CA2124050A1 - Stent-loading mechanism - Google Patents
Stent-loading mechanismInfo
- Publication number
- CA2124050A1 CA2124050A1 CA002124050A CA2124050A CA2124050A1 CA 2124050 A1 CA2124050 A1 CA 2124050A1 CA 002124050 A CA002124050 A CA 002124050A CA 2124050 A CA2124050 A CA 2124050A CA 2124050 A1 CA2124050 A1 CA 2124050A1
- Authority
- CA
- Canada
- Prior art keywords
- stent
- catheter
- loading device
- onto
- plates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/958—Inflatable balloons for placing stents or stent-grafts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C63/00—Lining or sheathing, i.e. applying preformed layers or sheathings of plastics; Apparatus therefor
- B29C63/18—Lining or sheathing, i.e. applying preformed layers or sheathings of plastics; Apparatus therefor using tubular layers or sheathings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
- B29C65/56—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using mechanical means or mechanical connections, e.g. form-fits
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/05—Particular design of joint configurations
- B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
- B29C66/11—Joint cross-sections comprising a single joint-segment, i.e. one of the parts to be joined comprising a single joint-segment in the joint cross-section
- B29C66/112—Single lapped joints
- B29C66/1122—Single lap to lap joints, i.e. overlap joints
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/05—Particular design of joint configurations
- B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
- B29C66/12—Joint cross-sections combining only two joint-segments; Tongue and groove joints; Tenon and mortise joints; Stepped joint cross-sections
- B29C66/124—Tongue and groove joints
- B29C66/1244—Tongue and groove joints characterised by the male part, i.e. the part comprising the tongue
- B29C66/12443—Tongue and groove joints characterised by the male part, i.e. the part comprising the tongue having the tongue substantially in the middle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
- B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
- B29C66/53—Joining single elements to tubular articles, hollow articles or bars
- B29C66/534—Joining single elements to open ends of tubular or hollow articles or to the ends of bars
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
- B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
- B29C66/53—Joining single elements to tubular articles, hollow articles or bars
- B29C66/534—Joining single elements to open ends of tubular or hollow articles or to the ends of bars
- B29C66/5344—Joining single elements to open ends of tubular or hollow articles or to the ends of bars said single elements being substantially annular, i.e. of finite length, e.g. joining flanges to tube ends
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/80—General aspects of machine operations or constructions and parts thereof
- B29C66/83—General aspects of machine operations or constructions and parts thereof characterised by the movement of the joining or pressing tools
- B29C66/832—Reciprocating joining or pressing tools
- B29C66/8322—Joining or pressing tools reciprocating along one axis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/9522—Means for mounting a stent or stent-graft onto or into a placement instrument
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
- B29C66/71—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the composition of the plastics material of the parts to be joined
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
- B29C66/71—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the composition of the plastics material of the parts to be joined
- B29C66/712—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the composition of the plastics material of the parts to be joined the composition of one of the parts to be joined being different from the composition of the other part
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
- B29L2031/7542—Catheters
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49764—Method of mechanical manufacture with testing or indicating
- Y10T29/49771—Quantitative measuring or gauging
- Y10T29/49776—Pressure, force, or weight determining
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49826—Assembling or joining
- Y10T29/49908—Joining by deforming
- Y10T29/49925—Inward deformation of aperture or hollow body wall
- Y10T29/49927—Hollow body is axially joined cup or tube
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/53—Means to assemble or disassemble
- Y10T29/53657—Means to assemble or disassemble to apply or remove a resilient article [e.g., tube, sleeve, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/53—Means to assemble or disassemble
- Y10T29/53987—Tube, sleeve or ferrule
Abstract
ABSTRACT
A stent-loading mechanism for automatically loading a stent onto a balloon delivery catheter of the kind used in typical percutaneous transluminal coronary angioplasty (PTCA) procedures. The device comprises a tubular member housing an elongated elastic bladder that surrounds the stent to be loaded. The distal end of the balloon catheter assembly and the stent are placed inside the tubular member and pressurized fluid is applied to the bladder to compress and affix the stent onto the out-side of the catheter assembly.
Another embodiment of the stent-loading device comprises a series of plates having substantially flat and parallel surfaces that move in a rectilinear fashion with respect to each other. A stent-carrying catheter can be disposed between these surfaces to affix the stent onto the outside of the catheter by providing relative motion between the plates. The plates may have multiple degrees of freedom and force-indicating transducers to measure and indicate the force applied to the catheter during affixation of the stent.
A stent-loading mechanism for automatically loading a stent onto a balloon delivery catheter of the kind used in typical percutaneous transluminal coronary angioplasty (PTCA) procedures. The device comprises a tubular member housing an elongated elastic bladder that surrounds the stent to be loaded. The distal end of the balloon catheter assembly and the stent are placed inside the tubular member and pressurized fluid is applied to the bladder to compress and affix the stent onto the out-side of the catheter assembly.
Another embodiment of the stent-loading device comprises a series of plates having substantially flat and parallel surfaces that move in a rectilinear fashion with respect to each other. A stent-carrying catheter can be disposed between these surfaces to affix the stent onto the outside of the catheter by providing relative motion between the plates. The plates may have multiple degrees of freedom and force-indicating transducers to measure and indicate the force applied to the catheter during affixation of the stent.
Description
2 1 2 ~
~`
BACKG~OUND OF ~HE INV~NTION
- Field of the Invention ,3' This invention relates to a stent-loading l device that will automatically load a stent onto the distal end of a balloon dilatation catheter assembly, for example, of the kind used in typical percutaneous transluminal coronary angioplasty (PTCA) procedures.
l In typical PTCA procedures, a guiding catheter i~ is percutaneou~ly introduced into the cardiovascular s 10 system of a patient through the brachial or femoral arteries and advanced through the vasculature until the distal end of the guiding catheter is in the ostium. A
guidewire and a dilatation catheter having a balloon on the distal end are introduced through the guiding catheter with the guidewire sliding within the dilatation catheter. The guidewire is first advanced out of the guiding catheter into the patient's coronary vasculature and the dilatation catheter is advanced over the pre-viou~ly advanced guidewire until the dilatation balloon is properly positioned across the lesion. once in position across the lesion, a flexible, expandable, preformed balloon is inflated to a predetermined size with a radiopaque liquid at relatively high pressures to radially compress the atherosclerotic plaque of the lesion against the inside of the artery wall and thereby dilate the lumen of the artery. The balloon is then deflated to a small profile, so that the dilatation catheter can be withdrawn from the patient's vasculature and blood flow resumed through the dilated artery. As should be appreciated by those skilled in the art, while the procedure just described is typical, it is not the only method used in angioplasty.
2 1 ~
. `
!3 -2-!''i In angioplasty procedures of the kind refer-enced above, there may be restenosis of the artery, which may require another angioplasty procedure, a surgical bypass operation, or some method of repairing or strengthening the area. To reduce the chance of ~ restenosis and strengthen the area, a physician can Q implant an intravascular prosthesis for maintaining j vascular patency, typically designated by the term called , a stent, inside the artery at the lesion. The stent ; 10 typically is expanded to a larger diameter, often by the i balloon portion of the catheter. The stent may be of the self-expanding type.
SUMMARY_OF THE INVENTION
This invention is directed to a vascular prosthesis loading device, which automatically loads a stent onto the distal end of a catheter assembly with a minimum of human handling, to better and more consistently secure the stent onto the catheter before the stent is delivered through the patient's vasculature.
The present invention attempts to solve several problems associated with placing stents onto balloon catheters. In procedures where the stent is placed over the balloon portion of the catheter, one must crimp the stent onto the balloon portion, to prevent the stent from sliding off the catheter when the catheter is advanced in a patient's vasculature. In the past, this crimping was often done by hand, which was found to be unsatisfactory due to uneven and being applied, resulting in non-uniform crimps. In addition, it is difficult to judge when a uniform and reliable crimp has been accomplished.
Furthermore, the more the stent is handled, the greater the chance of human error in crimping the stent properly.
Though some tools, similar to ordinary pliers, have been ~ ~2~5~
:", used to apply the stent, these tools have not been entirely adequate in achieving a sati~factory, uniformly radial crimp.
~, In one embodiment of the present invention, the stent-loading device includes a tubular member housing a bladder. The tubular member and bladder are designed to hold a stent that is to be loaded onto a balloon catheter assembly. Upon placement of the stent over the balloon portion of the catheter, a valve in the loading device is activated to inflate the bladder. The bladder compresses 3 the stent radially inwardly to a reduced diameter onto the balloon portion of the catheter, to achieve a snug fit. In this way the stent can be affixed onto the ~I dis~al end of a balloon catheter with a minimum of human handling.
j In other embodiments of the present invention, i the stent-loading device is made of sliding plates having I flat surfaces that allow a stent carrying catheter to be ¦ received in between them. The surfaces are moved 1 20 relative to one another to apply force uniformly to the outside of the stent disposed on the catheter, allowing the ~tent to be crimped onto the outside of the catheter.
These and other advantages of the invention will become more apparent from the following detailed description thereof when taken in conjunction with the accompanying drawings.
BRIEF DESCRIPTION OF THE DRAWINGS --FIG. l is a cross-sectional schematic of one embodiment of the stent-loading device depicting the bladder and chamber for receiving the stent.
FIG. 2 is a cut-away perspective view of the stent-loading device of FIG. 1.
,. .. -~ .:~ .
' '~1 2 1 2 ~
J, FIG. 3 is a cut-away perspective view of the stent-loading device of FIG. 1, showing a balloon catheter assembly about to be inserted into the device, and a stent received by the device.
FIG. 4 is a cut-away perspective view of the stent-loading device of FIG. 1, when it is operated to ~ load a stent onto a balloon catheter assembly that has 3 been placed inside the device.
`Y7 FIG. 5 is a perspective view of a second embodiment of the present invention depicting sliding plates with a stent be placed between the plates.
FIG. 6 is a perspective view of the back of one 7 of the blocks of the embodiment shown in FIG. 5.
FIG. 7 is a side view of the second embodiment of the present invention.
FIG. 8 is a perspective view of a third embodi- -ment of the present invention.
FIG. g shows the slider plate of the embodiment of FIG. 8.
FIG. 10 shows the spring-loaded plate of the embodiment of FIG. 8. - -FIG. 11 shows the housing of the embodiment of FIG. 8.
. ~ .
DETAILED DESCRIPTION OF THE INVENTION
As shown by Figs. 1-4, the first embodiment of the stent-loading device 1 includes an elongated tubular member 5, having an open end 10 and a sealed-off end 15.
The tubular member houses an elastic bladder 20, which extends longitudinally along the inside of the tubular member. The bladder is secured to the tubular member by fastener ring 25, which clamps the bladder onto the tubular member. The bladder extends out of the open end s ~
of the tubular member and is ~olded over outside end 30 of the tubular member.
The tubular member can be made of a stainless steel or polytetrafluoroethylene-lined hypotube.
Polytetrafluoroethylene is manufactured under the trademark TeflonTM. The bladder can be made of any ,; flexible, elastic material, such as polyethylene ;~, material.
The bladder is sealed at its end 35. The bladder end may be sealed by heat sealing, by an ¦ adhesive, by tying, or by clamping with a hemostat, depending on the bladder material used. As shown in the figures, the bladder seals from atmosphere an annular fluid chamber 40 in the tubular member. Chamber 40 c~n be placed under pressure by a pressurized fluid source 50, which is in fluid communication with the chamber via inflation port 55 fitted with an inflation valve 60. In the preferred embodiment, an adaptor with a male-threaded Luer fitting is used as an inflation port. A syringe, an inflation/deflation device commonly referred to as an "indeflator," a compressed fluid source or another pressurizing means 50 is attached to the inflation port.
Operation of the stent-loading device of ~igs.
1-4 now will be described. When it is desired to load a stent 65 onto a balloon catheter assembly 70, a stent is inserted inside the open end 10 of the tubular member 5.
The stent is confined inside the tubular member by the inner walls of the bladder, with the bladder being in a ~ non-compressed state. The collapsed balloon port~on 85, adjacent distal end 90 of the ballvon catheter 95, is inserted inside the stent so the stent overlies the balloon portion. At this point, there is no pressure inside the sealed fluid chamber 40.
To load and attach the stent onto the balloon portion o~ the catheter assembly, the catheter is brought `: l into operating engagement with the stent-loading device.
The catheter has been checked and prepped be~ore this time, and the profile of the balloon portion 85 has been reduced to its minimum. As illustrated in Fig. 3, the catheter is inserted with its distal end first into open ~3 end 10 of the tubular member. To achieve insertion, the ~; balloon catheter assembly may be held stationary while i~ the stent delivery device is moved relative to the catheter. The catheter distal end is inserted far enough into the tubular member so the stent is positioned over the desired position on the catheter. At this point, the stent is not fixed onto the balloon catheter assembly, because the stent has not been compressed.
The stent is attached onto the balloon 85 of catheter 95 by first pressurizing chamber 40. As chamber 40 is pres~urized, tubular member 5 becomes pressurized, and the pressure is transferred to the bladder, which causes it to compress radially inwardly the stent onto the balloon portion of the catheter, at a substantially uniform rate. The inflation of the chamber is depicted by dotted shading in Fig. 4. Pressurized fluid may be introduced into chamber 40 through inflation port 55 controlled by a suitable valve 60 by way of a compressed fluid source 50, as shown in Fig. 1. The fluid may also be introduced by way of a syringe or plunger arrangement, such as an indeflator. Other suitable pressurizing gas or fluid sources are contemplated, as should be appreci~
ated by sne skilled in the art.
After a predetermined pressure hasl been achieved and the stent has been affixed to the outside of the balloon portion of the balloon catheter assembly, the bladder 10 is decompressed by releasing the pressurized fluid from inside the chamber through valve 60. Tubular member 5 is then withdrawn from over the catheter assembly. The delivery catheter, now loaded with a , :,:
,, .~
2 1 2 ~
: j -~`
:~
stent, is ready to be inserted into the body of a patient for deployment.
Furthermore, the stent-loading device of Figs.
1-4 may be used to compress and affix a stent that has been first manually placed over a balloon catheter.
Turning attention now to Figs. 5-7, there is shown a second embodiment of the present invention. In Fig. 5 there is shown an isometric perspective view of the device. The device comprising a pair of plates, a lower support plate 100 and an upper support plate 120, that form flat surfaces or faces 125, 130, in between which a stent-carrying catheter may be placed, as indicated by arrow 135. Uniform pressure may be applied to crimp the stent onto the catheter, by reciprocating surfaces 125, 130 relative to one another. Plates 100, 120 may be made of aluminum, and may be hollow. Thin rubber or elastomeric surfaces are laminated onto faces 125, 130 to better grip the stent and catheter and prevent them from sliding. The upper face 130 has a thicker rubber or elastomeric surface, about 3/4" thick, and the lower face 125 has a thinner rubber surface, about l/4" thick.
Lower support plate 100 is fixed to base 140 while upper support plate 120 is movable, being affixed to flat rectangular surface 145 which in turn is affixed to channel-shaped block 150. Channel-shaped block 150 translates in two directions. Channel-shaped block 150 has a horizontally-extending channel or groove 155 ` ! extending along its length through which it slidably receives a guide-bearing surface 160. Guide-bearing surface 160 in turn has a vertically-extending channel or groove 165 on its back side, as can be seen in Fig. 6, which receives a rail 170. Rail 170 is fixed to upright channel-shaped support 175. Upright channel support 175 in turn has a groove 180 that can slidably receive a :~a, ., . i ; !
