CA2276736A1 - Microplate assembly and closures - Google Patents

Microplate assembly and closures Download PDF

Info

Publication number
CA2276736A1
CA2276736A1 CA002276736A CA2276736A CA2276736A1 CA 2276736 A1 CA2276736 A1 CA 2276736A1 CA 002276736 A CA002276736 A CA 002276736A CA 2276736 A CA2276736 A CA 2276736A CA 2276736 A1 CA2276736 A1 CA 2276736A1
Authority
CA
Canada
Prior art keywords
caps
vials
closure
wells
microplate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002276736A
Other languages
French (fr)
Other versions
CA2276736C (en
Inventor
Kimberly R. Gamble
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wheaton Industries Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2276736A1 publication Critical patent/CA2276736A1/en
Application granted granted Critical
Publication of CA2276736C publication Critical patent/CA2276736C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates

Abstract

A microplate assembly with closure comprises a microplate base 101 having a geometric array of wells 103. Vials 113 of borosilicate glass inserted into the wells comprise flanges on the top portion of the vials. Closure 117 comprises an array of caps 119 having a complementary geometric pattern to the wells of the microplate base. The caps each comprise a septum and are connected by a thin membrane 121. Each cap comprises a sidewall 403 having a vial engagement ring which snaps over the flange 115 of the vials. Septum openings 135 in the caps extend through the top of the caps and provide a means to fill and evacuate the vials with a penetration device passing through the septa of the caps of the closure.
CA002276736A 1998-06-30 1999-06-29 Microplate assembly and closures Expired - Lifetime CA2276736C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/108,339 1998-06-30
US09/108,339 US6106783A (en) 1998-06-30 1998-06-30 Microplate assembly and closure

Publications (2)

Publication Number Publication Date
CA2276736A1 true CA2276736A1 (en) 1999-12-30
CA2276736C CA2276736C (en) 2003-10-07

Family

ID=22321640

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002276736A Expired - Lifetime CA2276736C (en) 1998-06-30 1999-06-29 Microplate assembly and closures

Country Status (5)

