CA2235183A1 - Device and apparatus for the simultaneous detection of multiple analytes - Google Patents

Device and apparatus for the simultaneous detection of multiple analytes

Info

Publication number
CA2235183A1
CA2235183A1 CA002235183A CA2235183A CA2235183A1 CA 2235183 A1 CA2235183 A1 CA 2235183A1 CA 002235183 A CA002235183 A CA 002235183A CA 2235183 A CA2235183 A CA 2235183A CA 2235183 A1 CA2235183 A1 CA 2235183A1
Authority
CA
Canada
Prior art keywords
substrate
simultaneous detection
multiple analytes
reaction sites
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002235183A
Other languages
French (fr)
Other versions
CA2235183C (en
Inventor
Stephen Peter Fitzgerald
John Victor Lamont
Robert Ivan Mcconnell
El Ouard Benchikh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Randox Laboratories Ltd
Original Assignee
Randox Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Randox Laboratories Ltd filed Critical Randox Laboratories Ltd
Publication of CA2235183A1 publication Critical patent/CA2235183A1/en
Application granted granted Critical
Publication of CA2235183C publication Critical patent/CA2235183C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/924—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Abstract

A solid state device for performing multi-analyte assays, comprises a substrate and a multiplicity of discrete reaction sites each bearing a ligand covalently bonded to the substrate, wherein the surface of the substrate between the reaction sites is inert with respect to analyte. Such a device may be obtained by a process of activating the surface of the substrate, and applying an array of ligands on to discrete areas on the surface.
CA002235183A 1997-04-21 1998-04-20 Device and apparatus for the simultaneous detection of multiple analytes Expired - Lifetime CA2235183C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97302707 1997-04-21
EP97302707.1 1997-04-21

Publications (2)

Publication Number Publication Date
CA2235183A1 true CA2235183A1 (en) 1998-10-21
CA2235183C CA2235183C (en) 2009-08-11

Family

ID=8229307

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002235183A Expired - Lifetime CA2235183C (en) 1997-04-21 1998-04-20 Device and apparatus for the simultaneous detection of multiple analytes

Country Status (32)

Country Link
US (1) US6498010B1 (en)
JP (1) JP4209494B2 (en)
KR (1) KR100585548B1 (en)
CN (1) CN1178063C (en)
AR (1) AR015110A1 (en)
AT (1) ATE289684T1 (en)
AU (1) AU713388B2 (en)
BR (1) BR9800655A (en)
CA (1) CA2235183C (en)
CZ (1) CZ297165B6 (en)
DE (1) DE69829089T3 (en)
EG (1) EG22471A (en)
ES (1) ES2238750T5 (en)
GB (1) GB2324866B (en)
GE (1) GEP20022846B (en)
HK (1) HK1012202A1 (en)
HR (1) HRP980215A2 (en)
HU (1) HU220777B1 (en)
ID (1) ID20179A (en)
MY (1) MY114814A (en)
NO (1) NO981766L (en)
NZ (1) NZ330227A (en)
PL (1) PL325914A1 (en)
PT (1) PT874242E (en)
RU (1) RU2168174C2 (en)
SG (1) SG87765A1 (en)
SK (1) SK283340B6 (en)
TR (1) TR199800737A1 (en)
TW (1) TWI225928B (en)
UA (1) UA54400C2 (en)
YU (1) YU49328B (en)
ZA (1) ZA983345B (en)

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Also Published As

Publication number Publication date
BR9800655A (en) 1999-08-10
TWI225928B (en) 2005-01-01
CN1178063C (en) 2004-12-01
CZ116998A3 (en) 1998-11-11
AU6198898A (en) 1998-10-22
MX9803102A (en) 1998-12-31
GEP20022846B (en) 2002-11-25
US6498010B1 (en) 2002-12-24
ZA983345B (en) 1999-04-21
HK1012202A1 (en) 1999-07-30
YU17498A (en) 1999-11-22
CN1215167A (en) 1999-04-28
ES2238750T3 (en) 2005-09-01
GB2324866A (en) 1998-11-04
EG22471A (en) 2003-02-26
PL325914A1 (en) 1998-10-26
SK51098A3 (en) 1998-11-04
SG87765A1 (en) 2002-04-16
PT874242E (en) 2005-06-30
MY114814A (en) 2003-01-31
HU9800920D0 (en) 1998-06-29
UA54400C2 (en) 2003-03-17
HRP980215A2 (en) 1999-02-28
NZ330227A (en) 1999-10-28
ID20179A (en) 1998-10-22
AU713388B2 (en) 1999-12-02
JPH10319011A (en) 1998-12-04
JP4209494B2 (en) 2009-01-14
RU2168174C2 (en) 2001-05-27
CA2235183C (en) 2009-08-11
GB2324866B (en) 2001-11-14
HU220777B1 (en) 2002-05-28
TR199800737A1 (en) 1998-11-23
CZ297165B6 (en) 2006-09-13
NO981766L (en) 1998-10-22
GB9808309D0 (en) 1998-06-17
KR19980081571A (en) 1998-11-25
YU49328B (en) 2005-07-19
DE69829089T2 (en) 2005-12-29
NO981766D0 (en) 1998-04-20
SK283340B6 (en) 2003-06-03
ATE289684T1 (en) 2005-03-15
DE69829089D1 (en) 2005-03-31
ES2238750T5 (en) 2009-11-03
KR100585548B1 (en) 2007-07-06
HUP9800920A1 (en) 1998-10-28
AR015110A1 (en) 2001-04-18
DE69829089T3 (en) 2009-11-26

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Effective date: 20180420