2124~0 . - ~
fixed rail 185. Fixed rail 185 i8 immobile, fixed to a vertical post 190, which is attached to base 140.
Spring arms 172, 174 provide bias along the axial direction (the direction of arrow 135) to keep block 150, guide-bearing surface 160, and rail 170 together. In addition spring arms 172, 174 provide a vertical bias to keep faces 125, 130 separated.
As can be appreciated from an examination of Figs. 5-7, guide bearing surface 160 allows two degrees of freedom for the translation of plate 120, that is, allowing for movement along vertical and horizontal directions. Preferably these directions are i; substantially orthogonal directions, that is, at right angles to one another, as shown by the unmarked double headed arrows in Fig. 5.
Furthermore, the use of several redundant sliding surfaces, such as guide-bearing surface 160 in ¦ conjunction with channel-shaped support 175, both sliding along rails in the vertical direction, allows for reduced friction in the event there is excessive friction along one sliding surface. Multiple sliding surfaces may be employed for horizontal travel as well.
Furthermore, upper block 150 is spring biased upwards from lower support plate lO0 by spring arms 172, 174. The arms provide for the upper block 150 to be spaced from lower support plate 100, and to give a resilient feel to an operator pressing down on upper block 150. The spring-biased arms may have spring tensioning means to adjust the spring tension in the arms, as well as dampening means for providing dampening.
In addition, a force transducer 195, such as a strain gage or piezoelectric crystal, may be disposed in plate 100 and/or plate 120, or in faces 125, 130, to measure the contact force applied to the stent disposed between the plates. Force transducer 195 may have a ,I ` ~` 21% ~
.
~, 9 .~ .
display 200, giving visual and/or audio output, to pro-vide feedback to the operator and to indicate when either sufficient and/or excessive force has been imparted to the catheter.
~l 5 Operation of the Figs. 5-7 embodiment is achieved by placing a catheter that has a stent disposed ;~ about its stent-receiving portion, which in a balloon catheter would be the balloon portion of the catheter, in between the space formed between the substantially flat surfaces of faces 125, 130. The operator then gently l reciprocates plate 120 to move face 130, which contacts 3 the stent-receiving catheter, with respect to face 125, which is fixed and aIso contacts the catheter, to apply a slight downward force and evenly crimp the stent onto the catheter. The gentle reciprocating motion of the two substantially flat rubberized faces 125, 130, together with the downward application of force, insures an even application of force to the outside of the stent and ¦ achieves a uniform crimping of the stent onto the catheter.
Turning attention now to Figs. 8-11, there is shown another embodiment of the present invention employing sliding plates that operate in principle according to the embodiment of Fig. 5. A horizontally-sliding plate 215 moves relative to a vertically-sliding plate 220. Horizontally-sliding plate 215 slides along grooves 225 in housing 230, via rails 235. Vertically-sliding plate 220 is retained in U-shaped housing 230 by a ridge 240, but is free to travel upwards along the inside edge 245 of housing 230. Vertically-sliding plate 22~ has a push plate 250 connected to it by springs 255.
By pushing on push plate 250 the plates 215 and 220 can be resiliently biased together. In this way a user may apply pressure to the underside of vertically-sliding plate 220 by pushing on push plate 250. As can be :, , ~! `
2~v~
;1 ' ,1 " --1 0--i appreciated from Figs. 8-11, horiæontally-sliding plate ;1 215 and vertically-sliding plate 220 move along ;; substantially orthogonal directions.
In the operation of the device, a stent-carrying catheter 260 is placed in between plates 220 and 215, with catheter 260 entering through slot 265, and i facing transverse to the direction of movement of `~ horizontally-sliding plate 215. Thereinafter, horizontally-sliding plate 215 is moved relative to vertically-sliding plate 220, to compress the stent about the catheter. As can be seen from the drawings, horizontally-sliding plate 215 is constrained by groovss 225 to move along a single direction relative to ,l vertically-sliding plate 220.
As is the case with the embodiment shown in Figs. 5-7, a force measuring transducer ~nd suitable output may be placed in either or both of plates 215 and 220 to measure the force imparted to the stent-carrying catheter and to indicate the results.
The embodiment of Figs. 8-11 is sized to fit into the palm of a user. The horizontally-sliding plate ¦ 215 can be reciprocated with a thumb while housing 230 is held in the palm of the user, and the user's fingers can ¦ apply pressure to push plate 250 affixed to the underside of vertically sliding plate 220. Springs 255 oppose the force of the user's fingers. In this way feedback can be experienced by the user.
While in the preferred embodiment the stent described is intended to be an intraluminal vascular prosthesis for use within a blood vessel, and the balloon delivery catheter is of the kind used in therapeutic coronary angioplasty, it will be appreciated by those skilled in the art that modifications may be made to the present invention to allow the present invention to be used to load any type of prosthesis. The pr esent C~12~
invention is not limited to stents that are deployed in a patient's vasculature, but has wide applications to . loading any type of graft, prosthesis, liner or similar structure. Furthermore, the stent may be delivered not only into coronary arteries but into any body lumen.
~ Other modifications can be made to the present invention fl by those skilled in the art without departing from the scope thereof.
''.'., : ~.
~`
BACKG~OUND OF ~HE INV~NTION
- Field of the Invention ,3' This invention relates to a stent-loading l device that will automatically load a stent onto the distal end of a balloon dilatation catheter assembly, for example, of the kind used in typical percutaneous transluminal coronary angioplasty (PTCA) procedures.
l In typical PTCA procedures, a guiding catheter i~ is percutaneou~ly introduced into the cardiovascular s 10 system of a patient through the brachial or femoral arteries and advanced through the vasculature until the distal end of the guiding catheter is in the ostium. A
guidewire and a dilatation catheter having a balloon on the distal end are introduced through the guiding catheter with the guidewire sliding within the dilatation catheter. The guidewire is first advanced out of the guiding catheter into the patient's coronary vasculature and the dilatation catheter is advanced over the pre-viou~ly advanced guidewire until the dilatation balloon is properly positioned across the lesion. once in position across the lesion, a flexible, expandable, preformed balloon is inflated to a predetermined size with a radiopaque liquid at relatively high pressures to radially compress the atherosclerotic plaque of the lesion against the inside of the artery wall and thereby dilate the lumen of the artery. The balloon is then deflated to a small profile, so that the dilatation catheter can be withdrawn from the patient's vasculature and blood flow resumed through the dilated artery. As should be appreciated by those skilled in the art, while the procedure just described is typical, it is not the only method used in angioplasty.
2 1 ~
. `
!3 -2-!''i In angioplasty procedures of the kind refer-enced above, there may be restenosis of the artery, which may require another angioplasty procedure, a surgical bypass operation, or some method of repairing or strengthening the area. To reduce the chance of ~ restenosis and strengthen the area, a physician can Q implant an intravascular prosthesis for maintaining j vascular patency, typically designated by the term called , a stent, inside the artery at the lesion. The stent ; 10 typically is expanded to a larger diameter, often by the i balloon portion of the catheter. The stent may be of the self-expanding type.
SUMMARY_OF THE INVENTION
This invention is directed to a vascular prosthesis loading device, which automatically loads a stent onto the distal end of a catheter assembly with a minimum of human handling, to better and more consistently secure the stent onto the catheter before the stent is delivered through the patient's vasculature.
The present invention attempts to solve several problems associated with placing stents onto balloon catheters. In procedures where the stent is placed over the balloon portion of the catheter, one must crimp the stent onto the balloon portion, to prevent the stent from sliding off the catheter when the catheter is advanced in a patient's vasculature. In the past, this crimping was often done by hand, which was found to be unsatisfactory due to uneven and being applied, resulting in non-uniform crimps. In addition, it is difficult to judge when a uniform and reliable crimp has been accomplished.
