CA2172350A1 - Preparation of autologous plasma and fibrin gel - Google Patents

Preparation of autologous plasma and fibrin gel

Info

Publication number
CA2172350A1
CA2172350A1 CA002172350A CA2172350A CA2172350A1 CA 2172350 A1 CA2172350 A1 CA 2172350A1 CA 002172350 A CA002172350 A CA 002172350A CA 2172350 A CA2172350 A CA 2172350A CA 2172350 A1 CA2172350 A1 CA 2172350A1
Authority
CA
Canada
Prior art keywords
plasma
outlet
membrane
inlets
pumps
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002172350A
Other languages
French (fr)
Other versions
CA2172350C (en
Inventor
Elaine Whitmore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethicon Inc
Original Assignee
Johnson and Johnson Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson and Johnson Medical Inc filed Critical Johnson and Johnson Medical Inc
Publication of CA2172350A1 publication Critical patent/CA2172350A1/en
Application granted granted Critical
Publication of CA2172350C publication Critical patent/CA2172350C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Abstract

A system for preparing autologous plasma comprises a single use filter unit having two inlets in fluid communication with each other, an outlet, and a filtration membrane selectively permeable to blood plasma separating the inlets from the outlet. Manually operable, single use pumps, preferably syringes, connect to the inlets. A flow path is defined along the membrane between the pumps, whereby, whole blood can be repeatedly exchanged between the two pumps, past the membrane, to cause plasma to flow across the membrane and out of the outlet. A syringe can collect plasma from the outlet. Plasma thus collected can be simultaneously applied with a thrombin solution to a site on the body, thereby forming a fibrin gel.
CA002172350A 1995-03-24 1996-03-21 Preparation of autologous plasma and fibrin gel Expired - Fee Related CA2172350C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/410,028 1995-03-24
US08/410,028 US5674394A (en) 1995-03-24 1995-03-24 Single use system for preparation of autologous plasma

Publications (2)

Publication Number Publication Date
CA2172350A1 true CA2172350A1 (en) 1996-09-25
CA2172350C CA2172350C (en) 2006-10-31

Family

ID=23622916

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002172350A Expired - Fee Related CA2172350C (en) 1995-03-24 1996-03-21 Preparation of autologous plasma and fibrin gel

Country Status (10)

Country Link
US (4) US5674394A (en)
EP (1) EP0733378B1 (en)
JP (1) JP4173205B2 (en)
AT (1) ATE240132T1 (en)
CA (1) CA2172350C (en)
DE (1) DE69628072T2 (en)
DK (1) DK0733378T3 (en)
ES (1) ES2197935T3 (en)
NO (1) NO313737B1 (en)
PT (1) PT733378E (en)

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EP0733378A2 (en) 1996-09-25
DK0733378T3 (en) 2003-07-28
DE69628072D1 (en) 2003-06-18
PT733378E (en) 2003-09-30
NO961174D0 (en) 1996-03-22
NO961174L (en) 1996-09-25
US5674394A (en) 1997-10-07
ES2197935T3 (en) 2004-01-16
NO313737B1 (en) 2002-11-25
ATE240132T1 (en) 2003-05-15
US6197194B1 (en) 2001-03-06
CA2172350C (en) 2006-10-31
JP4173205B2 (en) 2008-10-29
EP0733378A3 (en) 1997-09-10
US6001259A (en) 1999-12-14
DE69628072T2 (en) 2004-04-01
US5935437A (en) 1999-08-10
MX9601089A (en) 1997-02-01
JPH08301775A (en) 1996-11-19

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