CA2297817A1 - Osmotic delivery system flow modulator apparatus and method - Google Patents

Osmotic delivery system flow modulator apparatus and method Download PDF

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Publication number
CA2297817A1
CA2297817A1 CA002297817A CA2297817A CA2297817A1 CA 2297817 A1 CA2297817 A1 CA 2297817A1 CA 002297817 A CA002297817 A CA 002297817A CA 2297817 A CA2297817 A CA 2297817A CA 2297817 A1 CA2297817 A1 CA 2297817A1
Authority
CA
Canada
Prior art keywords
delivery system
osmotic delivery
flow modulator
system flow
modulator assembly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002297817A
Other languages
French (fr)
Other versions
CA2297817C (en
Inventor
Lewis L. Peterson
Fred H. Maruyama
Houdin Dehnad
Craig R. Davis
Lawton Hom
John Peery
Kevin Ly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intarcia Therapeutics Inc
Original Assignee
Alza Corporation
Lewis L. Peterson
Fred H. Maruyama
Houdin Dehnad
Craig R. Davis
Lawton Hom
John Peery
Kevin Ly
Intarcia Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corporation, Lewis L. Peterson, Fred H. Maruyama, Houdin Dehnad, Craig R. Davis, Lawton Hom, John Peery, Kevin Ly, Intarcia Therapeutics, Inc. filed Critical Alza Corporation
Publication of CA2297817A1 publication Critical patent/CA2297817A1/en
Application granted granted Critical
Publication of CA2297817C publication Critical patent/CA2297817C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/141—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor with capillaries for restricting fluid flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14526—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons the piston being actuated by fluid pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A61M5/16813—Flow controllers by controlling the degree of opening of the flow line
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/494—Fluidic or fluid actuated device making

Abstract

An osmotic delivery system flow modulator assembly, an osmotic delivery system with a flow modulator assembly, and a method of assembling an osmotic delivery system. The osmotic delivery system flow modulator assembly includes a body having a hole located through the body and communicating two opposing ends of the body. The use of the osmotic delivery system flow modulator assembly lessens the chance that air or gas pockets will form in the enclosure of the osmotic delivery system during assembly of the system. Because less air is within the osmotic delivery system, performance of the system is enhanced. Use of the flow modulator assembly also lessens the chance that beneficial agent will be wasted during assembly of the osmotic delivery system.
CA002297817A 1997-07-25 1998-07-24 Osmotic delivery system flow modulator apparatus and method Expired - Fee Related CA2297817C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5369097P 1997-07-25 1997-07-25
US60/053,690 1997-07-25
PCT/US1998/014813 WO1999004768A2 (en) 1997-07-25 1998-07-24 Osmotic delivery system flow modulator apparatus

Publications (2)

Publication Number Publication Date
CA2297817A1 true CA2297817A1 (en) 1999-02-04
CA2297817C CA2297817C (en) 2007-05-22

Family

ID=21985903

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002297817A Expired - Fee Related CA2297817C (en) 1997-07-25 1998-07-24 Osmotic delivery system flow modulator apparatus and method

Country Status (19)

Country Link
US (4) US6524305B1 (en)
EP (1) EP0998273B1 (en)
JP (1) JP2001510792A (en)
KR (1) KR100523201B1 (en)
CN (1) CN1198601C (en)
AR (1) AR013255A1 (en)
AT (1) ATE276747T1 (en)
AU (1) AU8493898A (en)
CA (1) CA2297817C (en)
CO (1) CO4890860A1 (en)
DE (1) DE69826479T2 (en)
DK (1) DK0998273T3 (en)
ES (1) ES2226159T3 (en)
HK (1) HK1027752A1 (en)
MY (1) MY125870A (en)
PT (1) PT998273E (en)
TW (1) TW384226B (en)
WO (1) WO1999004768A2 (en)
ZA (1) ZA986629B (en)

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US20080071253A1 (en) 2008-03-20
US20050131389A1 (en) 2005-06-16
WO1999004768A3 (en) 1999-04-08
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CN1265030A (en) 2000-08-30
AR013255A1 (en) 2000-12-13
DE69826479T2 (en) 2005-09-29
EP0998273A2 (en) 2000-05-10
US20030114837A1 (en) 2003-06-19
ZA986629B (en) 1999-02-04
DE69826479D1 (en) 2004-10-28
ATE276747T1 (en) 2004-10-15
ES2226159T3 (en) 2005-03-16
KR20010022223A (en) 2001-03-15
CN1198601C (en) 2005-04-27
CO4890860A1 (en) 2000-02-28
KR100523201B1 (en) 2005-10-21
DK0998273T3 (en) 2005-01-31
EP0998273B1 (en) 2004-09-22
WO1999004768A2 (en) 1999-02-04
AU8493898A (en) 1999-02-16
US6840931B2 (en) 2005-01-11
TW384226B (en) 2000-03-11
US6524305B1 (en) 2003-02-25
JP2001510792A (en) 2001-08-07
MY125870A (en) 2006-08-30
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CA2297817C (en) 2007-05-22
US7407500B2 (en) 2008-08-05

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