Furthermore, the more the stent is handled, the greater the chance of human error in crimping the stent properly.
Though some tools, similar to ordinary pliers, have been ~ ~2~5~
:", used to apply the stent, these tools have not been entirely adequate in achieving a sati~factory, uniformly radial crimp.
~, In one embodiment of the present invention, the stent-loading device includes a tubular member housing a bladder. The tubular member and bladder are designed to hold a stent that is to be loaded onto a balloon catheter assembly. Upon placement of the stent over the balloon portion of the catheter, a valve in the loading device is activated to inflate the bladder. The bladder compresses 3 the stent radially inwardly to a reduced diameter onto the balloon portion of the catheter, to achieve a snug fit. In this way the stent can be affixed onto the ~I dis~al end of a balloon catheter with a minimum of human handling.
j In other embodiments of the present invention, i the stent-loading device is made of sliding plates having I flat surfaces that allow a stent carrying catheter to be ¦ received in between them. The surfaces are moved 1 20 relative to one another to apply force uniformly to the outside of the stent disposed on the catheter, allowing the ~tent to be crimped onto the outside of the catheter.
These and other advantages of the invention will become more apparent from the following detailed description thereof when taken in conjunction with the accompanying drawings.
BRIEF DESCRIPTION OF THE DRAWINGS --FIG. l is a cross-sectional schematic of one embodiment of the stent-loading device depicting the bladder and chamber for receiving the stent.
FIG. 2 is a cut-away perspective view of the stent-loading device of FIG. 1.
,. .. -~ .:~ .
' '~1 2 1 2 ~
J, FIG. 3 is a cut-away perspective view of the stent-loading device of FIG. 1, showing a balloon catheter assembly about to be inserted into the device, and a stent received by the device.
FIG. 4 is a cut-away perspective view of the stent-loading device of FIG. 1, when it is operated to ~ load a stent onto a balloon catheter assembly that has 3 been placed inside the device.
`Y7 FIG. 5 is a perspective view of a second embodiment of the present invention depicting sliding plates with a stent be placed between the plates.
FIG. 6 is a perspective view of the back of one 7 of the blocks of the embodiment shown in FIG. 5.
FIG. 7 is a side view of the second embodiment of the present invention.
FIG. 8 is a perspective view of a third embodi- -ment of the present invention.
FIG. g shows the slider plate of the embodiment of FIG. 8.
FIG. 10 shows the spring-loaded plate of the embodiment of FIG. 8. - -FIG. 11 shows the housing of the embodiment of FIG. 8.
. ~ .
DETAILED DESCRIPTION OF THE INVENTION
As shown by Figs. 1-4, the first embodiment of the stent-loading device 1 includes an elongated tubular member 5, having an open end 10 and a sealed-off end 15.
The tubular member houses an elastic bladder 20, which extends longitudinally along the inside of the tubular member. The bladder is secured to the tubular member by fastener ring 25, which clamps the bladder onto the tubular member. The bladder extends out of the open end s ~
of the tubular member and is ~olded over outside end 30 of the tubular member.
The tubular member can be made of a stainless steel or polytetrafluoroethylene-lined hypotube.
Polytetrafluoroethylene is manufactured under the trademark TeflonTM. The bladder can be made of any ,; flexible, elastic material, such as polyethylene ;~, material.
The bladder is sealed at its end 35. The bladder end may be sealed by heat sealing, by an ¦ adhesive, by tying, or by clamping with a hemostat, depending on the bladder material used. As shown in the figures, the bladder seals from atmosphere an annular fluid chamber 40 in the tubular member. Chamber 40 c~n be placed under pressure by a pressurized fluid source 50, which is in fluid communication with the chamber via inflation port 55 fitted with an inflation valve 60. In the preferred embodiment, an adaptor with a male-threaded Luer fitting is used as an inflation port. A syringe, an inflation/deflation device commonly referred to as an "indeflator," a compressed fluid source or another pressurizing means 50 is attached to the inflation port.
Operation of the stent-loading device of ~igs.
1-4 now will be described. When it is desired to load a stent 65 onto a balloon catheter assembly 70, a stent is inserted inside the open end 10 of the tubular member 5.
The stent is confined inside the tubular member by the inner walls of the bladder, with the bladder being in a ~ non-compressed state. The collapsed balloon port~on 85, adjacent distal end 90 of the ballvon catheter 95, is inserted inside the stent so the stent overlies the balloon portion. At this point, there is no pressure inside the sealed fluid chamber 40.
To load and attach the stent onto the balloon portion o~ the catheter assembly, the catheter is brought `: l into operating engagement with the stent-loading device.
The catheter has been checked and prepped be~ore this time, and the profile of the balloon portion 85 has been reduced to its minimum. As illustrated in Fig. 3, the catheter is inserted with its distal end first into open ~3 end 10 of the tubular member. To achieve insertion, the ~; balloon catheter assembly may be held stationary while i~ the stent delivery device is moved relative to the catheter. The catheter distal end is inserted far enough into the tubular member so the stent is positioned over the desired position on the catheter. At this point, the stent is not fixed onto the balloon catheter assembly, because the stent has not been compressed.
The stent is attached onto the balloon 85 of catheter 95 by first pressurizing chamber 40. As chamber 40 is pres~urized, tubular member 5 becomes pressurized, and the pressure is transferred to the bladder, which causes it to compress radially inwardly the stent onto the balloon portion of the catheter, at a substantially uniform rate. The inflation of the chamber is depicted by dotted shading in Fig. 4. Pressurized fluid may be introduced into chamber 40 through inflation port 55 controlled by a suitable valve 60 by way of a compressed fluid source 50, as shown in Fig. 1. The fluid may also be introduced by way of a syringe or plunger arrangement, such as an indeflator. Other suitable pressurizing gas or fluid sources are contemplated, as should be appreci~
ated by sne skilled in the art.
After a predetermined pressure hasl been achieved and the stent has been affixed to the outside of the balloon portion of the balloon catheter assembly, the bladder 10 is decompressed by releasing the pressurized fluid from inside the chamber through valve 60. Tubular member 5 is then withdrawn from over the catheter assembly. The delivery catheter, now loaded with a , :,:
,, .~
2 1 2 ~
: j -~`
:~
stent, is ready to be inserted into the body of a patient for deployment.
Furthermore, the stent-loading device of Figs.
1-4 may be used to compress and affix a stent that has been first manually placed over a balloon catheter.
Turning attention now to Figs. 5-7, there is shown a second embodiment of the present invention. In Fig. 5 there is shown an isometric perspective view of the device. The device comprising a pair of plates, a lower support plate 100 and an upper support plate 120, that form flat surfaces or faces 125, 130, in between which a stent-carrying catheter may be placed, as indicated by arrow 135. Uniform pressure may be applied to crimp the stent onto the catheter, by reciprocating surfaces 125, 130 relative to one another. Plates 100, 120 may be made of aluminum, and may be hollow. Thin rubber or elastomeric surfaces are laminated onto faces 125, 130 to better grip the stent and catheter and prevent them from sliding. The upper face 130 has a thicker rubber or elastomeric surface, about 3/4" thick, and the lower face 125 has a thinner rubber surface, about l/4" thick.
Lower support plate 100 is fixed to base 140 while upper support plate 120 is movable, being affixed to flat rectangular surface 145 which in turn is affixed to channel-shaped block 150. Channel-shaped block 150 translates in two directions. Channel-shaped block 150 has a horizontally-extending channel or groove 155 ` ! extending along its length through which it slidably receives a guide-bearing surface 160. Guide-bearing surface 160 in turn has a vertically-extending channel or groove 165 on its back side, as can be seen in Fig. 6, which receives a rail 170. Rail 170 is fixed to upright channel-shaped support 175. Upright channel support 175 in turn has a groove 180 that can slidably receive a :~a, ., . i ; !
