CA2321836A1 - Automated molecular pathology apparatus having independent slide heaters - Google Patents

Automated molecular pathology apparatus having independent slide heaters Download PDF

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Publication number
CA2321836A1
CA2321836A1 CA002321836A CA2321836A CA2321836A1 CA 2321836 A1 CA2321836 A1 CA 2321836A1 CA 002321836 A CA002321836 A CA 002321836A CA 2321836 A CA2321836 A CA 2321836A CA 2321836 A1 CA2321836 A1 CA 2321836A1
Authority
CA
Canada
Prior art keywords
molecular pathology
independent slide
automated molecular
pathology apparatus
slide heaters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002321836A
Other languages
French (fr)
Other versions
CA2321836C (en
Inventor
William Richards
Charles D. Lemme
Kimberly Christensen
Ethel Macrea
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ventana Medical Systems Inc
Original Assignee
Ventana Medical Systems, Inc.
William Richards
Charles D. Lemme
Kimberly Christensen
Ethel Macrea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventana Medical Systems, Inc., William Richards, Charles D. Lemme, Kimberly Christensen, Ethel Macrea filed Critical Ventana Medical Systems, Inc.
Publication of CA2321836A1 publication Critical patent/CA2321836A1/en
Application granted granted Critical
Publication of CA2321836C publication Critical patent/CA2321836C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002—Reagent dispensers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1079—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices with means for piercing stoppers or septums

Abstract

Apparatus and methods for automatically staining or treating multiple tissue samples mounted on microscope slides are provided. Individualized slide temperature control is accomplished by the heating system according to the present invention that has thermal platforms radially mounted to the carousel for heating the slides and sensing the temperature of each. The heating system also permits automated de-waxing if necessary.
CA002321836A 1998-02-27 1999-02-26 Automated molecular pathology apparatus having independent slide heaters Expired - Lifetime CA2321836C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7619898P 1998-02-27 1998-02-27
US60/076,198 1998-02-27
PCT/US1999/004181 WO1999044030A1 (en) 1998-02-27 1999-02-26 Automated molecular pathology apparatus having independent slide heaters

Publications (2)

Publication Number Publication Date
CA2321836A1 true CA2321836A1 (en) 1999-09-02
CA2321836C CA2321836C (en) 2004-09-28

Family

ID=22130540

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002321836A Expired - Lifetime CA2321836C (en) 1998-02-27 1999-02-26 Automated molecular pathology apparatus having independent slide heaters
CA002320750A Expired - Lifetime CA2320750C (en) 1998-02-27 1999-02-26 System and method of aspirating and dispensing reagent

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002320750A Expired - Lifetime CA2320750C (en) 1998-02-27 1999-02-26 System and method of aspirating and dispensing reagent

Country Status (10)

Country Link
US (1) US6296809B1 (en)
EP (3) EP2284543A3 (en)
JP (5) JP3847559B2 (en)
CN (1) CN100403008C (en)
AT (1) ATE489613T1 (en)
AU (3) AU763354B2 (en)
CA (2) CA2321836C (en)
DE (1) DE69942975D1 (en)
ES (1) ES2354598T3 (en)
WO (2) WO1999044030A1 (en)

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