CA2252758A1 - Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries - Google Patents

Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries

Info

Publication number
CA2252758A1
CA2252758A1 CA002252758A CA2252758A CA2252758A1 CA 2252758 A1 CA2252758 A1 CA 2252758A1 CA 002252758 A CA002252758 A CA 002252758A CA 2252758 A CA2252758 A CA 2252758A CA 2252758 A1 CA2252758 A1 CA 2252758A1
Authority
CA
Canada
Prior art keywords
amniotic membrane
grafts
surgeries
preserving
separating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002252758A
Other languages
French (fr)
Other versions
CA2252758C (en
Inventor
Scheffer C. G. Tseng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TissueTech Inc
Original Assignee
Scheffer C. G. Tseng
Tissuetech, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21905738&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2252758(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Scheffer C. G. Tseng, Tissuetech, Inc filed Critical Scheffer C. G. Tseng
Publication of CA2252758A1 publication Critical patent/CA2252758A1/en
Application granted granted Critical
Publication of CA2252758C publication Critical patent/CA2252758C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/0231—Chemically defined matrices, e.g. alginate gels, for immobilising, holding or storing cells, tissue or organs for preservation purposes; Chemically altering or fixing cells, tissue or organs, e.g. by cross-linking, for preservation purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Abstract

A method for making, storing and using a surgical graft from human amniotic membrane; the resulting graft; and the storage solution.
The amniotic membrane is obtained from human placenta, from which the chorion has been separated. Sheets of the amniotic membrane are cut to size and mounted on filter paper. The cells of the amniotic membrane are killed, preferably while being frozen and thawed in the storage solution. The storage solution comprises a culture medium and a hyperosmotic agent, wherein the hydration of the amniotic membrane is maintained. The membrane can be impregnated with therapeutic agents, prior to storage, for use in post surgical healing or other therapies.
CA002252758A 1997-02-28 1998-02-25 Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries Expired - Lifetime CA2252758C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US3948697P 1997-02-28 1997-02-28
US60/039,486 1997-02-28
PCT/US1998/003665 WO1998037903A1 (en) 1997-02-28 1998-02-25 Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries
USUNKNOWN 2003-08-05

Publications (2)

Publication Number Publication Date
CA2252758A1 true CA2252758A1 (en) 1998-09-03
CA2252758C CA2252758C (en) 2008-05-13

Family

ID=21905738

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002252758A Expired - Lifetime CA2252758C (en) 1997-02-28 1998-02-25 Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries

Country Status (9)

Country Link
US (2) US6152142A (en)
EP (1) EP0918529B1 (en)
JP (1) JP2002515899A (en)
BR (1) BR9805921A (en)
CA (1) CA2252758C (en)
DE (1) DE69839437D1 (en)
ES (1) ES2307314T3 (en)
TW (1) TW398982B (en)
WO (1) WO1998037903A1 (en)

Families Citing this family (160)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4860900A (en) * 1999-06-02 2000-12-18 Lifebank Services, L.L.C. Methods of isolation, cryopreservation, and therapeutic use of human amniotic epithelial cells
ATE329632T1 (en) * 2000-04-27 2006-07-15 Tsai Ray Jui Fang METHOD FOR DEVELOPING EPITHELIAL STEM CELLS
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
CA2430989A1 (en) 2000-12-06 2002-06-13 Robert J. Hariri Method of collecting placental stem cells
AU2002230504A1 (en) 2000-12-20 2002-07-01 Alcon Universal Ltd. Ophthalmic irrigating solution adapted for use in lasik surgery
AU2002232437A1 (en) 2000-12-20 2002-07-01 Alcon Universal Ltd. Ophthalmic lubricating solution adapted for use in lasik surgery
WO2002063962A1 (en) * 2001-02-14 2002-08-22 Hariri Robert J Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
EP2316919B1 (en) * 2001-02-14 2015-10-07 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
US7347876B2 (en) * 2001-04-25 2008-03-25 Ray Jui-Fang Tsai Method for expansion of epithelial stem cells
JP3888573B2 (en) * 2001-06-29 2007-03-07 富士電機ホールディングス株式会社 Solder composition
CN100516200C (en) * 2001-11-09 2009-07-22 阿特塞尔科学公司 Adipose tissue-derived stromal cells for the repair of corneal and intra-orbital defects and uses thereof
TWI290055B (en) * 2002-03-14 2007-11-21 Tissuetech Inc Amniotic membrane covering for a tissue surface and devices facilitating fastening of membranes
US20030187515A1 (en) * 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
ATE521697T1 (en) * 2002-03-29 2011-09-15 Singapore Eye Res Inst METHOD FOR GROWING HUMAN CONNECTIVE TISSUE EQUIVALENTS FOR RESEARCH, CLINICAL EYE SURFACE TRANSPLANTATION AND TISSUE CONSTRUCTION
JPWO2004018658A1 (en) * 2002-08-23 2005-12-08 宣男 櫻川 Human bone stem cells
AU2003272536A1 (en) * 2002-09-18 2004-04-08 Emiliano Ghinelli Use of a human amniotic membrane composition for prophylaxis and treatment of diseases and conditions of the eye and skin
JP2006501848A (en) * 2002-10-04 2006-01-19 ティシュテク，インク． Culture and transplantation of retinal pigment epithelial cells in amniotic membrane
KR101042448B1 (en) 2002-11-26 2011-06-16 안트로제네시스 코포레이션 Cytotherapeutics, cytotherapeutic units and methods for treatments using them
US7727550B2 (en) * 2003-02-21 2010-06-01 The Uab Research Foundation Biologically active native biomatrix composition
US20050026279A1 (en) * 2003-04-28 2005-02-03 Tseng Scheffer C.G. Surgical grafts and methods of preparation
US20070010008A1 (en) * 2005-06-29 2007-01-11 Tissuetech, Inc. Ex vivo expansion of primary animal cells
WO2005021014A1 (en) * 2003-09-03 2005-03-10 Jiuchang Miao Preparation of biological amnion preservable at room temperature
ES2396689T3 (en) 2003-12-11 2013-02-25 Isto Technologies Inc. Particle Cartilage System
US20050186672A1 (en) * 2004-01-27 2005-08-25 Reliance Life Sciences Pvt. Ltd. Tissue system with undifferentiated stem cells derived from corneal limbus
US20060216821A1 (en) * 2004-02-26 2006-09-28 Reliance Life Sciences Pvt. Ltd. Pluripotent embryonic-like stem cells derived from corneal limbus, methods of isolation and uses thereof
US8187875B2 (en) * 2004-02-26 2012-05-29 Reliance Life Sciences Pvt. Ltd. Dopaminergic neurons derived from corneal limbus, methods of isolation and uses thereof
WO2005097190A2 (en) * 2004-03-26 2005-10-20 Celgene Corporation Systems and methods for providing a stem cell bank
US20050287223A1 (en) * 2004-06-23 2005-12-29 Peyman Gholam A Use of amniotic membrane as biocompatible devices
DK1789534T3 (en) 2004-08-16 2014-11-17 Cellres Corp Pte Ltd ISOLATION OF stem / progenitor cells FOSTER HINDE FROM an umbilical cord
CN103361303B (en) 2005-03-31 2015-09-30 斯丹姆涅恩有限公司 Prepare a kind of method of the highly purified cell mass from amnion
US20070038298A1 (en) * 2005-06-30 2007-02-15 Sulner Joseph W Repair of tympanic membrane using placenta derived collagen biofabric
GB0514567D0 (en) * 2005-07-15 2005-08-24 Univ Nottingham Surgical membrane
US8932641B2 (en) * 2005-08-26 2015-01-13 Amnos Co., Ltd. Dried amnion and method for drying treatment of amnion
US8480757B2 (en) 2005-08-26 2013-07-09 Zimmer, Inc. Implants and methods for repair, replacement and treatment of disease
ES2713062T3 (en) * 2005-09-27 2019-05-17 Tissuetech Inc Amniotic membrane preparations and purified compositions and methods of use
US8187639B2 (en) * 2005-09-27 2012-05-29 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
NZ597304A (en) 2005-10-13 2013-06-28 Anthrogenesis Corp Immunomodulation using placental stem cells
FR2892311B1 (en) * 2005-10-24 2012-09-28 Ets Francais Du Sang DRESSING FOR HEALING OF WOUNDS, ULCERS OR BURNS OF EPITHELIUMS, ENDOTHELIUMS OR MUCOUS MEMBRANES.
JP5550235B2 (en) 2005-12-29 2014-07-16 アントフロゲネシス コーポレーション Placental stem cell population