2124~0 . - ~
fixed rail 185. Fixed rail 185 i8 immobile, fixed to a vertical post 190, which is attached to base 140.
Spring arms 172, 174 provide bias along the axial direction (the direction of arrow 135) to keep block 150, guide-bearing surface 160, and rail 170 together. In addition spring arms 172, 174 provide a vertical bias to keep faces 125, 130 separated.
As can be appreciated from an examination of Figs. 5-7, guide bearing surface 160 allows two degrees of freedom for the translation of plate 120, that is, allowing for movement along vertical and horizontal directions. Preferably these directions are i; substantially orthogonal directions, that is, at right angles to one another, as shown by the unmarked double headed arrows in Fig. 5.
Furthermore, the use of several redundant sliding surfaces, such as guide-bearing surface 160 in ¦ conjunction with channel-shaped support 175, both sliding along rails in the vertical direction, allows for reduced friction in the event there is excessive friction along one sliding surface. Multiple sliding surfaces may be employed for horizontal travel as well.
Furthermore, upper block 150 is spring biased upwards from lower support plate lO0 by spring arms 172, 174. The arms provide for the upper block 150 to be spaced from lower support plate 100, and to give a resilient feel to an operator pressing down on upper block 150. The spring-biased arms may have spring tensioning means to adjust the spring tension in the arms, as well as dampening means for providing dampening.
In addition, a force transducer 195, such as a strain gage or piezoelectric crystal, may be disposed in plate 100 and/or plate 120, or in faces 125, 130, to measure the contact force applied to the stent disposed between the plates. Force transducer 195 may have a ,I ` ~` 21% ~
.
~, 9 .~ .
display 200, giving visual and/or audio output, to pro-vide feedback to the operator and to indicate when either sufficient and/or excessive force has been imparted to the catheter.
~l 5 Operation of the Figs. 5-7 embodiment is achieved by placing a catheter that has a stent disposed ;~ about its stent-receiving portion, which in a balloon catheter would be the balloon portion of the catheter, in between the space formed between the substantially flat surfaces of faces 125, 130. The operator then gently l reciprocates plate 120 to move face 130, which contacts 3 the stent-receiving catheter, with respect to face 125, which is fixed and aIso contacts the catheter, to apply a slight downward force and evenly crimp the stent onto the catheter. The gentle reciprocating motion of the two substantially flat rubberized faces 125, 130, together with the downward application of force, insures an even application of force to the outside of the stent and ¦ achieves a uniform crimping of the stent onto the catheter.
Turning attention now to Figs. 8-11, there is shown another embodiment of the present invention employing sliding plates that operate in principle according to the embodiment of Fig. 5. A horizontally-sliding plate 215 moves relative to a vertically-sliding plate 220. Horizontally-sliding plate 215 slides along grooves 225 in housing 230, via rails 235. Vertically-sliding plate 220 is retained in U-shaped housing 230 by a ridge 240, but is free to travel upwards along the inside edge 245 of housing 230. Vertically-sliding plate 22~ has a push plate 250 connected to it by springs 255.
By pushing on push plate 250 the plates 215 and 220 can be resiliently biased together. In this way a user may apply pressure to the underside of vertically-sliding plate 220 by pushing on push plate 250. As can be :, , ~! `
2~v~
;1 ' ,1 " --1 0--i appreciated from Figs. 8-11, horiæontally-sliding plate ;1 215 and vertically-sliding plate 220 move along ;; substantially orthogonal directions.
In the operation of the device, a stent-carrying catheter 260 is placed in between plates 220 and 215, with catheter 260 entering through slot 265, and i facing transverse to the direction of movement of `~ horizontally-sliding plate 215. Thereinafter, horizontally-sliding plate 215 is moved relative to vertically-sliding plate 220, to compress the stent about the catheter. As can be seen from the drawings, horizontally-sliding plate 215 is constrained by groovss 225 to move along a single direction relative to ,l vertically-sliding plate 220.
As is the case with the embodiment shown in Figs. 5-7, a force measuring transducer ~nd suitable output may be placed in either or both of plates 215 and 220 to measure the force imparted to the stent-carrying catheter and to indicate the results.
The embodiment of Figs. 8-11 is sized to fit into the palm of a user. The horizontally-sliding plate ¦ 215 can be reciprocated with a thumb while housing 230 is held in the palm of the user, and the user's fingers can ¦ apply pressure to push plate 250 affixed to the underside of vertically sliding plate 220. Springs 255 oppose the force of the user's fingers. In this way feedback can be experienced by the user.
While in the preferred embodiment the stent described is intended to be an intraluminal vascular prosthesis for use within a blood vessel, and the balloon delivery catheter is of the kind used in therapeutic coronary angioplasty, it will be appreciated by those skilled in the art that modifications may be made to the present invention to allow the present invention to be used to load any type of prosthesis. The pr esent C~12~
invention is not limited to stents that are deployed in a patient's vasculature, but has wide applications to . loading any type of graft, prosthesis, liner or similar structure. Furthermore, the stent may be delivered not only into coronary arteries but into any body lumen.
~ Other modifications can be made to the present invention fl by those skilled in the art without departing from the scope thereof.
''.'., : ~.
Claims (21)
1. A stent-loading device for loading a stent onto a catheter comprising:
a first substantially flat surface and a second substantially flat surface, said second flat surface spaced from said first flat surface a distance sufficient to allow a catheter having a stent deployed about its periphery to be received between said first and second surfaces, wherein said flat surfaces are moved relative to one another and to apply force and to crimp said stent onto the outside of said catheter.
a first substantially flat surface and a second substantially flat surface, said second flat surface spaced from said first flat surface a distance sufficient to allow a catheter having a stent deployed about its periphery to be received between said first and second surfaces, wherein said flat surfaces are moved relative to one another and to apply force and to crimp said stent onto the outside of said catheter.
2. The stent-loading device of claim 1, wherein said first and second substantially flat surfaces are formed from plates.
3. The stent-loading device of claim 2, wherein said flat surfaces are elastomeric.
4. The stent-loading device of claim 2, wherein said flat surfaces are spring biased towards one another.
5. The stent-loading device of claim 2, wherein said plates comprise a first stationary plate and a second moveable plate, said second moveable plate capable of moving along vertical and horizontal directions relative to said first stationary plate.
6. The stent-loading device of claim 5, further comprising a guide-bearing member guiding said second plate, wherein said second block has a channel received by said guide-bearing member.
7. The stent-loading device of claim 6, wherein said guide-bearing member has a vertically-extending groove received by a vertically-extending rail, said rail guiding said guide-bearing member along the vertical direction.
8. The stent-loading device of claim 7, further comprising a vertically-extending support having a vertically-extending channel, said rail fixed to said vertically-extending support, and said vertically-extending channel receiving a vertically-extending fixed rail, said fixed rail fixed to a base, with said base fixed to said first stationary plate.
9. The stent-loading device of claim 2, wherein said first and second surfaces are plates, and further comprising a housing supporting said plates.
10. The stent-loading device of claim 9, wherein said housing is sized to fit in a human hand.
11. The stent-loading device of claim 9, wherein said plates are constrained by said housing to move in substantially orthogonal directions.
12. The stent-loading device of claim 9, further comprising a plurality of springs attached to one of said plates, and a push plate attached to said springs.
13. The stent-loading device of claim 1, further comprising a force transducer to measure the force applied to at least one of said flat surfaces.
14. The stent-loading device of claim 13, further comprising means for indicating the force measured by said transducer as said stent is compressed onto said catheter.
