CA2142301A1 - Monitoring method - Google Patents

Monitoring method

Info

Publication number
CA2142301A1
CA2142301A1 CA002142301A CA2142301A CA2142301A1 CA 2142301 A1 CA2142301 A1 CA 2142301A1 CA 002142301 A CA002142301 A CA 002142301A CA 2142301 A CA2142301 A CA 2142301A CA 2142301 A1 CA2142301 A1 CA 2142301A1
Authority
CA
Canada
Prior art keywords
ovulation
subject
individual human
analyte concentration
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002142301A
Other languages
French (fr)
Other versions
CA2142301C (en
Inventor
Michael Catt
John Coley
Paul James Davis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alere Switzerland GmbH
Original Assignee
Michael Catt
John Coley
Paul James Davis
Unilever Plc
Inverness Medical Switzerland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michael Catt, John Coley, Paul James Davis, Unilever Plc, Inverness Medical Switzerland Gmbh filed Critical Michael Catt
Publication of CA2142301A1 publication Critical patent/CA2142301A1/en
Application granted granted Critical
Publication of CA2142301C publication Critical patent/CA2142301C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0012—Ovulation-period determination
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors

Abstract

A method of monitoring the status of a current ovulation cycle of an individual human female subject, involving testing of the body fluid concentration of an analyte of significance in relation to the status of the ovulation cycle, such as urinary E3G, during at least part of the pre-ovulation phase of the current ovulation cycle of the individual subject, and identification from the results of such testing of an analyte concentration change indicative of imminent ovulation, relative to an analyte concentration reference value that has been adapted to the individual human subject on the basis of analyte concentration test data obtained from the individual human subject during one or more previous ovulation cycles.
CA002142301A 1992-08-21 1993-08-10 Monitoring method Expired - Fee Related CA2142301C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929217865A GB9217865D0 (en) 1992-08-21 1992-08-21 Monitoring method
GB9217865.6 1992-08-21
PCT/EP1993/002147 WO1994004925A1 (en) 1992-08-21 1993-08-10 Monitoring method

Publications (2)

Publication Number Publication Date
CA2142301A1 true CA2142301A1 (en) 1994-03-03
CA2142301C CA2142301C (en) 2003-02-11

Family

ID=10720774

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002142301A Expired - Fee Related CA2142301C (en) 1992-08-21 1993-08-10 Monitoring method

Country Status (20)