AU2006332679A1 (en) 2005-12-29 2007-07-12 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
WO2007099556A2 (en) * 2006-02-24 2007-09-07 Reliance Life Sciences Pvt Ltd. Conjunctival tissue system
SI2772535T1 (en) 2006-05-31 2022-08-31 Children's Medical Center Corporation ABC5 positive mesenchymal stem cells as immunomodulators
CA2654716A1 (en) * 2006-06-09 2007-12-21 Anthrogenesis Corporation Placental niche and use thereof to culture stem cells
US8105634B2 (en) * 2006-08-15 2012-01-31 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
US20080131522A1 (en) * 2006-10-03 2008-06-05 Qing Liu Use of placental biomaterial for ocular surgery
US8071135B2 (en) 2006-10-04 2011-12-06 Anthrogenesis Corporation Placental tissue compositions
NZ576372A (en) 2006-10-06 2012-02-24 Anthrogenesis Corp Native (telopeptide) placental collagen compositions
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
EP2118267B1 (en) 2007-01-17 2017-03-15 Noveome Biotherapeutics, Inc. Novel methods for modulating inflammatory and/or immune responses
CN103356711A (en) 2007-02-12 2013-10-23 人类起源公司 Immunomodulation using placental stem cells
JP2010518812A (en) 2007-02-12 2010-06-03 アンスロジェネシス コーポレーション Hepatocytes and chondrocytes derived from adherent placental stem cells, and enriched cell populations of CD34 +, CD45− placental stem cells
US20080233552A1 (en) * 2007-03-22 2008-09-25 David Hui-Kang Ma Method of cross-linking amnion to be an improved biomedical material
WO2008128075A1 (en) 2007-04-12 2008-10-23 Isto Technologies, Inc. Compositions and methods for tissue repair
WO2008127656A1 (en) 2007-04-12 2008-10-23 The Brigham And Women's Hospital, Inc. Targeting abcb5 for cancer therapy
US8273526B2 (en) 2007-06-18 2012-09-25 Children's Hospital & Research Center At Oakland Method of isolating stem and progenitor cells from placenta
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
WO2009033160A1 (en) 2007-09-07 2009-03-12 Surgical Biologics Placental tissue grafts and improved methods of preparing and using the same
AU2008307633C1 (en) 2007-09-28 2015-04-30 Celularity Inc. Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
WO2009044408A1 (en) * 2007-10-03 2009-04-09 International Centre For Cardio Thoracic And Vascular Diseases (A Unit Of Frontier Lifeline Pvt. Ltd) A treated amniotic membrane and method of treating amniotic membrane
US20090163990A1 (en) * 2007-12-19 2009-06-25 Chunlin Yang Decellularized omentum matrix and uses thereof
US8735054B1 (en) 2008-01-04 2014-05-27 Lifecell Corporation Acellular tissue matrix preservation solution
KR100947553B1 (en) * 2008-02-14 2010-03-12 주식회사 바이오랜드 Biological implantation material and method for preparing same
US9358320B2 (en) 2008-04-25 2016-06-07 Allosource Multi-layer tissue patches
KR20110013419A (en) * 2008-04-25 2011-02-09 알로소스 Anti-adhesion barrier wound dressing comprising processed amniotic tissue and method of use
US9480549B2 (en) 2008-04-25 2016-11-01 Allosource Multi-layer tissue patches
US8709096B2 (en) * 2008-04-29 2014-04-29 Proxy Biomedical Limited Tissue repair implant
JP6169316B2 (en) 2008-08-20 2017-07-26 アンスロジェネシス コーポレーション Improved cell composition and method for producing the same
KR20180108887A (en) 2008-08-20 2018-10-04 안트로제네시스 코포레이션 Treatment of stroke using isolated placental cells
MX2011001992A (en) 2008-08-22 2011-03-29 Anthrogenesis Corp Methods and compositions for treatment of bone defects with placental cell populations.
US8858698B2 (en) * 2008-09-05 2014-10-14 Mentor Worldwide Llc Acellular matrix glue
US7927414B2 (en) * 2008-09-05 2011-04-19 Ethicon, Inc. Method of manufacturing acellular matrix glue
EP2356446A4 (en) 2008-11-14 2014-03-19 Brigham & Womens Hospital Therapeutic and diagnostic methods relating to cancer stem cells
US11542328B2 (en) 2008-11-14 2023-01-03 The Brigham And Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells
RU2562154C2 (en) 2008-11-19 2015-09-10 Антродженезис Корпорейшн Amniotic adhesive cells
US8771677B2 (en) * 2008-12-29 2014-07-08 Vladimir B Serikov Colony-forming unit cell of human chorion and method to obtain and use thereof
US9150318B1 (en) 2009-01-02 2015-10-06 Lifecell Corporation Method for sterilizing an acellular tissue matrix
JP5693475B2 (en) * 2009-03-04 2015-04-01 ペイタント・ソリューションズ・インコーポレイテッドＰｅｙｔａｎｔ Ｓｏｌｕｔｉｏｎｓ， Ｉｎｃ． Stent modified with a material comprising amnion tissue and corresponding method
CN101508971B (en) * 2009-03-23 2011-04-06 中国海洋大学 Tissue engineering reconstruction method for human corneal endothelium
ES2559029T3 (en) 2009-04-24 2016-02-10 Tissue Tech, Inc. Compositions containing the HC.HA complex and methods of use thereof
EP2449095A1 (en) 2009-07-02 2012-05-09 Anthrogenesis Corporation Method of producing erythrocytes without feeder cells
