CA2275763A1 - Combatting infection in delivery systems - Google Patents

Combatting infection in delivery systems Download PDF

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Publication number
CA2275763A1
CA2275763A1 CA002275763A CA2275763A CA2275763A1 CA 2275763 A1 CA2275763 A1 CA 2275763A1 CA 002275763 A CA002275763 A CA 002275763A CA 2275763 A CA2275763 A CA 2275763A CA 2275763 A1 CA2275763 A1 CA 2275763A1
Authority
CA
Canada
Prior art keywords
delivery systems
combatting
infection
combatting infection
taurolidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002275763A
Other languages
French (fr)
Other versions
CA2275763C (en
Inventor
Joachim Hermann Lehner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Geistlich Pharma AG
Original Assignee
Ed Geistlich Soehne Ag Fuer Chemische Industrie
Joachim Hermann Lehner
Geistlich Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10804970&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2275763(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ed Geistlich Soehne Ag Fuer Chemische Industrie, Joachim Hermann Lehner, Geistlich Pharma Ag filed Critical Ed Geistlich Soehne Ag Fuer Chemische Industrie
Publication of CA2275763A1 publication Critical patent/CA2275763A1/en
Application granted granted Critical
Publication of CA2275763C publication Critical patent/CA2275763C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Abstract

The use of taurolidine or taurultam in a method of combatting infection or sepsis in delivery systems is disclosed. In the method, taurolidine or taurultam solutions are used as a temporary seal or flush to prevent or reduce sepsis in delivery systems, such as port systems and/or catheters by which liquids are delivered into a patient.
CA002275763A 1996-12-23 1997-12-23 Combatting infection in delivery systems Expired - Lifetime CA2275763C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9626795.0 1996-12-23
GBGB9626795.0A GB9626795D0 (en) 1996-12-23 1996-12-23 Combating infection in delivery systems
PCT/GB1997/003524 WO1998028027A1 (en) 1996-12-23 1997-12-23 Combatting infection in delivery systems

Publications (2)

Publication Number Publication Date
CA2275763A1 true CA2275763A1 (en) 1998-07-02
CA2275763C CA2275763C (en) 2006-11-21

Family

ID=10804970

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002275763A Expired - Lifetime CA2275763C (en) 1996-12-23 1997-12-23 Combatting infection in delivery systems

Country Status (9)

Country Link
US (1) US6258797B1 (en)
EP (1) EP0946221B1 (en)
JP (1) JP4373500B2 (en)
AT (1) ATE337786T1 (en)
CA (1) CA2275763C (en)
DE (2) DE946221T1 (en)
ES (1) ES2177483T3 (en)
GB (1) GB9626795D0 (en)
WO (1) WO1998028027A1 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9626795D0 (en) 1996-12-23 1997-02-12 Geistlich Soehne Ag Combating infection in delivery systems
US20050124608A1 (en) * 2001-04-03 2005-06-09 Redmond H. P. Treatment of cancers
US8304390B2 (en) * 1997-07-31 2012-11-06 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method of treatment for preventing or reducing tumor growth in the liver of patient
US7132413B1 (en) 1997-07-31 2006-11-07 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Anticoagulant/sterilizing compositions and methods
US20070275955A1 (en) * 1997-07-31 2007-11-29 Ed. Geistlich Soehne Ag Method of treating tumors
US6166007A (en) † 1998-07-02 2000-12-26 Sodemann; Klaus Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof
CA2302720C (en) * 1999-03-29 2009-07-14 Ed Geistlich Sohne Ag Fur Chemische Industrie Anticoagulant/sterilizing compositions and methods
US7345039B2 (en) * 1999-06-04 2008-03-18 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer
US8030301B2 (en) 1999-06-04 2011-10-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of cancers with methylol-containing compounds and at least one electrolyte
US7892530B2 (en) 1999-06-04 2011-02-22 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of tumor metastases and cancer
US6641571B2 (en) * 2000-01-05 2003-11-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery
JP5143982B2 (en) * 2001-05-08 2013-02-13 エヌディー パートナーズ，リミティド ライアビリティー カンパニー Biocide lock
US20040092890A1 (en) * 2001-05-10 2004-05-13 Ash Stephen R. Catheter lock solution including a photo-oxidant
US20050215978A1 (en) * 2001-05-25 2005-09-29 Ash Stephen R Method of enhancing catheter patency using a citrate salt catheter lock solution
JP4458240B2 (en) * 2001-11-26 2010-04-28 ジェネンテック インコーポレイテッド Catheter composition and its use
US6803363B2 (en) * 2002-05-31 2004-10-12 Nd Partners, Llc Peritoneal dialysis solution with taurolidine
ES2282529T3 (en) * 2003-02-03 2007-10-16 Hans-Dietrich Dr.Techn. Polaschegg COMPOSITION FOR THE PREVENTION OF AN INFECTION DUE TO A PERMANENT DEVICE.
JP5346148B2 (en) * 2003-03-28 2013-11-20 エー・デー・ガイストリヒ・ゾーネ・アクチェンゲゼルシャフト・フュール・ヒェーミシェ・インダストリー Antineoplastic compositions and methods of treatment
DE10331557B3 (en) * 2003-07-11 2005-02-17 Herdeis, Claus, Prof. Dr. Use of taurolidine and taurultam in preparations for the treatment, cleaning, storage and conditioning of contact lenses
US7696182B2 (en) 2004-11-02 2010-04-13 Nd Partners, Llc Antimicrobial locking solutions comprising taurinamide derivatives and biologically acceptable salts and acids, with the addition of small concentrations of heparin
US7749529B2 (en) 2005-02-08 2010-07-06 Ash Access Technology, Inc. Catheter lock solution comprising citrate and a paraben
ATE414518T1 (en) 2006-07-25 2008-12-15 Claus Herdeis PREPARATION OF ANTIMICROBIAL FORMULATIONS USING 7-OXA-2-THIA 1,5- DIAZABICYCLOÄ3.3.1UNONAN-2,2-DIONE
CA2668347C (en) 2006-11-07 2017-06-20 Genentech, Inc. Tissue plasminogen activator variant uses
US8389583B2 (en) 2008-05-23 2013-03-05 Zurex Pharma, Inc. Antimicrobial compositions and methods of use
US9248093B2 (en) 2009-06-11 2016-02-02 Becton, Dickinson And Company Catheter locking solution having antimicrobial and anticoagulation properties
JP5379192B2 (en) * 2011-07-01 2013-12-25 エヌディー パートナーズ，リミティド ライアビリティー カンパニー Biocide lock
US11738120B1 (en) 2022-04-14 2023-08-29 Cormedix Inc. Synthesis of taurolidine, purity profiles and polymorphs

