CA2192818A1 - Antiseptic dentifrice comprising essential oils - Google Patents
Antiseptic dentifrice comprising essential oilsInfo
- Publication number
- CA2192818A1 CA2192818A1 CA002192818A CA2192818A CA2192818A1 CA 2192818 A1 CA2192818 A1 CA 2192818A1 CA 002192818 A CA002192818 A CA 002192818A CA 2192818 A CA2192818 A CA 2192818A CA 2192818 A1 CA2192818 A1 CA 2192818A1
- Authority
- CA
- Canada
- Prior art keywords
- amount
- dentifrice composition
- concentration
- stable acidic
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
Abstract
An improved stable acidic antiseptic dentifrice composition with therapeutically effective amounts of essential oils formulated at a pH of between 3.0 and 5.5 is disclosed. Also disclosed is an improved stable acidic antiseptic and anticaries dentifrice composition with essential oils and one or more fluorine-releasing compounds, formulated at a pH of between 3.0 and 5.5.
Claims (19)
1. An improved stable acidic antiseptic dentifrice composition comprising an antiseptically effective amount of one or more flavor oils, said composition being buffered to a pH range of from about 3.0 to about 5.5.
2. The improved stable acidic antiseptic dentifrice composition of claim 1 wherein the concentration by weight of said flavor oils is in an amount of from about 0.1% w/w to about 4.0% w/w.
3. The improved stable acidic antiseptic dentifrice composition of claim 2 wherein the concentration by weight of said flavor oils is in an amount of from about 0.5% w/w to about 3.0% w/w.
4. The improved stable acidic antiseptic dentifrice composition of claim 3 wherein the concentration by weight of said flavor oils is in an amount of from about 1.0% w/w to about 2.0% w/w.
5. The improved stable acidic antiseptic dentifrice composition of claim 1 wherein said flavor oils are selected from the group consisting of thymol, methyl salicylate, menthol, eucalyptol, spearmint oil, cinnamon oil, clove oil, rosemary oil, and peppermint oil.
6. The improved stable acidic antiseptic dentifrice composition of claim 5 wherein said essential flavor oils consist of thymol, menthol, methyl salicylate and eucalyptol.
7. The improved stable acidic antiseptic dentifrice composition of claim 6 wherein the concentration by weight of thymol is in an amount of from about 0.01% w/w to about 1.0% w/w; the concentration by weight of menthol is in an amount of from about 0.01% w/w to about 1.0% w/w; the concentration by weight of eucalyptol is in an amount of from about 0.01% w/w to about 1.0% w/w; and the concentration of methyl salicylate is in an amount of from about 0.01% w/w to about 1.0% w/w.
8. The improved stable acidic antiseptic dentifrice composition of claim 7 where the concentration by weight of thymol is in an amount of from about 0.1% w/w to about 0.6% w/w; the concentration by weight of menthol is in an amount of from about 0.1% w/w to about 0.7% w/w; the concentration by weight of eucalyptol is in an amount of from about 0.05% w/w to about 0.5% w/w; and the concentration of methyl salicylate is in an amount of from about 0.04% w/w to about 0.6% w/w.
9. The improved stable acidic antiseptic dentifrice composition of claim 8 wherein the concentration by weight of thymol is in an amount of from about 0.2% w/w to about 0.5% w/w; the concentration by weight of menthol is in an amount of from about 0.1% w/w to about 0.6% w/w; the concentration by weight of eucalyptol is in an amount of from about 0.07% w/w to about 0.4% w/w; and the concentration of methyl salicylate is in an amount of from about 0.1% w/w to about 0.6% w.w.
10. The improved stable acidic antiseptic dentifrice composition of claim 1 further comprising one or more fluoride-releasing compounds.
11. The improved stable acidic antiseptic dentifrice composition of claim 10 wherein said fluoride-releasing compound is selected from the group consisting of monofluophosphate, alkali metal fluoride, stannous fluoride, aluminum monofluorophosphate, aluminum difluorophosphate, and mixtures thereof.
12. The improved stable acidic antiseptic dentifrice composition of claim 11 wherein said flavor oils are selected from the group consisting of thymol, methyl salicylate, menthol, eucalyptol, spearmint oil, cinnamon oil, clove oil, rosemary oil, and peppermint oil.
13. The improved stable acidic antiseptic dentifrice composition of claim 12 wherein said flavor oils are thymol, menthol, methyl salicylate, and eucalyptol.
14. The improved stable acidic antiseptic dentifrice composition of claim 11 wherein said fluoride-releasing compound is sodium monofluorophosphate.
15. The improved stable acidic antiseptic dentifrice composition of claim 14 wherein the concentration by weight of said sodium monofluorophosphate is in an amount of from about 0.5% w/w to about 1.0% w/w.
16. The improved stable acidic antiseptic dentifrice composition of claim 1 or claim 10 further comprising one or more dentifrice additives.
17. A method for preparing a stable acidic antiseptic dentifrice composition comprising:
a) admixing water, humectant, sweetener, phosphate salts and benzoic acid to form a first mixture;
b) admixing humectant with gum to form a second mixture;
c) admixing said first and second mixture to form a third mixture;
d) admixing titanium dioxide and silicas to form a fourth mixture;
e) admixing said third and fourth mixtures to form a fifth mixture;
f) admixing said fifth mixture with colors, flavors, and surfactants to form a sixth mixture;
g) adjusting the pH of said sixth mixture to a pH of from about 3.5 to 5.5 with acidifiers;
h) dearating said sixth mixture under a vacuum.
a) admixing water, humectant, sweetener, phosphate salts and benzoic acid to form a first mixture;
b) admixing humectant with gum to form a second mixture;
c) admixing said first and second mixture to form a third mixture;
d) admixing titanium dioxide and silicas to form a fourth mixture;
e) admixing said third and fourth mixtures to form a fifth mixture;
f) admixing said fifth mixture with colors, flavors, and surfactants to form a sixth mixture;
g) adjusting the pH of said sixth mixture to a pH of from about 3.5 to 5.5 with acidifiers;
h) dearating said sixth mixture under a vacuum.
18. The method of claim 17 for preparing a stable acidic antiseptic dentifrice composition further comprising admixing one or more fluoride-releasing compounds during the formation of the first mixture.
19. The method of claim 17 further comprising adding one or more fluoride-releasing compounds in step (a) of said method.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28009894A | 1994-07-25 | 1994-07-25 | |
| US280,098 | 1994-07-25 | ||
| PCT/US1995/006249 WO1996003109A1 (en) | 1994-07-25 | 1995-06-06 | Antiseptic dentifrice |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2192818A1 true CA2192818A1 (en) | 1996-02-08 |
| CA2192818C CA2192818C (en) | 2011-04-05 |
Family
ID=23071667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2192818A Expired - Lifetime CA2192818C (en) | 1994-07-25 | 1995-06-06 | Antiseptic dentifrice comprising essential oils |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5942211A (en) |
| EP (1) | EP0767654B1 (en) |
| JP (1) | JP3721539B2 (en) |
| CN (1) | CN1107493C (en) |
| AT (1) | ATE229314T1 (en) |
| AU (1) | AU698788B2 (en) |
| CA (1) | CA2192818C (en) |
| DE (1) | DE69529160T2 (en) |
| DK (1) | DK0767654T3 (en) |
| EG (1) | EG21210A (en) |
| ES (1) | ES2187560T3 (en) |
| GT (1) | GT199500037A (en) |
| HR (1) | HRP950385A2 (en) |
| IL (1) | IL114035A (en) |
| MX (1) | MX9606603A (en) |
| NZ (1) | NZ288002A (en) |
| PE (1) | PE43996A1 (en) |
| PT (1) | PT767654E (en) |
| SI (1) | SI0767654T1 (en) |
