CA2136419A1 - Blood extraction flow control calibration system and method - Google Patents

Blood extraction flow control calibration system and method

Info

Publication number
CA2136419A1
CA2136419A1 CA002136419A CA2136419A CA2136419A1 CA 2136419 A1 CA2136419 A1 CA 2136419A1 CA 002136419 A CA002136419 A CA 002136419A CA 2136419 A CA2136419 A CA 2136419A CA 2136419 A1 CA2136419 A1 CA 2136419A1
Authority
CA
Canada
Prior art keywords
flow rate
flow
blood
flow control
curve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002136419A
Other languages
French (fr)
Other versions
CA2136419C (en
Inventor
Paul R. Prince
Robin C. Huff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Paul R. Prince
Robin C. Huff
Baxter International, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paul R. Prince, Robin C. Huff, Baxter International, Inc. filed Critical Paul R. Prince
Publication of CA2136419A1 publication Critical patent/CA2136419A1/en
Application granted granted Critical
Publication of CA2136419C publication Critical patent/CA2136419C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D7/00—Control of flow
    • G05D7/06—Control of flow characterised by the use of electric means
    • G05D7/0617—Control of flow characterised by the use of electric means specially adapted for fluid materials
    • G05D7/0629—Control of flow characterised by the use of electric means specially adapted for fluid materials characterised by the type of regulator means
    • G05D7/0676—Control of flow characterised by the use of electric means specially adapted for fluid materials characterised by the type of regulator means by action on flow sources
    • G05D7/0682—Control of flow characterised by the use of electric means specially adapted for fluid materials characterised by the type of regulator means by action on flow sources using a plurality of flow sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
    • A61M1/301—Details
    • A61M1/303—Details having a reservoir for treated blood to be returned
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
    • A61M1/301—Details
    • A61M1/305—Control of inversion point between collection and re-infusion phase
    • A61M1/306—Pressure control, e.g. using substantially rigid closed or gas buffered or elastic reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3639—Blood pressure control, pressure transducers specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
    • A61M1/3656—Monitoring patency or flow at connection sites; Detecting disconnections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3344—Measuring or controlling pressure at the body treatment site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3351—Controlling upstream pump pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3355—Controlling downstream pump pressure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/13—Infusion monitoring

Abstract

A method and system for calibrating and controlling the with-drawal of a fluid, such as blood, from a fluid source, such as a blood vessel, includes a fluid pump (26), a pressure sensor (24), a flow rate sensor, and a microprocessor based flow control subsystem. The flow control subsystem optimizes the flow rate by sensing zero flow rate pressure within the subject, making a plurality of periodic flow path pressure measurements and extrapolating a calibration flow rate curve (I10). A control curve (130) is generated by utilizing the zero-flow rate pressure point ( 100), the slope of the calibration curve ( 110), and an empirically predetermined pressure offset value (150). The blood pump (26) is then operated at a maximum speed that is limited by the flow control curve ( 130) to maximize flow without occlusion or collapse of the blood vessel during blood withdrawal. The method and system of the invention is particularly applicable to automated apheresis system.
CA002136419A 1992-06-01 1993-05-28 Blood extraction flow control calibration system and method Expired - Fee Related CA2136419C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/891,527 1992-06-01
US07/891,527 US5536237A (en) 1992-06-01 1992-06-01 Blood extraction flow control calibration system and method
PCT/US1993/005147 WO1993024159A1 (en) 1992-06-01 1993-05-28 Blood extraction flow control calibration system and method

Publications (2)

Publication Number Publication Date
CA2136419A1 true CA2136419A1 (en) 1993-12-09
CA2136419C CA2136419C (en) 2003-05-13

Family

ID=25398349

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002136419A Expired - Fee Related CA2136419C (en) 1992-06-01 1993-05-28 Blood extraction flow control calibration system and method

Country Status (6)

