CA2112805A1 - Use of unpigmented fish skin, particularly from flat fish, as a novel industrial source of collagen, extraction method, and collagen and biomaterial thereby obtained - Google Patents
Use of unpigmented fish skin, particularly from flat fish, as a novel industrial source of collagen, extraction method, and collagen and biomaterial thereby obtainedInfo
- Publication number
- CA2112805A1 CA2112805A1 CA002112805A CA2112805A CA2112805A1 CA 2112805 A1 CA2112805 A1 CA 2112805A1 CA 002112805 A CA002112805 A CA 002112805A CA 2112805 A CA2112805 A CA 2112805A CA 2112805 A1 CA2112805 A1 CA 2112805A1
- Authority
- CA
- Canada
- Prior art keywords
- collagen
- fish
- skin
- unpigmented
- biomaterial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L89/00—Compositions of proteins; Compositions of derivatives thereof
- C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
- C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
- C08H1/00—Macromolecular products derived from proteins
- C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/855—Proteins from animals other than mammals or birds
- Y10S530/857—Fish; fish eggs; shell fish; crustacea
Abstract
The present invention relates to a process for the extraction of native collagen from non-pigmented fish skin which is preferably a flat fish skin. As non-pigmented skin, the ventral skin is used in particular, from sole, dab, turbot and brill.
Native acid-soluble collagen is advantageously extracted and separated by precipitation from the supernatant. The invention makes it possible to improve the collagen yield at reduced cost while preserving the native properties of the protein, and in reproducible manner.
Native acid-soluble collagen is advantageously extracted and separated by precipitation from the supernatant. The invention makes it possible to improve the collagen yield at reduced cost while preserving the native properties of the protein, and in reproducible manner.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9108400A FR2678624A1 (en) | 1991-07-04 | 1991-07-04 | USE OF NON-PIGMENTED FISH SKIN, ESPECIALLY FLAT FISH AS A NEW INDUSTRIAL SOURCE OF COLLAGEN, EXTRACTION PROCESS, COLLAGEN AND BIOMATERIAL OBTAINED THEREBY. |
FR91/08400 | 1991-07-04 | ||
PCT/FR1992/000621 WO1993001241A1 (en) | 1991-07-04 | 1992-07-02 | Use of unpigmented fish skin, particularly from flat fish, as a novel industrial source of collagen, extraction method, and collagen and biomaterial thereby obtained |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2112805A1 true CA2112805A1 (en) | 1993-01-21 |
CA2112805C CA2112805C (en) | 2001-04-24 |
Family
ID=9414727
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002112805A Expired - Lifetime CA2112805C (en) | 1991-07-04 | 1992-07-02 | Use of unpigmented fish skin, particularly from flat fish, as a novel industrial source of collagen, extraction method, and collagen and biomaterial thereby obtained |
Country Status (9)
Country | Link |
---|---|
US (1) | US5420248A (en) |
EP (1) | EP0592586B1 (en) |
JP (1) | JP2722014B2 (en) |
AT (1) | ATE157386T1 (en) |
CA (1) | CA2112805C (en) |
DE (1) | DE69221872T2 (en) |
ES (1) | ES2108759T3 (en) |
FR (1) | FR2678624A1 (en) |
WO (1) | WO1993001241A1 (en) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2714063B1 (en) * | 1993-12-20 | 1996-03-08 | Javenech | Process for the preparation of collagen from cnidarians, and compositions obtained which can be used in cosmetics. |
GB9405219D0 (en) * | 1994-03-17 | 1994-04-27 | Vickers James Ltd | Collagen finings and preparation thereof |
JP2731833B2 (en) * | 1995-06-26 | 1998-03-25 | 大同ほくさん株式会社 | Substitute skin made from marine life |
US6271350B1 (en) * | 1998-08-11 | 2001-08-07 | Thara & Company Ltd. | Fish collagen and method of producing same |
JP2931814B1 (en) * | 1998-08-11 | 1999-08-09 | 井原水産株式会社 | Method for producing fish collagen |
FR2787968B1 (en) * | 1998-12-31 | 2001-03-23 | Skw Biosystems | PROCESS FOR THE PREPARATION OF FISH GELATIN |
