CA2207644C - Five beveled point geometry for a hypodermic needle - Google Patents

Five beveled point geometry for a hypodermic needle Download PDF

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Publication number
CA2207644C
CA2207644C CA002207644A CA2207644A CA2207644C CA 2207644 C CA2207644 C CA 2207644C CA 002207644 A CA002207644 A CA 002207644A CA 2207644 A CA2207644 A CA 2207644A CA 2207644 C CA2207644 C CA 2207644C
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Canada
Prior art keywords
needle
cannula
bevels
angle
central axis
Prior art date
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Expired - Lifetime
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CA002207644A
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French (fr)
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CA2207644A1 (en
Inventor
Judith L. Doyle
Steven L. Koziol
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Becton Dickinson and Co
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Becton Dickinson and Co
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Publication of CA2207644A1 publication Critical patent/CA2207644A1/en
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B24GRINDING; POLISHING
    • B24BMACHINES, DEVICES, OR PROCESSES FOR GRINDING OR POLISHING; DRESSING OR CONDITIONING OF ABRADING SURFACES; FEEDING OF GRINDING, POLISHING, OR LAPPING AGENTS
    • B24B19/00Single-purpose machines or devices for particular grinding operations not covered by any other main group
    • B24B19/16Single-purpose machines or devices for particular grinding operations not covered by any other main group for grinding sharp-pointed workpieces, e.g. needles, pens, fish hooks, tweezers or record player styli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3286Needle tip design, e.g. for improved penetration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/19Constructional features of carpules, syringes or blisters
    • A61M2205/192Avoiding coring, e.g. preventing formation of particles during puncture
    • A61M2205/195Avoiding coring, e.g. preventing formation of particles during puncture by the needle tip shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202Devices for protection of the needle before use, e.g. caps

Abstract

A hypodermic needle featuring a multi-beveled point geometry is disclosed. In one embodiment, the multi-beveled point features a primary bevel, a pair of tip bevels, and a pair of middle bevels each intermediate the primary bevel and a respective one of the tip bevels. The primary and middle bevels are provided at angles of inclination, measured between the central axis and a reference plane that are substantially identical. The tip bevels are formed at an angle of inclination respective to the central axis which is not equal to the angle of inclination at which the primary and middle bevels are formed. The resulting five-beveled point geometry contributes to a more continuous bevel face free of abrupt intercepts or transitions between the respective bevel faces, lessening the penetration force required to urge the needle point through skin, flesh, or other material.

Description

-, CA 02207644 1997-06-12 ,.

A FIV~ BEVELI~D POINT GEOMETRY FOR A ~YPODERMIC NEEDLl~

I. Field of the Invention.
The invention relates to a point geometry for a hypodermic needle, and more particularly, to a five beveled point geometry for a hypodermic needle for a reducing needle 15 penetration force LL Back~round.
A hypodermic needle is typically formed from an elongate tube or cannula having a fluid-conducting lumen and characterized by a central axis. The proximal end of the 20 hypodermic needle is typically configured for mating to, or is otherwise afflxed to, a fluid delivery device such as a hypodermic syringe The distal end of the hypodermic needle is typically provided with a pointed tip geometry for piercing elastomeric septums and/or a patient's flesh or tissue so as to deliver the medicament held in the syringe. The practitioner may also employ the hypodermic needle for aspirating fluids held in a vessel such as a vial.
25 This use often entails a practitioner inserting the pointed tip of the needle through a rubber or elastomeric-type seal associated with the vessel so that the practitioner can access the fluid contained within the vessel.
Various considerations merit address when designing the pointed tip of the hypoderrnic needle. For instance, one would like to minimi7e the needle penetration force necessarv for 30 urging the pointed tip of the needle through the skin and flesh structure of the patient. It is generally recognized that by reducing needle penetration force, the patient will experience less pain, making the injection more comfortable. Another consideration in desi~ning point geometry is to prevent or otherwise minimi7e "coring". Coring, as the skilled artisan will appreciate, results when a portion of a material through which the needle has penetrated 35 becomes lodged in the lumen adjacent the pointed tip.

(1) ' P-3~49 Certain efforts in the art have sought to address one or more of the aforementioned concerns. One approach is found in U.S. Patent No. 3,071,135 (Baldwin et al.). Here, the needle face is characterized by a pair of side facets (or "bevels"), which intersect with a main facet. The heel portion of the needle face includes an external recess which merges with a smoothly rounded surface or edge portion of the lumen opening. It is stated in this patent that the provision of the needle recess relieves tension of a membrane flap created upon entry of the needle, thereby reducing the penetration force. U.S. Patent No. 2,560,162 (Ferguson) provides a similar structure, albeit with the provision of an additional pair of forward side bevels. An emphasis of this patent is that the provision of the recess (here referred to as a depression) prevents or lllil~i, .,;,~c the severing of a plug from a layer or layers being pierced by the needle. U.S. Patent No. 3,308,822 (DeLuca) has as its objective Illi~lillli;~.;ll~ the penetration force of a needle so as to ~ iYe pain incident to an injection. This patent states to create, from an initial piercing point of the flesh, three substantially straight lines in the form of the letter "Y". It is stated that by forming the "Y" shaped cut, three sub.s~nti~lly V-shaped flaps are formed, the three angular edges of which are capable of extension into a circular form in the opening of the skin, thereby preventing extensive stretching or tensioning of the edges of the cut. The needle point employs five faces produced by a series of five grinds, with the last two grinds resulting in bevels disposed not ~ enf the opening of the needle, but rather on the back of the needle away from the opening. U.S. Patent No. 2,409,979 (Huber) relates to a hypodermic needle also intended to reduce pain as the needle penetrates the tissue. E~uber appears to describe a primary bevel mating with a pair of beveled surfaces that meet at a curved surface of ~limini~hing area adjacent the end portion of the needle.
Despite the attempts in the art to arrive at a needle point geometry to lessen needle penetration forces, there continues to exist a need for a needle point geometry which displays reduced needle penetration forces and, hence, reduces the pain or discomfort level experienced by a patient. Such a needle point geometry is disclosed herein.

III. Summarv of the Invention.
It has been surmised by the inventors herein that a primary reason that a patient experiences pain when the needle is inserted is that a portion of the needle point "catches" on the skin or flesh as the needle penetrates. It has been reasoned by the inventors herein that one cause of a needle point c~tchin~; the skin or flesh is due to the height of the "intercept"
established at the transition between differing bevels forming the needle point. It is reasoned that if the transitions between differing bevels forming the needle point were less pronounced, the height of the intercepts would be reduced The effect of reducing the heights of the o P-3549 transitions would be to approximate, ~rom a series of bevels forming the point, a more continuous, unitary bevel face. The resulting continuous bevel point would require less penetration force to enter a patient's flesh. By reducing penetration forces, it is believed that the patient may experience less pain.
S Accordingly, the invention relates to a multi-beveled needle point reducing the heights of the intercepts created between merging bevels that results in a more continuous bevel face.
The needle includes a cannula having a lumen and a central axis therethrough. The multi-beveled needle point defines an opening to the lumen for the passage of fluids between a medical delivery device and a patient or vessel. The multi-beveled needle point preferably includes a primary bevel, a pair of tip bevels and a pair of middle bevels. Each of the middle bevels are contiguous with the primary bevel and meet a respective one of the tip bevels at an intersect. The primary bevel is formed or otherwise provided on the cannula by inclining the central axis of the needle cannula to a first planar angle respective of a reference plane.
Preferably, each of the middle bevels and tip bevels is formed by rotating the cannula 1~ along the central axis within a range of rotational angles respective to the position of the primary bevel. Preferably, the middle bevels are formed on the cannula at a planar angle subst~nti~lly equal to if not identical to the first planar angle at which the primary bevel is formed. Preferably, each of the tip bevels is formed at a planar angle which is not equal to the first planar angle at which the primar,v bevel is formed. The resulting needle point, formed of five distinct bevels, displays reduced height intercepts, resulting in a more continuous bevel face about the opening. It is also surmised that by providing a series of five distinct bevels, the needle point is lengfll~ned over needle points conventionally in use, and owing to the reduced height intervals, results in an effective outer diameter at the needle point less than the outer diameter of needle points currently in use, all of which contribute to reduced needle 2~ penetration forces.

rv. Brief Dese. ;IJlion of the D~
The invention will now be described in more detail by way of with reference to the appended drawings, wherein:
Figure 1 is a frontal perspective view of a multi-beveled needle tip geometry inaccordance with the present invention;
Figure 2 is a top view of the multi-beveled needle tip of Figure l;
Figure 3 is a side view of the multi-beveled needle tip of Figure l;

' P-3~49 Figure 4 is a frontal view of the multi-beveled needle tip of Figure 1, depicting rotational angles about the central axis of the cannula for forming the middle bevels and tip bevels;
Figure S is a second side view of a multi-beveled needle tip in accordance with the 5 present invention, depicting the cannula rotated about the central axis at a first rotational angle and inclined at a first planar angle with respect to an imZlgin~y plane exten~1ing through the central axis for forming the middle bevels; and Figure 6 is a third side view of a multi-beveled needle tip in accordance with the present invention, depicting the cannula rotated at a second rotational angle about the central 10 axis of the cannula and inclined at a second planar angle with respect to an im~gin~ry plane extending through the central axis for forming the tip bevels.

V. Detailed Description of the Drawin~s.
A convention employed in this application is that the terrn "proximal" denotes adirection closest to a practitioner, while the terrn "distal" denotes a direction furthest from a practitioner.
Turning now to the drawings, wherein like numeral denote like components, Figures 1-6 depict a hypodermic needle 10 characterized by a multi-beveled point 20 in accordance with the present invention. As the skilled artisan will appreciate, hypodermic needle 10 can be forrned from a tube or c~nn~ 11 defining therein a fluid carrying duct or lumen 16.
Hypodermic needle 10 includes a proximal end 14 which can be attached in fluid communication with a medical delivery instrument (not shown). Multi-beveled point 20 defines a fluid opening 22 for passage of fluids to and from fluid carrying lumen 16. The fluid 2~ carrying lumen is characterized by a central axis 18.
Multi-beveled point 20 is characterized by a length "L" and is forrned through aplurality of individual bevels that together define a beveled face 40 about the periphery of fluid opening 22. In the embodiment disclosed by applicants herein, the multi-beveled point is characterized by a primary bevel 30; a pair of middle bevels 32a, 32b; and a pair of tip bevels 34a, 34b. E~ach of the pair of middle bevels 32a, 32b and each of the pair of tip bevels 34a, 34b are subst~nti~lly symmetrically formed on opposite sides of primary bevel 30, as will be further described hereinbelow. Adjacent middle and tip bevels 32a, 34a meet at an intersect 38a de..,a,ca~ing the respective planes at which the middle and tip bevels are formed. Adjacent middle and tip bevels 32b, 34b likewise meet at an intersect 38b. Tip bevels 34a, 34b meet at 3~ appointed apex 36 which first enters the skin of a patient (or sealing material associated with a fluid carrying vessel).

~ P-3549 Primary bevel 30, middle bevels 32a, 32b and tip bevels 34a, 34b are formed or otherwise provided on cannula 10 by inclining and/or rotating cannula 10 through a series of angles measured relative to central axis 18. In the embodiment depicted herein, and as best illustrated in Figures 4, 5 and 6, primary bevel 30 is formed or otherwise provided on hypoderrnic needle 10 by inclining central axis 18 of hypodermic needle at an angle 30Q
measured relative to a reference plane 50. The reference plane 50 can represent, for instance, a grinding wheel which, as the skilled artisan will appreciàte, is one way to form bevels on a hypodermic needle. For purposes of explaining the formation of the middle bevels and the tip bevels, the location of primary bevel 30 on the hypodermic needle can be established by a midline rotational position 60 (see Figure 4) about central axis 18.
Middle bevels 32a, 32b and tip bevels 34a, 34b can likewise be formed or otherwise provided on hypodermic needle 10 by inclining the central axis of hypodermic needle 10 at some angle relative to reference plane 50, as well as by rotating hypodermic needle 10 about the central axis at some angle relative to mid-line rotational position 60 of primary bevel 30. In the embodiment depicted herein, each of middle bevels 32a, 32b are formed or otherwise provided on hypodermic needle 10 by inclining central axis 18 ofthe hypodermic needle at an angle 32Q relative to the reference plane 50, and by rotating the hypodermic needle about central axis 18 at a rotational angle 32~ Simllarly, tip bevels 34a,34b are formed or otherwise provided on hypodermic needle 10 by inclining the central axis 18 of hypodermic needle 10 at an angle 34Q relative to reference plane 50, and by rotating the hypodermic needle about central axis 18 at a rotational angle 34~. For purposes of simplicity, Figures 4, 5 and 6 depict inclination and/or rotation of hypodermic needle 1~ so as to form, when viewing the hypodermic needle from the frontal position of Figure 4, left side middle bevel 32a and left side tip bevel 34a. However, it will be evident to the skilled artisan that formation of right-side middle bevel 32b and right-side tip bevel 34b is effected by reversing the rotation of needle 10 about central axis 18.
It has been surmised by the applicants herein that optimum results for re~ucinp~ the height of intercepts 38a, 38b is achieved by forming primary bevel 30 and each of middle bevels 32a, 32b at angles of inclination 30Q and 32Q which are substantially equal if not identical. For instance, it has been found by applicants herein that optimum results are achieved by setting both inclination angles 30Q and 32Q, respective to im~gin~ry plane 50, in a range of about 9 degrees("~") plus or minus 1~. For purposes of simplicity, the transition de~ c~ g primary bevel 30 from each of middle bevels 32a, 32b has been denoted by the numeral 31. It is surmised that by not varying the angle of inclination 32Q for the middle 3~ bevels from angle of inclination 30Q for the prima,y bevel, transition 31 demarcating primaly bevel 30 from middle bevels 32a, 32b will be more rounded and less pronounced, contrlbuting -;

to a smoother, more continuous bevel face 40. Subsequent to formation of p~ aly bevel 30, the hypodermic needle is rotated about the central axis 18 in both the clockwise and counterclockwise directions at rotational angle 32~ to form middle bevels 32a, 32b. It has been found by the applicants herein that optimum results are obtained when the range of 5 rotational angle 32~ is about 23~ plus or minus 5~.
Tip bevels 34a, 34b are likewise formed or otherwise provided on hypodermic needle 10 by inclinin~ central axis 18 of hypodermic needle 10 to an angle 34Q relative to reference plane 50, and by rotating the hypoderrnic needle about central axis 18 to an angle 34~ It has been found by the applicants herein that optimum results for reducing the height of intercepts 38a, 38b del,.alca~ g the respective middle and tip bevels results when needle cannula 10 is inclined at an angle 34Q in a range of about 15~ plus or minus 2~, and when the needle cannula is rotated to an angle 34~ in a ran~e measuring about 23~ plus or minus 5~.
Figure 3 exemplifies the side profile of multi-beveled needle tip 20 formed in accordance with the present invention. Intercept 38a is reduced in height to an extent that 15 when viewed from the side, middle bevel 32a and tip bevel 34a appear to provide a substantially-straight profile. The same effect can be seen in Figure 6, where middle and tip bevels 32b, 34b, when viewed in side profile, define an angle "~" that is nearly 180~ as measured about intercept 38b. The effect is a more continuous bevel face 40 free of abrupt intercepts 38a, 38b (or for that matter, transitions 31 demarcating the primary middle bevels), 20 resulting in a needle tip requiring less penetration force. By recluring the heights of intercepts 38a, 38b, the effective outer diameter of needle point 20 is reduced, helping to reduce needle penetration forces.
The hypodermic needle 10 in accordance with the present invention can be formed from conventional materials such as steel. It will be realized by the skilled artisan that medical 25 grade plastics, composites, ceramics, or like materials can be substituted. The needle can be lubricated ~,vith various conventional lubricants such as silicone oils to enhance the effects obtained by applicantls geometry. The bevels can be formed on the hypodermic needle by conventional processes such as by grinding.
~t will be evident to the skilled artisan that the bevels can be formed in any order 30 desired. In one iteration, the primary and middle bevels can be formed before the tip bevels, in that in the p.~-.ed embodiment, the primary and middle bevels are formed at substantially identical angles of inclination 30Q, 32Q, and this might contribute to greater m~nllf~ctllring efficiency. However, other m~nllf~ctllring iterations can be employed. For instance, the tip bevels can be formed prior to m~nllf~t~lring either of the middle or primary bevels. A further 35 iteration would be to form the middle bevels 32a, 32b intermediate the steps required for forming primary bevel 30 and tip bevels 34a, 34b. For instance, the central axis of the hypodermic needle can be first inclined to angle 30Q for formation of the primary bevel.
Thereafter, the central axis of the hypodermic needle can be inclined to angle 34Q, and thereafter rotated about central axis 18 to angles of rotation 34~, for forrnation of the tip bevels. Thereafter, central axis of hypoderrnic needle 10 can be re-inclined to angle 32Q, and S rotated about central axis 18 to angles 32~, for formation of the middle bevels. It will be realized by the skilled artisan that any order for forming the respective bevels for needle tip 20 that results in continuous bevel face 40 will achieve the advantages and results of the invention herein.
One particular sequence perforrned by the inventors herein has resulted in the formation of concict~nfly good needle points 20. Needle point 20 was produced on a 27 gauge needle by grinding. Central axis 18 of hypodermic needle 10 was inclined at an angle of about 14.5 degrees respective of the grinding wheel for an initial 'lhog-off" grind. Thereafter, central axis 18 of the hypodermic needle was subjected to a series of angles of inclination and rotation in order to form a pair of ~ c~.nt middle and tip bevels prior to forrnation of an opposed pair of c~nt and rniddle tip bevels, with the primary bevel formed as a last grind. In the iteration perforrned by the inventors herein, subsequent to the hog-off grind, central axis 18 of the hypodermic needle was inclined with angle 3~Q of about 9 degrees, and thereafter rotated right around central axis 18 to an angle 32~ of about 20 degrees. At this point, left-side middle bevel 32a was ground. Thereafter, m~ it,i~; the rotational position 32~ of the central axis, central axis 18 was inclined to an angle 34Q of about 14.5 degrees and left-side tip bevel 34a was ground (note that angle of rotation 34~ is the same 20 degree angle established for angle of rotation 32~). After the left side middle and tip bevels were ground, central axis 18 of the needle ~ nnul~ was repositioned to the angle of inclination 32Q of about 9 degrees, and rotated 40 degrees to the left of the position where the left side middle and tip 2~ bevels had been ground. At this point, right middle bevel 32b was ground. Thereafter, ing central axis 18 of the needle in its rotational position, the central axis was inclined to an angle of inclination 34Q of about 14.~ degrees and tip bevel 34b was ground.
Thereafter, central axis 18 of the needle cannula was rotated 20 degrees back to its center position, the central axis 18 positioned at an angle of inclination 30Q of about 9 degrees, and primary bevel 30 was ground.
Tests were conducted comparing penetration force in rubber vial stoppers (20 millimeter rubber vial stoppers, model number 88-29530, m~nuf~ctllred by Abbott Laboratories of Ashland, Ohio) of 26 gauge needles produced in accordance with the above-identified steps against penetration forces exhibited by existing 26 gauge needles currently 3~ employed in HYPAK~Lbrand prefillable syringes, m~nuf~ctllred by Becton Dickinson Pharm~ceutical Systems of Le Pont de Claix, France. Each of the needles were lubed with ~ P-3549 -polydimethylsiloxane. Various angles of rotation 32i~, 34~ and angles of inclination 30Q, 32Q
and 34Q were tested. The resulting table illustrates that 26 gauge needles displaying needle point 20 according to the invention had significantly reduced needle penetration forces as compared to existing product:
s TABLl~ I

26G S-Bevel Needles All needles lubed with polydimethylsiloxane Rubber Vial Penetration Forces in Gram Force (Average ~IYPAK Brand Needle Control Force= 468.5gmf~
An~le ~f Rotat on An~le ~~f Inclina~ion 32~ 34~ 30Q, 32Q 34Q Point Len~th ("L") .094 Point Len~th .0~0"
Tip Bevel Length .036" Tip Bevel Length .040"
3~~ 35~ 10~ 10~ 341 ~ gm.f 30~ 30~ 10~ 10~ 338.1 gm.f 22~ 22~ 10~ 16~ 344.5 gm.f 22~ 22~ 13~ 16~ 359.0gm.f The formation of a multi-beveled tip as described herein results in a bevel face 40 which is more continuous, free of abrupt h~Lelcepts or transitions. Absent abrupt intercepts or transitions, the likelihood that a portion of the bevel face will catch the skin or flesh or a patient is reduced, and the effective outside diameter of the needle point will be reduced, all meaning that needle penetration forces will be lessened.
It will be appreciated and understood by those skilled in the art that further and additional forms of the invention may be devised without departing from the spirit and scope of the appended claims, the invention not being limited to the specific embodiments shown.

Claims (15)

1. A needle having a multi-beveled point, comprising:
a cannula having a lumen and a central axis therethrough, said multi-beveled point provided at one end of the cannula, said multi-beveled point comprised of a primary bevel, a pair of tip bevels, and a pair of middle bevels, each of said pair of middle bevels intermediate said primary bevel and one of said pair of tip bevels, wherein each of said pair of tip bevels meets a respective middle bevel at an intersection line, wherein respective of angles defined between said central axis and a reference plane, said primary bevel is provided on said cannula at a first planar angle, said pair of middle bevels are provided on said cannula at a second planar angle, and said pair of tip bevels are provided on said cannula at a third planar angle, and wherein respective of an angle of rotation about said central axis, said primary bevel is provided at a first rotational angle, said pair of middle bevels are each provided at a second rotational angle, and said pair of tip bevels are each provided at a third rotational angle, wherein said first and second planar angles are substantially equal.
2. The needle of Claim 1, wherein said first and second planar angles are in the range of 9 degrees plus or minus 1 degree.
3. The needle of Claim 1, wherein said third planar angle is in the range of degrees plus or minus 2 degrees.
4. The needle of Claim 1, wherein said second rotational angle is in the range of 18.5 degrees plus or minus 5 degrees.
5. The needle of Claim 1, wherein said third rotational angle is in the range of 23 degrees plus or minus 5 degrees.
6. The needle of Claim 1 wherein said second and third rotational angles are degrees.
7. The needle of Claim 1, wherein said cannula is formed from a metallic material.
8. A method for forming a needle having a multi-beveled point, said needle having a cannula with a lumen and a central axis therethrough, said multi-beveled point provided at one end of the cannula, comprising the following steps:
9 positioning said cannula at a first planar angle measured between said central axis and a reference plane;
forming a primary bevel at said first planar angle, said primary bevel positioned at a first rotational angle respective of the central axis;
rotating said cannula in a first direction about said central axis to a second rotational angle respective of the first rotational angle of said primary bevel;
forming a first middle bevel at said second rotational angle;
rotating said cannula about said central axis, in a second direction opposite to said first direction, to a third rotational angle respective of said first rotational angle, said third rotational angle substantially equal to said second rotational angle;
forming a second middle bevel at said third rotational angle;
positioning said cannula at a second planar angle measured between said central axis and said reference plane;
rotating said cannula in said first direction about said central axis to a fourth rotational angle respective of the first rotational angle of said primary bevel;
forming a first tip bevel at said fourth rotational angle;
rotating said cannula about said central axis in said second direction to a fifth rotational angle respective of the first rotational angle of said primary bevel, said fifth rotational angle substantially equal to said fourth rotational angle; and forming a second tip bevel at said fifth rotational angle.
9. The method of Claim 8, wherein said steps of forming said first and second middle bevels are performed before the steps of forming said first and second tip bevels.
10. The method of Claim 8, wherein said steps of forming said first and second tip bevels are performed before the steps of forming said first and second middle bevels.
11. A method for forming a needle having a multi-beveled point, said needle having a cannula with a lumen and a central axis therethrough, said multi-beveled point provided at one end of the cannula, comprising the following steps:
positioning said cannula at a first planar angle measured between said central axis and a reference plane to establish a starting position;
rotating said cannula, while at said first planar angle, in a first direction about said central axis to a first rotational angle;
forming a first middle bevel;

positioning said cannula, while in said first rotational angle, at a second planar angle measured between said central axis and said reference plane;
forming a first tip bevel;
positioning said cannula at said first planar angle;
rotating said cannula about said central axis, in a second direction opposite to said first direction, to a second rotational angle substantially equal to said first rotational angle;
forming a second middle bevel;
positioning said cannula, while in said second rotational angle, to said second planar angle;
forming a second tip bevel;
rotating said cannula in said first direction about said central axis to said starting position; and forming a primary bevel.
12. The method of Claim 11, wherein said first planar angle is about 9 degrees.
13. The method of Claim 11, wherein said second planar angle is about 14.5 degrees.
14. The method of Claim 11, wherein said first rotational angle is about 20 degrees.
15. The method of Claim 11, wherein said second rotational angle is about 20 degrees.
CA002207644A 1996-06-20 1997-06-12 Five beveled point geometry for a hypodermic needle Expired - Lifetime CA2207644C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/670,255 US5752942A (en) 1996-06-20 1996-06-20 Five beveled point geometry for a hypodermic needle
US08/670,255 1996-06-20

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CA2207644A1 CA2207644A1 (en) 1997-12-20
CA2207644C true CA2207644C (en) 2000-11-28

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Families Citing this family (119)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5752942A (en) * 1996-06-20 1998-05-19 Becton Dickinson And Company Five beveled point geometry for a hypodermic needle
US7468055B2 (en) * 1996-06-20 2008-12-23 Becton Dickinson And Company Multi-beveled point needle and syringe having a multi-beveled point needle
US6629963B2 (en) * 1996-06-20 2003-10-07 Becton, Dickinson And Company Syringe and needle shield assembly and method of sterilizing such assembly
MY128127A (en) * 1998-04-23 2007-01-31 Alza Corp Trocar for inserting implants
US7063681B1 (en) 1998-04-23 2006-06-20 Alza Corporation Trocar for inserting implants
GB9817662D0 (en) 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
JP3492543B2 (en) * 1999-03-15 2004-02-03 金子工業有限会社 Injection needle and its manufacturing method
DE19962421C1 (en) * 1999-12-22 2001-06-07 Roland Man Druckmasch Printing press cylinder has a bearing bush and a center sleeve at the bearing which can be coupled to the end side of the cylinder and released for a rapid cylinder change
US7070583B1 (en) 2000-07-03 2006-07-04 Dr. Japan Co., Ltd. Medical bevel needle
JP3310270B1 (en) * 2001-03-28 2002-08-05 宮子 鎌田 Medical injection needle and method of manufacturing the same
US20030069550A1 (en) * 2001-10-06 2003-04-10 Sharp M. Keith Hypodermic needle
DE10207770B4 (en) * 2002-02-23 2014-03-13 Nipro Glass Germany AG Cannula with facet cut
US8562583B2 (en) 2002-03-26 2013-10-22 Carmel Pharma Ab Method and assembly for fluid transfer and drug containment in an infusion system
JP4025567B2 (en) * 2002-03-29 2007-12-19 テルモ株式会社 Needle
US7867215B2 (en) * 2002-04-17 2011-01-11 Carmel Pharma Ab Method and device for fluid transfer in an infusion system
US20050096594A1 (en) * 2002-04-30 2005-05-05 Doctor's Research Group, Incorporated Cannula arrangements
SE523001C2 (en) * 2002-07-09 2004-03-23 Carmel Pharma Ab Coupling component for transmitting medical substances, comprises connecting mechanism for releasable connection to second coupling component having further channel for creating coupling, where connecting mechanism is thread
EP1549228A4 (en) 2002-07-17 2010-04-07 Tyco Healthcare Surgical se suture needle
US6702790B1 (en) * 2002-10-31 2004-03-09 Chauncey F. Ross Hypodermic needle
EP1590024B1 (en) * 2003-01-21 2016-04-27 Carmel Pharma AB A needle for penetrating a membrane
US20040143218A1 (en) * 2003-01-21 2004-07-22 Animas Corporation Needle having optimum grind for reduced insertion force
EP1532996A1 (en) 2003-11-20 2005-05-25 Novo Nordisk A/S Non grinded needle tip-geometry for an injection needle
US7361182B2 (en) * 2003-12-19 2008-04-22 Lightnix, Inc. Medical lancet
KR100672875B1 (en) * 2004-06-08 2007-01-24 안강 Medical needle
RU2007106069A (en) * 2004-07-20 2008-08-27 БАЙЕР ХЕЛТКЭР ЭлЭлСи (US) Lancet with several tips
JP4826711B2 (en) * 2005-03-31 2011-11-30 ニプロ株式会社 Needle
US20070123935A1 (en) * 2005-11-30 2007-05-31 Myers Gene E Method and apparatus for contemporaneous formation of a body structure opening and homologous pedicle
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US7942860B2 (en) 2007-03-16 2011-05-17 Carmel Pharma Ab Piercing member protection device
US7975733B2 (en) 2007-05-08 2011-07-12 Carmel Pharma Ab Fluid transfer device
US8622985B2 (en) * 2007-06-13 2014-01-07 Carmel Pharma Ab Arrangement for use with a medical device
US8029747B2 (en) 2007-06-13 2011-10-04 Carmel Pharma Ab Pressure equalizing device, receptacle and method
US8657803B2 (en) 2007-06-13 2014-02-25 Carmel Pharma Ab Device for providing fluid to a receptacle
US20090030381A1 (en) * 2007-07-23 2009-01-29 Lind Casey J Arced Hypodermic Needle
US10398834B2 (en) 2007-08-30 2019-09-03 Carmel Pharma Ab Device, sealing member and fluid container
US8287513B2 (en) 2007-09-11 2012-10-16 Carmel Pharma Ab Piercing member protection device
JP5329546B2 (en) 2007-09-17 2013-10-30 カルメル ファルマ アクチボラゲット Bag connector
US8075550B2 (en) * 2008-07-01 2011-12-13 Carmel Pharma Ab Piercing member protection device
JP5215394B2 (en) * 2008-07-15 2013-06-19 佐藤製薬株式会社 Otolaryngological needle
CN101357246B (en) * 2008-09-24 2011-11-16 杨昌燕 Safe medical needle head and processing method thereof
US8790330B2 (en) * 2008-12-15 2014-07-29 Carmel Pharma Ab Connection arrangement and method for connecting a medical device to the improved connection arrangement
US8523838B2 (en) * 2008-12-15 2013-09-03 Carmel Pharma Ab Connector device
EP2260764A1 (en) * 2009-06-10 2010-12-15 F. Hoffmann-La Roche AG Microneedle and method for its manufacture
USD637713S1 (en) 2009-11-20 2011-05-10 Carmel Pharma Ab Medical device adaptor
US8480646B2 (en) * 2009-11-20 2013-07-09 Carmel Pharma Ab Medical device connector
US9168203B2 (en) 2010-05-21 2015-10-27 Carmel Pharma Ab Connectors for fluid containers
US8162013B2 (en) 2010-05-21 2012-04-24 Tobias Rosenquist Connectors for fluid containers
WO2012044952A2 (en) * 2010-09-30 2012-04-05 Surmodics, Inc. Drug delivery blade and methods for delivering a drug depot to a target site
JP5704389B2 (en) 2010-11-29 2015-04-22 ニプロ株式会社 Medical hollow needle and method for producing medical hollow needle
US20130274768A1 (en) 2012-02-29 2013-10-17 Marker Medical, Llc Surgical apparatus and method
ES2596519T3 (en) * 2012-07-13 2017-01-10 Becton, Dickinson And Company Ltd. Access device to a medical vial with pressure equalization system and closed medication transfer and method of use thereof
IL221634A0 (en) 2012-08-26 2012-12-31 Medimop Medical Projects Ltd Universal drug vial adapter
WO2014036009A1 (en) * 2012-08-27 2014-03-06 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using microneedles
IL225734A0 (en) 2013-04-14 2013-09-30 Medimop Medical Projects Ltd Ready-to-use drug vial assemblages including drug vial and drug vial closure having fluid transfer member, and drug vial closure therefor
WO2014179698A2 (en) 2013-05-03 2014-11-06 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
BR112015027555B1 (en) 2013-05-10 2022-02-01 Medimop Medical Projects Ltd Medical device for use with a needleless syringe, a vial and a liquid carrier to fill the needleless syringe with an injection solution for injection into a patient
US10099043B2 (en) 2013-07-16 2018-10-16 3M Innovative Properties Company Hollow microneedle array article
JP6430501B2 (en) 2013-07-16 2018-11-28 スリーエム イノベイティブ プロパティズ カンパニー Hollow microneedle with beveled opening
US10232157B2 (en) 2013-07-16 2019-03-19 3M Innovative Properties Company Hollow microneedle with beveled tip
CN105407957A (en) 2013-07-16 2016-03-16 3M创新有限公司 Article comprising a microneedle
JP3205560U (en) 2013-08-07 2016-08-04 メディモップ・メディカル・プロジェクツ・リミテッド Liquid transfer device for use with a drip liquid container
CN105939740B (en) * 2014-01-31 2019-11-01 泰尔茂株式会社 The manufacturing method of therapeutic medical puncture needle and puncture needle
PL3110349T3 (en) * 2014-02-26 2018-09-28 F. Hoffmann-La Roche Ag An implant needle and method for production
USD794183S1 (en) * 2014-03-19 2017-08-08 Medimop Medical Projects Ltd. Dual ended liquid transfer spike
JPWO2016006342A1 (en) * 2014-07-08 2017-04-27 テルモ株式会社 Needle
US20160030014A1 (en) 2014-07-30 2016-02-04 Covidien Lp Exchangeable core biopsy needle
US10159470B2 (en) 2014-07-30 2018-12-25 Covidien Lp Exchangeable core biopsy needle
US10182798B2 (en) 2014-07-30 2019-01-22 Covidien Lp Exchangeable core biopsy needle
WO2016084046A1 (en) * 2014-11-28 2016-06-02 Med Italia Biomedica S.R.L. Syringe and relative needle
US11793942B2 (en) * 2014-12-11 2023-10-24 Facet Technologies, Llc Needle with multi-bevel tip geometry
US10285907B2 (en) 2015-01-05 2019-05-14 West Pharma. Services IL, Ltd. Dual vial adapter assemblages with quick release drug vial adapter for ensuring correct usage
US9844362B2 (en) 2015-01-13 2017-12-19 Covidien Lp Exchangeable core biopsy needle
EP3260050B1 (en) * 2015-02-19 2020-01-15 Olympus Corporation Biopsy needle
CN106267450A (en) * 2015-05-19 2017-01-04 广东龙心医疗器械有限公司 Many blade surfaces backcut type needle tubing
US10076352B2 (en) 2015-05-29 2018-09-18 Restoration Robotics, Inc. Implantation needle
US11147540B2 (en) * 2015-07-01 2021-10-19 Minnetronix, Inc. Introducer sheath and puncture tool for the introduction and placement of a catheter in tissue
US10357429B2 (en) 2015-07-16 2019-07-23 West Pharma. Services IL, Ltd. Liquid drug transfer devices for secure telescopic snap fit on injection vials
EP3363482A4 (en) * 2015-07-30 2019-07-24 Terumo Kabushiki Kaisha Medical puncture needle and method for producing puncture needle
WO2017017936A1 (en) * 2015-07-30 2017-02-02 テルモ株式会社 Medical puncture needle and method for producing puncture needle
RU2695505C1 (en) * 2015-09-24 2019-07-23 Бектон, Дикинсон Энд Компани Needle for use with a device for sampling and/or transfer of blood or other fluids and devices containing such a needle
KR20180082484A (en) * 2015-11-04 2018-07-18 커스텀 메디컬 애플리케이션즈, 아이엔씨. Needle and related assemblies and methods
USD801522S1 (en) 2015-11-09 2017-10-31 Medimop Medical Projects Ltd. Fluid transfer assembly
EP3380058B1 (en) 2015-11-25 2020-01-08 West Pharma Services IL, Ltd. Dual vial adapter assemblage including drug vial adapter with self-sealing access valve
US20170252520A1 (en) * 2016-03-02 2017-09-07 Nipro Corporation Puncture needle
EP3437677B1 (en) * 2016-03-28 2021-07-14 Terumo Kabushiki Kaisha Medical puncture needle and method for manufacturing puncture needle
EP3452165A1 (en) 2016-05-02 2019-03-13 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
IL245800A0 (en) 2016-05-24 2016-08-31 West Pharma Services Il Ltd Dual vial adapter assemblages including identical twin vial adapters
IL245803A0 (en) 2016-05-24 2016-08-31 West Pharma Services Il Ltd Dual vial adapter assemblages including vented drug vial adapter and vented liquid vial adapter
IL246073A0 (en) 2016-06-06 2016-08-31 West Pharma Services Il Ltd Fluid transfer devices for use with drug pump cartridge having slidable driving plunger
KR101656867B1 (en) * 2016-06-17 2016-09-12 김성운 Polisher for oriental medical acupuncture needles
DE102016014445A1 (en) 2016-07-15 2018-01-18 Acti-Med Ag Needle for piercing a membrane
WO2018031913A1 (en) 2016-08-12 2018-02-15 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery
IL247376A0 (en) 2016-08-21 2016-12-29 Medimop Medical Projects Ltd Syringe assembly
EP3506863A4 (en) * 2016-09-02 2020-04-29 Envisia Therapeutics Inc. Implant applicators
USD832430S1 (en) 2016-11-15 2018-10-30 West Pharma. Services IL, Ltd. Dual vial adapter assemblage
IL249408A0 (en) 2016-12-06 2017-03-30 Medimop Medical Projects Ltd Liquid transfer device for use with infusion liquid container and pincers-like hand tool for use therewith for releasing intact drug vial therefrom
HUE061067T2 (en) * 2017-03-14 2023-05-28 Hoffmann La Roche An implant needle
CN110785138B (en) * 2017-03-28 2023-06-23 斯贝洛克斯公司 Nasal delivery vehicles, systems, and methods of use
IL251458A0 (en) 2017-03-29 2017-06-29 Medimop Medical Projects Ltd User actuated liquid drug transfer devices for use in ready-to-use (rtu) liquid drug transfer assemblages
CN109549690B (en) * 2017-09-27 2023-08-22 泰尔茂株式会社 medical puncture needle
JP7034024B2 (en) * 2017-09-27 2022-03-11 テルモ株式会社 Medical puncture needle
IL254802A0 (en) 2017-09-29 2017-12-31 Medimop Medical Projects Ltd Dual vial adapter assemblages with twin vented female vial adapters
WO2019159525A1 (en) * 2018-02-14 2019-08-22 テルモ株式会社 Puncture needle
USD885572S1 (en) 2018-03-12 2020-05-26 Olympus Corporation Biopsy needle
TWI734958B (en) 2018-03-19 2021-08-01 日商泰爾茂股份有限公司 Puncture needle and catheter assembly
JP1630477S (en) 2018-07-06 2019-05-07
WO2020126268A1 (en) * 2018-12-17 2020-06-25 Shl Medical Ag Medical bevel needle
USD923812S1 (en) 2019-01-16 2021-06-29 West Pharma. Services IL, Ltd. Medication mixing apparatus
JP1648075S (en) 2019-01-17 2019-12-16
US11918542B2 (en) 2019-01-31 2024-03-05 West Pharma. Services IL, Ltd. Liquid transfer device
CN109806464B (en) * 2019-03-03 2021-06-04 吉林大学 Needle tip of injection needle and manufacturing method thereof
IL307176A (en) 2019-04-30 2023-11-01 West Pharma Services Il Ltd Liquid transfer device with dual lumen iv spike
CN110075395A (en) * 2019-05-22 2019-08-02 贝普医疗科技有限公司 A kind of five inclined-plane needle tubings of injection
KR20220045972A (en) 2019-12-06 2022-04-13 보스톤 싸이엔티픽 싸이메드 인코포레이티드 Endoscopic Ultrasound Guided Access Needle
KR20210073828A (en) 2019-12-11 2021-06-21 (주)풍림파마텍 six-surface cutting part with syringe needle
KR20210073825A (en) 2019-12-11 2021-06-21 (주)풍림파마텍 four-surface cutting part with syringe needle
KR20210073832A (en) 2019-12-11 2021-06-21 (주)풍림파마텍 seven-surface cutting part with syringe needle
USD956958S1 (en) 2020-07-13 2022-07-05 West Pharma. Services IL, Ltd. Liquid transfer device
CN116586924B (en) * 2023-07-17 2024-02-27 浙江一益医疗器械有限公司 Stainless steel needle tube with needle tip five-inclined-plane structure and preparation process thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2409979A (en) * 1946-03-14 1946-10-22 Ralph L Huber Hypodermic needle
US2560162A (en) * 1950-02-10 1951-07-10 Becton Dickinson Co Needle structure
US3071135A (en) * 1960-01-27 1963-01-01 Mfg Process Lab Inc Hollow needle
US3308822A (en) * 1964-04-02 1967-03-14 Loretta Fontano Hypodermic needle
DE2005519A1 (en) * 1970-02-06 1971-10-28 Roescheisen & Co Süddeutsche Bindenfabrik, 7900 Ulm Hypodermic syringe needle
US4785868A (en) * 1987-06-04 1988-11-22 Titan Medical, Inc. Medical needle and method for making
US5002564A (en) * 1989-06-19 1991-03-26 Ethicon, Inc. Surgical needle configuration with spatula geometry
US5030228A (en) * 1989-09-15 1991-07-09 Ethicon, Inc. Surgical needle configuration with five-sided cross-section
US4932961A (en) * 1989-09-15 1990-06-12 Ethicon, Inc. Surgical needle configuration with five-sided cross-section
US5002565A (en) * 1989-10-19 1991-03-26 Ethicon, Inc. Surgical needle configuration with star shaped cross-section
NL8902938A (en) * 1989-11-28 1991-06-17 Texas Instruments Holland Hollow needle with closed profile - has chamfered end with cutting edge at front and blunt stop edge
AU7594794A (en) * 1993-10-22 1995-05-11 Ethicon Inc. Surgical suture needle of the taper point type
JP3442153B2 (en) * 1994-08-23 2003-09-02 マニー株式会社 Suture Needle Mold and Suture Needle
US5575780A (en) * 1995-04-28 1996-11-19 Saito; Yoshikuni Medical hollow needle and a method of producing thereof
US5536259A (en) * 1995-07-28 1996-07-16 Medisystems Technology Corp Hypodermic cannula
US5752942A (en) * 1996-06-20 1998-05-19 Becton Dickinson And Company Five beveled point geometry for a hypodermic needle

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DE69720871D1 (en) 2003-05-22
EP0819442B1 (en) 2003-04-16
DE69734121D1 (en) 2005-10-06
CN1169320A (en) 1998-01-07
EP0819442A1 (en) 1998-01-21
EP1281411A1 (en) 2003-02-05
CA2207644A1 (en) 1997-12-20
KR100408923B1 (en) 2004-03-20
ES2247249T3 (en) 2006-03-01
DE69734121T2 (en) 2006-02-23
US5752942A (en) 1998-05-19
JP2956962B2 (en) 1999-10-04
EP1281411B1 (en) 2005-08-31
ES2195055T3 (en) 2003-12-01
US6009933A (en) 2000-01-04
SG50844A1 (en) 1998-07-20
DE69720871T2 (en) 2003-11-13
BR9703644A (en) 1998-08-11
KR980000482A (en) 1998-03-30
JPH1057490A (en) 1998-03-03
AU2490497A (en) 1998-01-08
AU738278B2 (en) 2001-09-13
CN1154519C (en) 2004-06-23
MX9704674A (en) 1997-12-31

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