US8348929B2 (en) 2009-08-05 2013-01-08 Rocin Laboratories, Inc. Endoscopically-guided tissue aspiration system for safely removing fat tissue from a patient
US20110213336A1 (en) 2009-08-05 2011-09-01 Cucin Robert L Method of and apparatus for sampling, processing and collecting tissue and reinjecting the same into human patients
US8465471B2 (en) 2009-08-05 2013-06-18 Rocin Laboratories, Inc. Endoscopically-guided electro-cauterizing power-assisted fat aspiration system for aspirating visceral fat tissue within the abdomen of a patient
CA2771908C (en) * 2009-08-25 2019-05-21 Tissuetech, Inc. Umbilical cord amniotic membrane products
ES2646750T3 (en) 2010-01-26 2017-12-15 Anthrogenesis Corporation Treatment of bone-related cancers using placental stem cells
EP2536823B1 (en) * 2010-02-18 2017-12-20 Osiris Therapeutics, Inc. Methods of manufacture of immunocompatible chorionic membrane products
KR20190076060A (en) 2010-04-07 2019-07-01 안트로제네시스 코포레이션 Angiogenesis using placental stem cells
EP2555783A1 (en) 2010-04-08 2013-02-13 Anthrogenesis Corporation Treatment of sarcoidosis using placental stem cells
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8840665B2 (en) 2010-06-11 2014-09-23 Liventa Bioscience, Inc. Method of tendon repair with amnion and chorion constructs
WO2012003377A2 (en) * 2010-06-30 2012-01-05 Tissuetech, Inc. Methods of preparing chorion tissue and products derived therefrom
US20120010708A1 (en) * 2010-07-08 2012-01-12 AFcell Medical Amnion and chorion replacement cover and uses thereof in surgical repair of muscles
WO2012009422A1 (en) 2010-07-13 2012-01-19 Anthrogenesis Corporation Methods of generating natural killer cells
US8969315B2 (en) 2010-12-31 2015-03-03 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
US9526770B2 (en) 2011-04-28 2016-12-27 Tissuetech, Inc. Methods of modulating bone remodeling
ES2707579T3 (en) 2011-06-01 2019-04-04 Celularity Inc Pain treatment using placental cytoblast
US9682044B2 (en) 2011-06-10 2017-06-20 Tissuetech, Inc. Methods of processing fetal support tissues, fetal support tissue powder products, and uses thereof
CN102908678A (en) * 2011-08-05 2013-02-06 高传友 Lacrimal passage rod placed in lacrimal passage for treating eye diseases
WO2013055476A1 (en) 2011-09-09 2013-04-18 Anthrogenesis Corporation Treatment of amyotrophic lateral sclerosis using placental stem cells
US9585983B1 (en) * 2011-10-12 2017-03-07 BioDlogics, LLC Wound covering and method of preparation
US8932805B1 (en) 2011-10-31 2015-01-13 BioDlogics, LLC Birth tissue material and method of preparation
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
US8961617B2 (en) 2012-03-08 2015-02-24 Liventa Bioscience, Inc. Amnion and chorion constructs and uses thereof in abdominal surgery
US9308082B2 (en) 2012-08-07 2016-04-12 RegenEye, L.L.C. Ocular collar stent for treating narrowing of the irideocorneal angle
US10265161B2 (en) 2012-08-07 2019-04-23 Regeneye L. L. C. Ocular collar stent for treating narrowing of the irideocorneal angle
US9974645B2 (en) 2012-08-07 2018-05-22 RegenEye, L.L.C. Method of reducing the occurrence of macular and neuroretinal degenerations by alleviating age related retinal stresses as a contributing factor in a mammalian eye
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
US10905800B1 (en) 2013-01-29 2021-02-02 BioDlogics, LLC Ocular covering and method of use
WO2014120946A1 (en) * 2013-01-30 2014-08-07 NuTech Medical, Inc. Placental membrane preparation and methods of making and using same
AU2014215458A1 (en) 2013-02-05 2015-08-13 Anthrogenesis Corporation Natural killer cells from placenta
CA2901931C (en) 2013-02-19 2023-03-07 Children's Medical Center Corporation Abcb5(+) stem cells for treating ocular disease
US9498327B1 (en) 2013-03-05 2016-11-22 Biodlogics Llc Repair of tympanic membrane using human birth tissue material
US9789138B1 (en) 2013-03-06 2017-10-17 BioDlogics, LLC Neural repair construct and method of use
US11077229B1 (en) 2013-03-08 2021-08-03 BioDlogics, LLC Implant coating composition and method of use
US9770472B1 (en) * 2013-03-08 2017-09-26 Brahm Holdings, Llc Organ jacket and methods of use
US9446077B2 (en) 2013-03-13 2016-09-20 Allosource Fascia fibrous compositions and methods for their use and manufacture
US9855301B1 (en) 2013-03-13 2018-01-02 Biodlogics Llc Human birth tissue laminate and methods of use
US9511119B2 (en) 2013-03-15 2016-12-06 NuTech Spine, Inc. Preparations containing hepatocyte growth factor and hyaluronic acid and methods of making and using same
KR102312720B1 (en) 2013-03-15 2021-10-13 알로소스 Cell repopulated collagen matrix for soft tissue repair and regeneration
US9795638B1 (en) 2013-03-16 2017-10-24 BioDlogics, LLC Cardiothoracic construct and methods of use
US10039792B1 (en) 2013-03-16 2018-08-07 Brahm Holdings, Llc Methods for the treatment of inflammation and pain using human birth tissue material composition
US9795639B1 (en) 2013-03-16 2017-10-24 BioDlogics, LLC Methods for the treatment of erectile dysfunction by human birth tissue material compostion
US10555897B1 (en) 2013-03-16 2020-02-11 Brahm Holdings Llc Cosmetic composition and methods of treatment
US9993506B1 (en) 2013-03-16 2018-06-12 BioDlogics, Inc. Methods for the treatment of degenerative disc diseases by human birth tissue material composition
WO2014182994A1 (en) 2013-05-10 2014-11-13 Children's Medical Center Corporation Wound healing and tissue engineering
AU2014360195B2 (en) 2013-12-06 2018-02-08 Allosource Method of drying sheets of tissue
WO2015171144A1 (en) * 2014-05-07 2015-11-12 Osiris Therapeutics, Inc. Immunocompatible amniotic membrane products
TW201603818A (en) 2014-06-03 2016-02-01 組織科技股份有限公司 Compositions and methods
KR20170020527A (en) 2014-06-27 2017-02-22 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 Cultured mammalian limbal stem cells, methods for generating the same, and uses thereof
CL2014002088A1 (en) * 2014-08-06 2015-03-13 Hernan Vasquez Zuloaga Dario Amniotic membrane packaging process that maintains its structure for use as a graft, which comprises adhering said membrane to a support, dimensioning the membrane together with the support by means of an inert cutting device, gluing the membrane together with the support inside a container and sterilize it; amniotic membrane and its use
US10201573B1 (en) 2014-10-27 2019-02-12 Brahm Holdings, Llc Human birth tissue material composition and methods for the treatment of damage associated with a cerebral vascular accident
US10265438B1 (en) 2014-11-03 2019-04-23 BioDlogics, LLC Methods and compositions for the repair and replacement of connective tissue
US10765705B2 (en) 2014-11-24 2020-09-08 Prime Merger Sub, Llc Visco-supplement compositions, and methods of use thereof
WO2016138025A2 (en) 2015-02-23 2016-09-01 Tissuetech, Inc. Apparatuses and methods for treating ophthalmic diseases and disorders
US10603174B2 (en) 2015-03-24 2020-03-31 Osiris Therapeutics, Inc. Compositions comprising meniscal tissues and uses thereof
CN104826166B (en) * 2015-05-06 2017-06-06 广州优适清生物科技有限公司 A kind of biomembrane for glaucoma treatment and preparation method thereof
CN104825493B (en) * 2015-05-06 2020-02-21 广州瑞泰生物科技有限公司 Biological amniotic membrane for ocular surface treatment and preparation method thereof
CN107847526A (en) 2015-05-20 2018-03-27 组织技术公司 For preventing the propagation of epithelial cell and the composition and method of the conversion of epithelium mesenchyma
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
CA3007417A1 (en) * 2015-12-11 2017-06-15 Lifecell Corporation Methods and systems for stiffening of tissue for improved processing
CA3009178A1 (en) 2015-12-23 2017-06-29 Lifenet Health Decellularized placental membrane and methods of preparing and use thereof
TW201733600A (en) 2016-01-29 2017-10-01 帝聖工業公司 Fetal support tissue products and methods of use
FR3047899A1 (en) 2016-02-18 2017-08-25 Tbf - Genie Tissulaire Et Par Abreviation Tbf PROCESS FOR PREPARING AN ALLOGRAFT MATERIAL, PRODUCT OBTAINED, AND USES THEREOF
CN105561393A (en) * 2016-02-25 2016-05-11 岳邦超 Amniotic membrane sclera lens support
US10687934B2 (en) * 2016-07-05 2020-06-23 Carlos A. Alvarado Serous membrane for ocular surface disorders
US10271942B2 (en) 2016-08-24 2019-04-30 Arthrex, Inc. Tissue use for repair of injury
US10772986B2 (en) 2017-01-26 2020-09-15 Allosource Fascia fibrous compositions and methods for their use and manufacture
CN107296041B (en) * 2017-07-02 2020-12-25 江西瑞济生物工程技术股份有限公司 Fresh amnion preservation solution, fresh amnion preservation method and application
CN107952113A (en) * 2017-12-04 2018-04-24 遵义医学院 A kind of preparation method and application of people's amnion nerve channel
US11285177B2 (en) 2018-01-03 2022-03-29 Globus Medical, Inc. Allografts containing viable cells and methods thereof
US20220008518A1 (en) * 2018-11-08 2022-01-13 The Schepens Eye Research Institute, Inc. Therapeutic approaches for tissue reconstruction and wound healing treatment
US11511017B2 (en) 2019-03-12 2022-11-29 Arthrex, Inc. Ligament reconstruction
CN110404119B (en) * 2019-08-29 2023-04-07 上海越增生物科技有限公司 Preparation method of amnion tissue engineering immunogen-removing skin scaffold
CN110975012B (en) * 2019-12-05 2021-11-16 博雅干细胞科技有限公司 Method for preparing de-epithelialized amniotic membrane
US11161204B1 (en) 2020-04-10 2021-11-02 Amnio Technology Llc Allograft optimization system
WO2022098755A1 (en) * 2020-11-05 2022-05-12 Mimedx Group, Inc. Meshed placental membrane tissue grafts
CN115105636B (en) * 2022-07-16 2024-03-19 沈阳汇智细胞产业技术创新研究院有限公司 Preparation method of acellular human amniotic membrane

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL47062A (en) * 1975-04-10 1979-07-25 Yeda Res & Dev Process for diminishing antigenicity of tissues to be usedas transplants by treatment with glutaraldehyde
JPS5251009A (en) 1975-10-17 1977-04-23 Morinaga Milk Ind Co Ltd Method of producing drug for treating marrow leukemia
US4361552A (en) * 1980-09-26 1982-11-30 Board Of Regents, The University Of Texas System Wound dressing
US4599226A (en) * 1983-03-31 1986-07-08 Genetic Laboratories, Inc. Wound dressing comprising silver sulfadiazine incorporated in animal tissue and method of preparation
US4599084A (en) 1983-05-24 1986-07-08 American Hospital Supply Corp. Method of using biological tissue to promote even bone growth
US4829000A (en) 1985-08-30 1989-05-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Reconstituted basement membrane complex with biological activity
EP0265906B1 (en) 1986-10-31 1995-04-19 Nippon Zeon Co., Ltd. Wound dressing
US5135915A (en) 1988-10-14 1992-08-04 Genentech, Inc. Method for the treatment of grafts prior to transplantation using TGF-.beta.
WO1991001720A1 (en) 1989-08-07 1991-02-21 Herman Wade Schlameus Composition and method of promoting hard tissue healing
JPH07504398A (en) 1991-03-26 1995-05-18 オレゴン州 Products and methods for improving epidermal keratinocyte adhesion to the dermis
US5437287A (en) 1992-08-17 1995-08-01 Carbomedics, Inc. Sterilization of tissue implants using iodine
IL112580A0 (en) * 1994-02-24 1995-05-26 Res Dev Foundation Amniotic membrane graft of wrap to prevent adhesions or bleeding of internal organs
DE19511126A1 (en) * 1995-03-19 1996-09-26 Dizg Deutsches Inst Fuer Zell Substrate cell layers, e.g. for transplantation
DE29520965U1 (en) * 1995-03-19 1996-10-02 Dizg Deutsches Inst Fuer Zell Cell layers and transport system for cell layers
EP0735135A3 (en) * 1995-03-31 1997-12-29 DIZG Deutsches Institüt für Zell- und Gewebeersatz gGmbH Cell sheets and transport system for cell sheets

Also Published As

Publication number Publication date
US6326019B1 (en) 2001-12-04
JP2002515899A (en) 2002-05-28
EP0918529A4 (en) 2003-02-05
EP0918529A1 (en) 1999-06-02
EP0918529B1 (en) 2008-05-07
BR9805921A (en) 2000-01-25
WO1998037903A1 (en) 1998-09-03
US6152142A (en) 2000-11-28
DE69839437D1 (en) 2008-06-19
TW398982B (en) 2000-07-21
ES2307314T3 (en) 2008-11-16
CA2252758C (en) 2008-05-13

Similar Documents

Publication Publication Date Title
CA2252758A1 (en) Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries
Quinby Jr et al. Clinical trials of amniotic membranes in burn wound care
CA2084648A1 (en) Cryopreservation of cultured epithelial sheets
US5040677A (en) Container for storage and distribution of a skin wound dressing
CA2335686A1 (en) Particulate acellular tissue matrix
EP1637037A3 (en) Method for processing and preserving collagen-based tissues for transplantation
EP0790767A2 (en) Wound repair dressings and methods for their preservation
GB9400163D0 (en) Membrane
WO1993010722A3 (en) Fetal membrane tubes for nerve and vessel grafts
WO2000001231A8 (en) Improved methods for storing neural cells
CA2147123A1 (en) Use of a cell membrane permeant calcium buffer for reducing injury of mammalian cells in vivo
WO2002024244A3 (en) Method of preparing and processing transplant tissue
CA2044143A1 (en) Method of preventing or limiting reperfusion damage
Lin et al. Amnion overlay meshed skin autograft
JPH06503735A (en) Wound dressing and its manufacturing method
Ingemansson et al. Long-term preservation of vascular endothelium and smooth muscle
BAXTER et al. Experimental and Clinical Studies of Reduced Temperatures in Injury and Repair in Man: III. Direct Effect of Cooling and Freezing on Various Elements of the Human Skin
DE69422806T2 (en) MANUFACTURE OF MATRICES
Dioguardi et al. Skin substitutes in burn treatment-our experience
CA2089336A1 (en) Method for processing and preserving collagen-based tissues for transplantation
Burke et al. Primary excision and prompt grafting as routine therapy for the treatment of thermal burns in children
Richards et al. Experimental observations on vein graft myringoplasty
Kakibuchi et al. The use of cultivated epidermal cell sheets in skin grafting
Nakashima et al. Experience with lateral upper arm flaps
AU1315492A (en) Composition for tissues to sustain viability and biological functions in surgery and storage

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20180226