15. A stent-loading device for loading a stent onto a catheter assembly, comprising:
a tubular member, having an open end to receive a stent;
an elastic bladder housed inside said tubular member, partitioning said tubular member into two portions, an open portion, including said open end, defining a stent-receiving portion and a closed portion, defining a fluid chamber;
whereby a stent is placed into said stent receiving portion and said fluid chamber is pressurized to cause said elastic bladder to compress said stent onto said catheter assembly.
a tubular member, having an open end to receive a stent;
an elastic bladder housed inside said tubular member, partitioning said tubular member into two portions, an open portion, including said open end, defining a stent-receiving portion and a closed portion, defining a fluid chamber;
whereby a stent is placed into said stent receiving portion and said fluid chamber is pressurized to cause said elastic bladder to compress said stent onto said catheter assembly.
16. The stent-loading device of claim 15, further comprising an inflation port, said port allowing fluid communication into said fluid chamber portion.
17. The stent-loading device of claim 16, further comprising means for providing fluid under pressure to said fluid chamber portion of said tubular member, through said inflation port.
18. A method of affixing an intravascular stent onto a catheter, comprising:
placing an intravascular stent onto a catheter, placing the portion of said catheter containing said stent in between two substantially flat surfaces, moving said surfaces relative to one another to compress said stent onto the catheter.
placing an intravascular stent onto a catheter, placing the portion of said catheter containing said stent in between two substantially flat surfaces, moving said surfaces relative to one another to compress said stent onto the catheter.
19. The method of affixing an intravascular stent onto a catheter according to claim 18, wherein said flat surfaces are moved along two directions.
20. The method of affixing an intravascular stent onto a catheter according to claim 19, wherein said two substantially flat surfaces are moved along two substantially orthogonal directions.
21. The method of affixing an intravascular stent onto a catheter according to claim 18, further comprising measuring and displaying the force applied to compress said stent onto said catheter.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/066,707 | 1993-05-24 | ||
US08/066,707 US5437083A (en) | 1993-05-24 | 1993-05-24 | Stent-loading mechanism |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2124050A1 true CA2124050A1 (en) | 1994-11-25 |
Family
ID=22071189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002124050A Abandoned CA2124050A1 (en) | 1993-05-24 | 1994-05-20 | Stent-loading mechanism |
Country Status (4)
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US (3) | US5437083A (en) |
EP (1) | EP0630623A3 (en) |
JP (1) | JPH06343705A (en) |
CA (1) | CA2124050A1 (en) |
Families Citing this family (112)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6451047B2 (en) | 1995-03-10 | 2002-09-17 | Impra, Inc. | Encapsulated intraluminal stent-graft and methods of making same |
US6579314B1 (en) * | 1995-03-10 | 2003-06-17 | C.R. Bard, Inc. | Covered stent with encapsulated ends |
US6264684B1 (en) | 1995-03-10 | 2001-07-24 | Impra, Inc., A Subsidiary Of C.R. Bard, Inc. | Helically supported graft |
US5628754A (en) * | 1995-08-01 | 1997-05-13 | Medtronic, Inc. | Stent delivery guide catheter |
IT1279628B1 (en) * | 1995-09-13 | 1997-12-16 | Xtrode Srl | DEVICE AND METHOD FOR ASSEMBLING A VASCULAR ENDOPROTHESIS ON A CATHETER FITTED WITH AN EXPANDABLE BALLOON |
US5746764A (en) * | 1995-12-04 | 1998-05-05 | Atrion Medical Products, Inc. | Stent compression instrument |
US5626604A (en) * | 1995-12-05 | 1997-05-06 | Cordis Corporation | Hand held stent crimping device |
US5836952A (en) | 1996-08-21 | 1998-11-17 | Cordis Corporation | Hand-held stent crimper |
US5725519A (en) * | 1996-09-30 | 1998-03-10 | Medtronic Instent Israel Ltd. | Stent loading device for a balloon catheter |
US5893867A (en) * | 1996-11-06 | 1999-04-13 | Percusurge, Inc. | Stent positioning apparatus and method |
IT1286780B1 (en) * | 1996-11-20 | 1998-07-17 | Bard Galway Ltd | DEVICE FOR ASSEMBLING A TUBULAR ENDOPROTHESIS FOR VASCULAR IMPLANTATION ON A TRANSPORT AND EXPANSION CATHETER |
US5911452A (en) * | 1997-02-04 | 1999-06-15 | Advanced Cardiovascular Systems, Inc. | Apparatus and method for mounting a stent onto a catheter |
US6027529A (en) * | 1997-04-15 | 2000-02-22 | Schneider (Usa) Inc | Protheses with selectively welded crossing strands |
US5972016A (en) * | 1997-04-22 | 1999-10-26 | Advanced Cardiovascular Systems, Inc. | Stent crimping device and method of use |
US5810873A (en) * | 1997-07-15 | 1998-09-22 | Advanced Cardiovascular Systems, Inc. | Stent crimping tool and method of use |
DE29714857U1 (en) * | 1997-08-20 | 1997-10-09 | Ziegerer Rainer | Device for deforming a grating-like, radially deformable pipe section |
US6167605B1 (en) | 1997-09-12 | 2001-01-02 | Advanced Cardiovascular Systems, Inc. | Collet type crimping tool |
US5972028A (en) * | 1997-10-07 | 1999-10-26 | Atrion Medical Products, Inc. | Stent holder/compression instrument |
US5992000A (en) * | 1997-10-16 | 1999-11-30 | Scimed Life Systems, Inc. | Stent crimper |
US6769161B2 (en) | 1997-10-16 | 2004-08-03 | Scimed Life Systems, Inc. | Radial stent crimper |
US6018857A (en) * | 1997-10-30 | 2000-02-01 | Ave Connaught | Device and method for mounting a stent onto a balloon catheter |
US5920975A (en) * | 1997-11-03 | 1999-07-13 | Advanced Cardiovascular Systems, Inc. | Stent crimping tool and method of use |
US6112316A (en) * | 1997-12-03 | 2000-08-29 | Micron Electronics, Inc. | System for use of bus parking states to communicate diagnostic information |
US6092219A (en) | 1997-12-03 | 2000-07-18 | Micron Technology, Inc. | Method for use of bus parking states to communicate diagnostic information |
US6082990A (en) * | 1998-02-17 | 2000-07-04 | Advanced Cardiovascular Systems, Inc. | Stent crimping tool |
US6024737A (en) | 1998-02-25 | 2000-02-15 | Advanced Cardiovascular Systems, Inc. | Stent crimping device |
EP0941713B1 (en) * | 1998-03-04 | 2004-11-03 | Schneider (Europe) GmbH | Device to insert an endoprosthesis into a catheter shaft |
US5931851A (en) * | 1998-04-21 | 1999-08-03 | Advanced Cardiovascular Systems, Inc. | Method and apparatus for rubber-tube crimping tool with premount stent |
US6009614A (en) * | 1998-04-21 | 2000-01-04 | Advanced Cardiovascular Systems, Inc. | Stent crimping tool and method of use |
