CA2172265A1 - Transdermal delivery device containing an estrogen - Google Patents

Transdermal delivery device containing an estrogen

Info

Publication number
CA2172265A1
CA2172265A1 CA002172265A CA2172265A CA2172265A1 CA 2172265 A1 CA2172265 A1 CA 2172265A1 CA 002172265 A CA002172265 A CA 002172265A CA 2172265 A CA2172265 A CA 2172265A CA 2172265 A1 CA2172265 A1 CA 2172265A1
Authority
CA
Canada
Prior art keywords
estrogen
delivery device
device containing
transdermal delivery
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002172265A
Other languages
French (fr)
Other versions
CA2172265C (en
Inventor
Spiros Fotinos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lavipharm SA
Original Assignee
Spiros Fotinos
Lavipharm S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spiros Fotinos, Lavipharm S.A. filed Critical Spiros Fotinos
Publication of CA2172265A1 publication Critical patent/CA2172265A1/en
Application granted granted Critical
Publication of CA2172265C publication Critical patent/CA2172265C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol

Abstract

A composition for use in a transdermal drug delivery system is described. The composition comprises an adhesive, an estrogen, and a flux enhancer.
CA002172265A 1994-07-26 1995-07-25 Transdermal delivery device containing an estrogen Expired - Fee Related CA2172265C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GR940100369 1994-07-26
GR94100369 1994-07-26
PCT/EP1995/002938 WO1996003119A1 (en) 1994-07-26 1995-07-25 Transdermal delivery device containing an estrogen

Publications (2)

Publication Number Publication Date
CA2172265A1 true CA2172265A1 (en) 1996-02-08
CA2172265C CA2172265C (en) 2004-04-20

Family

ID=10941554

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002172265A Expired - Fee Related CA2172265C (en) 1994-07-26 1995-07-25 Transdermal delivery device containing an estrogen

Country Status (11)

Country Link
US (1) US5925373A (en)
EP (1) EP0735867B1 (en)
JP (1) JP3043071B2 (en)
AT (1) ATE240722T1 (en)
AU (1) AU703074B2 (en)
BR (1) BR9506279A (en)
CA (1) CA2172265C (en)
DE (1) DE69530832T2 (en)
GR (1) GR1002079B (en)
NZ (1) NZ291161A (en)
WO (1) WO1996003119A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19548332A1 (en) * 1995-12-22 1997-07-10 Rotta Res Bv hormone patches
GB9803032D0 (en) * 1998-02-12 1998-04-08 Ethical Pharmaceuticals Uk Lim Transdermal delivery devices
DE10000333A1 (en) * 2000-01-07 2001-07-19 Lohmann Therapie Syst Lts Pharmaceutical composition for the transdermal administration of hormones with a permeation-improving additive
US20040062794A1 (en) * 2002-09-30 2004-04-01 Lee Shulman 17Beta- estradiol/levonorgestrel transdermal patch for hormone replacement therapy
KR20060123551A (en) * 2004-01-14 2006-12-01 라비팜 라보라토리즈, 인크. Transdermal delivery device for dihydropyridine type calcium antagonists containing at least one fatty acid
WO2008045461A2 (en) * 2006-10-11 2008-04-17 Oregon Health & Science University Transdermal diethylstilbestrol for treating prostate cancer
DE102006050558B4 (en) 2006-10-26 2009-03-26 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing norelgestromin for contraception and hormone replacement
US20090098191A1 (en) * 2007-10-16 2009-04-16 Anderson Christopher G Use of bases to stabilize transdermal formulations
US20160199317A1 (en) * 2013-08-30 2016-07-14 3M Innovative Properties Company Estradiol containing transdermal drug delivery systems and compositions

