CA2336207A1 - Ecdysone receptors and methods for their use - Google Patents

Ecdysone receptors and methods for their use Download PDF

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Publication number
CA2336207A1
CA2336207A1 CA002336207A CA2336207A CA2336207A1 CA 2336207 A1 CA2336207 A1 CA 2336207A1 CA 002336207 A CA002336207 A CA 002336207A CA 2336207 A CA2336207 A CA 2336207A CA 2336207 A1 CA2336207 A1 CA 2336207A1
Authority
CA
Canada
Prior art keywords
methods
ecdysone
novel
polypeptides
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002336207A
Other languages
French (fr)
Other versions
CA2336207C (en
Inventor
Marc C. Albertsen
Catherine D. Brooke
Carl W. Garnaat
Bradley Allen Roth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pioneer Hi Bred International Inc
Original Assignee
Pioneer Hi-Bred International, Inc.
Marc C. Albertsen
Catherine D. Brooke
Carl W. Garnaat
Bradley Allen Roth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pioneer Hi-Bred International, Inc., Marc C. Albertsen, Catherine D. Brooke, Carl W. Garnaat, Bradley Allen Roth filed Critical Pioneer Hi-Bred International, Inc.
Publication of CA2336207A1 publication Critical patent/CA2336207A1/en
Application granted granted Critical
Publication of CA2336207C publication Critical patent/CA2336207C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43577—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

The field of the invention is inducible gene expression systems wherein expression is controlled by a novel ecdysone receptor or its derivatives. The field particularly relates to the isolation and characterization of nucleic acid and polypeptides for a novel ecdysone receptor. The nucleic acid and polypeptides are useful in novel gene expression systems inducible with ecdysone or derivative receptor agonists.
CA002336207A 1998-09-10 1999-09-10 Ecdysone receptors and methods for their use Expired - Fee Related CA2336207C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9979398P 1998-09-10 1998-09-10
US60/099,793 1998-09-10
PCT/US1999/020715 WO2000015791A1 (en) 1998-09-10 1999-09-10 Ecdysone receptors and methods for their use

Publications (2)

Publication Number Publication Date
CA2336207A1 true CA2336207A1 (en) 2000-03-23
CA2336207C CA2336207C (en) 2004-03-23

Family

ID=22276654

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002336207A Expired - Fee Related CA2336207C (en) 1998-09-10 1999-09-10 Ecdysone receptors and methods for their use

Country Status (9)

Country Link
US (4) US6504082B1 (en)
EP (1) EP1112360A1 (en)
JP (1) JP2002525053A (en)
AR (1) AR021484A1 (en)
AU (1) AU5915999A (en)
CA (1) CA2336207C (en)
HU (1) HUP0103993A3 (en)
MX (1) MXPA01002529A (en)
WO (1) WO2000015791A1 (en)

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US6489140B1 (en) * 1998-11-06 2002-12-03 Nancy Wisnewski Flea ecdysone and ultraspiracle nucleic acid molecules, proteins and uses thereof
US20040033600A1 (en) * 2001-03-21 2004-02-19 Palli Subba Reddy Ecdysone receptor-based inducible gene expression system
DE10036469A1 (en) * 2000-07-25 2002-02-28 Bayer Ag Ultraspiracle (USP) protein from Heliothis virescens
US7517975B2 (en) 2000-09-26 2009-04-14 Pioneer Hi-Bred International, Inc. Nucleotide sequences mediating male fertility and method of using same
US8105825B2 (en) 2000-10-03 2012-01-31 Intrexon Corporation Multiple inducible gene regulation system
AU2002251724B2 (en) * 2000-10-24 2007-06-21 Syngenta Participations Ag Control of gene expression in plants
EP3470520A2 (en) * 2001-02-20 2019-04-17 Intrexon Corporation Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
ES2385598T3 (en) 2001-02-20 2012-07-27 Intrexon Corporation Novel inducible gene expression system based on the ecdysone receptor / X retinoid invertebrate receptor
WO2002066615A2 (en) 2001-02-20 2002-08-29 Rheogene, Inc. Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
ES2424812T3 (en) 2001-02-20 2013-10-08 Intrexon Corporation Chimeric X retinoid receptors and their use in an inducible gene expression system based on novel ecdysone receptors
US7081350B2 (en) 2001-09-07 2006-07-25 Regents Of The University Of Minnesota Methods for identifying ecdysteroid synthesis inhibitors using the drosophila P450 enzyme shade
CA2459827C (en) * 2001-09-26 2013-09-03 Subba Reddy Palli Leafhopper ecdysone receptor nucleic acids, polypeptides, and uses thereof
WO2004048583A2 (en) * 2002-11-22 2004-06-10 Institut Clayton De La Recherche Compositions and systems for the regulation of genes
US7422863B2 (en) 2003-02-07 2008-09-09 Kumiai Chemical Industry Co., Ltd. Molting hormone receptor and method for screening ligand to the receptor
US20070169227A1 (en) 2003-12-16 2007-07-19 Pioneer Hi-Bred International Inc. Dominant Gene Suppression Transgenes and Methods of Using Same
PL1696721T3 (en) 2003-12-16 2010-07-30 Pioneer Hi Bred Int Dominant gene suppression transgenes and methods of using same
US20050164210A1 (en) * 2004-01-23 2005-07-28 Vivek Mittal Regulated polymerase III expression systems and related methods
US7935510B2 (en) * 2004-04-30 2011-05-03 Intrexon Corporation Mutant receptors and their use in a nuclear receptor-based inducible gene expression system
US8115059B1 (en) 2005-07-22 2012-02-14 University Of Kentucky Research Foundation Gene expression modulation system for use in plants and method for modulating gene expression in plants
EP2041284B1 (en) 2006-07-05 2021-05-26 Arkansas State University Research and Development Institute Production of stilbenes and stilbene derivatives in plant hairy root cultures
EP2164863A4 (en) 2007-06-15 2010-07-28 Univ Arkansas Methods of delivery of molecules to cells using a ricin subunit and compositions relating to same
EP2631243A3 (en) 2007-08-03 2013-11-20 Pioneer Hi-Bred International Inc. Msca1 nucleotide sequences impacting plant male fertility and method of using same
CA2849390A1 (en) * 2010-09-21 2012-03-29 Donald Danforth Plant Science Center Metabolic control of seed germination
WO2012074868A2 (en) 2010-12-03 2012-06-07 Ms Technologies, Llc Optimized expression of glyphosate resistance encoding nucleic acid molecules in plant cells
US8648230B2 (en) 2011-03-18 2014-02-11 Ms Technologies, Llc Regulatory regions preferentially expressing in non-pollen plant tissue
AR090418A1 (en) 2012-02-01 2014-11-12 Dow Agrosciences Llc TRANSIT PEPTIDE
WO2013134651A1 (en) 2012-03-09 2013-09-12 Board Of Trustees Of Michigan State University Method of enhancing plant drought tolerance by expression of ndr1
CN104703998B (en) 2012-03-13 2020-08-21 先锋国际良种公司 Genetic reduction of male fertility in plants
WO2013138309A1 (en) 2012-03-13 2013-09-19 Pioneer Hi-Bred International, Inc. Genetic reduction of male fertility in plants
US9598707B2 (en) 2012-11-26 2017-03-21 Arkansas State University-Jonesboro Method to increase the yield of products in plant material
CA2903693A1 (en) 2013-03-14 2014-10-02 Pioneer Hi-Bred International, Inc. Maize stress related transcription factor 18 and uses thereof
US20140283216A1 (en) 2013-03-15 2014-09-18 Pioneer Hi Bred International Inc Compositions and methods of use of acc oxidase polynucleotides and polypeptides
ES2675362T3 (en) 2013-07-10 2018-07-10 Basf Se RNAi for the control of fungi and phytopathogenic oomycetes by inhibiting CYP51 gene expression
US11053513B2 (en) 2013-07-15 2021-07-06 Donald Danforth Plant Science Center Enhanced oil production and stress tolerance in plants
WO2021007284A2 (en) 2019-07-11 2021-01-14 The Regents Of The University Of California Methods for improved regeneration of transgenic plants using growth-regulating factor (grf), grf-interacting factor (gif), or chimeric grf-gif genes and proteins
EP4346872A1 (en) 2021-06-03 2024-04-10 Mazen Animal Health Inc. Oral administration of coronavirus spike protein for altering cytokine levels and providing passive immunity to newborn pigs

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US5071773A (en) 1986-10-24 1991-12-10 The Salk Institute For Biological Studies Hormone receptor-related bioassays
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US5432068A (en) 1990-06-12 1995-07-11 Pioneer Hi-Bred International, Inc. Control of male fertility using externally inducible promoter sequences
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Also Published As

Publication number Publication date
HUP0103993A3 (en) 2003-10-28
US20030110528A1 (en) 2003-06-12
US7205455B2 (en) 2007-04-17
JP2002525053A (en) 2002-08-13
US20030088890A1 (en) 2003-05-08
AU5915999A (en) 2000-04-03
EP1112360A1 (en) 2001-07-04
AR021484A1 (en) 2002-07-24
WO2000015791A1 (en) 2000-03-23
HUP0103993A2 (en) 2002-01-28
US7151168B2 (en) 2006-12-19
CA2336207C (en) 2004-03-23
US20030131381A1 (en) 2003-07-10
US6504082B1 (en) 2003-01-07
MXPA01002529A (en) 2003-03-10
US7238859B2 (en) 2007-07-03

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