| SV (1) | SV1995000043A (en) |
| UY (1) | UY24005A1 (en) |
| WO (1) | WO1996003109A1 (en) |
| ZA (1) | ZA956147B (en) |
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| WO1997015277A1 (en) * | 1995-10-23 | 1997-05-01 | Warner-Lambert Company | Enhanced stannous oral composition |
| TR199801528T2 (en) * | 1996-02-08 | 1998-11-23 | Warner-Lambert Company | Dental cleaning composition containing highly soluble pyrophosphate, effective against calculus. |
| DE19730651A1 (en) * | 1997-07-17 | 1999-01-21 | Henkel Kgaa | Oral and dental care products for sensitive teeth |
| MY119059A (en) † | 1997-08-11 | 2005-03-31 | Cadbury Adams Usa Llc | Enhanced flavoring compositions containing n-ethyl-p-menthane-3-carboxamide and method of making and using same |
| WO1999032075A1 (en) * | 1997-12-22 | 1999-07-01 | Warner-Lambert Company | Compositions for inhibiting gingivitis |
| US7588793B1 (en) | 1998-06-05 | 2009-09-15 | Cadbury Adams Usa, Llc | Enhanced flavoring compositions containing N-ethyl-p-menthane-3-carboxamide and method of making and using same |
| JP2001303934A (en) * | 1998-06-23 | 2001-10-31 | Toyota Motor Corp | Exhaust emission control device for internal combustion engine |
| US6861048B2 (en) | 1999-04-08 | 2005-03-01 | Warner-Lambert Company | Dentifrice compositions having reduced abrasivity |
| US6221340B1 (en) * | 1999-04-08 | 2001-04-24 | Warner-Lambert Company | Zinc containing dentifrice compositions |
| US6123926A (en) * | 1999-04-13 | 2000-09-26 | Warner-Lambert Company | Silica containing dentifrice compositions |
| US6610276B2 (en) * | 2001-01-12 | 2003-08-26 | Steven A. Melman | Multi-functional dental composition |
| JP2004535370A (en) * | 2001-03-05 | 2004-11-25 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | Liquid pharmaceutical composition with masked taste |
| JP2004018470A (en) * | 2002-06-18 | 2004-01-22 | Takasago Internatl Corp | Antimicrobial perfume composition, foul breath-preventing perfume composition, and composition for oral cavity containing the compositions |
| US6880350B2 (en) * | 2002-09-13 | 2005-04-19 | Isothermal Systems Research, Inc. | Dynamic spray system |
| US6689343B1 (en) * | 2002-11-05 | 2004-02-10 | Ultradent Products, Inc. | Hemostatic and acid etch compositions containing sucralose |
| GB0303677D0 (en) * | 2003-02-18 | 2003-03-19 | Quest Int | Flavoured products |
| US8597703B2 (en) | 2005-05-23 | 2013-12-03 | Kraft Foods Global Brands Llc | Delivery system for active components as part of an edible composition including a ratio of encapsulating material and active component |
| US8591973B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for active components and a material having preselected hydrophobicity as part of an edible composition |
| US8591972B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for coated active components as part of an edible composition |
| US8389032B2 (en) | 2005-05-23 | 2013-03-05 | Kraft Foods Global Brands Llc | Delivery system for active components as part of an edible composition having selected particle size |
| US20050112236A1 (en) | 2003-11-21 | 2005-05-26 | Navroz Boghani | Delivery system for active components as part of an edible composition having preselected tensile strength |
| US8591974B2 (en) * | 2003-11-21 | 2013-11-26 | Kraft Foods Global Brands Llc | Delivery system for two or more active components as part of an edible composition |
| US8591968B2 (en) | 2005-05-23 | 2013-11-26 | Kraft Foods Global Brands Llc | Edible composition including a delivery system for active components |
| PL1786272T3 (en) | 2004-08-11 | 2015-02-27 | Intercontinental Great Brands Llc | Warming compositions and delivery systems therefor |
| US7955630B2 (en) | 2004-09-30 | 2011-06-07 | Kraft Foods Global Brands Llc | Thermally stable, high tensile strength encapsulated actives |
| DE102004043945A1 (en) * | 2004-09-11 | 2006-03-30 | Henkel Kgaa | Oral, dental and dental protease care products containing plaque-forming substances |
| US7611695B2 (en) * | 2004-11-15 | 2009-11-03 | Ultradent Products, Inc. | Flavored hemostatic and acid etching compositions |
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| US9724278B2 (en) * | 2008-06-13 | 2017-08-08 | Colgate-Palmolive Company | Oral compositions and uses thereof |
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| CN103635096B (en) | 2011-04-29 | 2016-08-17 | 洲际大品牌有限责任公司 | Encapsulated acid, its preparation method and include the chewing gum of described encapsulated acid |
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| CN107028829B (en) * | 2017-04-25 | 2020-07-21 | 攀枝花学院 | Compound mango leaf extract anti-inflammatory health-care toothpaste and preparation method thereof |
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-
1995
- 1995-06-06 AT AT95922088T patent/ATE229314T1/en not_active IP Right Cessation
- 1995-06-06 JP JP50571996A patent/JP3721539B2/en not_active Expired - Lifetime
- 1995-06-06 DE DE69529160T patent/DE69529160T2/en not_active Expired - Fee Related
- 1995-06-06 NZ NZ288002A patent/NZ288002A/en not_active IP Right Cessation
- 1995-06-06 DK DK95922088T patent/DK0767654T3/en active
- 1995-06-06 ES ES95922088T patent/ES2187560T3/en not_active Expired - Lifetime
- 1995-06-06 EP EP95922088A patent/EP0767654B1/en not_active Expired - Lifetime
- 1995-06-06 CN CN95194280A patent/CN1107493C/en not_active Expired - Fee Related
- 1995-06-06 CA CA2192818A patent/CA2192818C/en not_active Expired - Lifetime
- 1995-06-06 MX MX9606603A patent/MX9606603A/en unknown
- 1995-06-06 WO PCT/US1995/006249 patent/WO1996003109A1/en active IP Right Grant
- 1995-06-06 SI SI9530632T patent/SI0767654T1/en unknown
- 1995-06-06 AU AU26898/95A patent/AU698788B2/en not_active Expired
- 1995-06-06 PT PT95922088T patent/PT767654E/en unknown
- 1995-06-07 IL IL11403595A patent/IL114035A/en not_active IP Right Cessation
- 1995-07-07 HR HR08/280,098A patent/HRP950385A2/en not_active Application Discontinuation
- 1995-07-24 EG EG61695A patent/EG21210A/en active
- 1995-07-24 ZA ZA956147A patent/ZA956147B/en unknown
- 1995-07-24 GT GT199500037A patent/GT199500037A/en unknown
- 1995-07-24 UY UY24005A patent/UY24005A1/en unknown
- 1995-07-25 PE PE1995274698A patent/PE43996A1/en not_active Application Discontinuation
- 1995-07-25 SV SV1995000043A patent/SV1995000043A/en not_active Application Discontinuation
-
1996
- 1996-12-27 US US08/774,990 patent/US5942211A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| SI0767654T1 (en) | 2003-04-30 |
| UY24005A1 (en) | 1995-08-17 |
| ZA956147B (en) | 1996-03-07 |
| US5942211A (en) | 1999-08-24 |
| JP3721539B2 (en) | 2005-11-30 |
| EP0767654A1 (en) | 1997-04-16 |
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| DE69529160D1 (en) | 2003-01-23 |
| JPH10503196A (en) | 1998-03-24 |
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| WO1996003109A1 (en) | 1996-02-08 |
| DK0767654T3 (en) | 2003-03-24 |
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| AU698788B2 (en) | 1998-11-05 |
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| IL114035A0 (en) | 1995-10-31 |
| ES2187560T3 (en) | 2003-06-16 |
| GT199500037A (en) | 1997-01-14 |
| CA2192818C (en) | 2011-04-05 |
| NZ288002A (en) | 1998-07-28 |
| SV1995000043A (en) | 1997-02-27 |
| DE69529160T2 (en) | 2003-09-11 |
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