Country Link
US (1) US6454726B1 (en)
EP (2) EP0656119B1 (en)
JP (2) JP2761291B2 (en)
KR (1) KR950703148A (en)
AT (1) ATE150180T1 (en)
AU (1) AU4709393A (en)
BG (1) BG62062B1 (en)
BR (1) BR9306940A (en)
CA (1) CA2142301C (en)
CZ (2) CZ285802B6 (en)
DE (1) DE69308858T2 (en)
DK (1) DK0656119T3 (en)
ES (1) ES2099965T3 (en)
FI (1) FI950760A (en)
GB (1) GB9217865D0 (en)
GR (1) GR3023402T3 (en)
NZ (1) NZ254822A (en)
PL (2) PL174930B1 (en)
RU (1) RU95106504A (en)
WO (1) WO1994004925A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6927064B1 (en) * 1994-06-29 2005-08-09 Inverness Medical Switzerland Gmbh Fertility computing method
DE69619236D1 (en) * 1996-09-27 2002-03-21 Unilever Plc monitoring procedures
ATE231971T1 (en) * 1996-09-27 2003-02-15 Inverness Medical Switzerland TEST KIT AND DEVICES
GB2335983A (en) * 1998-04-02 1999-10-06 Unilever Plc Estimating time of maximum fertility
US6493579B1 (en) 1999-08-20 2002-12-10 Cardiac Pacemakers, Inc. System and method for detection enhancement programming
US6289248B1 (en) * 1999-08-20 2001-09-11 Cardiac Pacemakers, Inc. System and method for detecting and displaying parameter interactions
GB0025245D0 (en) * 2000-10-14 2000-11-29 Lee Helen Multiple target detection
GB0105273D0 (en) * 2001-03-02 2001-04-18 Unilever Plc Improvements in or relating to assessment of fertility
US6592529B2 (en) 2001-07-31 2003-07-15 Pheromone Sciences Corp. Method and device for predicting the fertile phase of women
DE10297227T5 (en) * 2001-09-18 2004-09-02 Inverness Medical Switzerland Gmbh Improvement in or regarding evidence of impaired fertility
US20040181167A1 (en) * 2003-03-13 2004-09-16 Carney Fiona Patricia Method and kits for monitoring women's health
US7315378B2 (en) * 2003-06-04 2008-01-01 Inverness Medical Switzerland Gmbh Optical arrangement for assay reading device
GB2402475A (en) * 2003-06-04 2004-12-08 Inverness Medical Switzerland Analyte assay reading providing prompt result declaration
US7239394B2 (en) * 2003-06-04 2007-07-03 Inverness Medical Switzerland Gmbh Early determination of assay results
US7317532B2 (en) * 2003-06-04 2008-01-08 Inverness Medical Switzerland Gmbh Flow sensing for determination of assay results
US7413550B2 (en) 2003-10-16 2008-08-19 Kimberly-Clark Worldwide, Inc. Visual indicating device for bad breath
US7977103B2 (en) 2006-04-20 2011-07-12 Kimberly-Clark Worldwide, Inc. Method for detecting the onset of ovulation
US7613672B2 (en) 2006-04-27 2009-11-03 Cardiac Pacemakers, Inc. Medical device user interface automatically resolving interaction between programmable parameters
GB2450351B (en) 2007-06-20 2012-01-18 Cozart Bioscience Ltd Monitoring an Immunoassay
WO2009034563A2 (en) * 2007-09-14 2009-03-19 Nanocomms Patents Limited An analysis system
US7526945B1 (en) 2008-07-01 2009-05-05 Kosasky Harold J System and method for measuring extensional rheology of bodily fluids
WO2010061613A1 (en) * 2008-11-28 2010-06-03 株式会社日立製作所 Method, system and kit for supporting pregnancy
US20100312138A1 (en) * 2009-06-09 2010-12-09 Philip George Chelf Regas Determining and/or Monitoring Physiological Conditions in Mammals
EP2555871B1 (en) 2010-04-07 2021-01-13 Biosensia Patents Limited Flow control device for assays
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
US9939385B2 (en) 2011-09-09 2018-04-10 Church & Dwight Co., Inc. Systems, methods, and test kits for analyte variation detection
US9588113B2 (en) 2012-02-22 2017-03-07 Church & Dwight Co., Inc. Methods for electronic analyte assaying
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
CN108051590B (en) 2013-09-13 2020-12-11 Symbolics有限责任公司 Lateral flow assay using two-dimensional test and control signal readout modes