DE19818541C2 (en) | 1998-04-24 | 2003-04-10 | Forschungszentrum Juelich Gmbh | Microbial production of substances from the aromatic metabolism / III |
US5893852A (en) | 1998-04-28 | 1999-04-13 | Advanced Cardiovascular Systems, Inc. | Stent crimping tool and method of use |
US6141855A (en) * | 1998-04-28 | 2000-11-07 | Advanced Cardiovascular Systems, Inc. | Stent crimping tool and method of use |
US5974652A (en) * | 1998-05-05 | 1999-11-02 | Advanced Cardiovascular Systems, Inc. | Method and apparatus for uniformly crimping a stent onto a catheter |
US6149680A (en) * | 1998-06-04 | 2000-11-21 | Scimed Life Systems, Inc. | Stent loading tool |
US6092273A (en) * | 1998-07-28 | 2000-07-25 | Advanced Cardiovascular Systems, Inc. | Method and apparatus for a stent crimping device |
US6096027A (en) * | 1998-09-30 | 2000-08-01 | Impra, Inc., A Subsidiary Of C.R. Bard, Inc. | Bag enclosed stent loading apparatus |
US6051002A (en) * | 1998-10-09 | 2000-04-18 | Advanced Cardiovascular Systems, Inc. | Stent crimping device and method of use |
US6074381A (en) * | 1998-10-22 | 2000-06-13 | Isostent, Inc. | Cylindrical roller stent crimper apparatus with radiation shield |
US5951540A (en) * | 1998-10-22 | 1999-09-14 | Medtronic, Inc. | Device and method for mounting stents |
US6125523A (en) | 1998-11-20 | 2000-10-03 | Advanced Cardiovascular Systems, Inc. | Stent crimping tool and method of use |
US6364870B1 (en) | 1998-12-22 | 2002-04-02 | Medinol Ltd. | Apparatus and method for securing a stent on a balloon |
SG76636A1 (en) | 1998-12-22 | 2000-11-21 | Medinol Ltd | Apparatus and method for securing a stent on a balloon |
EP1073384B1 (en) * | 1999-01-22 | 2008-04-02 | Gore Enterprise Holdings, Inc. | Low profile stent and graft combination |
US6558414B2 (en) | 1999-02-02 | 2003-05-06 | Impra, Inc. | Partial encapsulation of stents using strips and bands |
US6398803B1 (en) * | 1999-02-02 | 2002-06-04 | Impra, Inc., A Subsidiary Of C.R. Bard, Inc. | Partial encapsulation of stents |
US6066156A (en) | 1999-03-11 | 2000-05-23 | Advanced Cardiovascular Systems, Inc. | Temperature activated adhesive for releasably attaching stents to balloons |
US6090035A (en) * | 1999-03-19 | 2000-07-18 | Isostent, Inc. | Stent loading assembly for a self-expanding stent |
FR2791550A1 (en) * | 1999-03-29 | 2000-10-06 | Jean Francois Delforge | Setter for intraluminal endoprosthesis in cardiology uses pressurized inner chamber, and axial cells along axial channel to avoid channel to be crushed under pressure |
US6360577B2 (en) | 1999-09-22 | 2002-03-26 | Scimed Life Systems, Inc. | Apparatus for contracting, or crimping stents |
US6352547B1 (en) | 1999-09-22 | 2002-03-05 | Scimed Life Systems, Inc. | Stent crimping system |
US6387117B1 (en) | 1999-09-22 | 2002-05-14 | Scimed Life Systems, Inc. | Stent crimping system |
US6191119B1 (en) | 1999-10-15 | 2001-02-20 | Supergen, Inc. | Combination therapy including 9-nitro-20(S)-camptothecin |
US6481262B2 (en) | 1999-12-30 | 2002-11-19 | Advanced Cardiovascular Systems, Inc. | Stent crimping tool |
US6510722B1 (en) | 2000-05-10 | 2003-01-28 | Advanced Cardiovascular Systems, Inc. | Stent crimping tool for producing a grooved crimp |
US6629350B2 (en) | 2000-06-08 | 2003-10-07 | Tom Motsenbocker | Stent crimping apparatus and method |
US6568235B1 (en) | 2000-08-10 | 2003-05-27 | Advanced Cardiovascular Systems, Inc. | Assembly for crimping an intraluminal device or measuring the radial strength of the intraluminal device and method of use |
US6840081B2 (en) | 2000-08-10 | 2005-01-11 | Advanced Cardiovascular Systems, Inc. | Assembly for crimping an intraluminal device or measuring the radial strength of the intraluminal device and method of use |
US6783542B2 (en) | 2001-02-22 | 2004-08-31 | Scimed Life Systems, Inc | Crimpable balloon/stent protector |
JP2004525704A (en) | 2001-03-26 | 2004-08-26 | マシーン ソリューションズ インコーポレイテッド | Balloon folding technology |
US6739033B2 (en) | 2001-03-29 | 2004-05-25 | Scimed Life Systems, Inc. | Thermal regulation of a coated work-piece during the reconfiguration of the coated work-piece |
US6640412B2 (en) | 2001-04-26 | 2003-11-04 | Endovascular Technologies, Inc. | Method for loading a stent using a collapsing machine |
US7112055B1 (en) * | 2002-07-02 | 2006-09-26 | Endovascular Technologies, Inc. | Nitinol frame heating and setting mandrel |
US9480839B2 (en) | 2002-09-24 | 2016-11-01 | Medtronic, Inc. | Lead delivery device and method |
US9636499B2 (en) * | 2002-09-24 | 2017-05-02 | Medtronic, Inc. | Lead delivery device and method |
US9849279B2 (en) * | 2008-06-27 | 2017-12-26 | Medtronic, Inc. | Lead delivery device and method |
US8920432B2 (en) * | 2002-09-24 | 2014-12-30 | Medtronic, Inc. | Lead delivery device and method |
US8229572B2 (en) * | 2008-06-27 | 2012-07-24 | Medtronic, Inc. | Lead delivery device and method |
US6745445B2 (en) * | 2002-10-29 | 2004-06-08 | Bard Peripheral Vascular, Inc. | Stent compression method |
US6997946B2 (en) * | 2002-11-27 | 2006-02-14 | Boston Scientific Scimed, Inc. | Expandable stents |
US7152452B2 (en) * | 2002-12-26 | 2006-12-26 | Advanced Cardiovascular Systems, Inc. | Assembly for crimping an intraluminal device and method of use |
US6957152B1 (en) | 2002-12-30 | 2005-10-18 | Advanced Cardiovascular Systems, Inc. | System and computer-based method for tracking an implantable medical device characteristic during a coating process |
US6702845B1 (en) | 2003-01-17 | 2004-03-09 | Gore Enterprise Holdings, Inc. | Compacted implantable medical devices and method of compacting such devices |
US7487579B2 (en) * | 2003-03-12 | 2009-02-10 | Boston Scientific Scimed, Inc. | Methods of making medical devices |
US7533514B2 (en) * | 2003-04-25 | 2009-05-19 | Boston Scientific Scimed, Inc. | Method and apparatus for automated handling of medical devices during manufacture |
US7316147B2 (en) * | 2004-01-29 | 2008-01-08 | Boston Scientific Scimed, Inc. | Apparatuses for crimping and loading of intraluminal medical devices |
US7207204B2 (en) * | 2004-02-26 | 2007-04-24 | Boston Scientific Scimed, Inc. | Crimper |
US7143625B2 (en) * | 2004-04-16 | 2006-12-05 | Boston Scientific Scimed, Inc. | Stent crimper |
US7021114B2 (en) * | 2004-04-16 | 2006-04-04 | Boston Scientific Scimed, Inc. | Stent crimper |
US7389670B1 (en) | 2004-07-26 | 2008-06-24 | Abbott Laboratories | Stent crimping system |
US7316148B2 (en) * | 2005-02-15 | 2008-01-08 | Boston Scientific Scimed, Inc. | Protective sheet loader |
US7563400B2 (en) * | 2005-04-12 | 2009-07-21 | Advanced Cardiovascular Systems, Inc. | Method of stent mounting to form a balloon catheter having improved retention of a drug delivery stent |
US7947207B2 (en) | 2005-04-12 | 2011-05-24 | Abbott Cardiovascular Systems Inc. | Method for retaining a vascular stent on a catheter |