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531545A1 (en) * 1985-09-04 1987-03-05 Goedecke Ag MEDICINAL PRODUCTS CONTAINING CALCIUM ANTAGONISTS AND THEIR USE
US5023084A (en) * 1986-12-29 1991-06-11 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
US4789547A (en) * 1987-06-17 1988-12-06 Warner-Lambert Company Transdermal matrix system
US4906475A (en) * 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
JP2931002B2 (en) * 1988-02-26 1999-08-09 ライカー ラボラトリース インコーポレーテッド Skin permeation estradiol delivery system
US5223261A (en) * 1988-02-26 1993-06-29 Riker Laboratories, Inc. Transdermal estradiol delivery system
EP0371496A1 (en) * 1988-12-01 1990-06-06 Schering Corporation Compositions for transdermal delivery of estradiol
EP0399432B1 (en) * 1989-05-25 1994-06-22 Takeda Chemical Industries, Ltd. Transdermal therapeutic composition
US5262165A (en) * 1992-02-04 1993-11-16 Schering Corporation Transdermal nitroglycerin patch with penetration enhancers
JP2718433B2 (en) * 1989-09-08 1998-02-25 シグナス インコーポレイテッド Solid matrix system for transdermal drug delivery
US5252334A (en) * 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
AU6712090A (en) * 1989-10-13 1991-05-16 Watson Laboratories, Inc. Drug delivery systems and matrix therefor
AR246186A1 (en) * 1989-11-17 1994-07-29 Beta Pharm Co Procedure for manufacturing a device for administering stradiol through the skin.
EP0483370B1 (en) * 1990-05-17 1995-03-29 Hisamitsu Pharmaceutical Co., Inc. Percutaneous preparation containing estradiol
AU653156B2 (en) * 1990-06-14 1994-09-22 Dermamed Transdermal administration to humans and animals
CA2091883A1 (en) * 1990-10-29 1992-04-30 Robert M. Gale Transdermal contraceptive formulations, methods and devices
US5152997A (en) * 1990-12-11 1992-10-06 Theratech, Inc. Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective levels
US5705185A (en) * 1991-09-25 1998-01-06 Beta Pharmaceuticals Co. Transdermal delivery of estradiol and process for manufacturing said device
US5518734A (en) * 1991-09-25 1996-05-21 Beta Pharmaceuticals Co. Transdermal delivery system for estradiol and process for manufacturing said device
IT1253265B (en) * 1991-11-25 1995-07-14 Rotta Research Lab ACRYLIC-BASED ADHESIVE COPOLYMER MATRIX PREPARATION FOR THE TRANSDERMAL EXTRADIOL RELEASE.
MX9207344A (en) * 1991-12-16 1993-07-01 Alza Corp IMPROVED FORMULATIONS THAT HAVE HYDROPHOBIC IMPROVERS OF TRANSDERMIC PENETRATION AND METHOD TO PROVIDE IT.
US5629019A (en) * 1992-02-27 1997-05-13 Alza Corporation Formulations with hydrophobic permeation enhancers
US5264219A (en) * 1992-08-07 1993-11-23 Minnesota Mining And Manufacturing Company Transdermal drug delivery backing
US5762952A (en) * 1993-04-27 1998-06-09 Hercon Laboratories Corporation Transdermal delivery of active drugs
DE4336557C2 (en) * 1993-05-06 1997-07-17 Lohmann Therapie Syst Lts Estradiol-containing transdermal therapeutic system, process for its preparation and its use
US5670142A (en) * 1996-07-08 1997-09-23 Donald Neudecker Treatment for itch of chicken pox

Also Published As

Publication number Publication date
JP3043071B2 (en) 2000-05-22
ATE240722T1 (en) 2003-06-15
DE69530832D1 (en) 2003-06-26
BR9506279A (en) 1997-08-12
CA2172265C (en) 2004-04-20
DE69530832T2 (en) 2004-04-22
WO1996003119A1 (en) 1996-02-08
NZ291161A (en) 1998-04-27
AU3221495A (en) 1996-02-22
US5925373A (en) 1999-07-20
JPH09503229A (en) 1997-03-31
EP0735867A1 (en) 1996-10-09
EP0735867B1 (en) 2003-05-21
AU703074B2 (en) 1999-03-11
GR1002079B (en) 1995-12-05

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20130725