Country Link
US (1) US5536237A (en)
EP (1) EP0643594B1 (en)
JP (1) JP3232483B2 (en)
CA (1) CA2136419C (en)
DE (1) DE69323744T2 (en)
WO (1) WO1993024159A1 (en)

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US5906589A (en) * 1996-11-13 1999-05-25 Cobe Laboratories, Inc. Method and apparatus for occlusion monitoring using pressure waveform analysis
JP4638986B2 (en) 1998-10-16 2011-02-23 テルモ メディカル コーポレイション Blood processing equipment
US6526357B1 (en) 1999-08-09 2003-02-25 Gambro, Inc. Associated parameter measuring and/or monitoring such as in the evaluation of pressure differences
US7006896B1 (en) * 1999-10-13 2006-02-28 Graco Minnesota Inc. Sealant dispensing correction method
SE517051C2 (en) 1999-12-10 2002-04-09 Tetra Laval Holdings & Finance Continuous device in a distribution equipment
US7169352B1 (en) 1999-12-22 2007-01-30 Gambro, Inc. Extracorporeal blood processing methods and apparatus
DE60035474T2 (en) 1999-12-22 2008-03-13 Gambro Inc., Lakewood Device for extracorporeal blood treatment
US7608053B2 (en) * 2000-01-10 2009-10-27 Caridianbct, Inc. Extracorporeal blood processing methods with return-flow alarm
US6514226B1 (en) 2000-02-10 2003-02-04 Chf Solutions, Inc. Method and apparatus for treatment of congestive heart failure by improving perfusion of the kidney
US7430478B2 (en) 2000-03-01 2008-09-30 Caridian Bct, Inc. Blood processing information system with blood loss equivalency tracking
WO2001065463A2 (en) * 2000-03-01 2001-09-07 Gambro, Inc. Extracorporeal blood processing information management system
US6691047B1 (en) * 2000-03-16 2004-02-10 Aksys, Ltd. Calibration of pumps, such as blood pumps of dialysis machine
US6287608B1 (en) 2000-04-11 2001-09-11 Intellicardia, Inc. Method and apparatus for treatment of congestive heart failure by improving perfusion of the kidney by infusion of a vasodilator
US6890315B1 (en) * 2000-05-23 2005-05-10 Chf Solutions, Inc. Method and apparatus for vein fluid removal in heart failure
US6887214B1 (en) 2000-09-12 2005-05-03 Chf Solutions, Inc. Blood pump having a disposable blood passage cartridge with integrated pressure sensors
US6533747B1 (en) 2000-05-23 2003-03-18 Chf Solutions, Inc. Extracorporeal circuit for peripheral vein fluid removal
US6468241B1 (en) 2000-10-26 2002-10-22 Chf Solutions, Inc. Artificial kidney set with electronic key
US6585675B1 (en) * 2000-11-02 2003-07-01 Chf Solutions, Inc. Method and apparatus for blood withdrawal and infusion using a pressure controller
US6689083B1 (en) 2000-11-27 2004-02-10 Chf Solutions, Inc. Controller for ultrafiltration blood circuit which prevents hypotension by monitoring osmotic pressure in blood
US6706007B2 (en) * 2000-12-29 2004-03-16 Chf Solutions, Inc. Feedback control of ultrafiltration to prevent hypotension
US6773412B2 (en) 2001-04-13 2004-08-10 Chf Solutions, Inc. User interface for blood treatment device
US6796955B2 (en) * 2002-02-14 2004-09-28 Chf Solutions, Inc. Method to control blood and filtrate flowing through an extracorporeal device
US7704454B1 (en) 2003-10-08 2010-04-27 Caridianbct, Inc. Methods and devices for processing blood
US8038639B2 (en) 2004-11-04 2011-10-18 Baxter International Inc. Medical fluid system with flexible sheeting disposable unit
US20060009727A1 (en) * 2004-04-08 2006-01-12 Chf Solutions Inc. Method and apparatus for an extracorporeal control of blood glucose
US7303540B2 (en) * 2004-04-26 2007-12-04 Chf Solutions, Inc. User interface for blood treatment device
