CA2383926A1 - Functional genomics using zinc finger proteins - Google Patents

Functional genomics using zinc finger proteins Download PDF

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Publication number
CA2383926A1
CA2383926A1 CA002383926A CA2383926A CA2383926A1 CA 2383926 A1 CA2383926 A1 CA 2383926A1 CA 002383926 A CA002383926 A CA 002383926A CA 2383926 A CA2383926 A CA 2383926A CA 2383926 A1 CA2383926 A1 CA 2383926A1
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zinc finger
finger proteins
functional genomics
genomics
functional
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CA2383926C (en
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Casey C. Case
Lei Zhang
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Sangamo Therapeutics Inc
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
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    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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Abstract

The present invention provides methods of regulating gene expression using recombinant zinc finger proteins, for functional genomics and target validation applications.
CA002383926A 1999-09-14 2000-09-12 Functional genomics using zinc finger proteins Expired - Lifetime CA2383926C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/395,448 US6599692B1 (en) 1999-09-14 1999-09-14 Functional genomics using zinc finger proteins
US09/395,448 1999-09-14
PCT/US2000/024897 WO2001019981A2 (en) 1999-09-14 2000-09-12 Functional genomics using zinc finger proteins

Publications (2)

Publication Number Publication Date
CA2383926A1 true CA2383926A1 (en) 2001-03-22
CA2383926C CA2383926C (en) 2008-09-09

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CA002383926A Expired - Lifetime CA2383926C (en) 1999-09-14 2000-09-12 Functional genomics using zinc finger proteins

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US (3) US6599692B1 (en)
EP (1) EP1238067B1 (en)
JP (3) JP2003527093A (en)
KR (1) KR20020065473A (en)
AT (1) ATE313625T1 (en)
AU (1) AU778964B2 (en)
CA (1) CA2383926C (en)
DE (1) DE60025037T2 (en)
HK (1) HK1049501B (en)
WO (1) WO2001019981A2 (en)

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