CA2267897A1 - Infrared spectroscopy and imaging of libraries - Google Patents

Infrared spectroscopy and imaging of libraries

Info

Publication number
CA2267897A1
CA2267897A1 CA002267897A CA2267897A CA2267897A1 CA 2267897 A1 CA2267897 A1 CA 2267897A1 CA 002267897 A CA002267897 A CA 002267897A CA 2267897 A CA2267897 A CA 2267897A CA 2267897 A1 CA2267897 A1 CA 2267897A1
Authority
CA
Canada
Prior art keywords
array
compounds
another aspect
imaging techniques
screened
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002267897A
Other languages
French (fr)
Other versions
CA2267897C (en
Inventor
Eric W. Mcfarland
William Archibald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Symyx Technologies Inc
Original Assignee
Symyx Technologies
Eric W. Mcfarland
William Archibald
Symyx Technologies, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27574147&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2267897(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/898,715 external-priority patent/US6030917A/en
Application filed by Symyx Technologies, Eric W. Mcfarland, William Archibald, Symyx Technologies, Inc. filed Critical Symyx Technologies
Publication of CA2267897A1 publication Critical patent/CA2267897A1/en
Application granted granted Critical
Publication of CA2267897C publication Critical patent/CA2267897C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • G01N29/22—Details, e.g. general constructional or apparatus details
    • G01N29/24—Probes
    • G01N29/2418—Probes using optoacoustic interaction with the material, e.g. laser radiation, photoacoustics
    • G01N29/2425—Probes using optoacoustic interaction with the material, e.g. laser radiation, photoacoustics optoacoustic fluid cells therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
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    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/006—Palladium compounds
    • C07F15/0066—Palladium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
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    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
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Abstract

Methods and apparatus for screening diverse arrays of materials using infrared imaging techniques are provided. Typically, each of the individual materials on the array will be screened or interrogated for the same material characteristic.
Once screened, the individual materials may be ranked or otherwise compared relative to each other with respect to the material characteristic under investigation. According to one aspect, infrared imaging techniques are used to identify the active sites within an array of compounds by monitoring the temperature change resulting from a reaction. This same technique can also be used to quantify the stability of each new material within an array of compounds. According to another aspect, identification and characterization of condensed phase products is achieved, wherein library elements are activated by a heat source serially, or in parallel. According to another aspect, a Fourier transform infrared spectrometer is used to rapidly characterize a large number of chemical reactions contained within a combinatorial library.
CA002267897A 1996-10-09 1997-10-07 Infrared spectroscopy and imaging of libraries Expired - Fee Related CA2267897C (en)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US2810596P 1996-10-09 1996-10-09
US2810696P 1996-10-09 1996-10-09
US60/028,106 1996-10-09
US60/028,105 1996-10-09
US2925596P 1996-10-25 1996-10-25
US60/029,255 1996-10-25
US3536697P 1997-01-10 1997-01-10
US3520297P 1997-01-10 1997-01-10
US60/035,366 1997-01-10
US60/035,202 1997-01-10
US4898797P 1997-06-09 1997-06-09
US60/048,987 1997-06-09
US5094997P 1997-06-13 1997-06-13
US60/050,949 1997-06-13
US08/898,715 US6030917A (en) 1996-07-23 1997-07-22 Combinatorial synthesis and analysis of organometallic compounds and catalysts
US08/898,715 1997-07-22
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