Family Cites Families (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL109802C (en) 1954-10-27
NL109082C (en) 1954-11-13
FR1304254A (en) 1961-10-20 1962-09-21 Ruler for reading a menstrual cycle temperature graph
US3436186A (en) 1964-02-21 1969-04-01 Consolidated Lab Inc Test method for assessing ovulatory function
US3434801A (en) 1964-02-21 1969-03-25 Colab Lab Inc Diagnostic test material for determination of ovulatory function and method for production of said test material
US3406016A (en) 1965-02-01 1968-10-15 Raymond O. Foster Means for detecting the fertile period
US3406015A (en) 1965-02-01 1968-10-15 Raymond O. Foster Means for detecting the fertile period
GB1203619A (en) 1967-01-25 1970-08-26 Weston Lab Inc Method for detecting the fertile period
US3991174A (en) 1970-07-20 1976-11-09 Rafa Laboratories Ltd. Method of determining concentration of luteinizing hormone in body fluid
US3749089A (en) 1971-10-26 1973-07-31 L J Derr Ovulation monitor
US3968011A (en) 1973-02-16 1976-07-06 Alza Corporation Test implement and test method for colorimetrically determining whether a female is fertile or pregnant
US3875013A (en) 1973-02-16 1975-04-01 Alza Corp Article for detecting the fertile period and method for using same
US4013066A (en) 1974-05-23 1977-03-22 Ovutime, Inc. Processes for menstrual cycle phase determination
US3924609A (en) 1974-07-02 1975-12-09 Robert Friedenberg Detector device and process for detecting ovulation
FR2290876A2 (en) 1974-07-31 1976-06-11 Briand Henry Menstrual cycle fertility indicator watch - has blue coloured dial for safe period, and irregularity adjustments
US3986494A (en) 1974-10-30 1976-10-19 The Trustees Of The University Of Pennsylvania Method of predicting and detecting ovulation
US4010738A (en) 1974-10-30 1977-03-08 The Trustees Of The University Of Pennsylvania Method of predicting and detecting ovulation
US4059986A (en) 1974-11-12 1977-11-29 Ovutime, Inc. Mucus testing processes and devices
US3926037A (en) 1975-03-14 1975-12-16 Ovutime Inc Processes and devices for determining properties of bodily mucus
US4002056A (en) 1975-03-14 1977-01-11 Ovutime, Inc. Processes and devices for determining properties of viscous fluids
IT1041291B (en) 1975-08-21 1980-01-10 Raggiotti G BODY TEMPERATURE CONTROL AND INDICATION DEVICE
US4036212A (en) 1975-12-22 1977-07-19 Karuhn Richard F Method of predetermining time of ovulation in women and in animals to control conception
CA1048001A (en) 1976-03-05 1979-02-06 Manfred E. Weisshaar Menstrual calculator for a human female
US4151833A (en) 1976-04-20 1979-05-01 Polishuk W Z Method and apparatus for detecting the onset of ovulation
US4072045A (en) 1976-09-10 1978-02-07 Ovutime, Inc. Viscometer for indicating rheological properties of fluids having high and low viscosity components
US4151831A (en) 1976-11-15 1979-05-01 Safetime Monitors, Inc. Fertility indicator
US4148304A (en) 1976-11-29 1979-04-10 Bmd Development Trust Device for measuring ovulation
US4119089A (en) 1977-02-02 1978-10-10 Trustees Of The University Of Pennsylvania Method of predicting and determining ovulation by monitoring the concentration of volatile sulfur-containing compounds present in mouth air
US4123510A (en) 1977-04-11 1978-10-31 American Home Products Corp. (Del.) Method for the determination of gonadotropins
US4208187A (en) 1977-12-19 1980-06-17 American Home Products Corporation Diagnostic test
US4261371A (en) 1978-01-18 1981-04-14 Reading Iii William H Method and apparatus for determining ovulation in female mammalia
DE2803152A1 (en) 1978-01-25 1979-07-26 Hans Rueckstaedter Data recording pregnancy prevention instrument - includes cassette with medical data, electrical thermometer, digital clock, controlled by microprocessor and operating keys
CH626224B (en) 1978-08-09 1900-01-01 Bioself Int Inc POCKET CALCULATOR FOR THE PREDICTION OF TIME CYCLES.
US4232215A (en) 1978-10-02 1980-11-04 Hanley John P Human reproduction indexing device
DE2847397A1 (en) 1978-11-02 1980-05-08 Norbert Dipl Ing Kluge Microprocessor family planning calculator - is programmed to evaluate safety period of birth control based upon menstrual cycle
US4246907A (en) 1979-01-29 1981-01-27 Bullock Russel F Method for identifying an ovulation phase within a menstrual cycle of a woman
JPS6035018B2 (en) 1979-02-19 1985-08-12 シャープ株式会社 women's thermometer
ATE5105T1 (en) 1979-06-07 1983-11-15 Bioself International Inc. CALCULATOR FOR FAMILY PLANNING.
US4396020A (en) 1979-12-21 1983-08-02 National Research Development Corporation Measurement of basal body temperature
JPS56118630A (en) 1980-02-23 1981-09-17 Sharp Corp Electronic clinical thermometer
US4312360A (en) 1980-02-25 1982-01-26 Conway Julian C Device to aid in the determination of ovulation in a female mamalian
US4443851A (en) 1980-07-03 1984-04-17 Lin Kin Yuan Automatic recording, indicating and predicting device for gynecophysiological cycles
DE3037977A1 (en) 1980-10-08 1982-05-13 Bashir-Elahi, Sohrab, 5300 Bonn Female fertility monitoring instrument - uses mechanical or electronic device with timer to give indicating colour
US4381121A (en) 1980-11-03 1983-04-26 Hanley John P Human reproduction indexing device
US4385125A (en) 1980-11-14 1983-05-24 Monell Chemical Senses Center Method detecting ovulation by monitoring dodecanol concentration in saliva
US4408905A (en) 1981-06-11 1983-10-11 Ehrenkranz Joel R L Urinary temperature measurement device
JPS5849134A (en) 1981-09-19 1983-03-23 株式会社コルポ Menstrual cycle meter for female
US4450239A (en) 1981-09-23 1984-05-22 Northwestern University Method of determining pregnanediol in female urine and test device for use therein
US4465077A (en) * 1981-11-12 1984-08-14 Howard Schneider Apparatus and method of determining fertility status
CH648662A5 (en) 1981-12-01 1985-03-29 Ares Nv ELECTRONIC INSTRUMENT FOR THE CONTROL AND TREATMENT OF FEMALE INFERTILITY.
IE54109B1 (en) 1982-02-10 1989-06-21 Boots Celltech Diagnostics Assay
CA1183080A (en) 1982-03-12 1985-02-26 William F. Coulson Use of synthetic bifunctional ligand for the immunometric determination of the concentration ratio of two solutes
US4475158A (en) 1982-03-15 1984-10-02 University Of Florida Microprocessor based instrument for detecting shift in basal body temperature in women
US4534362A (en) 1982-05-07 1985-08-13 University Patents, Inc. Method and apparatus for detection of fertility
US4614715A (en) 1982-05-14 1986-09-30 The Board Of Trustees Of The University Of Illinois Predictive test for impending ovulation in mammals
DE3221999A1 (en) 1982-06-11 1983-04-14 Gert Barnbeck Device for the determination of the fertile and infertile days of women for use in natural birth control
DE3223657C1 (en) 1982-06-24 1983-11-03 Ernst Dr. Dr. med. 2800 Bremen Menke Device for detecting the time of ovulation in women
US4466445A (en) 1982-09-16 1984-08-21 University Of Florida Systems and devices for measurement of urine temperature, particularly for detecting the shift in basal body temperature in women
US4498481A (en) 1982-09-28 1985-02-12 Lemke Judith K Estrus cycle monitoring system
DE3247750A1 (en) 1982-12-23 1984-06-28 Wolfram Dipl.-Ing. 2161 Hammah Ruff Fully electronic wristwatch with temperature measuring device for family planning
US4557273A (en) 1982-12-27 1985-12-10 Stoller Kenneth P Method and apparatus for detecting ovulation
WO1984003379A1 (en) 1983-02-24 1984-08-30 Bioself Int Inc Apparatus indicating the present fertility conditions of a person
DE3314442A1 (en) 1983-04-21 1984-11-08 Bandera, Jan Eric, Dipl.-Ing., 7000 Stuttgart Electronic cycle thermometer
FR2549167B1 (en) 1983-07-13 1988-01-29 Applic Mach Motrices HYDRAULIC DISTRIBUTOR FOR EQUIPPING AN AIRCRAFT CONTROL
DE3325598A1 (en) 1983-07-15 1985-01-31 Werner 5413 Bendorf Weiland Arrangement for measuring the internal body temperature of humans and animals
DE3342251A1 (en) 1983-11-23 1985-05-30 Werner 5413 Bendorf Weiland Method of measuring the body temperature of human beings and animals, especially for determining ovulation
DE3343020A1 (en) 1983-11-28 1985-06-05 Ludwig 8771 Roden Rauh Apparatus for the determination of the days when women are contraceptive
GB8420116D0 (en) 1984-08-08 1984-09-12 Elchemtec Ltd Apparatus for monitoring redox reactions
US4685471A (en) 1984-09-11 1987-08-11 Zetek, Inc. Method and apparatus for predicting and detecting the onset of ovulation
US4770186A (en) 1985-03-20 1988-09-13 Zetek, Inc. Method and apparatus for predicting and detecting the onset of ovulation
US4691714A (en) 1984-10-15 1987-09-08 Adamtek Corporation Rheological testing apparatus and method
US4670401A (en) 1985-01-25 1987-06-02 Monell Chemical Senses Center Axillary androstenol and dehydroepiandrosterone as fertile period onset indicators
US5248593A (en) 1985-03-06 1993-09-28 Boehringer Mannheim Gmbh Process and reagent for the determination of the luteinizing hormone and monoclonal antibodies suitable thereof
DE3509503A1 (en) 1985-03-16 1986-09-25 Hermann-Josef Dr. 5300 Bonn Frohn DEVICE FOR RECEIVING REGULATION
DE3528964A1 (en) 1985-08-13 1987-02-19 Angela Knoop Measuring device for the determination of the menstrual cycle
GB8526741D0 (en) 1985-10-30 1985-12-04 Boots Celltech Diagnostics Binding assay device
GB2186977A (en) 1986-02-25 1987-08-26 Benytone Corp Fertility indicating thermometer
DE3609956A1 (en) 1986-03-25 1987-10-01 Helmut Schulte (Ladies') watch (chronometer) with a device for monitoring the female cycle and the intake of contraceptive hormones (the pill)
US4779627A (en) 1986-04-04 1988-10-25 The Academy Of Applied Sciences, Inc. Process and apparatus for determining female ovulation time by measurement of saliva viscoelasticity
US4921808A (en) 1986-06-25 1990-05-01 The Albany Medical College Of Union University Method for determining follicle stimulating hormone
DE3752074T2 (en) 1986-12-22 1997-09-18 Semex Japan Hamamatsu Kk MAMMAL DEVICE FOR DISPLAYING THE FERTILIZED PERIOD
US4788984A (en) * 1987-01-30 1988-12-06 Procare Industries Ltd. Method and kit for use in conceiving a child of a desired gender
US5091170A (en) * 1987-03-17 1992-02-25 Daniel Navot Fertility prediction by use of clomiphene challenge test
EP0286743B1 (en) 1987-04-14 1994-03-09 The Academy of Applied Science Inc. Process and apparatus for determining female ovulation time by measurement of saliva viscoelasticity
DE560410T1 (en) * 1987-04-27 2001-12-20 Unilever Nv Test device for carrying out specific binding tests.
DE3802479A1 (en) 1988-01-28 1989-08-10 Uebe Thermometer Gmbh Method and device for determining the ovulation period of humans or animals by means of electric detection of the deviation in body temperature
US5118630A (en) * 1988-11-04 1992-06-02 Quidel Corporation Method for determining periodic infertility in females
GB8903626D0 (en) 1989-02-17 1989-04-05 Unilever Plc Methods and devices for use therein
GB8903627D0 (en) 1989-02-17 1989-04-05 Unilever Plc Assays
DE3922859A1 (en) 1989-07-12 1991-01-24 Bosch Gmbh Robert METHOD FOR CONTROLLING FUEL MEASUREMENT IN AN INTERNAL COMBUSTION ENGINE
US5209238A (en) 1989-08-17 1993-05-11 Sundhar Shaam P Electronic ovulation monitor
US5050612A (en) 1989-09-12 1991-09-24 Matsumura Kenneth N Device for computer-assisted monitoring of the body
FR2652092A1 (en) 1989-09-15 1991-03-22 Fama Process for measuring the peroxidase activity of cervical glairy mucus
JPH03133440A (en) 1989-10-18 1991-06-06 Nishitomo:Kk Clinical thermometer for ladies
US5120660A (en) * 1989-12-05 1992-06-09 International Canine Genetics, Inc. Method for canine fertility detection
US5043888A (en) 1990-04-12 1991-08-27 Uriarte Jorge E Fertility indicator
IT1245325B (en) 1990-08-06 1994-09-19 U P F Di Zanieri Ugo Pietro Or BODY TEMPERATURE REMOTE MEASURING DEVICE
JPH04130682A (en) 1990-09-20 1992-05-01 Mitsubishi Kasei Corp Piezoelectric ceramic composition for actuator
IL97115A (en) 1991-01-31 1995-11-27 Yissum Res Dev Co Fertility probe
US5253648A (en) * 1991-10-11 1993-10-19 Spacelabs Medical, Inc. Method and apparatus for excluding artifacts from automatic blood pressure measurements
DE69431334T2 (en) 1993-11-12 2003-09-18 Inverness Medical Switzerland Device for reading test strips

Also Published As

Publication number Publication date
CA2142301C (en) 2003-02-11
BG62062B1 (en) 1999-01-29
DE69308858D1 (en) 1997-04-17
ES2099965T3 (en) 1997-06-01
GB9217865D0 (en) 1992-10-07
KR950703148A (en) 1995-08-23
PL174930B1 (en) 1998-10-30
CZ12996A3 (en) 1999-07-14
CZ286019B6 (en) 1999-12-15
AU4709393A (en) 1994-03-15
RU95106504A (en) 1997-02-10
FI950760A0 (en) 1995-02-20
FI950760A (en) 1995-02-20
NZ254822A (en) 1997-04-24
JP2761291B2 (en) 1998-06-04
CZ285802B6 (en) 1999-11-17
BR9306940A (en) 1999-01-12
JPH08500670A (en) 1996-01-23
PL307571A1 (en) 1995-05-29
GR3023402T3 (en) 1997-08-29
JPH10115614A (en) 1998-05-06
DK0656119T3 (en) 1997-09-15
BG99436A (en) 1995-12-29
EP0656119A1 (en) 1995-06-07
EP0754950A1 (en) 1997-01-22
US6454726B1 (en) 2002-09-24
CZ45195A3 (en) 1999-07-14
DE69308858T2 (en) 1997-07-24
EP0656119B1 (en) 1997-03-12
WO1994004925A1 (en) 1994-03-03
ATE150180T1 (en) 1997-03-15

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