CA2133598A1 - Non-occlusive adhesive patch for applying medication to the skin - Google Patents

Non-occlusive adhesive patch for applying medication to the skin

Info

Publication number
CA2133598A1
CA2133598A1 CA002133598A CA2133598A CA2133598A1 CA 2133598 A1 CA2133598 A1 CA 2133598A1 CA 002133598 A CA002133598 A CA 002133598A CA 2133598 A CA2133598 A CA 2133598A CA 2133598 A1 CA2133598 A1 CA 2133598A1
Authority
CA
Canada
Prior art keywords
skin
medication
backing
reservoir
patch
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002133598A
Other languages
French (fr)
Other versions
CA2133598C (en
Inventor
David Rolf
Elisabeth K. Sjoblom Urmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Axogen Inc
Original Assignee
Lectec Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22821546&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2133598(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lectec Corp filed Critical Lectec Corp
Publication of CA2133598A1 publication Critical patent/CA2133598A1/en
Application granted granted Critical
Publication of CA2133598C publication Critical patent/CA2133598C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/00987—Apparatus or processes for manufacturing non-adhesive dressings or bandages
    • A61F13/00991—Apparatus or processes for manufacturing non-adhesive dressings or bandages for treating webs, e.g. for moisturising, coating, impregnating or applying powder
    • A61F13/00995—Apparatus or processes for manufacturing non-adhesive dressings or bandages for treating webs, e.g. for moisturising, coating, impregnating or applying powder for mechanical treatments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00544—Plasters form or structure
    • A61F2013/00646—Medication patches, e.g. transcutaneous

Abstract

A non-occlusive medication patch (32) to be applied to the skin includes a porous self-supporting backing layer (10) to give the patch the required integrity and strength by acting as a supporting framework for other components, and a flexible hydrophilic pressure-sensitive adhesive reservoir (20) comprising a natural or synthetic polymer for the sustained release of medication to be absorbed topically through the skin into the body of a patient. The reservoir has two portions: first, an external coating layer (24) with an exposed lower skin-contacting surface (24b) that forms a pressure-sensitive bond with the skin, and second, an upper internal portion (24a) which infiltrates the porous backing (10) and becomes solidified therein after being applied so that the reservoir and the backing are unified, enabling the backing itself to act as a storage location for the medication-containing reservoir (20). The medication within the reservoir migrates over time from within the backing (10) through the lower coating layer (24b) and passes through the skin to provide sus-tained release of the medication into the body of a patient.
CA002133598A 1994-03-30 1994-10-04 Non-occlusive adhesive patch for applying medication to the skin Expired - Lifetime CA2133598C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/219,982 US5536263A (en) 1994-03-30 1994-03-30 Non-occulusive adhesive patch for applying medication to the skin
US08/219,982 1994-03-30

Publications (2)

Publication Number Publication Date
CA2133598A1 true CA2133598A1 (en) 1995-10-01
CA2133598C CA2133598C (en) 2002-03-05

Family

ID=22821546

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002133598A Expired - Lifetime CA2133598C (en) 1994-03-30 1994-10-04 Non-occlusive adhesive patch for applying medication to the skin

Country Status (11)

Country Link
US (5) US5536263A (en)
EP (1) EP0674913B1 (en)
JP (1) JPH07265353A (en)
AT (1) ATE269744T1 (en)
AU (1) AU676623B2 (en)
CA (1) CA2133598C (en)
DE (1) DE69433859T2 (en)
DK (1) DK0674913T3 (en)
ES (1) ES2224102T3 (en)
FI (1) FI950465A (en)
NO (1) NO951217L (en)

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US5741510A (en) 1998-04-21
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DE69433859T2 (en) 2005-06-23
JPH07265353A (en) 1995-10-17
FI950465A0 (en) 1995-02-02
NO951217D0 (en) 1995-03-29
EP0674913A2 (en) 1995-10-04
CA2133598C (en) 2002-03-05
US6096334A (en) 2000-08-01
US6096333A (en) 2000-08-01
FI950465A (en) 1995-10-01
ATE269744T1 (en) 2004-07-15
NO951217L (en) 1995-10-02
ES2224102T3 (en) 2005-03-01
US6361790B1 (en) 2002-03-26
EP0674913B1 (en) 2004-06-23
DE69433859D1 (en) 2004-07-29
US5536263A (en) 1996-07-16

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