CA2115045A1 - Composition for Curing Proliferative Skin Diseases - Google Patents

Composition for Curing Proliferative Skin Diseases

Info

Publication number
CA2115045A1
CA2115045A1 CA 2115045 CA2115045A CA2115045A1 CA 2115045 A1 CA2115045 A1 CA 2115045A1 CA 2115045 CA2115045 CA 2115045 CA 2115045 A CA2115045 A CA 2115045A CA 2115045 A1 CA2115045 A1 CA 2115045A1
Authority
CA
Canada
Prior art keywords
composition
proliferative skin
skin diseases
curing
curing proliferative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2115045
Other languages
French (fr)
Other versions
CA2115045C (en
Inventor
Makoto Kawashima
Kazuhiro Nagano
Kazuyoshi Hori
Hiroaki Ishikawa
Masataka Morishita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2115045A1 publication Critical patent/CA2115045A1/en
Application granted granted Critical
Publication of CA2115045C publication Critical patent/CA2115045C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals

Abstract

A composition for curing proliferative skin diseases having strong inhibitory action on the growth of epidermal keratinocyte cells as a psoriasis model, and providing an improvement in the curative effect for psoriasis patients. The medicament composition of the present invention is useful for treatment of proliferative skin disease.
Further it has higher safety, and can be administered for long term and perorally.
CA002115045A 1991-08-06 1992-08-03 Composition for curing proliferative skin diseases Expired - Lifetime CA2115045C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP21930191 1991-08-06
JP3-219301 1991-08-06
JP4212188A JPH06116151A (en) 1991-08-06 1992-07-16 Composition for treating proliferative dermatopathy
JP4-212188 1992-07-16

Publications (2)

Publication Number Publication Date
CA2115045A1 true CA2115045A1 (en) 1993-02-18
CA2115045C CA2115045C (en) 1997-01-21

Family

ID=26519057

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002115045A Expired - Lifetime CA2115045C (en) 1991-08-06 1992-08-03 Composition for curing proliferative skin diseases

Country Status (6)

Country Link
US (1) US5462929A (en)
EP (1) EP0661054A1 (en)
JP (1) JPH06116151A (en)
AU (1) AU2390492A (en)
CA (1) CA2115045C (en)
WO (1) WO1993002683A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2816837A1 (en) * 2000-11-17 2002-05-24 Oreal Use of amino sulfonic acid derivatives in cosmetic compositions to aid desquamation, counteract aging and stimulate epidermal renewal
EP1765336A4 (en) 2004-06-25 2010-03-10 Univ Johns Hopkins Angiogenesis inhibitors
US20080085912A1 (en) * 2006-10-06 2008-04-10 Unitech Pharmaceuticals, Inc. Isoxazole derivatives and methods of treating diseases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888843A (en) * 1973-06-12 1975-06-10 Toyo Jozo Kk 4-carbamoyl-1-' -d-ribofuranosylimidazolium-5-olate
JPS5652038B2 (en) * 1974-03-09 1981-12-09
JPS57156418A (en) * 1981-03-19 1982-09-27 Sumitomo Chem Co Ltd Carcinostatic
JPS59227817A (en) * 1983-06-07 1984-12-21 Toyo Jozo Co Ltd Long-acting bredinin preparation for oral administration
US4788061A (en) * 1985-07-05 1988-11-29 Shore Ronald N Extended occlusive treatment of skin disorders
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
JPH0649650B2 (en) * 1990-05-17 1994-06-29 旭化成工業株式会社 Use of 4-carbamoyl-1-β-D-ribofuranosyl-imidazolium-5-oleate as an active ingredient
JPH0426626A (en) * 1990-05-22 1992-01-29 Asahi Chem Ind Co Ltd Preventive or curing drug containing 4-carbamoyl-1-beta-d-ribofuranosyl-imidazolium-5-olate as active ingredient
US5204329A (en) * 1990-06-11 1993-04-20 Du Pont Merck Pharmaceutical Company Treatment of organ transplantation rejection
US5135934A (en) * 1990-07-06 1992-08-04 Du Pont Merck Pharmaceutical Company 3-phenyl-5,6-dihydrobenz(c) acridine-7-carboxylic acids and related compounds as immunosuppressive agents
US5283257A (en) * 1992-07-10 1994-02-01 The Board Of Trustees Of The Leland Stanford Junior University Method of treating hyperproliferative vascular disease

Also Published As

Publication number Publication date
EP0661054A4 (en) 1994-05-17
AU2390492A (en) 1993-03-02
EP0661054A1 (en) 1995-07-05
CA2115045C (en) 1997-01-21
US5462929A (en) 1995-10-31
JPH06116151A (en) 1994-04-26
WO1993002683A1 (en) 1993-02-18

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Legal Events

Date Code Title Description
EEER Examination request
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