Country Link
US (2) US6106783A (en)
EP (1) EP0976453B1 (en)
AT (1) ATE267046T1 (en)
CA (1) CA2276736C (en)
DE (2) DE976453T1 (en)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6193088B1 (en) * 1996-02-26 2001-02-27 Monty E. Vincent Flask vent and method of making same
DE19746455C1 (en) * 1997-10-21 1999-05-27 Jenoptik Jena Gmbh Automatic pipetting and handling device for microtitration plates with permeable bottoms
ITPD980166A1 (en) * 1998-07-02 2000-01-02 Kaltek Srl CONTAINER OF LIQUIDS PARTICULARLY FOR ANALYSIS OF BIOLOGICAL LIQUIDS.
FR2780903B1 (en) * 1998-07-13 2000-09-29 Central Labo Europ PLATE, IN PARTICULAR FOR MICROTITRATION, HAVING A PLURALITY OF BUCKETS FOR RECEIVING SAMPLES OF A BIOLOGICAL LIQUID
EP1156879A1 (en) 1999-02-05 2001-11-28 Robbins Scientific Corporation Multi-well array with adjustable plenum
US6627157B1 (en) * 1999-03-04 2003-09-30 Ut-Battelle, Llc Dual manifold system and method for fluid transfer
DE19917375C2 (en) * 1999-04-16 2001-09-27 Hamilton Bonaduz Ag Bonaduz Pipetting unit
US6399394B1 (en) * 1999-06-30 2002-06-04 Agilent Technologies, Inc. Testing multiple fluid samples with multiple biopolymer arrays
DE19934090A1 (en) * 1999-07-19 2001-02-08 Cybio Instr Gmbh Flushing tub system
US6241949B1 (en) * 1999-08-17 2001-06-05 Spectrumedix Corporation Spill-resistant microtitre trays and method of making
NL1012996C2 (en) * 1999-09-08 2001-03-12 Micronic B V Sealing mat for sealing test tubes.
US20020055708A1 (en) * 1999-09-24 2002-05-09 Peterson Kenneth R. Coupling syringe system and methods for obtaining a mixed composition
US8226598B2 (en) 1999-09-24 2012-07-24 Tolmar Therapeutics, Inc. Coupling syringe system and methods for obtaining a mixed composition
US6908594B1 (en) * 1999-10-22 2005-06-21 Aclara Biosciences, Inc. Efficient microfluidic sealing
US6455005B1 (en) * 2000-02-02 2002-09-24 Soltec, Inc. Flexible septa closure plug mats for well plate mounted arrays of sample vials
DE10013240A1 (en) * 2000-03-09 2001-10-11 Brand Gmbh & Co Kg Arrangement for contamination-free processing of, in particular, molecular biological reaction sequences, closure carrier and individual closure for such an arrangement, and storage and dispensing arrangement for individual closures
DE10012575A1 (en) 2000-03-15 2001-09-27 Schott Glas Transport unit for medicinal containers comprises a plastic carrier plate with openings, with the cross section of the openings and the thickness of the carrier plate chosen so that the containers are centrally clamped
US6626870B1 (en) 2000-03-27 2003-09-30 Artix Laboratories, Inc. Stoppering method to maintain sterility
US6566144B1 (en) 2000-03-27 2003-05-20 Atrix Laboratories Cover plate for use in lyophilization
WO2001080997A1 (en) * 2000-04-19 2001-11-01 Corning Incorporated Multi-well plate and method of manufacture
US7018589B1 (en) * 2000-07-19 2006-03-28 Symyx Technologies, Inc. High pressure parallel reactor
AU2001100242B4 (en) * 2000-08-08 2001-08-30 Robert Alexander Micro titre tray assembly and viral diagnostic kit including same
US6562301B1 (en) 2000-10-27 2003-05-13 Varian, Inc. Vessel centering system and method
US6673319B2 (en) * 2000-10-27 2004-01-06 Varian, Inc. Vessel centering system and method
EP1234614A1 (en) * 2001-02-27 2002-08-28 Pentapharm Gmbh Metering vessel subdivided by ribs for receiving reagents, its fabrication and use
US6890488B2 (en) * 2001-06-22 2005-05-10 Matrix Technologies, Inc. Apparatus for sealing test tubes and the like
US7115232B2 (en) * 2001-07-13 2006-10-03 Hudson Gordon S Fluorescence validation microplate and method of use
US6682703B2 (en) * 2001-09-05 2004-01-27 Irm, Llc Parallel reaction devices
US7854896B2 (en) * 2001-09-25 2010-12-21 Becton, Dickinson And Company Closed system storage plates
GB0128350D0 (en) * 2001-11-27 2002-01-16 Lab901 Ltd Non-rigid apparatus for microfluidic applications
US20030143124A1 (en) * 2002-01-31 2003-07-31 Roberts Roger Q. Unidirectional flow control sealing matt
US7537936B2 (en) 2002-05-31 2009-05-26 Agilent Technologies, Inc. Method of testing multiple fluid samples with multiple biopolymer arrays
US20030235519A1 (en) * 2002-06-24 2003-12-25 Corning Incorporated Protein crystallography hanging drop lid that individually covers each of the wells in a microplate
US20040048392A1 (en) * 2002-09-09 2004-03-11 The Gov't Of The U.S.A As Represented By The Secretary Of The Dept.Of Health And Human Services Container for drying biological samples, method of making such container, and method of using same
JP4299837B2 (en) * 2002-12-20 2009-07-22 ザ シャーロット‐メクレンバーグ ホスピタル オーソリティ Disposable handheld device for collection of exhaled breath condensate
US7828741B2 (en) * 2002-12-20 2010-11-09 The Charlotte-Mecklenburg Hospital Authority Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia
WO2004065009A1 (en) 2003-01-17 2004-08-05 Greiner Bio-One Gmbh Sample vessel for analyses
US9005549B2 (en) 2003-01-17 2015-04-14 Greiner Bio-One Gmbh High throughput polymer-based microarray slide
US8490790B2 (en) 2003-02-24 2013-07-23 Becton Dickinson France S.A.S. Plate for holding a group of syringe body objects
FI115060B (en) * 2003-04-22 2005-02-28 Chip Man Technologies Oy Analysis and breeding equipment
US6981624B2 (en) * 2003-07-22 2006-01-03 Skirts Plus Corporation Ammunition carrier system
US20050186578A1 (en) * 2004-02-20 2005-08-25 Sven Bulow Chamber array arrangement
US20060024209A1 (en) * 2004-07-30 2006-02-02 Agnew Brian J Apparatus, methods, and kits for assaying a plurality of fluid samples for a common analyte
US7854343B2 (en) * 2005-03-10 2010-12-21 Labcyte Inc. Fluid containers with reservoirs in their closures and methods of use