US7717936B2 (en) * | 2005-04-18 | 2010-05-18 | Salviac Limited | Device for loading an embolic protection filter into a catheter |
AU2005331495A1 (en) | 2005-04-29 | 2006-11-09 | Arterial Remodelling Technologies, Inc. | Stent crimping |
US9078781B2 (en) | 2006-01-11 | 2015-07-14 | Medtronic, Inc. | Sterile cover for compressible stents used in percutaneous device delivery systems |
US20080004689A1 (en) * | 2006-01-19 | 2008-01-03 | Linda Jahnke | Systems and Methods for Making Medical Devices |
US20070239271A1 (en) * | 2006-04-10 | 2007-10-11 | Than Nguyen | Systems and methods for loading a prosthesis onto a minimally invasive delivery system |
US20070288080A1 (en) * | 2006-06-07 | 2007-12-13 | Maccollum Michael W | Stent expanding device |
US20070288034A1 (en) * | 2006-06-07 | 2007-12-13 | Maccollum Michael W | Stent Expanding device |
US7886419B2 (en) * | 2006-07-18 | 2011-02-15 | Advanced Cardiovascular Systems, Inc. | Stent crimping apparatus and method |
US20080127707A1 (en) * | 2006-11-30 | 2008-06-05 | Abbott Laboratories | Stent crimping assembly and method |
US8256263B2 (en) * | 2007-11-05 | 2012-09-04 | Cook Medical Technologies Llc | Apparatus and method for compressing a stent |
US8196279B2 (en) | 2008-02-27 | 2012-06-12 | C. R. Bard, Inc. | Stent-graft covering process |
US8336179B2 (en) * | 2008-05-20 | 2012-12-25 | Seagate Technology | Fixture assembly |
US8225474B2 (en) * | 2008-05-30 | 2012-07-24 | Boston Scientific Scimed, Inc. | Stent crimping device |
US9775989B2 (en) * | 2008-06-27 | 2017-10-03 | Medtronic, Inc. | Lead delivery device and method |
US9775990B2 (en) * | 2008-06-27 | 2017-10-03 | Medtronic, Inc. | Lead delivery device and method |
US11931523B2 (en) | 2008-06-27 | 2024-03-19 | Medtronic, Inc. | Lead delivery device and method |
WO2010002931A1 (en) | 2008-07-01 | 2010-01-07 | Endologix, Inc. | Catheter system |
US7770466B2 (en) * | 2008-07-02 | 2010-08-10 | Abbott Cardiovascular Systems Inc. | Method for measuring stent dislodgement force |
US9895272B2 (en) * | 2008-12-30 | 2018-02-20 | The Procter & Gamble Company | Absorbent articles with primary and secondary indicating |
JP5665149B2 (en) | 2009-08-28 | 2015-02-04 | メドトロニック 3エフ セラピュティックス インコーポレイテッド | Transapical transport device and method of use |
CA2772344C (en) * | 2009-08-28 | 2018-05-01 | 3F Therapeutics, Inc. | Crimping device and method of use |
DE102010008382A1 (en) | 2010-02-17 | 2011-08-18 | Transcatheter Technologies GmbH, 93053 | A method of crimping or folding a medical implant on a device for introducing or introducing same using zero-pressure crimping and devices |
WO2012023979A2 (en) * | 2010-08-17 | 2012-02-23 | St. Jude Medical, Inc. | A device for collapsing and loading a heart valve into a minimally invasive delivery system |
JP6294669B2 (en) | 2011-03-01 | 2018-03-14 | エンドロジックス、インク | Catheter system and method of use thereof |
US10010412B2 (en) | 2011-07-27 | 2018-07-03 | Edwards Lifesciences Corporation | Conical crimper |
US10271975B2 (en) | 2013-03-15 | 2019-04-30 | Atrium Medical Corporation | Stent device having reduced foreshortening and recoil and method of making same |
JP2018524025A (en) | 2015-06-30 | 2018-08-30 | エンドロジックス、インク | Lock assembly for coupling guidewire to delivery system |
US10357363B2 (en) * | 2016-06-09 | 2019-07-23 | Medtronic Vascular, Inc. | Transcatheter valve delivery system with crimped prosthetic heart valve |
US10716691B2 (en) | 2016-06-24 | 2020-07-21 | Edwards Lifesciences Corporation | Compact crimping device |
CN109501286A (en) * | 2018-12-28 | 2019-03-22 | 迅得机械(东莞)有限公司 | A kind of sacculus dilating catheter assembly machine |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US430928A (en) * | 1890-06-24 | Device for administering medicine to animals | ||
US696289A (en) * | 1901-07-26 | 1902-03-25 | Maryland Shoe Machinery Company | Machine for inserting protectors in heels and soles of shoes. |
GB159065A (en) * | 1919-12-09 | 1921-02-24 | William Levi Secord | Improvements relating to machine and other vices and like work holding or setting appliances |
GB1209650A (en) * | 1967-11-28 | 1970-10-21 | Duffield Ltd F | Improved crimping, clamping, moulding or other compression device |
US4070745A (en) * | 1976-07-21 | 1978-01-31 | Precision Dynamics Corporation | Crimping tool |
US4353240A (en) * | 1980-01-15 | 1982-10-12 | Toolema Ab | Crimping tool |
SE430881B (en) * | 1981-02-20 | 1983-12-19 | Lars Erik Trygg | bottle grippers |
US4606347A (en) * | 1983-03-25 | 1986-08-19 | Thomas J. Fogarty | Inverted balloon catheter having sealed through lumen |
US4733665C2 (en) * | 1985-11-07 | 2002-01-29 | Expandable Grafts Partnership | Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft |
US4800882A (en) * | 1987-03-13 | 1989-01-31 | Cook Incorporated | Endovascular stent and delivery system |
US4907336A (en) * | 1987-03-13 | 1990-03-13 | Cook Incorporated | Method of making an endovascular stent and delivery system |
GB8708476D0 (en) * | 1987-04-09 | 1987-05-13 | Charlesworth D | Making polymer material |
US5133732A (en) * | 1987-10-19 | 1992-07-28 | Medtronic, Inc. | Intravascular stent |
US4961291A (en) * | 1989-08-03 | 1990-10-09 | Lagassee Richard L | Glass holder tool |
US4989909A (en) * | 1989-08-17 | 1991-02-05 | Franks Casing Crew And Rental Tools, Inc. | Friction grip for tubular goods |
JPH04183211A (en) * | 1990-11-13 | 1992-06-30 | Sumitomo Wiring Syst Ltd | Wire stripping method and wire untwisting device |
US5183085A (en) * | 1991-09-27 | 1993-02-02 | Hans Timmermans | Method and apparatus for compressing a stent prior to insertion |
US5628754A (en) * | 1995-08-01 | 1997-05-13 | Medtronic, Inc. | Stent delivery guide catheter |
US5626604A (en) * | 1995-12-05 | 1997-05-06 | Cordis Corporation | Hand held stent crimping device |
US5630830A (en) * | 1996-04-10 | 1997-05-20 | Medtronic, Inc. | Device and method for mounting stents on delivery systems |
-
1993
- 1993-05-24 US US08/066,707 patent/US5437083A/en not_active Expired - Lifetime
-
1994
- 1994-05-20 CA CA002124050A patent/CA2124050A1/en not_active Abandoned
- 1994-05-24 JP JP6109704A patent/JPH06343705A/en not_active Withdrawn
- 1994-05-24 EP EP94303698A patent/EP0630623A3/en not_active Withdrawn
-
1995
- 1995-02-17 US US08/390,096 patent/US5546646A/en not_active Expired - Lifetime
-
1996
- 1996-07-17 US US08/682,103 patent/US5738674A/en not_active Expired - Lifetime
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US5546646A (en) | 1996-08-20 |
US5738674A (en) | 1998-04-14 |
EP0630623A2 (en) | 1994-12-28 |
EP0630623A3 (en) | 1995-09-20 |
JPH06343705A (en) | 1994-12-20 |
US5437083A (en) | 1995-08-01 |
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Legal Events
Date | Code | Title | Description |
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FZDE | Discontinued |