CA2358993A1 - Small volume in vitro analyte sensor and related methods - Google Patents

Small volume in vitro analyte sensor and related methods Download PDF

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Publication number
CA2358993A1
CA2358993A1 CA002358993A CA2358993A CA2358993A1 CA 2358993 A1 CA2358993 A1 CA 2358993A1 CA 002358993 A CA002358993 A CA 002358993A CA 2358993 A CA2358993 A CA 2358993A CA 2358993 A1 CA2358993 A1 CA 2358993A1
Authority
CA
Canada
Prior art keywords
small volume
sensor
analyte
charge
determining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002358993A
Other languages
French (fr)
Other versions
CA2358993C (en
Inventor
Charles T. Liamos
Benjamin J. Feldman
Jeffery V. Funderburk
Rajesh Krishnan
Phillip J. Plante
Joseph A. Vivolo
Robert Y. Jin
Michael S. Cloud
Fredric C. Colman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Therasense Inc
Original Assignee
Therasense, Inc.
Charles T. Liamos
Benjamin J. Feldman
Jeffery V. Funderburk
Rajesh Krishnan
Phillip J. Plante
Joseph A. Vivolo
Robert Y. Jin
Michael S. Cloud
Fredric C. Colman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therasense, Inc., Charles T. Liamos, Benjamin J. Feldman, Jeffery V. Funderburk, Rajesh Krishnan, Phillip J. Plante, Joseph A. Vivolo, Robert Y. Jin, Michael S. Cloud, Fredric C. Colman filed Critical Therasense, Inc.
Priority to CA002423837A priority Critical patent/CA2423837C/en
Publication of CA2358993A1 publication Critical patent/CA2358993A1/en
Application granted granted Critical
Publication of CA2358993C publication Critical patent/CA2358993C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S439/00—Electrical connectors
    • Y10S439/909—Medical use or attached to human body

Abstract

A small volume sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determin e correct positioning of the sensor in a connector. In one embodiment, the sensor determines the concentration of the analyte by discharging an amount of charge into the sample, determining the time needed to discharge the charge, and determining the current used to electrolyze a portion of the analyte usi ng the amount of charge and the amount of time.
CA002358993A 1999-11-04 2000-10-27 Small volume in vitro analyte sensor and related methods Expired - Fee Related CA2358993C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002423837A CA2423837C (en) 1999-11-04 2000-10-27 Small volume in vitro analyte sensor and methods

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/434,026 US6616819B1 (en) 1999-11-04 1999-11-04 Small volume in vitro analyte sensor and methods
US09/434,026 1999-11-04
PCT/US2000/029540 WO2001033216A1 (en) 1999-11-04 2000-10-27 Small volume in vitro analyte sensor and related methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002423837A Division CA2423837C (en) 1999-11-04 2000-10-27 Small volume in vitro analyte sensor and methods

Publications (2)

Publication Number Publication Date
CA2358993A1 true CA2358993A1 (en) 2001-05-10
CA2358993C CA2358993C (en) 2005-08-02

Family

ID=23722510

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002358993A Expired - Fee Related CA2358993C (en) 1999-11-04 2000-10-27 Small volume in vitro analyte sensor and related methods

Country Status (10)

Country Link
US (8) US6616819B1 (en)
EP (1) EP1145000B8 (en)
JP (2) JP2003513279A (en)
KR (1) KR100495935B1 (en)
CN (1) CN1201149C (en)
AT (1) ATE295538T1 (en)
AU (1) AU776764B2 (en)
CA (1) CA2358993C (en)
DE (1) DE60020076T2 (en)
WO (1) WO2001033216A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9835582B2 (en) 2005-09-30 2017-12-05 Ascensia Diabetes Care Holdings Ag Devices using gated voltammetry methods
US9933385B2 (en) 2007-12-10 2018-04-03 Ascensia Diabetes Care Holdings Ag Method of using an electrochemical test sensor
US10067082B2 (en) 2004-02-06 2018-09-04 Ascensia Diabetes Care Holdings Ag Biosensor for determining an analyte concentration
US10190150B2 (en) 2006-10-24 2019-01-29 Ascensia Diabetes Care Holdings Ag Determining analyte concentration from variant concentration distribution in measurable species

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* Cited by examiner, † Cited by third party
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US9835582B2 (en) 2005-09-30 2017-12-05 Ascensia Diabetes Care Holdings Ag Devices using gated voltammetry methods
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US9933385B2 (en) 2007-12-10 2018-04-03 Ascensia Diabetes Care Holdings Ag Method of using an electrochemical test sensor
US10690614B2 (en) 2007-12-10 2020-06-23 Ascensia Diabetes Care Holdings Ag Method of using an electrochemical test sensor

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US6942518B2 (en) 2005-09-13
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US20020053523A1 (en) 2002-05-09
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US6749740B2 (en) 2004-06-15
US20090260985A1 (en) 2009-10-22
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