US20060286003A1 (en) * 2005-06-16 2006-12-21 Desilets Kenneth G Multi-well filter plate with shifted wells and U-bottom receiver plate
US20070059221A1 (en) * 2005-09-09 2007-03-15 Sorensen David K Test tube storage system
US20090215998A1 (en) * 2005-11-21 2009-08-27 Barofoid, Inc. Devices and methods for high-pressure refolding of proteins
CN101415455B (en) * 2006-02-28 2011-11-23 株式会社大协精工 Piston suit piece for injector
US20070272587A1 (en) * 2006-05-22 2007-11-29 Nguyen Viet X Vial package
US7851204B2 (en) * 2006-06-09 2010-12-14 Pall Microreactor Technologies, Inc. Closure for milliliter scale bioreactor
DE102006044324A1 (en) * 2006-09-18 2008-03-27 Labor L + S Aktiengesellschaft Method for the photometric measurement of a liquid sample contained in sample container, comprises irradiating liquid sample during the measurement with a photometric measuring beam and detecting its absorption
AU2007308865A1 (en) * 2006-10-27 2008-05-02 Sierra Molecular Corporation Penetratable septum cap
GB2445739A (en) 2007-01-16 2008-07-23 Lab901 Ltd Polymeric laminates containing heat seals
EP1970711A1 (en) * 2007-03-16 2008-09-17 Radiometer Medical ApS Reagent cup device
US20080233015A1 (en) * 2007-03-23 2008-09-25 Bioinnovations Oy Device and method for use in analysis
US7807109B2 (en) 2007-05-14 2010-10-05 Freeslate, Inc. Parallel batch reactor with pressure monitoring
US20080286170A1 (en) * 2007-05-14 2008-11-20 Symyx Technologies, Inc. Parallel batch reactor
US7655191B2 (en) * 2007-05-14 2010-02-02 Symyx Solutions, Inc. Methods for chemical reactions in a parallel batch reactor
US20080293157A1 (en) * 2007-05-24 2008-11-27 Gerald Frederickson Apparatus and method of performing high-throughput cell-culture studies on biomaterials
ES2688901T3 (en) * 2007-12-26 2018-11-07 Daikyo Seiko, Ltd. Rubber molds
WO2010049108A1 (en) * 2008-10-28 2010-05-06 Grünenthal GmbH Reactor array for producing and analyzing products
US8591840B2 (en) * 2009-01-23 2013-11-26 Eppendorf Ag Carrier for pipette tips
WO2011005801A1 (en) * 2009-07-08 2011-01-13 Speware Corporation Luer seal for solid phase extraction columns
CN103921966B (en) * 2009-08-10 2016-07-06 西部制药服务公司 For loading the method without flange container
US20120175368A1 (en) * 2010-07-06 2012-07-12 Speware Corporation Luer seal for solid phase extraction columns
GB201018624D0 (en) * 2010-11-04 2010-12-22 Epistem Ltd Reaction vessel
US10723497B2 (en) 2014-11-03 2020-07-28 Vanrx Pharmasystems Inc. Apparatus and method for monitoring and controlling the filling of a container with a pharmaceutical fluid in an aseptic environment
US8741236B2 (en) * 2012-08-20 2014-06-03 Biochemical Diagnostics, Inc. Microwell covers for microplates
US9844781B2 (en) 2012-08-20 2017-12-19 Biochemical Diagnostics, Inc. Microwell covers for microplates
US8808644B2 (en) 2012-08-20 2014-08-19 Biochemical Diagnostics, Inc. Methods for dispensing fluids into microplates utilizing microwell covers
US9573128B1 (en) 2012-09-06 2017-02-21 SciKon Innovation, Inc. Fluidics device allowing fluid flow between a plurality of wells
WO2014074887A1 (en) * 2012-11-09 2014-05-15 Peter Honkanen Methods of and systems for improved detection sensitivity of assays
USD732187S1 (en) 2013-02-07 2015-06-16 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For An On Behalf Of Arizona State University Aliquot tray
TW201900137A (en) * 2013-08-16 2019-01-01 加拿大商凡爾克斯醫藥系統公司 Method, device and system for filling and lyophilizing drug containers
USD767783S1 (en) * 2013-08-23 2016-09-27 SciKon Innovation, Inc. Assay tray assembly
CN106062169B (en) * 2013-09-13 2019-08-13 杭州金源生物技术有限公司 Seal cap array, gasket, sample cell band and porous plate component
USD766455S1 (en) * 2014-04-11 2016-09-13 Marvin Smollar Allergy testing tray
US10035145B2 (en) 2014-12-02 2018-07-31 SciKon Innovation, Inc. Piston assembly and related systems for use with a fluidics device
USD804050S1 (en) * 2015-02-03 2017-11-28 ABgene Limited Combined polymerase chain reaction multi-well plate and plate of caps
WO2016154361A1 (en) 2015-03-23 2016-09-29 SciKon Innovation, Inc. A method and related systems for use with a fluidics device
CN108602066B (en) * 2015-12-01 2021-08-17 亿明达股份有限公司 Liquid storage and delivery mechanism and method
EP3411647A4 (en) * 2016-02-05 2019-09-25 Tolmar Therapeutics, Inc. Vented cover plate for an array of syringes
US9931635B1 (en) * 2016-09-15 2018-04-03 Pall Corporation Cover for microplate of multiwell assembly and method of processing fluid sample
USD838004S1 (en) 2017-01-25 2019-01-08 Arizona Board Of Regents On Behalf Of Arizona State University Aliquot tray
USD841832S1 (en) 2017-02-17 2019-02-26 Arizona Board Of Regents On Behalf Of Arizona State University Aliquot tray
WO2019126827A1 (en) 2017-12-22 2019-06-27 West Pharmaceuticals Services, Inc. Packaging system for aseptic filling of small volume vials
USD908916S1 (en) 2018-06-19 2021-01-26 Tolmar Therapeutics, Inc. Syringe restrictor plate
GB201812637D0 (en) * 2018-08-03 2018-09-19 Randox Laboratories Ltd PCR cartridge
CN109850832A (en) * 2018-12-14 2019-06-07 中玉金标记（北京）生物技术股份有限公司 Pressing machine
US11642677B2 (en) * 2019-12-05 2023-05-09 QIS, Inc. Split microplate and vials
FR3114086B1 (en) * 2020-09-11 2023-11-10 A Raymond Et Cie SYSTEM AND METHOD FOR PACKAGING MEDICAL CONTAINERS
JP7015076B1 (en) * 2020-10-01 2022-02-02 バイオソリューションズ株式会社 Microplate seal device
WO2023069022A2 (en) * 2021-10-21 2023-04-27 Star Array Pte. Ltd. Device and method for processing biological samples
JP1712510S (en) * 2021-11-30 2022-04-13 Cell observation container

