CA2378064A1 - Electrosurgical probe for tumor treatment by radiofrequency - Google Patents

Electrosurgical probe for tumor treatment by radiofrequency Download PDF

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Publication number
CA2378064A1
CA2378064A1 CA002378064A CA2378064A CA2378064A1 CA 2378064 A1 CA2378064 A1 CA 2378064A1 CA 002378064 A CA002378064 A CA 002378064A CA 2378064 A CA2378064 A CA 2378064A CA 2378064 A1 CA2378064 A1 CA 2378064A1
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CA
Canada
Prior art keywords
cannula
electrodes
electrosurgical probe
probe according
control rod
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002378064A
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French (fr)
Inventor
Francesco Garbagnati
Sandro Rossi
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Invatec SpA
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Individual
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Publication date
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Publication of CA2378064A1 publication Critical patent/CA2378064A1/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1477Needle-like probes

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Otolaryngology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)
  • Radiation-Therapy Devices (AREA)
  • Electrotherapy Devices (AREA)

Abstract

The present invention relates to an electrosurgical probe comprising a metal cannula (1), partially provided with an electroinsulating coating, wherein a multiplicity of filiform electrodes in a stretched position is housed, which are provided with elastic memory for assuming an arched shape by coming out from the cannula (1) this way confining the action of the filiform electrodes to limited, nearly spherical volume. Said electrodes (6) are fixed to the distal end of a control rod (7) also arranged in a slidable way inside the cannula (1), so that the electrodes in a stretched position are arranged side by side parallely with their control rod (7). The cannula (1) is provided with a series of holes (8) each being positioned immediately under the free ends of the filiform electrodes (6) and having a sufficient diameter for the passage of said electrodes. These are taken out of the cannula (1) not by pushing, but by pulling the control rod (7).

