CA2152410A1 - Mediators suitable for the electrochemical regeneration of nadh, nadph or analogs thereof - Google Patents

Mediators suitable for the electrochemical regeneration of nadh, nadph or analogs thereof

Info

Publication number
CA2152410A1
CA2152410A1 CA002152410A CA2152410A CA2152410A1 CA 2152410 A1 CA2152410 A1 CA 2152410A1 CA 002152410 A CA002152410 A CA 002152410A CA 2152410 A CA2152410 A CA 2152410A CA 2152410 A1 CA2152410 A1 CA 2152410A1
Authority
CA
Canada
Prior art keywords
nadph
nadh
analogs
electrochemical regeneration
mediators suitable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002152410A
Other languages
French (fr)
Other versions
CA2152410C (en
Inventor
Paul F. Corey
Matthew K. Musho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Healthcare LLC
Original Assignee
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Corp filed Critical Bayer Corp
Publication of CA2152410A1 publication Critical patent/CA2152410A1/en
Application granted granted Critical
Publication of CA2152410C publication Critical patent/CA2152410C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/817—Enzyme or microbe electrode

Abstract

Disclosed is an electrode suitable for the electro-chemical regeneration of the co-enzymes NADH and NADPH.
The electrode has imparted on its surface a mediator func-tion which is a 3-methylene-3H-phenothiazine or a 3-meth-ylene-3H-phenoxazine compound.
CA002152410A 1994-09-29 1995-06-22 Mediators suitable for the electrochemical regeneration of nadh, nadph or analogs thereof Expired - Fee Related CA2152410C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/314,781 1994-09-29
US08/314,718 US5498542A (en) 1994-09-29 1994-09-29 Electrode mediators for regeneration of NADH and NADPH

Publications (2)

Publication Number Publication Date
CA2152410A1 true CA2152410A1 (en) 1996-03-30
CA2152410C CA2152410C (en) 2004-02-17

Family

ID=23221146

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002152410A Expired - Fee Related CA2152410C (en) 1994-09-29 1995-06-22 Mediators suitable for the electrochemical regeneration of nadh, nadph or analogs thereof

Country Status (6)

Country Link
US (1) US5498542A (en)
EP (1) EP0704535B1 (en)
JP (1) JP3814314B2 (en)
AU (1) AU689630B2 (en)
CA (1) CA2152410C (en)
DE (1) DE69524175T2 (en)

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US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US8262614B2 (en) 2003-05-30 2012-09-11 Pelikan Technologies, Inc. Method and apparatus for fluid injection
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
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US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
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Also Published As

Publication number Publication date
DE69524175T2 (en) 2002-05-02
DE69524175D1 (en) 2002-01-10
EP0704535A3 (en) 1997-07-16
AU689630B2 (en) 1998-04-02
US5498542A (en) 1996-03-12
JPH08100284A (en) 1996-04-16
CA2152410C (en) 2004-02-17
AU3293695A (en) 1996-04-18
EP0704535A2 (en) 1996-04-03
EP0704535B1 (en) 2001-11-28
JP3814314B2 (en) 2006-08-30

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EEER Examination request
MKLA Lapsed
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Effective date: 20110622