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3649464A (en) * 1969-12-05 1972-03-14 Microbiological Ass Inc Assay and culture tray
DE2834186C2 (en) * 1978-08-04 1980-04-24 Bodenseewerk Perkin-Elmer & Co Gmbh, 7770 Ueberlingen Closure for sample bottles
US4496657A (en) * 1982-10-14 1985-01-29 Scripps Clinic And Research Foundation Microplate washer
US4599314A (en) * 1983-06-14 1986-07-08 Hsc Research Development Corporation Multiple vessel specimen tray with lid for releasably adhering vessel covers
US4557393A (en) * 1984-04-17 1985-12-10 Continental White Cap, Inc. Snap-on cap with tethering strap
AT380392B (en) * 1985-01-24 1986-05-12 C A Greiner & S Hne Ges M B H BLOOD SAMPLING!
EP0213653B1 (en) * 1985-08-19 1989-11-15 Akzo N.V. Device for the carrying out of an immunochemical determination
US4960219A (en) * 1989-09-08 1990-10-02 Abbott Laboratories Snap cap
US5271903A (en) * 1990-10-02 1993-12-21 Dionex Corporation Supercritical fluid extraction restrictor and collection system
KR940701227A (en) * 1991-07-22 1994-05-28 차알스 엠. 브로크 Reusable Sealing Assembly for Diagnostic Test Reagent Packs
TW223593B (en) * 1992-04-09 1994-05-11 Hoffmann La Roche
US5514343A (en) * 1994-06-22 1996-05-07 Nunc, As Microtitration system
US5721136A (en) * 1994-11-09 1998-02-24 Mj Research, Inc. Sealing device for thermal cycling vessels
US5683659A (en) * 1995-02-22 1997-11-04 Hovatter; Kenneth R. Integral assembly of microcentrifuge strip tubes and strip caps
US5707589A (en) * 1996-04-12 1998-01-13 Merlin Instrument Company Funnel-shaped sample-vial septum with membrane covered diffusion-barrier section
GB2322121A (en) * 1997-02-13 1998-08-19 Porvair Plc Multi-well plate closure