US8303482B2 (en) * 2004-09-07 2012-11-06 Micromed Method and system for physiologic control of a blood pump
US20100094114A1 (en) * 2008-10-09 2010-04-15 Mark Ries Robinson Use of multiple calibration solutions with an analyte sensor with use in an automated blood access system
US20100168535A1 (en) * 2006-04-12 2010-07-01 Mark Ries Robinson Methods and apparatuses related to blood analyte measurement system
US20090054754A1 (en) * 2007-08-21 2009-02-26 Mcmahon Dave Clinician-controlled semi-automated medication management
US8323194B2 (en) * 2009-12-18 2012-12-04 Inlight Solutions, Inc. Detection of bubbles during hemodynamic monitoring when performing automated measurement of blood constituents
US20090048535A1 (en) * 2007-08-13 2009-02-19 Mark Ries Robinson Detecting Cross-contamination in Blood Measurements with a Multilumen Catheter
WO2007059476A2 (en) * 2005-11-15 2007-05-24 Luminous Medical, Inc. Blood analyte determinations
US20090088615A1 (en) * 2007-10-01 2009-04-02 Mark Ries Robinson Indwelling Fiber Optic Probe for Blood Glucose Measurements
US20090156975A1 (en) * 2007-11-30 2009-06-18 Mark Ries Robinson Robust System and Methods for Blood Access
US8092414B2 (en) 2005-11-09 2012-01-10 Nxstage Medical, Inc. Diaphragm pressure pod for medical fluids
US7981070B2 (en) * 2006-05-04 2011-07-19 Abatis Medical Technologies, Ltd. Internal tourniquet for automatically controlling hemostasis within a joint capsule
WO2009029677A1 (en) * 2007-08-27 2009-03-05 Quest Medical, Inc. Self-adaptive piston blood pump
DE112012002327T5 (en) 2011-05-31 2014-03-27 Nxstage Medical, Inc. Pressure measuring device, methods and systems
US9733805B2 (en) 2012-06-26 2017-08-15 Terumo Bct, Inc. Generating procedures for entering data prior to separating a liquid into components
JP7261791B2 (en) 2017-09-28 2023-04-20 テルモ株式会社 Biological Component Collection Device, Biological Component Collection System, and Method of Operating the Biological Component Collection System
WO2019065812A1 (en) 2017-09-28 2019-04-04 Terumo Kabushiki Kaisha Biological component collection system and circuit internal pressure acquisition method
CN111201049B (en) * 2017-10-13 2022-08-16 心脏器械股份有限公司 Dynamic HQ for closed loop control
JP7303209B2 (en) * 2018-03-26 2023-07-04 テルモ株式会社 Biological component collection system and method of operating the biological component collection system

Family Cites Families (5)

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US4392849A (en) * 1981-07-27 1983-07-12 The Cleveland Clinic Foundation Infusion pump controller
US4468219A (en) * 1983-12-20 1984-08-28 International Business Machines Corporation Pump flow rate compensation system
US4710164A (en) * 1984-05-01 1987-12-01 Henry Ford Hospital Automated hemodialysis control based upon patient blood pressure and heart rate
EP0188451B1 (en) * 1984-06-29 1991-12-11 BAXTER INTERNATIONAL INC. (a Delaware corporation) Blood extraction and reinfusion flow control system and method
US4795314A (en) * 1987-08-24 1989-01-03 Cobe Laboratories, Inc. Condition responsive pump control utilizing integrated, commanded, and sensed flowrate signals

Also Published As

Publication number Publication date
US5536237A (en) 1996-07-16
CA2136419C (en) 2003-05-13
WO1993024159A1 (en) 1993-12-09
DE69323744D1 (en) 1999-04-08
EP0643594B1 (en) 1999-03-03
JP3232483B2 (en) 2001-11-26
EP0643594A1 (en) 1995-03-22
DE69323744T2 (en) 1999-11-04
JPH07507462A (en) 1995-08-24

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