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1124285A (en) 1964-10-06 1968-08-21 Geistlich Soehne Ag Novel perhydro-1,2,4-thiadiazine dioxides-(1,1), their preparation and compositionscontaining them
CA1190855A (en) 1980-09-03 1985-07-23 Rolf W. Pfirrmann Treatment of osteitis
DE3506288A1 (en) 1984-09-06 1986-03-13 Johannes 7900 Ulm Reinmüller DEVICE FOR INSERTING IN Wounds and Wound Caves
DE3533612A1 (en) 1985-09-20 1987-04-02 Johannes Reinmueller INNOVATIVE USE OF TAUROLIN
US5210083A (en) * 1986-07-17 1993-05-11 Ed. Geistlich Sohne A.G. Fur Chemische Industrie Pharmaceutical compositions
US5167960A (en) 1988-08-03 1992-12-01 New England Deaconess Hospital Corporation Hirudin-coated biocompatible substance
US5263930A (en) 1990-03-01 1993-11-23 William D. Ensminger Implantable access devices
US5352204A (en) * 1990-03-01 1994-10-04 Ensminger William D Implantable access devices
DK0591152T3 (en) * 1990-11-02 1996-07-22 Marion Giebel Infection prevention catheter device
DE19606897C2 (en) 1996-02-13 2002-08-29 Geistlich Soehne Ag Means for preventing the spread of tumor cells and the development of trocar metastases in open and laparoscopic surgery of malignant tumors
US6146363A (en) 1996-10-24 2000-11-14 Giebel; Marion Anti-infection catheter
GB9626795D0 (en) 1996-12-23 1997-02-12 Geistlich Soehne Ag Combating infection in delivery systems
GB9716219D0 (en) 1997-07-31 1997-10-08 Geistlich Soehne Ag Prevention of metastases
US6166007A (en) 1998-07-02 2000-12-26 Sodemann; Klaus Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof
US6174537B1 (en) 1998-09-25 2001-01-16 Becton, Dickinson And Company Catheter flush solution and method for its use

Also Published As

Publication number Publication date
GB9626795D0 (en) 1997-02-12
EP0946221A1 (en) 1999-10-06
EP0946221B1 (en) 2006-08-30
ES2177483T1 (en) 2002-12-16
WO1998028027A1 (en) 1998-07-02
ES2177483T3 (en) 2007-03-16
DE946221T1 (en) 2002-11-14
DE69736605D1 (en) 2006-10-12
JP2001507019A (en) 2001-05-29
ATE337786T1 (en) 2006-09-15
JP4373500B2 (en) 2009-11-25
US6258797B1 (en) 2001-07-10
CA2275763C (en) 2006-11-21
DE69736605T2 (en) 2007-09-20

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Effective date: 20171227