Also Published As

Publication number Publication date
EP0976453A2 (en) 2000-02-02
ATE267046T1 (en) 2004-06-15
USRE38312E1 (en) 2003-11-11
EP0976453B1 (en) 2004-05-19
DE69917386D1 (en) 2004-06-24
DE976453T1 (en) 2001-02-08
DE69917386T2 (en) 2005-06-30
EP0976453A3 (en) 2000-07-19
CA2276736C (en) 2003-10-07
US6106783A (en) 2000-08-22

Similar Documents

Publication Publication Date Title
CA2276736A1 (en) Microplate assembly and closures
US5718348A (en) Overcap assembly for gear finish vial
CA2054949A1 (en) Closure devices for enteral fluid containers
USD298592S (en) Jar
ATE211901T1 (en) CONNECTION SYSTEM FOR TWO VIALS FOR FREEZE-DRIED PRODUCTS
CA2298700A1 (en) Tamper evident bottle cap
AU5787886A (en) Container sealing cap
IE40445B1 (en) Closure
CA2455289A1 (en) A closure cap
GB1483790A (en) Safety vial and cap therefor
ES265665Y (en) A PLUG FOR A BOTTLE OR "VIAL".
CA2022445A1 (en) Snap cap
FR2655620B1 (en) SCREW CAPPING CAP, WITH A BAND OF INVIOLABILITY.
CA2348562A1 (en) Cap with angled upper skirt
DE69001033D1 (en) AIRTIGHT ROAD CAP LOCK.
ITMI930394V0 (en) PLASTIC CAPSULA IN PARTICULAR FOR INFUSION AND INJECTABLE BOTTLES
USD280594S (en) Bottle cap opener
US4742927A (en) Tamper proof seal for a container closure
ATE222874T1 (en) CLOSING DEVICE FOR BEVERAGE CANS, PARTICULARLY FOR CARBONATED BEVERAGES
DE3869460D1 (en) GLASS BOTTLE CAP.
USD448297S1 (en) Screw-top closure with crown cap
DE29923461U1 (en) Microplate assembly and closure
DE3764956D1 (en) PLUG FOR CLOSING TUBES AND BOTTLES, IN PARTICULAR FOR PHARMACEUTICAL PRODUCTS.
CN210765345U (en) Prevent that liquid pollutes culture dish that film formed that volatilizees fast
IT1220581B (en) CAP FOR CONTAINERS FORMED BY TWO ELEMENTS ENCLOSED BETWEEN THEM WITH HIGH GUARANTEE AGAINST TAMPERING

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20190702