Description

11.5ET.2001 1?:Z9 . SIB MILRNO +39-0280633200 NR.380 P.3i3 ,' WO OL853I7 PC?/IT00100301 . ~_. _ I .
~~CTROSURGI~ r.fi'~OR.TIJMOR'f~~~,_T _BY
.
~Q~,7 AEOU~ZtCY"
the present invention relates to as electrosurgical probe far tlae ~
tceby sadiofrequency energy, and pa~al~dy to a probe coatevia~ag a of aeedk-shaped elect~c~odes whose tips can be expanded at tha tmmr to be so as to affect a volume of catuoer tissue which is ss Iarge cg possc'Erlc.
The tumor treatment by hypetthermia which is induced by radiofrequency energy or other enetBy farms is already known in medieiae. Electsosur$ical 14 probes provided with needle-sloped electrodes which, by pinto the cancer tissue, cause its neeros'ss, have already beau developed. WO 96129146 describes electrosurgical probes comprising a muttiplicixy of independent needle shaped electrodes which are pushed inside the tisane to be arexal by making them come out from the-point of a metal cannula inseated into the patient's body.
'Ibis is obtained by usi~~g electrodes formed of thin metal wires having as arched end ~ P .a« , ~~ ore, pP"~
eiaetroprob~'~which ~aLso formed of aaaula o mul~plicriy of f~lifo~r electrodes liaviug arched tips with elastic memory which ate compressed inside the caanula in a stretehcd po 'satiov and which expand themselves whey they are pushed oat of the esnnula iase~d ias3de the tisstu w be treated. Zhe fili~m electrodes are arranged iaaide the caaaula ammzd a camtal nucleon so that, when their tips are pushed out from the point of the caaaula, the cancer tissue is ai~Cted ui a regular volume wliicli is as aseimilable as possible to ° ~ : :: : , _ _ . - -a sphere. ' - .° :' y~.
H~owevez, none of the presently lmomi elecxro~cai probes is capa'fle of creating sa electrical field having a sea! spherical shape, by them it is at the most posssble to obtain as elorrzical field having an ellipsoidal shape since, as it is pravyded with el8stieal memory which is kept in a snbet~ially str~c~hed condition inside said eannula sad is released, .expaa.diung ~itsel~ when.. ~
eleet~odes are pushed out of the caanula is order to penetrate into the tissue to be treated. Object of said expavsioa is that awvr ~ 4 csr ' to be tmated which is as lar as oasible is a$eoted. O desonb et AMENDED SHEET
CAADCAAI/.C'7CTT 11 ('CD 1~.'1A ~mnnnnnvn-rrtr .. urn .~ n.
apparent from figures 4 and 5 of W098/52480, only a small portion of the distal end of the metal caunula, which participates to the formation of the electrical field, is surrounded by the arched ends of the filiform electrodes.
Anotlier drawback of the known electrosurgical probes is that tlieir use involves the risk that the arched ends of the electrodes, by penetrating into the cancer tissue under the impulse of the suitable control, may go beyond the appointed target and penetrate also in vital structures, for instance a blood vessel, adjacent to the portion to be treated.
Tlierefore, object of the present invention is providing an electrosurgical probe of the type with multiple needles liaving an arched point witli elastic memory which is free from the above mentioned drawbacks. Said object is achieved by the electrosurgical probe liaving the features specified in claim 1.
Further features are specified in the following claims.
The electrosurgical probe according to the present invention eliminates the first of the above mentioned drawbacks of the probes according to the prior art, because it has the important feature that the electrodes, when tliey are outside the cannula, are arranged like the meridians of an ideal sphere wliose diameter is formed of a long segment of the cannula distal portion, which is not coated by the insulating material. Accordingly, also the cannula in its distal portion participates in creating the active field of the radiofrequency. As a matter of facts, when the needle-sliaped electrodes protrude fi-om the cannula, the arched portion of each electrode forms au arc of 180° wliose two ends are located near to the two ends of the uncoated distal portion of the caunula, tliat is, near to the two poles of the ideal sphere of wliicli tliat portion of the cannula forms the diameter.
Tlie second of the above mentioned drawbacks of the known electrosurgical probes is eliminated by means of the probe according to the present invention because it lias the feature that the expansion of the arched tips of the electrodes is controlled by traction of the electrodes and not by thrust like in the known probes.
In otlier words, whereas in the known probes the expansion of the filiform electrodes is controlled by a movement in the same direction of penetration of the electrodes into the patient's tissues, in the probe according to the present invention the expansion is controlled by traction, that is by a movement in the opposite direction with respect to that of penetration of the electrodes into the patient's tissues. Resultingly, the flee end of each filiform electrode will have the tendency to converge, after the expansion movement, towards the distal end of the metal cannula, thus avoiding the risk that it may diverge towards vital structures and perforate them. Tliis is due to the fact that in the probe according to the present invention, in the rest position thereof, both the filiform electrodes and the rod wliicli controls tliem liave the same direction but they are turned in different directions after the expansion.
Besides eliminating the above mentioned drawbacks of the probes according to the prior art, the electrosurgical probe according to the present invention offers anotlier important advantage, tliat is avoiding, during said operation, that the electrodes come out accidentally from the probe point during the positioning operation of the probe itself into the tissue. This is due to the fact that the operation for causing the electrodes expansion takes place by retraction with a movement in the opposite sense witli respect to the positioning movement, and not in the same sense like in the prior ait.
A fizrtlier advantage of the electrosurgical probe according to the present invention with respect to the prior art is that no fi~ee space between the distal end of the cannula and the content thereof is provided. As a matter of fact, said fi~ee space, which is present in the known probes, may cause undesired phenomena of core boring of healthy tissue of the patient during the probe positioning operation.
The structure of the probe according to the present invention allows also to close the distal end of the cannula and to confer it a pointed tip.
These and other advantages of the electrosurgical probe according to the present invention will be evident to those skilled in the art fiom the following detailed description of one embodiment thereof with reference to the accompanying drawings, wherein:
- figure 1 shows an enlarged and partially sectioned view in side elevation of the canuula of the probe according to the present invention;
- figure 2 shows a similar view of the same cannula of figure l, but with the arclied tips of the electrodes taken out from the cannula and in the working position; and - figure 3 sliows a view in scale of a complete electrosurgical probe with the electrodes in the working position.
Witli reference to figure 1 there is shown that the electrosurgical probe according to the present invention comprises a metal cannula 1, of a known kind, inside which a liead 3 is placed, having the upper end 4 preferably pointed like a flute moutlipiece. Also the point of cannula 1 can be pointed like a flute moutlipiece like the upper end 4 of head 3. In this way, the point of head 3 can coincide in the rest position witli the point of cannula 1 without any free space between the two points. This structural measure avoids the undesirable phenomena of core boring of healthy parencliymatous tissue whicli occur by using the probes according to the prior art wherein a free space between the piston head wliich pushes the electrodes and the point of the cannula whicli contains tliem necessarily exists. It is obvious tliat the point of liead 3 in the rest position can also protrude from the end 2 of the cannula, because tliis is open. However, constructive variants are possible, with a closed and sliaip point of cannula 2, or with an open canuula 2 and a pointed head 3 like in figure 2. Otlier embodiments are obviously possible in order to fix the base of the electrodes to the distal end of tlieir control rod so that in the stretched position they are side by side with said axis.
From base 5 of liead 3 a multiplicity of filiform electrodes 6, as well as control rod 7 of head 3, branch off downwards. This is the most innovative and advantageous feature of the electrosurgical probe according to the present invention, witli respect to tliat of the prior art wherein the electrodes in the stretched position form the prolongation of the electrode control rod and are not at the side tliereof. The filiform electrodes liaving elastic memory of shape are already known in the art and therefore they do not need a detailed description.
The filiform electrodes 6 are arranged on the side and parallel to rod 7 in a stretched position with tlieii~ downward turned tips whicli are near or sliglitly above a multiplicity of lioles 8 arranged along the circumference of cannula 1.
The number of holes 8 corresponds to the number of electrodes 6 so tliat each electrode 6 has a relevant hole 8 for coming out of canuula 1 when rod 7 of head 3 is pulled downwards. Holes 8 are arranged in such a way that each of the electrode points can pass through the relevant hole 8 in order to get out of cannula 1 under the thrust of liead 3 wlien this is pulled downwards. As soon as rod 7 is pulled downwards, electrodes 6 come out of holes 8 of canuula 1, gradually regaining their naturally arched shape by virtue of their elastic memory, thus assuming in the end the configuration shown in figure 2.
Witli reference to figure 2, there is shown that each electrode 6, after passing through the relevant hole 8, under the tlwust of liead 3 wliich is pulled downwards by means of control rod 7, has passed nearly completely through the relevant holes 8, thus penetrating in the cancer tissue to be treated or surrounding it. In the course of said penetration, by viirtue of the elastic memory of which filiform electrodes 6 are provided, tliese expand tliemselves wliile bending until they assume the position shown in the figure. As it can be seen, eacli electrode 6 has assumed a position which greatly resembles that of a meridian of an ideal sphere. Said shape is much more regular tlian those which can be obtained by the electrosurgical probes according to the prior au. Said regularity depends substantially on the fact that filiform electrodes 6 are not only pushed inside the cancerous tissue, like in the known electrosurgical probes, but they are also guided from the lower ends of the relevant holes 8 suitably provided along the circumference of cannula 1.
Holes 8 can have any suitable shape for favoring the coming out of the needle-shaped electrodes and for guiding them upwards as soon as they come out from cannula 1. The prefeiTed sliape for holes 8 is the one slightly lengthened in the direction of the length of the needle-shaped electrode so as to favor the coming out thereof from cannula 1. The lower rim of the hole is provided with a profiled upward-turned cross-section wliich forms an upward-directed guide plane for the needle-sliaped electrode which helps it in its expansion until it reaches the position shown in the figure.
Obviously, the number of the holes depends on the number of the filiform electrodes. Their number varies according to the needs and can vary between two and twenty. In the embodiment shown in the figures 1-3 they are four. When the number of the filiform electrodes is very higli, it is preferable that holes 8 are not circumferentially aligned on the surface of cannula l, but arranged according to an elicoidal line or on more parallel circumferences.
Cannula 1 is provided with an insulating coating 9 of a plastic material whose upper edge is positioned slightly under the last of holes 8. In tliis way, the exposed portion of metal cannula 1 during working forms the diameter of the ideal sphere created by the envelope of the needle-shaped electrodes.
With reference to figure 3 there is sliown au electrosurgical probe according to the present invention in the working position. In said position, the filiform electrodes 6 are already expanded and their points liave reached a position very close to the distal end 2 of cannula 1. The coming out of electrodes 6 from the inside of cannula 2 has been caused by moving away head 3 fi~om distal end 2 of the cannula. Said movement away has been achieved by pulling control rod 7 by means of knob 9 which is thus progressively removed fi~om handle 10 which is internally provided with a room suitable for housing stem 11 of knob 9.
In figure 3 there is also shown the independent lateral needle 14 which works as a support for one or more thermistors of the teletliermometnc system applicable to the probe according to the present invention. Needle 14 comes out of cannula 1 tlirough a suitable hole 15 made on the cannula and is controlled by cursor 12 wliicli is partially housed inside knob 10. Further to lateral needle 14, the probe according to the present invention can be provided with one or more similar needles. Each one of needles 14 carrying thernustors can be rendered radiofrequency active at discretion, thus enlarging the extent of the thermolesion.
Obviously, the probe according to the present invention can be completed with the necessary connections to the radiofrequency generator and with all the other attachments necessary for its working, maintenance and use, as well as for the telethermometric check of the thermal lesion during the treatment.
In a preferred embodiment of the present invention, a thermistor has been applied on each end of the non insulated portion of cannula 1. A third thermistor _'7_ lias been advantageously applied also on the insulated portion of canuula l, immediately under holes 8.
Rigid cannula 1 can be replaced by a flexible tube in a portion comprised between the line of the holes 8 and handle 10. Said embodiment allows the probe to be used as a catheter.

Claims

1. Electrosurgical probe comprising a metal cannula (1) provided with an electroinsulating coating wherein a multiplicity of filiform electrodes (6) is housed in a stretched position, which are provided with elastic memory for assuming an arched shape when they come out of the cannula (1) and fixed to the distal end of a control rod (7), this being also positioned in a slidable way inside the cannula (1), characterized in that the electrodes in a stretched position are arranged side by side parallely to their control rod (7) and that the cannula (1) is provided with a set of holes (8) each of which is positioned immediately under the free ends of the filiform electrodes (6) and have sufficient diameter for the passage of said electrodes.
2. Electrosurgical probe according to claim 1, characterized in that the distal end of the cannula (1) is provided with a segment which is not provided with an electroinsulating coating, said segment ending under holes (8).
3. Electrosurgical probe according to claim 1 or 2, characterized in that the electrodes (6) are fixed to the lower face (5) of a head (3) mounted on the distal end of the control rod (7).
4. Electrosurgical probe according to claim 3, characterized in that the rod (7) at the opposite end with respect to the one whereto the head (3) is fixed, is provided with a knob (9) for the seize thereof.
5. Electrosurgical probe according to claim 4, characterized in that the cannula (1) is provided with an internally hollow handle (10), for passing the rod (7) and for housing the stem (11) of knob (9).
6. Electrosurgical probe according to one or more preceding claims, characterized in that the holes (8) are in a number from one to twenty.
7. Electrosurgical probe according to one or more of the preceding claims, characterized in that it is provided with one or more needles (14) which bear, on the tip thereof, a thermistor for the control of the temperature.
8. Electrosurgical probe according to claim 7, characterized in that each of the needles (14) can be made radiofrequency active.
9. Electrosurgical probe according to one or more of the preceding claims, CLAIM
1. Electrosurgical probe comprising a metal cannula (1) provided with an electroinsulating coating, wherein is housed in a stretched position a multiplicity of filiform electrodes (6) having elastic memory for assuming an arched shape when they come out of the cannula (1) and fixed to the distal end of a control rod (7) also positioned in a slidable way inside cannula (1), characterized in that electrodes (6) in the stretched position are arranged side by side parallely to their control rod (7) with their free ends positioned in correspondence of a plurality of circumpherential holes (8) each of them having a diameter suitable for the passage therethrough of said electrodes (6) which in their expanded state extend along the meridian of a sphere having its center inside said cannula (1), the expansion of electrodes (6) being controllable by proximally retracting the control rod (7) of electrodes (6).

characterized in that between the line of the holes (8) and the handle (10) the rigid cannula (1) is replaced by a segment of flexible tube.
CA002378064A 1999-07-21 2000-07-19 Electrosurgical probe for tumor treatment by radiofrequency Abandoned CA2378064A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT1999MI001608A ITMI991608A1 (en) 1999-07-21 1999-07-21 ELECTROSURGICAL PROBE FOR TREATMENT OF TUMORS BY RADIOFREQUENCY
ITMI99A001608 1999-07-21
PCT/IT2000/000301 WO2001005317A1 (en) 1999-07-21 2000-07-19 Electrosurgical probe for tumor treatment by radiofrequency

Publications (1)

Publication Number Publication Date
CA2378064A1 true CA2378064A1 (en) 2001-01-25

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CA002378064A Abandoned CA2378064A1 (en) 1999-07-21 2000-07-19 Electrosurgical probe for tumor treatment by radiofrequency

Country Status (15)

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US (1) US6623481B1 (en)
EP (1) EP1199998B1 (en)
JP (1) JP3811065B2 (en)
CN (1) CN1275575C (en)
AT (1) ATE292422T1 (en)
AU (1) AU768134B2 (en)
BR (1) BR0012617B1 (en)
CA (1) CA2378064A1 (en)
DE (1) DE60019294T2 (en)
ES (1) ES2240137T3 (en)
HK (1) HK1048746B (en)
IL (1) IL147663A (en)
IT (1) ITMI991608A1 (en)
MX (1) MXPA02000797A (en)
WO (1) WO2001005317A1 (en)

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Publication number Publication date
EP1199998A1 (en) 2002-05-02
DE60019294T2 (en) 2006-05-18
BR0012617A (en) 2002-04-09
CN1361676A (en) 2002-07-31
JP3811065B2 (en) 2006-08-16
ES2240137T3 (en) 2005-10-16
IL147663A (en) 2006-09-05
ITMI991608A0 (en) 1999-07-21
DE60019294D1 (en) 2005-05-12
HK1048746A1 (en) 2003-04-17
JP2003504146A (en) 2003-02-04
US6623481B1 (en) 2003-09-23
MXPA02000797A (en) 2003-07-14
WO2001005317A1 (en) 2001-01-25
IL147663A0 (en) 2002-08-14
ATE292422T1 (en) 2005-04-15
CN1275575C (en) 2006-09-20
EP1199998B1 (en) 2005-04-06
ITMI991608A1 (en) 2001-01-21
AU6468000A (en) 2001-02-05
BR0012617B1 (en) 2009-01-13
HK1048746B (en) 2007-01-12
AU768134B2 (en) 2003-12-04

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