FR2801313A1 (en) * | 1999-05-19 | 2001-05-25 | Coletica | COLLAGENIC PRODUCT CONTAINING COLLAGEN OF MARINE ORIGIN WITH LOW ODOR AND PREFERREDLY WITH IMPROVED MECHANICAL PROPERTIES, AS WELL AS ITS USE IN THE FORM OF COMPOSITIONS OR COSMETIC OR PHARMACEUTICAL PRODUCTS |
NZ501386A (en) * | 1999-11-29 | 2002-10-25 | Nz Inst For Crop & Food Res | Collagen from fish skin |
WO2001091821A1 (en) * | 2000-05-26 | 2001-12-06 | Coletica | Collagen-based supports for tissue engineering and preparation of biomaterials |
FR2809313B1 (en) * | 2000-05-26 | 2005-11-18 | Coletica | PROCESSES FOR THE PREPARATION OF NEW COLLAGEN-BASED MEDIA FOR TISSUE ENGINEERING AND BIOMATERIALS OBTAINED |
FR2809314B1 (en) * | 2000-05-26 | 2005-11-18 | Coletica | USE OF COLLAGEN OF AQUATIC ORIGIN FOR THE PRODUCTION OF SUBSTANCES FOR TISSUE ENGINEERING, AND SUPPORTS AND BIOMATERIALS OBTAINED |
US6790454B1 (en) | 2000-05-26 | 2004-09-14 | Coletica | Processes for the preparation of novel collagen-based supports for tissue engineering, and biomaterials obtained |
US6974679B2 (en) * | 2000-05-26 | 2005-12-13 | Coletica | Support with collagen base for tissue engineering and manufacture of biomaterials |
FR2809412A1 (en) | 2000-05-26 | 2001-11-30 | Coletica | Use of aquatic collagen for making supports for tissue engineering, particularly skin or tissue equivalents for surgical repair, studying aging processes and screening |
JP3747412B2 (en) * | 2000-05-26 | 2006-02-22 | エンゲルハード・リヨン | Use of collagen from aquatic animals to produce carriers designed for tissue engineering and the carriers and biomaterials obtained thereby |
KR20020036225A (en) * | 2000-11-09 | 2002-05-16 | 이종윤 | Biomembrane Dressing for Healing Dermal Wound and Infection |
ES2212870B1 (en) * | 2001-08-08 | 2005-10-01 | Consejo Superior De Investigaciones Cientificas | STABILIZATION FOR THE CONSERVATION AND STORAGE IN THE ENVIRONMENTAL TEMPERATURE OF SKIN AND CONNECTIVE FISH FABRIC, AND AFTER PRODUCTION OF COLLAGEN AND / OR GELATINE. |
US20040078601A1 (en) * | 2002-08-02 | 2004-04-22 | Chris Tengwall | System and method for operating a wireless device network |
PL190737B1 (en) * | 2002-10-15 | 2006-01-31 | Przybylski Jozef Edward | Method of receiving biologically active collagen from the skin of fish of salmon family |
JP2005087440A (en) * | 2003-09-17 | 2005-04-07 | Matsumoto Shika Univ | Composition containing raw material of marine organism and production method of the composition |
JP2005095331A (en) * | 2003-09-24 | 2005-04-14 | Ihara Suisan Kk | Foamed body sheet containing fishskin dermal collagen and its use |
US20090312524A1 (en) * | 2003-11-28 | 2009-12-17 | Alternative Sourced Collagen, Llc | Compositions and methods comprising collagen |
US7109300B2 (en) | 2004-04-19 | 2006-09-19 | Board Of Supervisors Of Louisiana State Univeristy And Agricultural And Mechanical College | Extraction of collagen from calcified tissues |
US8518436B2 (en) * | 2005-05-16 | 2013-08-27 | Purdue Research Foundation | Engineered extracellular matrices |
CA2646074A1 (en) * | 2006-03-13 | 2007-09-20 | University Of South Florida | Self-assembling, collagen-based material for corneal replacement |
US20070269476A1 (en) | 2006-05-16 | 2007-11-22 | Voytik-Harbin Sherry L | Engineered extracellular matrices control stem cell behavior |
US20090175922A1 (en) * | 2006-05-16 | 2009-07-09 | Voytik-Harbin Sherry L | Three dimensional purified collagen matrices |
CN101091789B (en) * | 2006-06-19 | 2010-11-10 | 李勇 | Application of ocean collagen peptide in preparing medicine or foodstuff for adjusting immunity |
CA2656044C (en) | 2006-06-22 | 2015-10-20 | University Of South Florida | Collagen scaffolds, medical implants with same and methods of use |
WO2008033505A1 (en) * | 2006-09-13 | 2008-03-20 | University Of South Florida | Biocomposite for artificial tissue design |
AU2007297611B2 (en) * | 2006-09-21 | 2013-02-07 | Purdue Research Foundation | Collagen preparation and method of isolation |
US9867905B2 (en) * | 2007-12-10 | 2018-01-16 | Purdue Research Foundation | Collagen-based matrices with stem cells |
JP2009280508A (en) * | 2008-05-20 | 2009-12-03 | Hikari Ishii | Vascular aging inhibitor and anti-aging formulation |
KR101234328B1 (en) * | 2009-07-27 | 2013-02-18 | 라이프 퓨젼 엘엘씨 | Preparation of high purity collagen |
NZ599399A (en) * | 2009-10-07 | 2014-05-30 | Kerecis Ehf | A scaffold material for wound care and/or other tissue healing applications |
US9517196B2 (en) | 2012-06-06 | 2016-12-13 | Robell Research | Lip balm |
US20140066379A1 (en) * | 2012-08-30 | 2014-03-06 | Body Organ Biomedical Corp. | Recombinant vector, transgenic fish egg using the same and biomaterial using the same |
US9878071B2 (en) | 2013-10-16 | 2018-01-30 | Purdue Research Foundation | Collagen compositions and methods of use |
RU2567171C1 (en) | 2014-10-06 | 2015-11-10 | Общество с ограниченной ответственностью "Системы качества жизни" | Method for production of acetic dispersion of high molecular fish collagen |
WO2016172365A1 (en) | 2015-04-21 | 2016-10-27 | Purdue Research Foundation Office Of Technology Commercialization | Cell-collagen-silica composites and methods of making and using the same |
CA3061428A1 (en) | 2017-04-25 | 2018-11-01 | Purdue Research Foundation | 3-dimensional (3d) tissue-engineered muscle for tissue restoration |
CN107573415B (en) * | 2017-10-16 | 2021-09-14 | 海南华研胶原科技股份有限公司 | Extraction method and application of fish collagen |
KR102008944B1 (en) * | 2019-06-26 | 2019-08-08 | 김경림 | Collagen extraction apparatus capable of both pretreatment step and extraction step, and collagen extraction method using the same |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR582544A (en) * | 1923-06-07 | 1924-12-20 | New plastic material and process for obtaining it | |
FR582543A (en) * | 1923-06-07 | 1924-12-20 | New textile fiber and process for obtaining it | |
FR647030A (en) * | 1927-01-27 | 1928-11-19 | Improved process for obtaining high quality textile fibers using fish skins, such as and in particular chondropterygii-selachians | |
DE736769C (en) * | 1937-12-23 | 1944-03-16 | Studiengesellschaft Der Deutsc | Process for the production of plastic masses and molded bodies from them |
CH229190A (en) * | 1942-03-20 | 1943-10-15 | Studiengesellschaft Der Deutsc | Process for the production of artificial leather. |
FR2516927B1 (en) * | 1981-11-26 | 1986-05-23 | Merieux Fond | PROCESS FOR THE INDUSTRIAL PREPARATION OF COLLAGENIC MATERIALS FROM HUMAN PLACENTARY TISSUES, HUMAN COLLAGENIC MATERIALS OBTAINED, THEIR APPLICATION AS BIOMATERIALS |
DE3248188A1 (en) * | 1982-12-27 | 1984-06-28 | Behringwerke Ag, 3550 Marburg | METHOD FOR PRODUCING A COLLAGEN FLEECE |
JPS6283849A (en) * | 1985-10-04 | 1987-04-17 | Reiji Yoshinaka | Method of purifying collagen |
GB8812993D0 (en) * | 1988-06-01 | 1988-07-06 | Natural Resources Mfg Ltd | Improvements in/relating to production of protein products |
IL87344A (en) * | 1988-08-04 | 1992-03-29 | Univ Bar Ilan | Process for the production of gelatin from fish skins |
US5106949A (en) * | 1989-09-15 | 1992-04-21 | Organogenesis, Inc. | Collagen compositions and methods for preparation thereof |
-
1991
- 1991-07-04 FR FR9108400A patent/FR2678624A1/en active Granted
-
1992
- 1992-07-02 WO PCT/FR1992/000621 patent/WO1993001241A1/en active IP Right Grant
- 1992-07-02 CA CA002112805A patent/CA2112805C/en not_active Expired - Lifetime
- 1992-07-02 DE DE69221872T patent/DE69221872T2/en not_active Expired - Lifetime
- 1992-07-02 US US08/170,353 patent/US5420248A/en not_active Expired - Lifetime
- 1992-07-02 ES ES92915287T patent/ES2108759T3/en not_active Expired - Lifetime
- 1992-07-02 AT AT92915287T patent/ATE157386T1/en active
- 1992-07-02 JP JP5502013A patent/JP2722014B2/en not_active Expired - Lifetime
- 1992-07-02 EP EP92915287A patent/EP0592586B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1993001241A1 (en) | 1993-01-21 |
FR2678624A1 (en) | 1993-01-08 |
EP0592586A1 (en) | 1994-04-20 |
EP0592586B1 (en) | 1997-08-27 |
DE69221872T2 (en) | 1998-01-29 |
ATE157386T1 (en) | 1997-09-15 |
DE69221872D1 (en) | 1997-10-02 |
CA2112805C (en) | 2001-04-24 |
FR2678624B1 (en) | 1995-06-02 |
US5420248A (en) | 1995-05-30 |
JP2722014B2 (en) | 1998-03-04 |
JPH06511269A (en) | 1994-12-15 |
ES2108759T3 (en) | 1998-01-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |