CA2271595A1 - Modular home dialysis system - Google Patents

Modular home dialysis system

Info

Publication number
CA2271595A1
CA2271595A1 CA002271595A CA2271595A CA2271595A1 CA 2271595 A1 CA2271595 A1 CA 2271595A1 CA 002271595 A CA002271595 A CA 002271595A CA 2271595 A CA2271595 A CA 2271595A CA 2271595 A1 CA2271595 A1 CA 2271595A1
Authority
CA
Canada
Prior art keywords
machine
water
control
integral water
temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002271595A
Other languages
French (fr)
Other versions
CA2271595C (en
Inventor
Rodney S. Kenley
Dawn Matthews
Douglas L. Wilkerson
Dennis M. Treu
Frederick H. Peter, Jr.
Tom L. Brose
Eric Bell
Thomas M. Feldsten
Kenneth E. Pawlak
Donald C. Walker
H. Gordon Minns
Wayne F. Adolf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HHD LLC
Original Assignee
Aksys, Ltd.
Rodney S. Kenley
Dawn Matthews
Douglas L. Wilkerson
Dennis M. Treu
Frederick H. Peter, Jr.
Tom L. Brose
Eric Bell
Thomas M. Feldsten
Kenneth E. Pawlak
Donald C. Walker
H. Gordon Minns
Wayne F. Adolf
Durus Life Sciences Master Fund, Ltd.
Hhd Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23533428&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2271595(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aksys, Ltd., Rodney S. Kenley, Dawn Matthews, Douglas L. Wilkerson, Dennis M. Treu, Frederick H. Peter, Jr., Tom L. Brose, Eric Bell, Thomas M. Feldsten, Kenneth E. Pawlak, Donald C. Walker, H. Gordon Minns, Wayne F. Adolf, Durus Life Sciences Master Fund, Ltd., Hhd Llc filed Critical Aksys, Ltd.
Publication of CA2271595A1 publication Critical patent/CA2271595A1/en
Application granted granted Critical
Publication of CA2271595C publication Critical patent/CA2271595C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D65/00Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B01D65/10Testing of membranes or membrane apparatus; Detecting or repairing leaks
    • B01D65/102Detection of leaks in membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/04Heat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18Liquid substances or solutions comprising solids or dissolved gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
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    • A61M1/1601Control or regulation
    • A61M1/1603Regulation parameters
    • A61M1/1605Physical characteristics of the dialysate fluid
    • A61M1/1607Physical characteristics of the dialysate fluid before use, i.e. upstream of dialyser
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    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601Control or regulation
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    • A61M1/1621Constructional aspects thereof
    • A61M1/1649Constructional aspects thereof with pulsatile dialysis fluid flow
    • AHUMAN NECESSITIES
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    • A61M1/1621Constructional aspects thereof
    • A61M1/165Constructional aspects thereof with a dialyser bypass on the dialysis fluid line
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    • A61M1/1654Dialysates therefor
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    • A61M1/166Heating
    • AHUMAN NECESSITIES
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    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654Dialysates therefor
    • A61M1/1656Apparatus for preparing dialysates
    • A61M1/166Heating
    • A61M1/1662Heating with heat exchange between fresh and used dialysate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M1/1654Dialysates therefor
    • A61M1/1656Apparatus for preparing dialysates
    • A61M1/1666Apparatus for preparing dialysates by dissolving solids
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    • A61M1/1654Dialysates therefor
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    • A61M1/1654Dialysates therefor
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    • AHUMAN NECESSITIES
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/11Laminar flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/65Impedance, e.g. conductivity, capacity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • A61M39/16Tube connectors; Tube couplings having provision for disinfection or sterilisation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2311/00Details relating to membrane separation process operations and control
    • B01D2311/04Specific process operations in the feed stream; Feed pretreatment
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2321/00Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
    • B01D2321/04Backflushing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2321/00Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
    • B01D2321/16Use of chemical agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2321/00Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
    • B01D2321/32By heating or pyrolysis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S210/00Liquid purification or separation
    • Y10S210/929Hemoultrafiltrate volume measurement or control processes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S215/00Bottles and jars
    • Y10S215/03Medical
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/7722Line condition change responsive valves
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/7722Line condition change responsive valves
    • Y10T137/7781With separate connected fluid reactor surface
    • Y10T137/7793With opening bias [e.g., pressure regulator]
    • Y10T137/7794With relief valve
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/7722Line condition change responsive valves
    • Y10T137/7781With separate connected fluid reactor surface
    • Y10T137/7793With opening bias [e.g., pressure regulator]
    • Y10T137/7796Senses inlet pressure
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/7722Line condition change responsive valves
    • Y10T137/7781With separate connected fluid reactor surface
    • Y10T137/7793With opening bias [e.g., pressure regulator]
    • Y10T137/7797Bias variable during operation
    • Y10T137/7799Liquid transfer

Abstract

A machine for conducting dialysis of body fluids of a patient. The machine includes integral water preparation and treatment, dialysate preparation, and extracorporeal circuit modules, under computer control from a patient interface and control module. A
water pretreatment module with a temperature-controlled mixing valve, an integral water filtration and conditioning unit and a pressure relief with integral water sample removal port supplies water to the machine. The dialysate preparation module includes a substantially non-compliant tank with attached batch chemical bottles and automatic chemical addition and dispersion subsystems. The machine incorporates novel automatic process control techniques to verify the status and integrity of the critical system components, ultrafiltration control, and temperature, pressure and conductivity conditions prior to dialysis.
CA002271595A 1995-02-13 1996-02-01 Modular home dialysis system Expired - Fee Related CA2271595C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/388,275 1995-02-13
US08/388,275 US5591344A (en) 1995-02-13 1995-02-13 Hot water disinfection of dialysis machines, including the extracorporeal circuit thereof
CA002168629A CA2168629C (en) 1995-02-13 1996-02-01 Modular home dialysis system

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002168629A Division CA2168629C (en) 1995-02-13 1996-02-01 Modular home dialysis system

Publications (2)

Publication Number Publication Date
CA2271595A1 true CA2271595A1 (en) 1996-08-14
CA2271595C CA2271595C (en) 2003-05-06

Family

ID=23533428

Family Applications (5)

Application Number Title Priority Date Filing Date
CA002168629A Expired - Fee Related CA2168629C (en) 1995-02-13 1996-02-01 Modular home dialysis system
CA002271598A Expired - Fee Related CA2271598C (en) 1995-02-13 1996-02-01 Modular home dialysis system
CA002271586A Expired - Fee Related CA2271586C (en) 1995-02-13 1996-02-01 Modular home dialysis system
CA002271595A Expired - Fee Related CA2271595C (en) 1995-02-13 1996-02-01 Modular home dialysis system
CA002271583A Expired - Fee Related CA2271583C (en) 1995-02-13 1996-02-01 Modular home dialysis system

Family Applications Before (3)

Application Number Title Priority Date Filing Date
CA002168629A Expired - Fee Related CA2168629C (en) 1995-02-13 1996-02-01 Modular home dialysis system
CA002271598A Expired - Fee Related CA2271598C (en) 1995-02-13 1996-02-01 Modular home dialysis system
CA002271586A Expired - Fee Related CA2271586C (en) 1995-02-13 1996-02-01 Modular home dialysis system

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002271583A Expired - Fee Related CA2271583C (en) 1995-02-13 1996-02-01 Modular home dialysis system

Country Status (7)

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US (20) US5591344A (en)
JP (10) JP2002503115A (en)
AU (2) AU4977996A (en)
CA (5) CA2168629C (en)
DE (7) DE19605260B4 (en)
GB (10) GB2299026B (en)
WO (1) WO1996025214A1 (en)

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