single-chamber pacing using a dual-chamber pacing device |
| US7983764B2 (en) * | 2005-08-12 | 2011-07-19 | Cardiac Pacemakers, Inc. | Co-radial lead with extendable/retractable fixation mechanism and apparatus therefor |
| AU2006279641A1 (en) * | 2005-08-15 | 2007-02-22 | Synecor, Llc | Lead fixation and extraction |
| US7881808B2 (en) * | 2006-03-29 | 2011-02-01 | Cardiac Pacemakers, Inc. | Conductive polymeric coating with optional biobeneficial topcoat for a medical lead |
| US8200343B2 (en) * | 2006-04-27 | 2012-06-12 | Medtronic, Inc. | Implantable medical electrical stimulation lead fixation method and apparatus |
| US8135476B2 (en) * | 2006-04-27 | 2012-03-13 | Medtronic, Inc. | Implantable medical electrical stimulation lead fixation method and apparatus |
| US8145323B2 (en) * | 2006-04-27 | 2012-03-27 | Medtronic, Inc. | Implantable medical electrical stimulation lead fixation method and apparatus |
| US8204569B2 (en) * | 2006-04-27 | 2012-06-19 | Medtronic, Inc. | Implantable medical electrical stimulation lead fixation method and apparatus |
| US9480800B2 (en) | 2006-09-11 | 2016-11-01 | Custom Medical Applications | Neural injection system and related methods |
| US20080065029A1 (en) * | 2006-09-11 | 2008-03-13 | Racz N S | Nerve block needle and related methods |
| US8449503B2 (en) | 2010-11-30 | 2013-05-28 | Custom Medical Applications | Neural injection system and related methods |
| US9888940B2 (en) | 2006-09-11 | 2018-02-13 | Custom Medical Applications | Neural injection system and related methods |
| US8377005B2 (en) | 2006-09-11 | 2013-02-19 | Custom Medical Applications | Neural injection system and related methods |
| US7657326B2 (en) * | 2006-11-08 | 2010-02-02 | Cardiac Pacemakers, Inc. | Cardiac lead with a retractable helix |
| US8690832B2 (en) | 2007-06-13 | 2014-04-08 | Custom Medical Applications | Retrofitted neural injection system and related methods |
| US20090259283A1 (en) * | 2008-04-09 | 2009-10-15 | Brandt Michael S | Sheathed lead for pacing or defibrillation |
| US8108052B2 (en) | 2008-05-29 | 2012-01-31 | Nervo Corporation | Percutaneous leads with laterally displaceable portions, and associated systems and methods |
| WO2010071849A2 (en) | 2008-12-19 | 2010-06-24 | Action Medical, Inc. | Devices, methods, and systems including cardiac pacing |
| WO2010081132A1 (en) * | 2009-01-12 | 2010-07-15 | University Of Massachusetts Lowell | Polyisobutylene-based polyurethanes |
| JP5602859B2 (en) | 2009-08-21 | 2014-10-08 | カーディアック ペースメイカーズ， インコーポレイテッド | POLYISOBUTYLENE-BASED CROSSLINKABLE POLYMER AND MEDICAL DEVICE CONTAINING THE SAME |
| US8644952B2 (en) | 2009-09-02 | 2014-02-04 | Cardiac Pacemakers, Inc. | Medical devices including polyisobutylene based polymers and derivatives thereof |
| US8374704B2 (en) | 2009-09-02 | 2013-02-12 | Cardiac Pacemakers, Inc. | Polyisobutylene urethane, urea and urethane/urea copolymers and medical leads containing the same |
| US8565880B2 (en) | 2010-04-27 | 2013-10-22 | Cardiac Pacemakers, Inc. | His-bundle capture verification and monitoring |
| CN104520345B (en) | 2012-11-21 | 2017-10-03 | 马萨诸塞州大学 | The poly- poly- mephenesin Carbamate of ammonia isobutene of high intensity |
| US9308022B2 (en) | 2012-12-10 | 2016-04-12 | Nevro Corporation | Lead insertion devices and associated systems and methods |
| CN110382568B (en) | 2017-03-07 | 2022-03-04 | 心脏起搏器股份公司 | Hydroboration/oxidation of allyl-terminated polyisobutylenes |
| AU2018231031B2 (en) | 2017-03-09 | 2023-11-02 | Nevro Corp. | Paddle leads and delivery tools, and associated systems and methods |
| US10835638B2 (en) | 2017-08-17 | 2020-11-17 | Cardiac Pacemakers, Inc. | Photocrosslinked polymers for enhanced durability |
| CN111479596B (en) | 2018-01-17 | 2023-04-07 | 心脏起搏器股份公司 | Blocked polyisobutylene polyurethanes |
| AU2019242906A1 (en) | 2018-03-29 | 2020-10-15 | Nevro Corp. | Leads having sidewall openings, and associated systems and methods |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4217913A (en) * | 1977-10-10 | 1980-08-19 | Medtronic, Inc. | Body-implantable lead with protected, extendable tissue securing means |
| US4209019A (en) * | 1979-01-05 | 1980-06-24 | Medtronic, Inc. | Stylet insertion guide and rotation control device for use with body implantable lead |
| US5003992A (en) * | 1989-08-23 | 1991-04-02 | Holleman Timothy W | Atraumatic screw-in lead |
-
1990
- 1990-12-21 US US07/635,760 patent/US5129404A/en not_active Expired - Lifetime
-
1991
- 1991-12-06 JP JP92503170A patent/JPH05505756A/en active Pending
- 1991-12-06 CA CA002075966A patent/CA2075966C/en not_active Expired - Fee Related
- 1991-12-06 ES ES92903179T patent/ES2083155T3/en not_active Expired - Lifetime
- 1991-12-06 EP EP92903179A patent/EP0516820B1/en not_active Expired - Lifetime
- 1991-12-06 WO PCT/US1991/009306 patent/WO1992011062A1/en active IP Right Grant
- 1991-12-06 DE DE69116866T patent/DE69116866T2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1992011062A1 (en) | 1992-07-09 |
| ES2083155T3 (en) | 1996-04-01 |
| JPH05505756A (en) | 1993-08-26 |
| CA2075966A1 (en) | 1992-06-22 |
| US5129404A (en) | 1992-07-14 |
| EP0516820B1 (en) | 1996-01-31 |
| DE69116866T2 (en) | 1996-09-05 |
| EP0516820A1 (en) | 1992-12-09 |
| DE69116866D1 (en) | 1996-03-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2075966C (en) | Implantable endocardial lead with retractable fixation apparatus | |
| US4924881A (en) | Implantable endocardial lead with fixation device retractable by threaded stylet | |
| US4967766A (en) | Implantable endocardial lead with fixation apparatus retractable by a lanyard | |
| US5056516A (en) | Implantable endocordial lead with torque-transmitting lanyard | |
| US5593433A (en) | Implantable endocardial lead with self-healing retractable fixation apparatus | |
| US5152299A (en) | Implantable endocardial lead with spring-loaded screw-in fixation apparatus | |
| CA2194744C (en) | Active fixation medical electrical lead having improved turning tool | |
| DE69726585T2 (en) | LIMITING THE RESET STROKE FOR A MEDICAL SCREW ELECTRODE | |
| US5522875A (en) | Medical electrical lead system having a torque transfer stylet | |
| US4624266A (en) | Introducer tool for screw-in lead | |
| US4282885A (en) | Electrode for implantation in the heart | |
| US5228455A (en) | Implant tool for extendable/retractable positive fixation lead | |
| US4570642A (en) | Endocardial extendable screw-in lead | |
| US4146036A (en) | Body-implantable lead with protector for tissue securing means | |
| US5575814A (en) | Active fixation medical electrical lead having mapping capability | |
| US5716390A (en) | Reduced diameter active fixation pacing lead using concentric interleaved coils | |
| US5246014A (en) | Implantable lead system | |
| US9108043B2 (en) | Bipolar screw-in lead | |
| US6038463A (en) | Medical electrical lead | |
| US6016436A (en) | Medical electrical lead | |
| US6819959B1 (en) | Extendable/retractable screw-in tip design with an improved thread/screw mechanism | |
| US4136701A (en) | Retractable stimulation electrode apparatus | |
| US7031774B1 (en) | Switch for electrode selections in Single-pass Atrial/Ventricular leads | |
| EP0715865A2 (en) | Steerable stylet assembly | |
| EP0041254A1 (en) | Implantable pacemaker leads |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |