CA2153010A1 - Filter for separating photoactive agent - Google Patents
Filter for separating photoactive agentInfo
- Publication number
- CA2153010A1 CA2153010A1 CA002153010A CA2153010A CA2153010A1 CA 2153010 A1 CA2153010 A1 CA 2153010A1 CA 002153010 A CA002153010 A CA 002153010A CA 2153010 A CA2153010 A CA 2153010A CA 2153010 A1 CA2153010 A1 CA 2153010A1
- Authority
- CA
- Canada
- Prior art keywords
- biological fluid
- photoactive agent
- plasma protein
- agent
- filter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
- A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
- A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation
Abstract
Disclosed are methods, systems and devices for processing a biological fluid. Specifically, disclosed is a method for processing a biological fluid comprising the steps of removing red blood cells from a biological fluid to produce a plasma protein-containing biological fluid that is substantially free of red blood cells, placing the plasma protein-containing biological fluid in contact with a photoactive agent, activating the photoactive agent, separating the photoactive agent from the plasma protein-containing biological fluid by passing the agent-containing fluid through a photoactive agent binding arrangement including carbon fibers, and recovering the plasma protein-containing biological fluid.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/337,365 US5660731A (en) | 1994-11-08 | 1994-11-08 | Filter for separating photoactive agent |
US08/337,365 | 1994-11-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2153010A1 true CA2153010A1 (en) | 1996-05-09 |
CA2153010C CA2153010C (en) | 2002-09-17 |
Family
ID=23320276
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002153010A Expired - Fee Related CA2153010C (en) | 1994-11-08 | 1995-06-29 | Filter for separating photoactive agent |
Country Status (2)
Country | Link |
---|---|
US (1) | US5660731A (en) |
CA (1) | CA2153010C (en) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5935092A (en) | 1990-12-20 | 1999-08-10 | Baxter International Inc. | Systems and methods for removing free and entrained contaminants in plasma |
AU1601595A (en) * | 1994-01-10 | 1995-08-01 | Hemasure, Inc. | Device and process for removing leukocytes and viral inactivating agents from blood |
US6544727B1 (en) * | 1995-06-07 | 2003-04-08 | Cerus Corporation | Methods and devices for the removal of psoralens from blood products |
FR2735790B1 (en) * | 1995-06-22 | 1997-07-25 | Inst Textile De France | PROCESS FOR ADSORBING ANTI-MICROBIAL AGENTS CONTAINED IN A BIOLOGICAL LIQUID AND APPARATUS FOR CARRYING OUT SAID METHOD |
EP0892599A4 (en) * | 1996-04-09 | 2001-05-16 | Therakos Inc | Method for removal of psoralens from biological fluids |
US6190855B1 (en) | 1996-10-28 | 2001-02-20 | Baxter International Inc. | Systems and methods for removing viral agents from blood |
US6168718B1 (en) | 1996-11-08 | 2001-01-02 | Pall Corporation | Method for purifying blood plasma and apparatus suitable therefor |
US20010009756A1 (en) | 1998-01-06 | 2001-07-26 | Derek Hei | Flow devices for the reduction of compounds from biological compositions and methods of use |
US20010018179A1 (en) | 1998-01-06 | 2001-08-30 | Derek J. Hei | Batch devices for the reduction of compounds from biological compositions containing cells and methods of use |
WO1999034839A1 (en) | 1998-01-06 | 1999-07-15 | Cerus Corporation | Methods for quenching pathogen inactivators in biological materials |
US7611831B2 (en) * | 1998-01-06 | 2009-11-03 | Cerus Corporation | Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix |
US6099734A (en) * | 1998-07-08 | 2000-08-08 | Baxter International Inc. | Apparatus, membranes and methods for removing organic compounds from a biological fluid |
US6908553B1 (en) | 1998-07-08 | 2005-06-21 | Baxter International Inc. | Composite membrane with particulate matter substantially immobilized therein |
US7288195B2 (en) * | 1999-05-28 | 2007-10-30 | Bio/Data Corporation | Method and apparatus for directly sampling a fluid for microfiltration |
US7445756B2 (en) * | 1999-06-03 | 2008-11-04 | Fenwal, Inc. | Fluid processing sets and organizers for the same |
US7025877B1 (en) * | 1999-06-03 | 2006-04-11 | Baxter International Inc. | Processing set for processing and treating a biological fluid |
FR2797403B1 (en) * | 1999-08-09 | 2002-03-15 | Maco Pharma Sa | TRANSFUSION LINE WITH MEANS FOR FILTERING A COLORED SUBSTANCE |
US8389687B2 (en) * | 2000-10-23 | 2013-03-05 | Shanbrom Technologies, Llc | Polyvinylpyrrolidone cryoprecipitate extraction of clotting factors |
US6881731B1 (en) * | 2000-10-23 | 2005-04-19 | Shanbrom Technologies, Llc | Enhancers for microbiological disinfection |
US7411006B2 (en) * | 2000-10-23 | 2008-08-12 | Shanbrom Technologies, Llc | Enhanced production of blood clotting factors and fibrin fabric |
US7264608B2 (en) * | 2001-12-05 | 2007-09-04 | Fenwal, Inc. | Manual processing systems and methods for providing blood components conditioned for pathogen inactivation |
WO2003078023A1 (en) | 2002-03-14 | 2003-09-25 | Baxter International Inc. | Compound removal device |
US7534348B2 (en) * | 2003-09-12 | 2009-05-19 | Fenwal, Inc. | Flow-through removal device and system using such device |
EP1518573B1 (en) * | 2003-09-23 | 2006-08-23 | Fresenius Hemocare Italia S.r.l. | Filter, purification device and method for the removal of substances from blood products |
US20050137517A1 (en) * | 2003-12-19 | 2005-06-23 | Baxter International Inc. | Processing systems and methods for providing leukocyte-reduced blood components conditioned for pathogen inactivation |
WO2006050328A1 (en) * | 2004-10-29 | 2006-05-11 | Cerus Corporation | Improved quenching methods for red blood cell inactivation process |
DE102006014184A1 (en) * | 2006-03-24 | 2007-09-27 | Heim, Heidrun | Deactivating unwanted organisms in blood plasma, especially viruses, involves adding porphyrin to blood plasma immediately after extracting it from blood and irradiating mixture with xenon radiation |
US20080234622A1 (en) * | 2007-03-20 | 2008-09-25 | Gambro Bct Inc. | Methods and Systems for Preparing Blood Products |
AU2009233807B2 (en) | 2008-04-09 | 2014-11-27 | Cerus Corporation | Improved quenching methods for red blood cell pathogen inactivation |
EP2459248B1 (en) * | 2009-06-02 | 2019-05-22 | biolitec Unternehmensbeteiligungs II AG | A novel method for microbial depletion in human blood and blood products using antimicrobial photodynamic therapy |
EP2501822B1 (en) * | 2009-11-17 | 2017-08-16 | E. R. Squibb & Sons, L.L.C. | Methods for enhanced protein production |
GB0921528D0 (en) * | 2009-12-09 | 2010-01-27 | Mast Carbon Internat Ltd | Carbon and its use in blood cleansing applications |
JP6154678B2 (en) * | 2013-06-28 | 2017-06-28 | 旭化成メディカル株式会社 | Drug removal filter, drug removal system, and drug removal method |
JP6240490B2 (en) * | 2013-12-12 | 2017-11-29 | 旭化成メディカル株式会社 | Leukocyte and drug removal method, leukocyte and drug removal filter, and leukocyte and drug removal system |
US10159778B2 (en) | 2014-03-24 | 2018-12-25 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
US9968738B2 (en) | 2014-03-24 | 2018-05-15 | Fenwal, Inc. | Biological fluid filters with molded frame and methods for making such filters |
US9782707B2 (en) | 2014-03-24 | 2017-10-10 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
US9796166B2 (en) | 2014-03-24 | 2017-10-24 | Fenwal, Inc. | Flexible biological fluid filters |
US10376627B2 (en) | 2014-03-24 | 2019-08-13 | Fenwal, Inc. | Flexible biological fluid filters |
EP3300748B1 (en) * | 2016-09-21 | 2021-11-03 | Fenwal, Inc. | Disposable fluid circuits for extracorporeal photopheresis with integrated source of photoactive agent |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3989740A (en) * | 1974-04-22 | 1976-11-02 | Celanese Corporation | Method of preparing polyalkylene glycol acrylates |
JPS61275228A (en) * | 1985-03-14 | 1986-12-05 | バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテツド | Photodynamic inactivity of virus in therapeutical protein composition |
JPS62266073A (en) * | 1986-05-14 | 1987-11-18 | テルモ株式会社 | Apparatus for purifying body fluids |
US4925572A (en) * | 1987-10-20 | 1990-05-15 | Pall Corporation | Device and method for depletion of the leukocyte content of blood and blood components |
US4880548A (en) * | 1988-02-17 | 1989-11-14 | Pall Corporation | Device and method for separating leucocytes from platelet concentrate |
US4950665A (en) * | 1988-10-28 | 1990-08-21 | Oklahoma Medical Research Foundation | Phototherapy using methylene blue |
US5229012A (en) * | 1989-05-09 | 1993-07-20 | Pall Corporation | Method for depletion of the leucocyte content of blood and blood components |
DE69028775T2 (en) * | 1989-05-11 | 1997-05-07 | Oklahoma Med Res Found | ANTIVIRAL THERAPY USING THIAZINE AND XANTHENE DYES |
US5258126A (en) * | 1989-09-12 | 1993-11-02 | Pall Corporation | Method for obtaining platelets |
US5100564A (en) * | 1990-11-06 | 1992-03-31 | Pall Corporation | Blood collection and processing system |
US5418130A (en) * | 1990-04-16 | 1995-05-23 | Cryopharm Corporation | Method of inactivation of viral and bacterial blood contaminants |
ZA912842B (en) * | 1990-04-16 | 1992-03-25 | Cryopharm Corp | Method of inactivation of viral and bacterial blood contaminants |
US5126054A (en) * | 1990-05-24 | 1992-06-30 | Pall Corporation | Venting means |
US5217627A (en) * | 1990-11-06 | 1993-06-08 | Pall Corporation | System and method for processing biological fluid |
EP0516839B1 (en) * | 1990-12-20 | 1999-11-24 | Baxter International Inc. | Systems and methods for simultaneously removing free and entrained contaminants in fluids like blood using photoactive therapy and cellular separation techniques |
DE9102709U1 (en) * | 1991-03-07 | 1991-05-23 | Blutspendedienst Der Landesverbaende Des Deutschen Roten Kreuzes Niedersachsen, Oldenburg Und Bremen Gemeinnuetzige Gmbh, 3257 Springe, De | |
CA2089005C (en) * | 1991-06-21 | 1999-01-19 | John Chapman | Method for inactivating pathogens in a body fluid |
US5288605A (en) * | 1992-03-02 | 1994-02-22 | Steritech, Inc. | Methods for inactivating bacteria in blood preparations with 8-methoxypsoralen |
US6207107B1 (en) * | 1992-10-05 | 2001-03-27 | Baxter International Inc. | Steam sterilizable system for inactivating viral contaminants in body fluids |
KR960703167A (en) * | 1993-06-23 | 1996-06-19 | 존 더블유. 아담슨 | SYSTEM FOR VIRAL INACTIVATION OF BLOOD |
US6319662B1 (en) * | 1993-12-17 | 2001-11-20 | Baxter International Inc. | Method and apparatus for removing viral contaminants from a body fluid |
-
1994
- 1994-11-08 US US08/337,365 patent/US5660731A/en not_active Expired - Fee Related
-
1995
- 1995-06-29 CA CA002153010A patent/CA2153010C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2153010C (en) | 2002-09-17 |
US5660731A (en) | 1997-08-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |