CA2234019A1 - Miniature mixed gas refrigeration system - Google Patents

Miniature mixed gas refrigeration system

Info

Publication number
CA2234019A1
CA2234019A1 CA002234019A CA2234019A CA2234019A1 CA 2234019 A1 CA2234019 A1 CA 2234019A1 CA 002234019 A CA002234019 A CA 002234019A CA 2234019 A CA2234019 A CA 2234019A CA 2234019 A1 CA2234019 A1 CA 2234019A1
Authority
CA
Canada
Prior art keywords
high pressure
gas
heat exchanger
low
miniature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002234019A
Other languages
French (fr)
Other versions
CA2234019C (en
Inventor
Dobak John D., Iii
Ray Radebaugh
Marcia L. Huber
Eric D. Marquardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AMS Research LLC
US Department of Commerce
Original Assignee
Cryogen, Inc.
Secretary Of Commerce Of The United States
Dobak John D., Iii
Ray Radebaugh
Marcia L. Huber
Eric D. Marquardt
American Medical Systems Gynecology, Inc.
Ams Research Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cryogen, Inc., Secretary Of Commerce Of The United States, Dobak John D., Iii, Ray Radebaugh, Marcia L. Huber, Eric D. Marquardt, American Medical Systems Gynecology, Inc., Ams Research Corporation filed Critical Cryogen, Inc.
Publication of CA2234019A1 publication Critical patent/CA2234019A1/en
Application granted granted Critical
Publication of CA2234019C publication Critical patent/CA2234019C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28—HEAT EXCHANGE IN GENERAL
    • F28F—DETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F13/00—Arrangements for modifying heat-transfer, e.g. increasing, decreasing
    • F28F13/06—Arrangements for modifying heat-transfer, e.g. increasing, decreasing by affecting the pattern of flow of the heat-exchange media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K5/00—Heat-transfer, heat-exchange or heat-storage materials, e.g. refrigerants; Materials for the production of heat or cold by chemical reactions other than by combustion
    • C09K5/02—Materials undergoing a change of physical state when used
    • C09K5/04—Materials undergoing a change of physical state when used the change of state being from liquid to vapour or vice versa
    • C09K5/041—Materials undergoing a change of physical state when used the change of state being from liquid to vapour or vice versa for compression-type refrigeration systems
    • C09K5/044—Materials undergoing a change of physical state when used the change of state being from liquid to vapour or vice versa for compression-type refrigeration systems comprising halogenated compounds
    • C09K5/045—Materials undergoing a change of physical state when used the change of state being from liquid to vapour or vice versa for compression-type refrigeration systems comprising halogenated compounds containing only fluorine as halogen
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
    • F25B9/00—Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point
    • F25B9/002—Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point characterised by the refrigerant
    • F25B9/006—Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point characterised by the refrigerant the refrigerant containing more than one component
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
    • F25B9/00—Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point
    • F25B9/02—Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point using Joule-Thompson effect; using vortex effect
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28—HEAT EXCHANGE IN GENERAL
    • F28D—HEAT-EXCHANGE APPARATUS, NOT PROVIDED FOR IN ANOTHER SUBCLASS, IN WHICH THE HEAT-EXCHANGE MEDIA DO NOT COME INTO DIRECT CONTACT
    • F28D7/00—Heat-exchange apparatus having stationary tubular conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall
    • F28D7/10—Heat-exchange apparatus having stationary tubular conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall the conduits being arranged one within the other, e.g. concentrically
    • F28D7/12—Heat-exchange apparatus having stationary tubular conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall the conduits being arranged one within the other, e.g. concentrically the surrounding tube being closed at one end, e.g. return type
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28—HEAT EXCHANGE IN GENERAL
    • F28F—DETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F21/00—Constructions of heat-exchange apparatus characterised by the selection of particular materials
    • F28F21/08—Constructions of heat-exchange apparatus characterised by the selection of particular materials of metal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0212—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument inserted into a body lumen, e.g. catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0231—Characteristics of handpieces or probes
    • A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
    • A61B2018/0268—Characteristics of handpieces or probes using a circulating cryogenic fluid with restriction of flow
    • A61B2018/0275—Characteristics of handpieces or probes using a circulating cryogenic fluid with restriction of flow using porous elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0231—Characteristics of handpieces or probes
    • A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
    • A61B2018/0268—Characteristics of handpieces or probes using a circulating cryogenic fluid with restriction of flow
    • A61B2018/0281—Characteristics of handpieces or probes using a circulating cryogenic fluid with restriction of flow using a tortuous path, e.g. formed by fins or ribs
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2205/00—Aspects relating to compounds used in compression type refrigeration systems
    • C09K2205/10—Components
    • C09K2205/12—Hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2205/00—Aspects relating to compounds used in compression type refrigeration systems
    • C09K2205/10—Components
    • C09K2205/12—Hydrocarbons
    • C09K2205/122—Halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2205/00—Aspects relating to compounds used in compression type refrigeration systems
    • C09K2205/10—Components
    • C09K2205/13—Inert gases
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2205/00—Aspects relating to compounds used in compression type refrigeration systems
    • C09K2205/10—Components
    • C09K2205/132—Components containing nitrogen
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
    • F25B2309/00—Gas cycle refrigeration machines
    • F25B2309/003—Gas cycle refrigeration machines characterised by construction or composition of the regenerator
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
    • F25B2309/00—Gas cycle refrigeration machines
    • F25B2309/02—Gas cycle refrigeration machines using the Joule-Thompson effect
    • F25B2309/021—Gas cycle refrigeration machines using the Joule-Thompson effect with a cryosurgical probe tip having a specific construction
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
    • F25B2309/00—Gas cycle refrigeration machines
    • F25B2309/02—Gas cycle refrigeration machines using the Joule-Thompson effect
    • F25B2309/022—Gas cycle refrigeration machines using the Joule-Thompson effect characterised by the expansion element
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
    • F25B2309/00—Gas cycle refrigeration machines
    • F25B2309/02—Gas cycle refrigeration machines using the Joule-Thompson effect
    • F25B2309/023—Gas cycle refrigeration machines using the Joule-Thompson effect with two stage expansion
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
    • F25B2400/00—General features or devices for refrigeration machines, plants or systems, combined heating and refrigeration systems or heat-pump systems, i.e. not limited to a particular subgroup of F25B
    • F25B2400/12—Inflammable refrigerants
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28—HEAT EXCHANGE IN GENERAL
    • F28F—DETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F2260/00—Heat exchangers or heat exchange elements having special size, e.g. microstructures

Abstract

A miniature mixed gas refrigeration system is disclosed, having a coaxial catheter (18) with an inner high pressure supply lumen (24) and an outer low pressure return lumen (22). The gas mixture is pressurized by a compressor (12) to a pressure less than 420 psia, for safety reasons. The distal portion (23) of the outer lumen contains a micro-miniature heat exchanger (28) constructed of laminated plates or sheets (42). The plates or sheets (42) establish high pressure (36) and low pressure passageways (40), with high surface area, having a tortuous path for the gas flow to maximize heat exchange. The high pressure outlet (50) of the heat exchanger (28) is connected to a Joule-Thomson expansion element (30) where the high pressure gas is expanded isenthalpically to a lower temperature at least as low as 180K. This low temperature gas cools a heat transfer element (32) mounted in the outer wall of the catheter, to cool an external object.
Return gas flows back through the heat exchanger to pre-cool the incoming high pressure gas mixture.
CA002234019A 1995-10-12 1996-10-09 Miniature mixed gas refrigeration system Expired - Lifetime CA2234019C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/542,123 1995-10-12
US08/542,123 US6151901A (en) 1995-10-12 1995-10-12 Miniature mixed gas refrigeration system
PCT/US1996/016197 WO1997014005A1 (en) 1995-10-12 1996-10-09 Miniature mixed gas refrigeration system

Publications (2)

Publication Number Publication Date
CA2234019A1 true CA2234019A1 (en) 1997-04-17
CA2234019C CA2234019C (en) 2004-12-07

Family

ID=24162440

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002234019A Expired - Lifetime CA2234019C (en) 1995-10-12 1996-10-09 Miniature mixed gas refrigeration system

Country Status (7)

Country Link
US (1) US6151901A (en)
EP (1) EP0855010A4 (en)
JP (1) JPH11513783A (en)
AU (1) AU698470B2 (en)
CA (1) CA2234019C (en)
DE (1) DE855010T1 (en)
WO (1) WO1997014005A1 (en)

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US6051019A (en) * 1998-01-23 2000-04-18 Del Mar Medical Technologies, Inc. Selective organ hypothermia method and apparatus
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US20050228367A1 (en) * 1999-01-25 2005-10-13 Marwan Abboud Leak detection system for catheter based medical device
JP2003535615A (en) * 1999-02-12 2003-12-02 コルパン，ニコライ Cryosurgical devices, especially for the treatment of tumors
US6471694B1 (en) 2000-08-09 2002-10-29 Cryogen, Inc. Control system for cryosurgery
US7004936B2 (en) * 2000-08-09 2006-02-28 Cryocor, Inc. Refrigeration source for a cryoablation catheter
US6497703B1 (en) * 2000-03-02 2002-12-24 Biosense Webster Cryoablation catheter for long lesion ablations
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US6621071B2 (en) * 2001-09-07 2003-09-16 Raytheon Co. Microelectronic system with integral cryocooler, and its fabrication and use
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US7381208B2 (en) 2003-12-22 2008-06-03 Ams Research Corporation Cryosurgical devices for endometrial ablation
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US7727228B2 (en) 2004-03-23 2010-06-01 Medtronic Cryocath Lp Method and apparatus for inflating and deflating balloon catheters
US8491636B2 (en) 2004-03-23 2013-07-23 Medtronic Cryopath LP Method and apparatus for inflating and deflating balloon catheters
US8206345B2 (en) * 2005-03-07 2012-06-26 Medtronic Cryocath Lp Fluid control system for a medical device
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US8298220B2 (en) * 2006-11-17 2012-10-30 Coopersurgical, Inc. Cryoprobe with coaxial chambers
US8298221B2 (en) * 2006-11-17 2012-10-30 Coopersurgical, Inc. Disposable sheath with replaceable console probes for cryosurgery
WO2008099490A1 (en) * 2007-02-15 2008-08-21 Dgs Computer Medical device and medical apparatus to be used in freezing therapy
CN103423911B (en) * 2012-06-25 2015-10-28 上海理工大学 Refrigerator
US10139148B2 (en) * 2014-12-19 2018-11-27 Icejet, S.L. Methods and apparatus for cooling liquids in portable containers
CN105627609B (en) * 2015-12-30 2017-10-13 上海理工大学 Cylinder group's printed circuit board microchannel refrigerating plant
RU2713947C2 (en) * 2018-08-07 2020-02-11 Общество с ограниченной ответственностью "КРИОИНЖИНИРИНГ" Apparatus for cryotherapy
CN114562826B (en) * 2022-03-01 2023-08-29 上海理工大学 Bypass type laminated rapid precooling throttling refrigerator and control method

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Also Published As

Publication number Publication date
AU7398896A (en) 1997-04-30
EP0855010A1 (en) 1998-07-29
US6151901A (en) 2000-11-28
CA2234019C (en) 2004-12-07
JPH11513783A (en) 1999-11-24
EP0855010A4 (en) 1999-11-17
WO1997014005A1 (en) 1997-04-17
DE855010T1 (en) 1999-06-10
AU698470B2 (en) 1998-10-29

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Effective date: 20161011